EPS-GAA-00097

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAA-00097

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	253.7	1.7E-75	103	273	171

Status

Unreviewed

Ensembl Protein

ENSGACP00000005266

UniProt Accession

G3NIV6;

Protein Name

Protein Synonyms/Alias

Gene Name

TENC1 (1 of 2)

Gene Synonyms/Alias

TENC1 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000004001	ENSGACP00000005266	ENSGACT00000005281

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

1396

Protein Sequence
(FASTA)

KGEPHVFKEK TFKKKRQCSV CRQNVDNTGS FCRVCKTATH RKCEAKVTSA CIPPPSNDLC 60

MQQRRGTAPS RQIQHLGSTK SLTYTKQRNT LPRSFSVDRV MERVMERHYD FDLTYITERI 120

ISVFFPPKLE EQRYRLNLKE VAAMLKSKHQ DKFLLLNLSE RRHDINRLNA KVHDFGWPDL 180

HAPPLDKICA ICKAMETWLT SDPQHVVVLH CKGHKGKTGV IIAAYMHYSK ISAGADQALS 240

TLAMRKFCED KVSSSLQPSQ NRYIYYFGGL LSGAIKMNSS PLFLHQVLVP SLPNFQGEGG 300

YYPFLKIYQS MQLVYTSGIY DLQGTGGRRL CVTIEPALLL KGDIMVKCYH RRAQSADRDT 360

VFRLQFHTCT IHGSQLWFGK GELDEACTDE RFPSDATVEF VFSSGPEKIK GREYQKNDPS 420

VTVDYNTADP VVRWDSYENF NQRYQDSLEV DIAHTRGPVD GSLYAQIKKR RGPGSGSLTS 480

TNGSGPAAGL EEDRPDCVFS RGSDSALSAH SVHLNHSSVH PERQEDSISP LPPTRQERED 540

LARLLGGIEG NRDGERETAI LDDGDSLPSD RSGTLRLSRS CSCRNGYRSQ RCAEPGCDRT 600

LLMPNGYCLD RAPGTNGHHG ATPSPPDLVW DRQHYLHRSC SEAHHHLHPH HSKPSTSPTY 660

HDIVLMDGLP APGCPCRDCS IRKDDSAAYH SLRLDQGSEL HWEREPGLRR GREMSLHWER 720

DREAELQWER DREAEYWRRR ATVASYGPQG HDLPAFTFDP LPSGHPAYPE ASRSHAHSHM 780

EQKYSSSSSG YQTPRQVCPC SPYQPSPSES RGYASGYQSE STSPLPPASS MTGPCSHGLR 840

SSGESVGWRE HITHGSFKRV HRDGHAACST PSDMSGPSTP VHTSSPLRTQ PQSRREDPSA 900

PTAQAPPSFD PATASASSQG LGRALSSPIH TLSSLDTPSQ PAPLAPQAPH PSEAAALPST 960

VAQAVPRPQG HTQTQGAGTT RPAQVTGPPS EAEKLTITPT NATSAPASPT PASSSTAQAA 1020

CSSTESSPVS DTPVPGFATL GRRLMPLPEK RHPPVQPGFP SDGAATLRPA GGHAPPSSSQ 1080

HQLHVTFSPT VGEIAAPAGQ NDGSPPVESE NANRVSVKFV QDSSRFWYKP GISREQAIAA 1140

LKEREPGTFL IRDSNSFQGA YGLALKVATP PSNVNHSMSD PLEQLVRHFL LETGPRGVKI 1200

KGCQNEPYFG SLSALVYQHA ITPISLPCAL KITEKDLIGE VPEVQPVNNI STAADLLKQG 1260

AACNVLYLNS VETESLTGPQ AIAKGTDASL GRSPRPAGTV VQFKVTSQGI TLTDSQRRVF 1320

FRRHYPVSSV TFSSIDPKDR RWTNSDSTAN KVFGFVAKKP GSSSENVCHL FAELDPEQPA 1380

SAIVNFINKV MLSQRR 1396

Nucleotide Sequence
(FASTA)

