EKS-GAA-00342

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00342

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	431.0	2.8E-129	237	526	290

Status

Unreviewed

Ensembl Protein

ENSGACP00000010308

UniProt Accession

G3NY88;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1B (1 of 2)

Gene Synonyms/Alias

BMPR1B (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000007776	ENSGACP00000010308	ENSGACT00000010330

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

537

Protein Sequence
(FASTA)

QSCFRGCFRA LCRFLTFKMY FMMESYIKGN ILDSMLLRAS SKESRESGKE TSGSTAPSLS 60

LQRLLWCHCY HHCPEDSTNN TCRTDGYCFT MVEDEGGVPV LTAGCLGLRG SEFQCRERGN 120

SQRRSLECCT DEDYCNKNLH PILPPLKPPL YVDGNIHNEA MTISVIVCSV ILVFIIVFCY 180

FRYRRQESRG RYSIGLKQDE TYIPPGESLR DLIEQSQSSG SGSGLPLLVQ RTIAKQIYMV 240

KQIGKGRYGE VWMGRWRGEK VAVKVFTTTE EASWFRETEI YQTVLMRHEN ILGFIAADIK 300

GTGSWTQLYL ITDYHENGSL YDYLKSTTLD NRAMLRLAYS SVRGLCHLHN GIIGTQAKPS 360

IAHRDLKSKN ILVKRNGTCC IADLGLSVKF ISDTNEVDIP HNTRVGTKRY MPPEVLEETL 420

DRSKLKSYLM ADMYSFGLIL WEIARRCVSG VKGILEEYQL PYHELVPTDP SYEDMREVVC 480

IKRLRPSFPN RWTSDECLRQ MGKLMTESWA HNPANRLTAL RLKKTLAKMS ESQDIKL 537

Nucleotide Sequence
(FASTA)

