EKS-GAA-00074

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00074

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	414.0	3.9E-124	4	287	284

Status

Unreviewed

Ensembl Protein

ENSGACP00000003301

UniProt Accession

G3ND96;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK1

Gene Synonyms/Alias

CDK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000002518	ENSGACP00000003310	ENSGACT00000003321
ENSGACG00000002518	ENSGACP00000003301	ENSGACT00000003312
ENSGACG00000002518	ENSGACP00000003296	ENSGACT00000003307

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

303

Protein Sequence
(FASTA)

MEDYLKIEKI GEGTYGVVYK GRHKATGQIV AMKKIRLESE EEGVPSTAVR EVSLLQELKH 60

PNVVRLLDVL MQESRLYLIF EFLSMDLKKY LDSIPSGQYM DPMLVKSYLY QILEGIYFCH 120

CRRVLHRDLK PQNLLIDNKG VIKLADFGLA RAFGVPVRVY THEVVTLWYR APEVLLGSPR 180

YSTPVDVWST GTIFAELATK KPLFHGDSEI DQLFRIFRTL GTPNNDVWPE VESLPDYKNT 240

FPKWKCGNLS SMVKNLDKNG LDLLAKMLIY NPPKRISARE AMTHAYFEDL DKSTLPAASI 300

NKI 303

Nucleotide Sequence
(FASTA)

ATGGAAGACT ATCTGAAGAT AGAAAAGATT GGAGAAGGGA CGTATGGGGT GGTGTATAAG 60

GGCAGGCACA AGGCTACGGG GCAGATTGTG GCTATGAAGA AGATCCGCCT GGAGAGCGAA 120

GAGGAGGGCG TCCCCAGCAC CGCCGTCAGA GAGGTGTCTC TGCTTCAGGA GCTGAAGCAT 180

CCCAACGTTG TACGACTCCT GGATGTGCTG ATGCAGGAGT CGCGTCTTTA CCTCATCTTT 240

GAGTTCCTGT CCATGGACCT GAAGAAGTAC CTGGACTCCA TCCCCTCCGG CCAGTACATG 300

GACCCTATGC TGGTCAAGAG CTACCTTTAC CAGATCCTGG AGGGCATCTA CTTCTGTCAC 360

TGTCGGCGAG TCCTCCACCG GGACCTGAAA CCCCAAAACC TGCTGATCGA CAACAAAGGG 420

GTTATCAAAC TGGCAGACTT TGGCCTTGCT CGGGCCTTTG GTGTTCCTGT CAGGGTCTAC 480

ACCCATGAGG TGGTGACTCT GTGGTACCGA GCTCCAGAGG TGCTCCTGGG TTCCCCCCGA 540

TACTCGACCC CCGTTGACGT CTGGAGCACT GGGACCATCT TTGCAGAGCT TGCCACTAAG 600

AAGCCTCTGT TCCATGGAGA CTCCGAGATA GACCAGCTCT TCAGGATCTT CAGGACTCTG 660

GGGACCCCGA ACAATGACGT GTGGCCTGAA GTAGAGAGTC TACCCGACTA CAAAAACACT 720

TTCCCCAAAT GGAAGTGTGG CAACCTGTCC TCGATGGTGA AGAACCTGGA CAAGAATGGC 780

CTGGACTTGC TGGCGAAAAT GCTGATCTAC AACCCCCCCA AAAGGATCTC CGCCCGCGAG 840

GCTATGACAC ACGCCTACTT TGAGGACTTG GACAAGTCCA CCCTGCCTGC TGCCAGCATC 900

AACAAAATCT AA 912

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y k+ekigeGtyg+vyk+++k tg++vA+Kkirle+e+egvp+ta+rE+sll+elkh+n+

Q: 4     YLKIEKIGEGTYGVVYKGRHKATGQIVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV  63

         779*********************************************************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkk.klsleevkslllqlleglaylHsn  119

         v+Ll+v++ ++++lyL+fefl++dLkk+l++ ++  ++++  vks+l+q+leg+ ++H +

Q: 64    VRLLDVLM-QESRLYLIFEFLSMDLKKYLDSIPSGqYMDPMLVKSYLYQILEGIYFCHCR  122

         ********.99********************98765999*********************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         ++lHRDlKpqNlLi+++g++klaDfGlaraf++p++ yt+evvTlwYraPe+Llg+ +Ys

Q: 123   RVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYS  182

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykksfp  239

         t vD+Ws g i+ael+t+kplf+g+seidql+rif++lgtp+++vwpev++lp+yk++fp

Q: 183   TPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPEVESLPDYKNTFP  242

         ************************************************************

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k  +l+++vk+l++++ldll k+l ++p kRisa+ea++h yf

Q: 243   KWKCGNLSSMVKNLDKNGLDLLAKMLIYNPPKRISAREAMTHAYF  287

         ********************************************9

Domain Sequence
(FASTA)

YLKIEKIGEG TYGVVYKGRH KATGQIVAMK KIRLESEEEG VPSTAVREVS LLQELKHPNV 60

VRLLDVLMQE SRLYLIFEFL SMDLKKYLDS IPSGQYMDPM LVKSYLYQIL EGIYFCHCRR 120

VLHRDLKPQN LLIDNKGVIK LADFGLARAF GVPVRVYTHE VVTLWYRAPE VLLGSPRYST 180

PVDVWSTGTI FAELATKKPL FHGDSEIDQL FRIFRTLGTP NNDVWPEVES LPDYKNTFPK 240

WKCGNLSSMV KNLDKNGLDL LAKMLIYNPP KRISAREAMT HAYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013