AAGGGAGAGC CCCACGTCTT TAAGGAAAAA ACCTTCAAGA AAAAGCGCCA GTGCAGCGTG 60

TGCCGCCAGA ACGTGGACAA CACCGGCTCT TTCTGCAGAG TATGCAAGAC AGCCACCCAC 120

AGGAAGTGTG AGGCAAAGGT GACCTCGGCG TGCATCCCGC CCCCTTCCAA TGATCTGTGC 180

ATGCAGCAGC GCAGAGGGAC CGCCCCGTCC CGACAAATCC AGCACCTGGG GTCCACCAAG 240

TCGCTGACCT ATACCAAACA GAGGAACACT TTGCCACGGA GCTTCAGCGT GGACCGCGTG 300

ATGGAGAGAG TGATGGAGCG CCACTACGAC TTCGATCTGA CCTACATCAC CGAGAGGATC 360

ATCTCCGTGT TCTTCCCCCC GAAGCTTGAG GAGCAGAGGT ACCGCCTCAA CCTGAAGGAG 420

GTGGCTGCCA TGCTAAAGTC CAAACACCAG GACAAGTTCC TGCTCCTGAA CCTCTCCGAG 480

AGGCGCCACG ATATCAACCG GCTGAATGCA AAGGTCCACG ACTTTGGCTG GCCCGACCTC 540

CACGCCCCAC CGCTGGACAA GATCTGTGCC ATCTGCAAGG CCATGGAGAC GTGGCTGACC 600

TCCGACCCCC AGCACGTGGT GGTCCTGCAC TGCAAGGGCC ACAAAGGTAA AACGGGCGTG 660

ATTATTGCAG CCTACATGCA CTACAGCAAG ATCTCTGCAG GGGCGGACCA GGCTCTCAGT 720

ACTTTGGCCA TGAGGAAGTT CTGTGAAGAT AAGGTGTCCT CTTCCCTCCA GCCGTCCCAA 780

AACAGGTATA TCTATTACTT CGGGGGCCTT CTGTCCGGGG CGATCAAGAT GAACAGCAGC 840

CCCCTCTTCC TCCACCAAGT TCTGGTCCCA TCACTCCCAA ACTTCCAGGG CGAAGGAGGT 900

TACTACCCAT TCCTGAAGAT CTACCAGTCC ATGCAGCTGG TCTACACTTC AGGCATATAT 960

GACCTTCAGG GCACCGGAGG CAGGCGGCTG TGTGTGACCA TCGAGCCGGC GCTGCTGCTA 1020

AAGGGTGACA TCATGGTCAA ATGCTACCAC CGCCGAGCCC AGAGCGCTGA CCGAGACACC 1080

GTGTTCAGGT TGCAGTTTCA CACCTGCACC ATCCACGGGT CCCAGCTGTG GTTCGGCAAA 1140

GGGGAGCTGG ACGAAGCATG TACCGATGAG CGTTTTCCGT CTGATGCCAC AGTTGAGTTT 1200

GTCTTCTCCT CTGGACCTGA AAAAATCAAA GGCCGCGAGT ACCAGAAGAA CGACCCATCT 1260

GTCACAGTCG ACTACAACAC CGCTGACCCT GTGGTGCGCT GGGACTCCTA CGAGAACTTT 1320

AACCAGCGAT ACCAGGACAG CCTGGAGGTA GATATTGCCC ACACCAGAGG GCCCGTGGAC 1380

GGCAGCCTCT ACGCTCAGAT AAAGAAGCGC CGAGGTCCCG GCTCCGGTTC TCTCACCTCA 1440

ACCAACGGCA GCGGCCCGGC GGCGGGCCTT GAGGAAGACA GGCCAGATTG CGTCTTCTCT 1500

CGCGGTTCAG ACTCCGCCCT CTCGGCCCAC TCCGTCCATT TGAACCATTC ATCCGTCCAT 1560

CCAGAGCGCC AGGAGGATTC CATCAGCCCG CTGCCTCCGA CCAGGCAGGA GAGAGAAGAC 1620

CTGGCGCGTC TTCTCGGAGG CATCGAGGGA AACCGCGATG GGGAGCGAGA GACGGCCATC 1680

TTGGATGACG GCGATTCTTT GCCCTCTGAC AGAAGCGGGA CGCTGAGGCT CAGCCGGTCC 1740

TGCTCCTGCC GGAATGGGTA CCGGTCACAG CGGTGCGCCG AGCCCGGCTG CGACCGCACC 1800