CAATCTTGTT TCAGAGGTTG TTTCAGAGCT CTCTGTAGGT TTTTAACTTT TAAAATGTAT 60

TTCATGATGG AATCGTATAT TAAAGGCAAT ATATTGGACA GTATGCTACT AAGAGCATCC 120

AGTAAGGAGT CAAGGGAGAG TGGGAAGGAG ACCAGTGGCA GCACAGCTCC ATCATTGTCC 180

CTCCAACGGC TACTGTGGTG TCACTGTTAT CACCACTGCC CCGAAGATTC AACCAACAAC 240

ACGTGCAGGA CTGATGGCTA TTGTTTCACG ATGGTGGAGG ACGAGGGAGG AGTGCCGGTC 300

CTAACGGCGG GATGCCTCGG CCTCCGGGGA TCAGAATTTC AGTGTAGGGA GAGGGGAAAC 360

TCTCAACGCA GATCACTGGA GTGCTGTACA GACGAGGATT ACTGTAACAA AAACCTGCAT 420

CCCATACTGC CGCCACTCAA ACCACCTCTC TATGTAGATG GAAACATCCA CAACGAAGCC 480

ATGACAATCT CAGTCATTGT GTGCAGCGTT ATCCTGGTTT TCATTATTGT CTTCTGCTAC 540

TTCAGGTATA GACGTCAGGA GTCTCGCGGG CGGTACAGCA TTGGTCTGAA GCAGGATGAG 600

ACCTACATCC CCCCCGGAGA GTCTCTGAGG GACCTGATAG AGCAGTCGCA AAGCTCTGGC 660

TCAGGCTCGG GGCTCCCTCT ATTGGTGCAG CGAACAATAG CCAAGCAGAT CTATATGGTG 720

AAGCAGATCG GCAAGGGGAG GTACGGCGAG GTGTGGATGG GCAGATGGAG GGGAGAAAAG 780

GTGGCGGTCA AAGTCTTCAC CACCACTGAG GAGGCTAGTT GGTTCAGAGA GACTGAGATC 840

TACCAGACAG TCCTAATGAG ACATGAGAAC ATACTGGGTT TTATAGCTGC TGATATTAAA 900

GGAACCGGCT CCTGGACCCA ACTCTACCTA ATCACGGACT ACCATGAAAA CGGCTCCCTG 960

TATGACTACC TGAAGTCGAC TACTCTAGAC AACAGAGCCA TGCTGCGACT GGCCTACTCC 1020

TCCGTCAGAG GCCTCTGTCA CCTCCACAAC GGGATCATAG GCACTCAGGC CAAACCTTCC 1080

ATCGCTCACA GGGACCTGAA GAGTAAGAAC ATACTGGTGA AAAGGAACGG GACCTGCTGT 1140

ATAGCTGACC TGGGGCTGTC GGTCAAGTTT ATCAGTGACA CCAATGAGGT AGACATTCCT 1200

CACAACACCA GAGTGGGTAC AAAGCGCTAC ATGCCTCCAG AGGTTCTGGA AGAGACTTTG 1260

GACCGAAGTA AATTAAAGTC GTACCTAATG GCCGACATGT ACAGCTTTGG GCTCATTCTC 1320

TGGGAGATTG CTCGTCGTTG TGTTTCAGGA GTCAAAGGGA TTCTTGAAGA GTACCAGTTG 1380

CCGTACCACG AGTTAGTTCC TACCGACCCT TCATATGAGG ACATGAGGGA GGTGGTCTGC 1440

ATCAAGAGAC TACGACCCTC CTTTCCAAAT CGATGGACCA GCGATGAGTG TTTGAGACAG 1500

ATGGGGAAGC TGATGACAGA ATCCTGGGCC CACAACCCGG CCAACCGCCT CACAGCCCTT 1560

CGCCTCAAAA AGACACTCGC CAAGATGTCA GAATCGCAAG ACATTAAGCT GTGA 1614

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         + ++++igkGrygeVw++++rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 237   IYMVKQIGKGRYGEVWMGRWRGEKVAVKVFTTTEEASWFRETEIYQTVLMRHENILGFIA  296

         56899*******************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+dyLk++tld + +lrla+s ++Gl+hLH+ i gt+

Q: 297   ADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDNRAMLRLAYSSVRGLCHLHNGIIGTQ  356

         ***********************************************************8

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

            Kp+iaHRDlkskNilvk+++tcciaDlGL++k+ ++++e+d+ +n++vGtkRYm PE

Q: 357   A--KPSIAHRDLKSKNILVKRNGTCCIADLGLSVKFISDTNEVDIPHNTRVGTKRYMPPE  414

         7..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRcee.vdeeveeyklpfeevvgsdPslee  239

         vlee+l+ ++++++ +aD+Ys+gL+lWE+a+Rc + v+++ eey+lp++e v++dPs+e+

Q: 415   VLEETLDRSKLKSYLMADMYSFGLILWEIARRCVSgVKGILEEYQLPYHELVPTDPSYED  474

         ***********************************9************************

S: 240   mkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         m+evv+ k+lrP++p++w+++e+l+++ kl++e+W+++p+ Rltalr+kk+l

Q: 475   MREVVCIKRLRPSFPNRWTSDECLRQMGKLMTESWAHNPANRLTALRLKKTL  526

         **************************************************97

Domain Sequence
(FASTA)

IYMVKQIGKG RYGEVWMGRW RGEKVAVKVF TTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDNRAMLR LAYSSVRGLC HLHNGIIGTQ 120

AKPSIAHRDL KSKNILVKRN GTCCIADLGL SVKFISDTNE VDIPHNTRVG TKRYMPPEVL 180

EETLDRSKLK SYLMADMYSF GLILWEIARR CVSGVKGILE EYQLPYHELV PTDPSYEDMR 240

EVVCIKRLRP SFPNRWTSDE CLRQMGKLMT ESWAHNPANR LTALRLKKTL 290

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013