EKS-GAA-00250

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00250

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	286.4	3.0E-85	26	243	218

Status

Unreviewed

Ensembl Protein

ENSGACP00000006718

UniProt Accession

G3NN05;

Protein Name

Protein Synonyms/Alias

Gene Name

MASTL

Gene Synonyms/Alias

MASTL;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000005087	ENSGACP00000006722	ENSGACT00000006739
ENSGACG00000005087	ENSGACP00000006718	ENSGACT00000006735

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

842

Protein Sequence
(FASTA)

MDADEKQDSG GNKSLEIARA PSIEDFIVLK PISRGAFGKV YLARKKCNEQ LYAIKVMKKA 60

DMVDKNMTGQ MKAERDALAL SKSPFVVHLF YSLQTATKIY LLMEYLIGGD VKSLLHIYGY 120

FDQDMSVKYI SEVALALDYL HRHGIIHRDL KPDNMLISNK GHIKLTDFGL SKVKLDHELS 180

LVDILTTPSL AKPRQDYSRT PGQVLSLIST IGFNSPTGES KRHSSASAVS SPMSCGKIKP 240

RSSSFASPMM KKKDSPYSPL PWKTGPKNMM FSPHCLAKNL TPSLLKTRKR FETMSAGSTD 300

TECGISPLWE CEERCPDQLI HLQILIQVIP FYYKENEHAN EQKGRRHSES RWPEQESAKM 360

AAFGFSDRAA GALSEDHRAG KRPPANQLEP LSTSPDVVGL SASSLKRKFC EVERSPEPRD 420

SQAKKSNEAY KRCCAVPEET ARSHTGLTGT FCTIRIDDFL ASSKGIGIPK RSSPIACTKS 480

LFGELEEPPQ DVFDDGAKDL SGLGSTSPLD GNRDICRSLS LDSDGSVHET SLTIDSRAPF 540

GSRKRSKGNN SAAAEPEGNN NSFITGSLPQ TPSQTPKPGN FGRRGSQCSA LNLHDDFAGV 600

GQSPSFLKPR NIVAFRSYCS SINRSNASGV SRFSVGSIEA MDFSNAASHH SASGIVTPVQ 660

RRLRSNGSSY QTPQPMSTSH TPFRTPKSVR RGALPVEGAQ ILGTPDYLAP ELLLGKPHDC 720

MVDWWALGVC LFEFLTGVPP FNDETPQLVF HNILNKDIPW PEEEEELCVN SRNAIEILLT 780

VDTRKRAGLK ELKCHPLFEG LDWDDLQNQP MPFIPQPEDE TDTSYFDARN SAQHIDVSGF 840

SL 842

Nucleotide Sequence
(FASTA)

