EKS-GAA-00091

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00091

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	331.7	4.7E-99	26	335	310

Status

Unreviewed

Ensembl Protein

ENSGACP00000008759

UniProt Accession

G3NTU1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK19

Gene Synonyms/Alias

CDK19;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000006602	ENSGACP00000008759	ENSGACT00000008778
ENSGACG00000006602	ENSGACP00000008763	ENSGACT00000008782
ENSGACG00000006602	ENSGACP00000008766	ENSGACT00000008785

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

493

Protein Sequence
(FASTA)

MDYDFKTKLA AEREKVEDLF EYEGCKVGRG TYGHVYKAKR KDGKDEKEYA LKQIEGTGIS 60

MSACREVALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF HRASKGNKKP 120

TQLPRGMVKS LLYQILDGIH YLHANWVLHR DLKPANILVM GEGPERGRVK IADMGFARLF 180

NSPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED 240

IKTSNPFHHD QLDRIFSVMG FPADKDWEDI RKMPEYPTLQ KDFRRTTYAT SSLIKYMEKH 300

KVKPESKVFL LLQKLLTMDP TKRITSEHSL QDPYFLEEPL PTTDVFAGCQ IPYPKREFLN 360

EDEPEEKTEK NQTQPHQQTT GQTQAQNQQQ TAPQQAPSLQ NLAQTNGNAG ATGAATGGGL 420

QHGQDQGPHN KKPRIGPSGA SSGTGLLQSE YQLSGSRLGY QSSIQGSTQP QGTMGYSSSS 480

QQSSHYSHQT HRY 493

Nucleotide Sequence
(FASTA)

ATGGATTACG ACTTCAAAAC AAAGCTGGCG GCCGAGAGAG AGAAGGTGGA AGATCTGTTC 60

GAATATGAAG GTTGCAAAGT GGGTCGAGGC ACCTACGGGC ACGTATATAA AGCTAAGCGA 120

AAAGACGGGA AAGATGAAAA GGAGTACGCA CTGAAACAAA TAGAAGGCAC CGGAATATCG 180

ATGTCTGCCT GTAGGGAAGT CGCTCTTTTA CGAGAACTGA AACATCCGAA TGTGATCGCC 240

CTGCAGAAAG TGTTCCTGTC CCACAGCGAC AGAAAGGTTT GGCTCCTCTT CGACTATGCC 300

GAGCACGACC TATGGCACAT CATCAAGTTC CACCGCGCCT CCAAGGGCAA CAAGAAACCC 360

ACACAGCTGC CCCGCGGGAT GGTGAAGTCT CTCCTGTATC AGATTCTGGA TGGGATTCAT 420

TACCTCCATG CCAACTGGGT GCTGCACAGG GATTTGAAAC CGGCTAACAT CCTGGTGATG 480

GGGGAAGGTC CAGAGCGGGG ACGAGTTAAA ATCGCCGACA TGGGTTTTGC CAGACTCTTC 540

AACTCTCCCC TCAAGCCGCT GGCGGACCTC GACCCCGTAG TGGTGACCTT CTGGTACAGG 600

GCCCCCGAGC TTCTGCTGGG GGCCCGGCAC TACACCAAGG CTATCGATAT TTGGGCAATT 660

GGCTGCATCT TTGCGGAGCT GCTAACATCC GAGCCCATCT TTCACTGTCG CCAGGAAGAC 720

ATCAAAACCA GTAATCCCTT CCATCATGAC CAGCTGGACC GGATATTCAG CGTCATGGGA 780

TTCCCGGCAG ATAAGGACTG GGAAGACATT CGGAAGATGC CGGAGTACCC AACACTGCAG 840

AAAGACTTCA GGAGGACAAC GTATGCAACC AGCAGCTTAA TCAAATACAT GGAGAAGCAT 900

AAAGTCAAAC CAGAGAGCAA GGTTTTTCTG CTGCTCCAGA AACTCCTCAC GATGGACCCC 960

ACCAAAAGGA TTACATCAGA GCATTCACTG CAGGACCCGT ACTTCCTGGA GGAGCCATTA 1020

CCAACCACCG ATGTGTTTGC TGGGTGTCAG ATACCGTACC CAAAACGAGA GTTCCTGAAC 1080

GAAGACGAGC CCGAGGAGAA AACAGAAAAG AATCAGACCC AGCCACATCA GCAGACGACG 1140

GGTCAGACTC AGGCCCAGAA CCAGCAGCAG ACAGCCCCCC AGCAGGCTCC CTCCCTGCAG 1200

AACTTGGCCC AAACCAACGG CAATGCAGGA GCAACGGGGG CCGCCACCGG CGGGGGTTTA 1260

CAACACGGCC AGGACCAGGG GCCCCACAAC AAGAAACCTC GGATTGGGCC CTCTGGGGCC 1320

TCCTCAGGCA CTGGGTTGCT ACAGTCGGAG TACCAGCTCT CTGGCTCCCG CCTTGGTTAC 1380

CAAAGCAGCA TCCAAGGTTC CACTCAGCCC CAAGGCACCA TGGGATACTC GTCATCGTCC 1440

CAGCAGAGCT CCCATTACTC CCACCAGACC CACCGTTACT GA 1482

Domain Profile

S: 6     kigeGtygkvykakdke..tgevvAlKkirlekekegvpitalrEisllkelkhknivkL  63

         k+g+Gtyg+vykak+k+  +++ +AlK+i    e +g++++a+rE++ll+elkh+n++ L

Q: 26    KVGRGTYGHVYKAKRKDgkDEKEYALKQI----EGTGISMSACREVALLRELKHPNVIAL  81

         79************986436678******....999************************

S: 64    levva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqlleglay  115

         ++v+  ++++k++L+f+++e+dL++++k ++++       +l++ +vksll+q+l+g++y

Q: 82    QKVFLsHSDRKVWLLFDYAEHDLWHIIKFHRASkgnkkptQLPRGMVKSLLYQILDGIHY  141

         ****94555*********************9999999999********************

S: 116   lHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwYra  168

         lH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wYra

Q: 142   LHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWYRA  201

         *******************9988889*************99999665699**********

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkllgt  219

         PelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++g

Q: 202   PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpfhHDQLDRIFSVMGF  261

         ************************************************************

S: 220   psekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllaldpk  270

         p +k+w++++k+pey    k+f+++++   +l ++++k k    +k + ll+kll++dp+

Q: 262   PADKDWEDIRKMPEYPtlqKDFRRTTYAtsSLIKYMEKHKvkpeSKVFLLLQKLLTMDPT  321

         ***************9654477776665446666664433335456899***********

S: 271   kRisakealqhkyf  284

         kRi++++ lq++yf

Q: 322   KRITSEHSLQDPYF  335

         *************9

Domain Sequence
(FASTA)

KVGRGTYGHV YKAKRKDGKD EKEYALKQIE GTGISMSACR EVALLRELKH PNVIALQKVF 60

LSHSDRKVWL LFDYAEHDLW HIIKFHRASK GNKKPTQLPR GMVKSLLYQI LDGIHYLHAN 120

WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK PLADLDPVVV TFWYRAPELL 180

LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN PFHHDQLDRI FSVMGFPADK 240

DWEDIRKMPE YPTLQKDFRR TTYATSSLIK YMEKHKVKPE SKVFLLLQKL LTMDPTKRIT 300

SEHSLQDPYF 310

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013