EKS-GAA-00305

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00305

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	325.9	2.0E-97	19	269	251

Status

Unreviewed

Ensembl Protein

ENSGACP00000001370

UniProt Accession

G3N7T6;

Protein Name

Protein Synonyms/Alias

Gene Name

NUAK2

Gene Synonyms/Alias

NUAK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000001061	ENSGACP00000001370	ENSGACT00000001371

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

588

Protein Sequence
(FASTA)

VRRQAVKRHH HKHNLKHRYE FMETLGKGTY GKVKKAEERS GRLVAIKSIR KEKIKDEQDL 60

VHIRREIEIM SSLCHPHITT IYEVFENKDK IVIVMEYASR GDLYDYVCDK RNISEREARH 120

FFRQIVSAVH YCHQNGIVHR DLKLENILLD GNGNVKIADF GLSNLFHGDE YLRTFCGSPL 180

YASPEIVNGR PYRGPEVDTW SLGVLLYTMV HGNMPFDGNN HKALVQQIST GNYRKPINPS 240

DACGLIRWML MVNPERRATI EEIAGHWWLN WGYQQPLLAE AKSSPVEQNS PPAPASASYP 300

AGLALVGSWL RRTSRPLLEN GSKMRCLLRS QGGGGDVVRQ RSLRRSRKEN NVSQTIHEVG 360

PESRPSKGIL KKRNSVKQKA TSEVPAVGSV EPKKLLGLPA PADAPSAALL PRKGILKKRA 420

GQESGYYSSS PENSDSGWAS QTKECPSAPT HRKGILKRNG KFSSGRLQEF GSLDQLAASL 480

PCGGVSSRPG GAVSADSILS SESFDQLDLP DRVGPPAQME KPAKSSMRGC VSADNLLDIT 540

EDGILGGGSL RPWNCYRSGV ADSAFSITDC DNVTEAYKRA VAVRGSAA 588

Nucleotide Sequence
(FASTA)