ATGGACGCGG ATGAGAAGCA GGACTCCGGT GGAAATAAGT CGTTGGAAAT CGCGAGGGCT 60

CCTTCCATCG AGGATTTCAT CGTTTTGAAG CCCATCAGCC GCGGTGCCTT TGGCAAAGTC 120

TACCTCGCAC GGAAGAAGTG CAATGAGCAA TTATACGCCA TCAAGGTGAT GAAGAAAGCC 180

GACATGGTTG ACAAAAACAT GACCGGTCAG ATGAAGGCAG AGAGAGACGC CCTCGCTTTG 240

AGCAAAAGCC CCTTTGTGGT TCACCTGTTT TACTCCCTGC AGACTGCAAC CAAGATCTAT 300

CTGTTAATGG AATACCTCAT TGGTGGAGAT GTCAAATCTC TGCTTCACAT CTATGGCTAT 360

TTCGACCAGG ACATGTCTGT AAAATATATT TCCGAGGTTG CACTGGCTTT GGACTACCTC 420

CACCGCCACG GTATAATCCA CAGGGACTTG AAGCCAGATA ACATGCTTAT ATCCAACAAA 480

GGTCACATCA AACTGACAGA CTTTGGCCTC TCTAAAGTCA AGCTTGACCA TGAGCTCAGT 540

CTTGTGGATA TCCTCACTAC TCCATCTTTG GCGAAACCCA GACAAGATTA CTCCCGCACA 600

CCGGGTCAAG TCCTCTCCCT AATCAGCACC ATTGGATTTA ATTCACCTAC AGGAGAAAGC 660

AAGCGTCACA GCAGCGCATC CGCTGTGTCC AGTCCCATGT CCTGTGGCAA AATAAAACCG 720

AGGAGTAGCT CTTTCGCTTC TCCTATGATG AAGAAAAAAG ATAGTCCGTA CTCTCCGCTT 780

CCTTGGAAAA CCGGACCCAA AAACATGATG TTCAGCCCTC ACTGCCTGGC TAAGAATCTG 840

ACCCCCTCAC TGCTGAAGAC CAGGAAGAGG TTTGAGACGA TGAGTGCAGG GAGCACCGAC 900

ACCGAATGCG GCATCAGTCC ACTGTGGGAG TGCGAGGAGC GTTGTCCTGA CCAACTTATT 960

CACCTCCAAA TCTTAATTCA AGTCATTCCA TTTTATTACA AAGAAAACGA ACATGCTAAT 1020

GAACAAAAGG GGAGACGACA TTCTGAGTCC AGGTGGCCTG AGCAGGAGTC CGCAAAGATG 1080

GCCGCCTTTG GCTTCTCTGA CAGGGCCGCC GGCGCTCTGT CAGAAGACCA CCGCGCGGGA 1140

AAGAGGCCTC CCGCAAACCA GCTGGAGCCG CTTTCCACAT CTCCGGACGT GGTTGGTCTC 1200

TCGGCCTCGT CGTTGAAGAG AAAATTCTGT GAGGTCGAGA GAAGCCCCGA GCCGCGGGAC 1260

AGCCAAGCCA AGAAGAGCAA CGAGGCCTAC AAGAGGTGCT GCGCGGTCCC AGAGGAGACG 1320

GCGAGGTCCC ACACCGGCCT GACTGGAACG TTCTGCACCA TCCGGATAGA CGACTTCCTG 1380

GCCTCCTCGA AGGGGATCGG GATCCCGAAG CGCTCCAGCC CCATCGCCTG CACCAAGAGC 1440

CTTTTCGGCG AGCTGGAGGA GCCGCCGCAG GACGTGTTCG ACGACGGCGC CAAAGACCTG 1500

TCCGGCTTAG GCTCCACGTC GCCACTCGAC GGGAACCGCG ACATTTGCAG GAGCTTGAGC 1560

CTCGACTCTG ACGGCTCGGT GCACGAAACG TCTCTCACCA TCGACAGCCG CGCCCCTTTC 1620

GGGTCGCGCA AGCGTTCCAA AGGGAACAAC TCCGCCGCGG CGGAGCCCGA GGGGAATAAC 1680

AACTCGTTCA TCACCGGGTC GCTCCCACAA ACTCCGTCCC AAACACCCAA ACCGGGTAAC 1740

TTTGGCCGGC GGGGATCTCA GTGCTCCGCT CTGAACCTGC ACGATGACTT CGCCGGGGTC 1800

GGACAGTCGC CCTCGTTCCT CAAGCCGCGT AACATCGTGG CCTTCCGAAG CTACTGCAGC 1860

TCCATCAACC GCTCCAACGC GTCCGGCGTG TCCCGGTTCA GCGTCGGCTC CATCGAGGCC 1920

ATGGACTTCT CCAACGCGGC CTCCCACCAC TCCGCCTCCG GCATCGTGAC GCCGGTGCAG 1980

AGAAGGCTGC GATCCAACGG CTCAAGCTAT CAGACTCCTC AGCCCATGTC GACCTCTCAC 2040

ACCCCCTTCA GGACCCCAAA GAGCGTCAGG AGGGGCGCGC TGCCCGTCGA AGGCGCACAA 2100

ATCTTAGGAA CTCCGGACTA TTTGGCTCCG GAGCTTCTCT TGGGAAAACC GCACGACTGC 2160

ATGGTGGATT GGTGGGCGCT TGGTGTGTGT CTTTTTGAGT TCCTCACAGG CGTGCCGCCG 2220

TTCAACGACG AGACCCCTCA GCTGGTCTTT CACAATATTC TCAACAAAGA TATTCCCTGG 2280

CCCGAGGAAG AGGAGGAACT GTGTGTGAAC TCAAGAAATG CGATTGAAAT TCTTCTGACC 2340

GTAGACACGA GAAAACGAGC TGGTCTGAAG GAACTCAAGT GCCACCCCCT GTTCGAGGGC 2400

TTGGACTGGG ACGACCTGCA GAACCAGCCG ATGCCTTTCA TTCCTCAGCC AGAGGACGAA 2460

ACCGACACTT CGTACTTTGA CGCGAGAAAC AGCGCTCAGC ACATCGACGT GTCCGGCTTC 2520

AGTCTGTAG 2529

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         f ++k+isrGa+G+vyl r+k  ++++a+k++kk+d++ kn++ q+ aerd+lal+++pf

Q: 26    FIVLKPISRGAFGKVYLARKKCNEQLYAIKVMKKADMVDKNMTGQMKAERDALALSKSPF  85

         6789********************************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         vv+l+ysl+t+ ++yl+mey++GGdvksll+++G++d++m+++yi+ev+lal+ylhr+Gi

Q: 86    VVHLFYSLQTATKIYLLMEYLIGGDVKSLLHIYGYFDQDMSVKYISEVALALDYLHRHGI  145

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         +hrdlkPdn+li+++GhikltdfGlskv+l            ++   ++l     +tP++

Q: 146   IHRDLKPDNMLISNKGHIKLTDFGLSKVKLD----------HELSLVDIL-----TTPSL  190

         ******************************9..........677777777.....*****

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqvlsdeivwPekd  237

         ++P    rq+y++++++++++i+  +f+ +  + +  ++ +  ++ +s + + P +

Q: 191   AKP----RQDYSRTPGQVLSLISTIGFNSPTGESKRHSSASAVSSPMSCGKIKPRSS  243

         ***....*************************9999888887777777776666554

Domain Sequence
(FASTA)

FIVLKPISRG AFGKVYLARK KCNEQLYAIK VMKKADMVDK NMTGQMKAER DALALSKSPF 60

VVHLFYSLQT ATKIYLLMEY LIGGDVKSLL HIYGYFDQDM SVKYISEVAL ALDYLHRHGI 120

IHRDLKPDNM LISNKGHIKL TDFGLSKVKL DHELSLVDIL TTPSLAKPRQ DYSRTPGQVL 180

SLISTIGFNS PTGESKRHSS ASAVSSPMSC GKIKPRSS 218

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>