EKS-GAA-00299

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00299

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	358.3	2.6E-107	55	303	249

Status

Unreviewed

Ensembl Protein

ENSGACP00000006267

UniProt Accession

G3NLP6;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK3

Gene Synonyms/Alias

MARK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000004742	ENSGACP00000006267	ENSGACT00000006284
ENSGACG00000004742	ENSGACP00000006259	ENSGACT00000006276

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

723

Protein Sequence
(FASTA)

EMSTKTPLPT VNEKVTESHT SHSNGRQEVS VRSARTGVRS RGSEEPQQPH VGKLLLKTIG 60

KGNFAKVKLR HILTGREVSA HSLDRDEMTP LSLSELFREV RIMKILNHPN IVKLFEVIET 120

ERTLYLVMEY ASGGEVFDYL VAHGRMKEKE ARSKFRQIVS AVQYCHQKHI VHRDLKAENL 180

LLDADMNIKI ADFGFSNEFT MGNKLDTFCG SPPYAAPELF QGKKYDGPEV DVWSLGVILY 240

TLVSGSLPFD GQNLKELRER VLRGKYRIPF YMSTDCENLL KRFLVLNPSK RGTLEQIMKD 300

RWINAGFEED ELKPYIEPEL DITDQKRIDV MVGMGYNLEE IQESLAKMKY DEITASYLLL 360

GRKASEMEPS ESASSSNLSL AKARPSSELN GQSPSHLKVQ RSVSSNHKQR RYSEQVGQNV 420

PPGMSHPKRS PTTTAENSAK EEGGVQMRKP SAPPASPLLG NANNPNKADI PDRRKGATTG 480

PSSNAAAAAA MTRRNTYVCS DRNNGDRLSV IPNGKENSSV AASPGGQRNP VASINSIANA 540

STPDRLRFPR GTASRSTFHG GQLRDRRTAT YNGPPASPTL SHDATPLSQT RSRGTSNLFS 600

KLTSKLTRSR HVPGDQKGEN KDGKPRALRF TWSMRTTSSM EPCDIMREIR KVLDANNCDY 660

EQQESFLLLC VHGDGRAENL VQWEMEVCKL PRLSLNGVRF KRISGSSIAF KNIASKVANE 720

LKL 723

Nucleotide Sequence
(FASTA)