CTCCTTATGC CCAACGGGTA CTGCCTCGAC CGGGCCCCCG GCACCAACGG CCACCACGGG 1860

GCGACGCCTT CTCCTCCGGA TCTGGTGTGG GACCGCCAGC ACTACCTGCA CCGCTCCTGC 1920

TCGGAGGCCC ACCACCATCT CCACCCGCAC CACTCCAAAC CCTCCACCAG CCCTACCTAC 1980

CACGATATAG TGCTAATGGA TGGCCTACCC GCCCCTGGCT GCCCTTGCAG AGACTGCAGC 2040

ATCAGGAAAG ACGACTCGGC GGCCTATCAC AGCCTGAGGC TGGACCAAGG GTCAGAGCTC 2100

CACTGGGAGA GGGAACCTGG GCTGAGACGA GGCAGAGAGA TGTCCCTCCA CTGGGAGAGG 2160

GACCGGGAGG CGGAGCTGCA GTGGGAGCGG GACAGAGAGG CGGAGTACTG GCGCAGGAGG 2220

GCCACCGTGG CCTCTTACGG CCCACAGGGC CACGATCTCC CGGCCTTCAC GTTTGACCCC 2280

TTGCCATCGG GTCACCCGGC TTATCCAGAG GCGTCGAGGT CCCACGCTCA TTCCCACATG 2340

GAGCAGAAGT ACAGCAGCAG CAGCAGCGGT TACCAAACGC CTCGACAGGT GTGCCCCTGC 2400

TCGCCGTACC AGCCCTCGCC GTCTGAAAGC AGGGGCTACG CTTCGGGCTA CCAGTCCGAG 2460

TCCACGTCCC CGCTGCCCCC GGCTTCCTCC ATGACGGGGC CCTGCAGCCA CGGCCTCAGG 2520

AGCTCTGGAG AAAGTGTGGG CTGGAGGGAG CACATCACCC ACGGTTCCTT TAAGAGGGTC 2580

CACAGAGACG GCCACGCCGC ATGCTCCACG CCATCCGATA TGTCTGGACC GTCCACCCCT 2640

GTCCACACCA GCAGCCCCCT GCGCACACAG CCCCAGTCCA GGAGGGAGGA CCCAAGCGCT 2700

CCGACAGCGC AGGCCCCGCC TTCTTTTGAT CCTGCAACGG CGAGCGCATC AAGCCAGGGG 2760

CTCGGCCGGG CTCTCTCGTC CCCGATCCAC ACTTTGTCGT CGCTGGACAC CCCCTCCCAA 2820

CCTGCCCCTC TCGCTCCGCA GGCCCCCCAT CCCTCAGAGG CTGCTGCTCT GCCTTCCACT 2880

GTGGCACAGG CCGTTCCCCG GCCTCAGGGC CACACTCAAA CCCAAGGCGC CGGAACCACA 2940

AGACCAGCAC AAGTCACCGG ACCACCCTCG GAAGCCGAAA AACTTACAAT AACCCCCACC 3000

AACGCCACGT CTGCCCCCGC ATCTCCCACC CCAGCCTCAT CTTCAACCGC CCAGGCGGCC 3060

TGCAGTAGTA CGGAGAGCTC CCCGGTCTCC GACACCCCGG TTCCCGGCTT TGCCACTTTG 3120

GGCAGGAGGC TGATGCCGCT GCCAGAGAAG CGCCACCCGC CGGTCCAGCC GGGCTTCCCC 3180

AGCGATGGGG CGGCTACCCT GAGGCCGGCC GGGGGCCACG CGCCTCCCTC CAGCAGCCAG 3240

CATCAGCTCC ACGTCACCTT CTCTCCCACC GTGGGGGAAA TCGCCGCCCC CGCAGGCCAA 3300

AACGACGGAT CGCCGCCTGT TGAGAGCGAG AACGCAAATA GGGTCAGCGT GAAGTTCGTC 3360

CAGGACAGTT CACGCTTCTG GTACAAGCCT GGAATCTCCA GGGAGCAAGC AATCGCTGCC 3420

CTGAAGGAGA GAGAGCCGGG GACCTTCCTG ATCAGGGACA GTAACTCTTT CCAGGGGGCC 3480

TACGGCCTCG CCCTGAAGGT GGCCACACCC CCTTCCAATG TCAACCACAG CATGAGCGAC 3540

CCTCTGGAAC AGCTGGTCAG ACACTTCCTG TTAGAAACCG GCCCCCGAGG AGTCAAGATC 3600