GTGAGGAGAC AAGCCGTGAA GAGACACCAC CACAAACACA ACCTGAAGCA CAGGTACGAG 60

TTCATGGAGA CCCTCGGCAA AGGAACCTAC GGCAAGGTGA AGAAGGCCGA GGAGAGATCG 120

GGCCGACTGG TTGCCATAAA GTCTATCCGA AAGGAGAAGA TAAAGGATGA GCAAGATCTG 180

GTTCATATTC GCAGAGAAAT TGAAATCATG TCCTCGCTCT GCCATCCTCA CATCACCACC 240

ATATATGAAG TATTTGAGAA CAAGGACAAA ATTGTGATCG TGATGGAGTA CGCCAGCCGA 300

GGGGACCTGT ACGACTACGT CTGTGACAAG CGGAACATCT CTGAACGCGA GGCCAGGCAC 360

TTCTTCAGAC AAATCGTGTC CGCTGTGCAC TACTGCCATC AGAATGGAAT AGTACACCGG 420

GACCTGAAAC TGGAAAATAT TTTACTAGAT GGCAACGGCA ATGTGAAGAT CGCAGACTTT 480

GGGTTGTCAA ACCTCTTCCA TGGTGATGAG TACCTTCGAA CCTTTTGTGG AAGCCCTCTA 540

TATGCTTCCC CGGAGATCGT CAATGGGCGG CCGTACCGTG GGCCGGAGGT GGACACTTGG 600

TCTCTGGGTG TGCTACTGTA CACCATGGTT CATGGTAATA TGCCATTCGA CGGAAACAAC 660

CACAAGGCAT TGGTCCAACA GATAAGCACC GGAAACTATC GTAAACCCAT CAATCCCTCT 720

GACGCATGTG GGCTTATCCG TTGGATGCTG ATGGTCAATC CTGAGCGCAG AGCCACAATC 780

GAGGAGATTG CAGGACACTG GTGGCTCAAC TGGGGCTATC AGCAGCCGTT ACTGGCTGAG 840

GCAAAGAGCA GTCCAGTGGA GCAGAACTCT CCACCAGCCC CGGCATCAGC GTCCTATCCT 900

GCCGGGCTGG CCCTTGTTGG AAGTTGGCTG CGTCGAACAT CCAGGCCTTT GCTGGAGAAC 960

GGCTCCAAGA TGCGCTGCCT GCTCCGCTCG CAGGGCGGCG GAGGGGACGT GGTCCGGCAA 1020

CGGTCTCTCC GACGGTCCCG AAAGGAAAAT AACGTCTCCC AGACCATTCA CGAAGTAGGA 1080

CCTGAGAGTC GTCCCTCTAA GGGGATCCTA AAGAAACGCA ACAGTGTGAA GCAGAAGGCC 1140

ACGAGCGAAG TCCCTGCTGT AGGTTCAGTG GAGCCAAAGA AGCTTTTGGG TTTGCCTGCA 1200

CCAGCTGATG CTCCTTCAGC TGCTCTGCTG CCTCGCAAAG GTATCCTAAA GAAGCGAGCA 1260

GGGCAAGAGT CCGGGTACTA CTCCTCCTCT CCCGAGAACA GCGACTCTGG CTGGGCTTCA 1320

CAGACCAAAG AGTGCCCTTC AGCGCCCACT CATAGGAAAG GCATCTTGAA GCGCAACGGG 1380

AAGTTCTCCT CGGGTAGGCT GCAGGAGTTT GGCTCTCTGG ATCAGCTGGC GGCTTCTCTA 1440

CCCTGCGGTG GCGTCAGCTC GAGACCCGGC GGGGCGGTCA GCGCGGACAG CATTCTGTCC 1500

TCCGAGTCCT TCGACCAGCT GGATCTGCCG GACCGCGTGG GACCTCCGGC ACAAATGGAG 1560

AAACCAGCCA AGTCGAGCAT GAGGGGATGC GTGTCTGCTG ACAACCTGCT GGACATCACA 1620

GAGGACGGGA TCCTCGGGGG CGGGTCTCTG AGGCCCTGGA ACTGCTACCG GTCTGGAGTG 1680

GCTGACAGCG CCTTTTCCAT CACAGACTGT GATAATGTGA CGGAGGCCTA CAAACGGGCC 1740

GTGGCTGTAC GAGGCTCTGC AGCA 1764

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y++++tlG+g++gkVk+a+++  ++ va+K i+k+k+ +e+ l +i+rEiei+++l hp+

Q: 19    YEFMETLGKGTYGKVKKAEER-SGRLVAIKSIRKEKIkDEQDLVHIRREIEIMSSLCHPH  77

         99***************9887.799**********996777899****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         i+ ++ev+e+k+k+++v+eyas+g+L+dy+ +k++++e+ear++f+q+vsav+Y+h++gi

Q: 78    ITTIYEVFENKDKIVIVMEYASRGDLYDYVCDKRNISEREARHFFRQIVSAVHYCHQNGI  137

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlK+eN+lld ++n+kiaDFGl+nlf+ ++ l+tfcGsp Ya+Pe+++g++Y+gp+v

Q: 138   VHRDLKLENILLDGNGNVKIADFGLSNLFHGDEYLRTFCGSPLYASPEIVNGRPYRGPEV  197

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D WslGv+Ly++v g++Pfd++n k+l+++i++g+++ p + s ++  L+r +L+v+pe+

Q: 198   DTWSLGVLLYTMVHGNMPFDGNNHKALVQQISTGNYRKPINPS-DACGLIRWMLMVNPER  256

         ***************************************9966.5668************

S: 240   Ratieeilkhewl  252

         Ratieei  h wl

Q: 257   RATIEEIAGHWWL  269

         ************7

Domain Sequence
(FASTA)

YEFMETLGKG TYGKVKKAEE RSGRLVAIKS IRKEKIKDEQ DLVHIRREIE IMSSLCHPHI 60

TTIYEVFENK DKIVIVMEYA SRGDLYDYVC DKRNISEREA RHFFRQIVSA VHYCHQNGIV 120

HRDLKLENIL LDGNGNVKIA DFGLSNLFHG DEYLRTFCGS PLYASPEIVN GRPYRGPEVD 180

TWSLGVLLYT MVHGNMPFDG NNHKALVQQI STGNYRKPIN PSDACGLIRW MLMVNPERRA 240

TIEEIAGHWW L 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013