EKS-GAA-00523

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00523

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	499.8	2.6E-150	30	287	258

Status

Unreviewed

Ensembl Protein

ENSGACP00000003852

UniProt Accession

G3NEX1;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000002922	ENSGACP00000003874	ENSGACT00000003888
ENSGACG00000002922	ENSGACP00000003870	ENSGACT00000003884
ENSGACG00000002922	ENSGACP00000003872	ENSGACT00000003886
ENSGACG00000002922	ENSGACP00000003863	ENSGACT00000003876
ENSGACG00000002922	ENSGACP00000003852	ENSGACT00000003865

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

364

Protein Sequence
(FASTA)

MHRRTRTTNS TSRNINLGPS GNPQAKPTDF DFLKVIGKGS FGKVFLAKLK HDEKYYAVKV 60

LQKKVILNRK EQKHIMAERN VLLKNVKHPF LVGLQYSFQT TDKLYFVLDF VNGGELFFHL 120

QKERTFPEPR AKFYIAEIAS ALGYLHSLNI VYRDLKPENI LLDHEGHIIL TDFGLCKEGI 180

SQTDTTTTFC GTPEYLAPEV LRKQPYDNTV DWWCLGSVLY EMLYGLPPFY SRDTHQMYDN 240

ILHKPLVMRP GASSTAWSLL QGLLEKEGMH RLGSMDDFNE IKAHSFFFSI NWDDLEQKKI 300

PPPFTPNVSS YCDISNFDPE FTEEMVPNSI CWSKDHSVVN ASVMEADDAF VGFSYAPASD 360

DFFL 364

Nucleotide Sequence
(FASTA)

ATGCATCGGA GGACGAGGAC GACAAACTCT ACCTCCAGAA ACATTAACCT GGGACCCTCT 60

GGAAATCCAC AGGCCAAGCC CACCGACTTT GACTTTTTGA AAGTCATAGG AAAGGGCAGT 120

TTTGGGAAGG TTTTCCTCGC CAAACTAAAA CATGATGAAA AGTATTATGC CGTCAAGGTT 180

TTACAGAAGA AGGTCATTCT CAACAGAAAG GAGCAAAAAC ACATCATGGC CGAGCGCAAC 240

GTGCTGCTGA AGAATGTGAA ACACCCTTTC CTAGTTGGGC TTCAGTATTC CTTCCAGACC 300

ACGGACAAGT TGTACTTCGT CTTGGATTTT GTCAATGGCG GAGAGCTTTT CTTCCATCTT 360

CAAAAAGAGC GGACCTTTCC GGAGCCCAGA GCAAAATTCT ACATTGCTGA GATCGCCAGT 420

GCACTGGGAT ATCTGCATTC TCTCAACATT GTTTACAGAG ACTTGAAGCC AGAAAACATC 480

CTCCTCGACC ACGAAGGGCA CATCATTCTG ACGGACTTCG GATTGTGCAA AGAGGGCATT 540

TCGCAGACCG ACACCACCAC CACTTTTTGT GGAACGCCGG AGTACTTGGC TCCAGAGGTC 600

CTGAGGAAGC AGCCGTATGA TAATACAGTG GACTGGTGGT GTCTGGGTTC AGTGCTGTAT 660

GAAATGCTTT ATGGACTGCC GCCGTTCTAC AGCAGGGACA CGCATCAAAT GTATGACAAC 720

ATCCTCCACA AGCCGCTGGT GATGCGTCCT GGTGCGTCCA GCACAGCCTG GTCTCTGCTC 780

CAGGGCCTGC TGGAGAAGGA GGGCATGCAC AGACTGGGGT CCATGGATGA CTTTAATGAG 840

ATCAAAGCAC ACAGCTTCTT CTTCTCCATC AACTGGGATG ATCTGGAACA GAAGAAGATC 900

CCTCCCCCAT TTACACCCAA TGTGAGCTCT TACTGTGACA TCTCTAACTT TGATCCGGAG 960

TTCACAGAGG AGATGGTCCC CAACTCCATC TGCTGGTCCA AAGACCATTC TGTAGTCAAC 1020

GCCAGTGTAA TGGAGGCCGA CGATGCCTTT GTGGGCTTCT CTTATGCCCC AGCTTCTGAT 1080

GACTTTTTCC TATGA 1095

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkv+lak k+dek+yavkvlqkk il++ke+khimaernvllknvkhp

Q: 30    FDFLKVIGKGSFGKVFLAKLKHDEKYYAVKVLQKKVILNRKEQKHIMAERNVLLKNVKHP  89

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt++klyfvld+vnggelffhlq+er+f+epra+fy aeiasalgylhsln

Q: 90    FLVGLQYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPEPRAKFYIAEIASALGYLHSLN  149

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenilld +gh++ltdfglcke+i + dtt+tfcgtpeylapevlrk+pyd+t

Q: 150   IVYRDLKPENILLDHEGHIILTDFGLCKEGISQTDTTTTFCGTPEYLAPEVLRKQPYDNT  209

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclg+vlyemlyglppfysrd+ +mydnil+kpl ++pg s +a++ll++llek+

Q: 210   VDWWCLGSVLYEMLYGLPPFYSRDTHQMYDNILHKPLVMRPGASSTAWSLLQGLLEKEGM  269

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg+ +df eik h ff

Q: 270   HRLGSMDDFNEIKAHSFF  287

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVFLAKL KHDEKYYAVK VLQKKVILNR KEQKHIMAER NVLLKNVKHP 60

FLVGLQYSFQ TTDKLYFVLD FVNGGELFFH LQKERTFPEP RAKFYIAEIA SALGYLHSLN 120

IVYRDLKPEN ILLDHEGHII LTDFGLCKEG ISQTDTTTTF CGTPEYLAPE VLRKQPYDNT 180

VDWWCLGSVL YEMLYGLPPF YSRDTHQMYD NILHKPLVMR PGASSTAWSL LQGLLEKEGM 240

HRLGSMDDFN EIKAHSFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013