AAAGGGTGCC AGAATGAGCC CTACTTTGGG AGTCTGTCTG CATTGGTCTA CCAACACGCC 3660

ATCACACCCA TCTCTCTGCC CTGCGCCCTC AAGATCACAG AGAAAGATCT GATAGGAGAA 3720

GTGCCAGAGG TTCAGCCTGT GAATAACATC AGCACGGCTG CTGACCTGCT GAAACAAGGA 3780

GCAGCCTGTA ACGTCCTCTA CCTGAACTCG GTGGAAACCG AGTCTCTAAC CGGCCCCCAG 3840

GCCATCGCCA AGGGGACAGA CGCGTCCTTG GGTCGTAGCC CCCGTCCCGC TGGCACTGTG 3900

GTCCAGTTTA AGGTGACGTC GCAGGGCATC ACGCTGACCG ACAGCCAGCG CAGGGTTTTC 3960

TTTAGGAGAC ATTACCCAGT GAGCAGCGTG ACCTTCAGCA GCATTGACCC TAAGGACAGG 4020

AGGTGGACTA ATTCAGACAG CACCGCTAAT AAAGTGTTCG GTTTCGTGGC CAAGAAGCCG 4080

GGCAGCTCGT CCGAGAACGT CTGCCACCTG TTTGCTGAGC TGGACCCCGA GCAGCCGGCC 4140

TCCGCCATCG TCAACTTCAT CAACAAGGTC ATGTTGTCGC AGCGGCGGTA G 4191

Domain Profile

S: 2     rltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcser  61

         r++e+ +d+dlty+terii+v fP + +e++yr nl+ev+ +l+skh++k++l nl ser

Q: 103   RVMERHYDFDLTYITERIISVFFPPKLEEQRYRLNLKEVAAMLKSKHQDKFLLLNL-SER  161

         89******************************************************.***

S: 62    rydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvi  121

         r+d+++lnakv++fg++dl+aP+l+k+++ick++++Wl+ d+++vvvlhckg kg++Gvi

Q: 162   RHDINRLNAKVHDFGWPDLHAPPLDKICAICKAMETWLTSDPQHVVVLHCKGHKGKTGVI  221

         ************************************************************

S: 122   vcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         ++ay+++s+isa+ad+al t+++r+++edkv++  qPsq+ry++yf +ll+g

Q: 222   IAAYMHYSKISAGADQALSTLAMRKFCEDKVSSSLQPSQNRYIYYFGGLLSG  273

         *************************************************986

Domain Sequence
(FASTA)

RVMERHYDFD LTYITERIIS VFFPPKLEEQ RYRLNLKEVA AMLKSKHQDK FLLLNLSERR 60

HDINRLNAKV HDFGWPDLHA PPLDKICAIC KAMETWLTSD PQHVVVLHCK GHKGKTGVII 120

AAYMHYSKIS AGADQALSTL AMRKFCEDKV SSSLQPSQNR YIYYFGGLLS G 171

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0046872	; F:metal ion binding
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00130	; C1_1; 1.
PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00109	; C1; 1.
SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 1.

Prints

Created Date

20-Feb-2013