EKS-GAA-00252

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00252

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	493.5	2.4E-148	4	284	281

Status

Unreviewed

Ensembl Protein

ENSGACP00000003064

UniProt Accession

G3NCK8;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000002347	ENSGACP00000003058	ENSGACT00000003069
ENSGACG00000002347	ENSGACP00000003064	ENSGACT00000003075

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

620

Protein Sequence
(FASTA)

MNRYTTLKQL GDGTYGSVLM GRSNESGELV AIKRMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFVFE YMKENLYQLM KDRKRLFPES VIRNIGFQIL QGLSFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREI RSKPPYTDYV STRWYRAPEV LLRSSTYSSP 180

IDLWAVGCIM AELYTLRPLF PGNSEVDEIF KICQVLGTVK KTDWSEGHQL ASAMNFRFPQ 240

CVPTHLKTLI PNASNEAIAL MRDLLQWDPK KRPTAVQTLR YPYFQVGQIL GPRPLSQEVK 300

NIQARPPAQK QVSDSKADPQ QSSSESKTST SSSRNQHHQP LQQIPLPQTE NPIRLLSRGV 360

RPVSQLCRPH PQKAAPLGGD GSVGGAGMGV LKNGRRRWGQ TAAKTSDSWE ESDPAETTAS 420

NSKKPSLGNA EEEEEASLKE HRPHTVTKLP NNVKIGQMDS NLSGSAARQH YLSQSRYLPG 480

LIGKSQTSAD KKLSGLTLRD LWENSSNTLN KPLAPIGGGL SVTRDNTGNF ISTKYNLSGG 540

YIPSFQKKEV GSVGQRIQLA PLDSQHTNYE GWKRRADRTQ MKGSSYSALG KTSGNLLSRA 600

PPAQPVHGRV DWTSKYGANR 620

Nucleotide Sequence
(FASTA)

ATGAATCGCT ACACCACCCT GAAGCAGCTG GGCGATGGCA CCTATGGCAG CGTGCTGATG 60

GGGAGAAGCA ACGAGTCTGG AGAACTGGTG GCTATCAAGA GAATGAAGAG GAAGTTTTAT 120

TCATGGGAAG AATGTATGAA CCTAAGAGAG GTCAAGTCGC TGAAGAAGCT GAACCATGCG 180

AATGTGGTGA AACTGAAGGA GGTCATCAGA GAGAACGATC ACCTCTACTT TGTCTTTGAG 240

TATATGAAGG AGAACCTGTA CCAGCTTATG AAGGACAGAA AAAGGTTGTT TCCCGAATCA 300

GTGATAAGAA ACATAGGCTT TCAGATTTTA CAAGGCCTGT CATTTATTCA CAAACATGGT 360

TTCTTTCACC GAGACATGAA GCCAGAGAAT CTGCTGTGCA TGGGTCCAGA ACTGGTCAAA 420

ATAGCAGATT TCGGACTGGC CCGAGAGATC CGGTCCAAGC CGCCCTACAC AGACTACGTG 480

TCTACCAGAT GGTACCGAGC TCCAGAGGTG CTGCTCAGGT CCTCTACCTA CAGCTCTCCT 540

ATTGACCTGT GGGCTGTGGG CTGCATCATG GCAGAACTCT ACACACTCCG TCCCCTTTTC 600

CCGGGGAACA GTGAGGTGGA TGAGATATTT AAGATCTGCC AAGTCCTTGG CACAGTCAAA 660

AAGACGGATT GGTCAGAAGG CCACCAGTTA GCCTCCGCTA TGAACTTTCG CTTTCCCCAA 720

TGCGTGCCGA CCCACCTGAA GACACTCATC CCTAATGCCA GCAATGAGGC TATCGCCCTG 780

ATGAGGGATC TGCTGCAGTG GGACCCCAAA AAAAGACCCA CTGCTGTACA GACCCTGCGC 840

TACCCTTACT TCCAGGTAGG ACAGATCTTA GGGCCTCGCC CTCTGAGCCA AGAGGTCAAG 900

AACATCCAGG CCAGGCCGCC GGCCCAGAAG CAGGTGTCGG ACTCCAAGGC GGATCCTCAG 960

CAGTCTTCCT CTGAGTCCAA AACCTCCACG TCCTCTTCCA GGAACCAACA TCATCAGCCT 1020

CTCCAGCAGA TTCCCCTTCC TCAGACTGAG AACCCCATTA GACTCCTCTC CCGAGGAGTG 1080

AGACCTGTAA GCCAATTGTG TCGTCCTCAC CCGCAGAAAG CTGCGCCGCT GGGCGGTGAC 1140

GGCAGCGTCG GTGGTGCTGG GATGGGGGTG CTGAAAAATG GCCGTCGTCG CTGGGGCCAG 1200

ACGGCGGCCA AGACATCAGA CAGCTGGGAG GAATCCGACC CGGCTGAAAC CACCGCCTCC 1260

AACTCGAAGA AACCCAGCCT GGGGAACGCG GAGGAGGAGG AGGAGGCGAG CCTGAAGGAG 1320

CACCGCCCAC ACACAGTCAC TAAGCTACCC AACAACGTTA AGATCGGCCA AATGGACTCT 1380

AATCTCTCAG GATCGGCTGC ACGGCAGCAC TATCTGAGCC AGTCGCGATA CTTGCCAGGT 1440

TTGATCGGCA AGAGTCAGAC TTCTGCTGAT AAGAAGCTGA GTGGTTTGAC GCTGCGGGAC 1500

TTGTGGGAGA ACTCCTCAAA CACCTTAAAT AAACCGCTCG CTCCTATTGG AGGAGGATTA 1560

TCTGTCACTC GAGACAACAC AGGGAACTTC ATAAGCACCA AATATAACCT CTCCGGCGGT 1620

TATATACCTT CATTCCAAAA GAAGGAGGTG GGCTCGGTGG GGCAGAGAAT CCAGCTCGCC 1680

CCTTTGGACA GCCAGCACAC AAATTACGAG GGCTGGAAGA GGAGGGCAGA CAGAACTCAG 1740

ATGAAGGGCA GCAGCTACTC GGCTTTGGGC AAAACCTCCG GCAATCTCCT GAGCAGAGCT 1800

CCCCCCGCGC AGCCGGTCCA CGGCCGGGTG GACTGGACAT CCAAATATGG TGCAAATCGG 1860

TAG 1863

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+vl+++s+++gelvaik+mkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTLKQLGDGTYGSVLMGRSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+v+e+m+enlyql+kdr++l++es++++i +qil+gl+fihkhg

Q: 63    VKLKEVI--RENDHLYFVFEYMKENLYQLMKDRKRLFPESVIRNIGFQILQGLSFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rsk+PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSSTYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlwavGc++ae+++lrplfPG se+d+ifki++vlGt kk++w+e+++lasa+n++fpq

Q: 181   IDLWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKTDWSEGHQLASAMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++++ lktl++nas+ea+ l++dll++dP++r+ta q+l+ypyf

Q: 241   CVPTHLKTLIPNASNEAIALMRDLLQWDPKKRPTAVQTLRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTLKQLGDG TYGSVLMGRS NESGELVAIK RMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR KRLFPESVIR NIGFQILQGL SFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLAREIRSK PPYTDYVSTR WYRAPEVLLR SSTYSSPIDL 180

WAVGCIMAEL YTLRPLFPGN SEVDEIFKIC QVLGTVKKTD WSEGHQLASA MNFRFPQCVP 240

THLKTLIPNA SNEAIALMRD LLQWDPKKRP TAVQTLRYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013