GAGATGTCAA CAAAAACTCC TCTGCCAACG GTCAACGAGA AGGTGACGGA GAGTCACACC 60

TCTCACAGCA ATGGGCGCCA GGAGGTCAGC GTGCGCTCGG CCCGGACCGG CGTCCGATCC 120

CGCGGCTCCG AGGAGCCGCA GCAGCCACAC GTGGGGAAAC TACTGCTCAA AACCATCGGC 180

AAGGGCAACT TCGCCAAGGT GAAGCTGCGA CACATCCTGA CCGGCAGAGA GGTGTCCGCT 240

CACTCTCTCG ATCGAGATGA GATGACCCCC CTCTCGCTCT CTGAGCTCTT TCGAGAAGTC 300

CGTATCATGA AGATATTGAA CCACCCAAAT ATCGTCAAGC TCTTCGAGGT GATCGAGACT 360

GAGCGGACGC TCTACCTGGT GATGGAGTAC GCGAGCGGAG GGGAGGTGTT TGACTACCTG 420

GTCGCACATG GACGAATGAA GGAGAAAGAG GCCAGGTCTA AATTTAGACA GATCGTATCG 480

GCGGTGCAGT ACTGCCACCA GAAGCACATC GTTCACAGAG ACCTCAAGGC GGAGAACCTG 540

CTCCTCGACG CCGACATGAA CATCAAGATC GCCGACTTCG GCTTCAGCAA CGAGTTCACG 600

ATGGGCAACA AGCTGGACAC GTTCTGCGGG TCGCCGCCCT ACGCCGCGCC CGAGCTCTTC 660

CAGGGGAAGA AGTACGACGG GCCCGAGGTG GACGTGTGGA GCCTCGGGGT CATCCTGTAC 720

ACGCTGGTCA GCGGCTCGCT GCCCTTCGAC GGCCAGAACC TGAAGGAGCT GCGTGAGCGC 780

GTGCTGCGCG GGAAGTACCG CATCCCCTTC TACATGTCCA CGGACTGCGA GAACCTCCTC 840

AAACGCTTCC TGGTGCTCAA CCCGTCCAAG CGGGGGACGC TCGAGCAAAT CATGAAGGAT 900

CGATGGATCA ACGCCGGCTT TGAAGAAGAC GAGCTGAAGC CGTACATCGA GCCGGAGCTG 960

GACATCACGG ATCAGAAGAG AATCGATGTG ATGGTCGGGA TGGGCTACAA CCTGGAGGAG 1020

ATCCAGGAGT CTTTGGCCAA GATGAAGTAT GACGAGATCA CAGCCTCCTA CCTGCTGCTG 1080

GGCCGCAAGG CCTCCGAGAT GGAGCCCAGC GAGTCGGCCT CCAGCAGCAA CTTGTCTCTG 1140

GCCAAAGCGC GGCCGAGCAG CGAGCTCAAC GGACAGTCGC CCTCCCACCT CAAGGTGCAA 1200

CGCAGCGTCT CCTCCAACCA CAAGCAGAGG CGCTACAGCG AGCAGGTCGG TCAGAACGTC 1260

CCTCCTGGGA TGTCCCACCC AAAGAGGAGT CCGACCACCA CAGCGGAGAA CAGCGCCAAG 1320

GAGGAAGGCG GAGTCCAAAT GCGTAAACCC AGCGCTCCGC CCGCCTCCCC CCTGCTGGGC 1380

AACGCCAACA ACCCCAACAA GGCCGACATC CCCGACCGCA GGAAAGGCGC CACCACCGGG 1440

CCGAGCAGCA ACGCGGCGGC GGCGGCGGCG ATGACCCGGA GGAACACGTA CGTCTGCAGC 1500

GACCGGAACA ATGGCGACCG GCTGTCCGTC ATCCCCAACG GGAAGGAGAA CAGCAGCGTC 1560

GCAGCGTCGC CCGGCGGGCA GAGGAACCCG GTGGCGTCGA TCAACAGCAT CGCCAACGCC 1620

TCCACCCCCG ACCGCCTGCG CTTCCCGCGC GGCACCGCCA GCCGCAGCAC CTTCCACGGC 1680

GGCCAGCTGA GGGACCGCCG CACGGCCACC TACAACGGGC CCCCCGCCTC GCCCACGCTG 1740

TCCCACGACG CCACGCCCCT CTCCCAGACC CGCAGCCGTG GAACCAGCAA CCTCTTCTCC 1800

AAGCTCACCT CCAAGCTCAC CCGCAGTCGC CATGTACCTG GGGATCAAAA AGGGGAAAAC 1860

AAAGACGGTA AACCCCGCGC CCTCCGATTC ACTTGGAGTA TGAGGACCAC CAGCTCCATG 1920

GAGCCCTGTG ACATCATGCG GGAGATTCGC AAGGTGCTCG ACGCCAACAA CTGCGACTAC 1980

GAGCAGCAAG AGAGTTTCCT GCTGCTGTGC GTGCACGGGG ACGGGCGGGC GGAGAACCTG 2040

GTGCAGTGGG AGATGGAGGT CTGCAAGCTG CCGCGCCTCT CGCTCAACGG CGTCCGCTTC 2100

AAACGGATAT CCGGATCATC CATCGCTTTC AAAAACATTG CTTCCAAAGT TGCCAATGAG 2160

TTAAAGCTAT GA 2172

Domain Profile

S: 3     llktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpniik  62

         llkt+G+g+f+kVkl +h +t+++v    +++++++  sl++++rE++i+k+l+hpni+k

Q: 55    LLKTIGKGNFAKVKL-RHILTGREVSAHSLDRDEMTPLSLSELFREVRIMKILNHPNIVK  113

         689**********98.799*****************************************

S: 63    llevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHr  122

         l+eviet+++lylv+eyasgge+fdy++++gr+kekear+ f+q+vsav+Y+h+k+ivHr

Q: 114   LFEVIETERTLYLVMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKHIVHR  173

         ************************************************************

S: 123   DlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvDvW  182

         DlK+eNllld+++nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vDvW

Q: 174   DLKAENLLLDADMNIKIADFGFSNEFTMGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW  233

         ************************************************************

S: 183   slGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekRat  242

         slGv+Ly+lv+g+lPfd++nlkel+e++l+gk++ip+++s+++e+Ll+++Lv +p+kR t

Q: 234   SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPSKRGT  293

         ************************************************************

S: 243   ieeilkhewl  252

         +e+i+k++w+

Q: 294   LEQIMKDRWI  303

         *********7

Domain Sequence
(FASTA)

LLKTIGKGNF AKVKLRHILT GREVSAHSLD RDEMTPLSLS ELFREVRIMK ILNHPNIVKL 60

FEVIETERTL YLVMEYASGG EVFDYLVAHG RMKEKEARSK FRQIVSAVQY CHQKHIVHRD 120

LKAENLLLDA DMNIKIADFG FSNEFTMGNK LDTFCGSPPY AAPELFQGKK YDGPEVDVWS 180

LGVILYTLVS GSLPFDGQNL KELRERVLRG KYRIPFYMST DCENLLKRFL VLNPSKRGTL 240

EQIMKDRWI 249

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF02149	; KA1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS50032	; KA1; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013