EPS-GAA-00035

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAA-00035

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	265.5	8.2E-79	23	288	266

Status

Unreviewed

Ensembl Protein

ENSGACP00000003656

UniProt Accession

G3NEA7;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1B

Gene Synonyms/Alias

PPM1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000002795	ENSGACP00000003658	ENSGACT00000003670
ENSGACG00000002795	ENSGACP00000003656	ENSGACT00000003668

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

382

Protein Sequence
(FASTA)

MGAFLDKPKT EKHSAHGEGN GLRYGLSSMQ GWRVEMEDAH TAAVGLPHGL TDWSFFAVYD 60

GHAGSRVANY CSGHLLEHIL SGGADFSSGS GCVEGVKDGI RSGFLNIDEY MRSFADLRQG 120

LDRSGSTAVC VLLSPSHLYF INCGDSRAVL SRDGKVGFST QDHKPCNPRE KERIQNAGGS 180

VMIQRVNGSL AVSRALGDYD YKCVDGKGPT EQLVSPEPEV CVLERAAEGD EFVVLACDGI 240

WDVMSNEELC DFVRSRLLVC DVLEKVCNAV VDTCLHKGSR DNMSVVLVCL PGAPKISEEA 300

VKKEEELDKY LETRVEELLG NCGEAGVPDL VSVLRSIATE NIPNLPPGGG LASKRSVIEA 360

VYNKLNPHRE EEGSAGELED PW 382

Nucleotide Sequence
(FASTA)

ATGGGTGCAT TCCTGGACAA GCCGAAGACG GAGAAGCATA GTGCCCACGG CGAGGGCAAT 60

GGGCTGCGCT ACGGCCTGAG CTCCATGCAG GGCTGGCGGG TGGAGATGGA GGACGCCCAC 120

ACGGCCGCGG TGGGCCTCCC CCACGGACTC ACCGACTGGT CCTTCTTTGC TGTCTACGAT 180

GGCCACGCCG GCTCCCGGGT GGCCAACTAC TGCTCCGGCC ACTTGCTGGA ACACATCTTG 240

TCGGGCGGGG CCGACTTCAG TTCAGGATCC GGCTGCGTGG AGGGAGTGAA GGACGGCATC 300

CGCTCGGGCT TTCTGAACAT TGACGAGTAC ATGCGCAGCT TCGCCGACCT GCGGCAGGGC 360

CTGGACCGCA GCGGGTCGAC GGCCGTGTGC GTGCTGCTCA GCCCGAGCCA CCTCTACTTC 420

ATTAACTGCG GCGACTCGCG GGCCGTGCTG AGTCGAGACG GCAAGGTGGG CTTCTCCACC 480

CAGGACCACA AGCCCTGCAA CCCCCGCGAG AAGGAGCGCA TCCAAAACGC CGGCGGCTCG 540

GTCATGATCC AGAGGGTAAA CGGCTCCTTG GCCGTGTCCC GGGCCCTTGG GGACTACGAC 600

TACAAATGTG TGGACGGTAA GGGCCCCACG GAGCAGCTGG TGAGCCCCGA GCCCGAGGTG 660

TGTGTGTTGG AGCGGGCGGC CGAAGGAGAC GAGTTCGTGG TGCTGGCGTG TGATGGAATC 720

TGGGACGTCA TGTCCAACGA GGAGCTGTGT GATTTTGTCC GCTCGCGGCT GCTGGTGTGC 780

GACGTCCTGG AGAAGGTGTG TAACGCGGTG GTGGACACCT GTCTGCATAA GGGGAGCAGG 840

GATAACATGA GTGTGGTGTT GGTGTGTTTA CCCGGAGCAC CGAAGATCTC AGAGGAGGCT 900

GTGAAGAAAG AAGAGGAATT GGATAAGTAC CTGGAGACCC GTGTGGAGGA GCTACTGGGG 960

AACTGTGGGG AGGCGGGAGT CCCTGACCTG GTGTCTGTCC TGAGGAGCAT TGCCACAGAG 1020

AACATCCCCA ACCTTCCACC TGGCGGAGGC CTGGCCAGCA AACGGAGCGT GATCGAAGCC 1080

GTGTACAACA AGCTGAATCC TCACAGAGAA GAGGAAGGGA GTGCCGGTGA GTTGGAAGAC 1140

CCCTGGTAG 1149

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++s++g+r emeda+t++   +  p     ++ff+vyDGh+gs+va++cs +l e++

Q: 23    RYGLSSMQGWRVEMEDAHTAA---VGLPHGLTDWSFFAVYDGHAGSRVANYCSGHLLEHI  79

         69****************974...444444445***********************9999

S: 62    aeele...sseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdskly  118

                 s+++  + vk+ ++++Fl++de ++ + + ++  d+sGstav++l+++s+ly

Q: 80    LSGGAdfsSGSGCVEGVKDGIRSGFLNIDEYMRSFADLRQGLDRSGSTAVCVLLSPSHLY  139

         876556768999999*********************************************

S: 119   vanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRal  178

         ++n+GdSravL+r+gk+   ++dHkp +++E+eRi++aggsv+ +   Rv+G+LavsRal

Q: 140   FINCGDSRAVLSRDGKVGFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSLAVSRAL  196

         *********************************************...************

S: 179   Gdlylk.........pyvtpePevtshrl.tsedefliLasDGlwdvvsneeavslvrdv  228

         Gd+++k         ++v+pePev + ++  + def++La+DG+wdv+snee++++vr++

Q: 197   GDYDYKcvdgkgpteQLVSPEPEVCVLERaAEGDEFVVLACDGIWDVMSNEELCDFVRSR  256

         *****************************667788*************************

S: 229   lekkeaeqeaakkLvklalargskdnvsaivv  260

         l   + ++++++ +v+++l++gs+dn+s+++v

Q: 257   LLVCDVLEKVCNAVVDTCLHKGSRDNMSVVLV  288

         ***************************99875

Domain Sequence
(FASTA)

RYGLSSMQGW RVEMEDAHTA AVGLPHGLTD WSFFAVYDGH AGSRVANYCS GHLLEHILSG 60

GADFSSGSGC VEGVKDGIRS GFLNIDEYMR SFADLRQGLD RSGSTAVCVL LSPSHLYFIN 120

CGDSRAVLSR DGKVGFSTQD HKPCNPREKE RIQNAGGSVM IQRVNGSLAV SRALGDYDYK 180

CVDGKGPTEQ LVSPEPEVCV LERAAEGDEF VVLACDGIWD VMSNEELCDF VRSRLLVCDV 240

LEKVCNAVVD TCLHKGSRDN MSVVLV 266

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Meleagris gallopavo"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Petromyzon marinus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013