EKS-GAA-00291

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00291

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	397.1	6.0E-119	92	352	261

Status

Unreviewed

Ensembl Protein

ENSGACP00000011821

UniProt Accession

G3P2J8;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000008933	ENSGACP00000011821	ENSGACT00000011845
ENSGACG00000008933	ENSGACP00000011824	ENSGACT00000011848

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

565

Protein Sequence
(FASTA)

MARAKSQLYD VVPIQPSVVI CSCSHPSMVR NHADSCSPLA IPGASSSHCP GIQGSPSEPR 60

AVGASASSQG SDIRTQPAMQ TPQPRKKKPE DFRFGRILGE GSFSTVVLAR EQGTGKEYAI 120

KILEKRHIVK ANKAQYVKRE RDLMSNLEHP FFVKLYFTFQ DDEKLYFGLS YAKNGELLKY 180

IRKIGSFDET CTRFYSAEIV CALEYLHNKG IIHRDLKPEN ILLSEDMHIQ ITDFGTAKQL 240

SSDSKQARAN SFVGTAQYVS PELLTEKSAC KSSDLWALGC ITYQLVAGLP PFRAGNEYLI 300

FQKIIKLEYE FPEKFFPKAK DLVKQLLSLD PSKRIGCEEM GGYDPLRQHP FFDTISWSDL 360

HLQTPPKLTP YLPAMSEDDE DCYGNYDDLL SQFSNMQVAQ SSSTHSLSPH ESTPPQRSSS 420

NIEQYIHDLD NNSFELDLQF TVEEKQLLLD KQTTGNPWHQ FVENNLILKM GPVDKRKGLF 480

ARRRQLLLTE GPHLYYVDPV NKVLKGEIPW SLELRPEAKN FKTFFVHTPN RTYYLMDPSG 540

NADRWCKKIQ EVWRKIYQRP QNPGL 565

Nucleotide Sequence
(FASTA)

ATGGCAAGGG CCAAAAGTCA GCTGTATGAT GTTGTGCCCA TTCAGCCCAG CGTTGTCATC 60

TGTTCCTGCT CGCATCCATC AATGGTAAGA AACCACGCTG ACTCCTGCTC GCCACTTGCT 120

ATCCCAGGCG CAAGCAGTAG CCACTGTCCC GGCATACAGG GCTCACCCTC AGAGCCCCGT 180

GCTGTTGGAG CGTCTGCAAG CAGCCAGGGC TCAGACATCA GGACGCAGCC GGCCATGCAG 240

ACCCCTCAGC CACGCAAGAA GAAGCCAGAG GACTTCAGAT TTGGCAGGAT ACTGGGAGAG 300

GGCTCCTTCT CGACGGTTGT TTTGGCGAGA GAGCAGGGAA CGGGAAAAGA ATATGCAATT 360

AAGATTTTAG AGAAGCGCCA TATTGTGAAG GCGAACAAAG CCCAGTACGT GAAAAGAGAA 420

AGGGATTTGA TGTCAAATCT AGAACACCCA TTCTTCGTCA AGCTCTACTT CACATTTCAA 480

GATGATGAGA AGTTGTATTT TGGCCTCAGC TACGCTAAGA ATGGCGAGCT GCTGAAATAC 540

ATTCGCAAAA TCGGTTCTTT TGATGAGACC TGTACTAGAT TCTATTCAGC TGAAATAGTT 600

TGTGCTCTGG AATACTTACA CAATAAGGGG ATAATACACA GAGATCTGAA ACCAGAGAAT 660

ATTCTCCTGA GTGAAGACAT GCACATTCAG ATAACAGATT TTGGGACAGC AAAACAGTTA 720

TCATCAGACA GTAAACAAGC GAGAGCAAAC TCCTTTGTCG GAACAGCACA GTACGTGTCT 780

CCAGAGCTAC TAACAGAGAA ATCTGCTTGC AAGAGCTCTG ACCTCTGGGC CTTGGGATGT 840

ATTACCTATC AGCTGGTGGC TGGTTTACCA CCTTTCAGAG CTGGAAATGA GTACCTAATA 900

TTCCAGAAGA TAATAAAGCT GGAGTATGAA TTCCCAGAGA AATTCTTCCC CAAAGCCAAG 960

GATCTTGTCA AACAGCTTTT GTCTCTGGAC CCTTCCAAGC GGATTGGGTG TGAAGAGATG 1020

GGAGGCTACG ACCCTTTGAG GCAGCACCCC TTCTTTGACA CTATCTCCTG GAGTGACCTA 1080

CACCTACAGA CACCCCCCAA GCTCACCCCC TACCTGCCAG CCATGTCTGA GGATGATGAG 1140

GACTGCTATG GAAACTATGA TGACCTCCTG AGCCAGTTCA GCAACATGCA GGTGGCCCAG 1200

TCCAGCTCCA CACACTCCCT GTCGCCACAC GAGTCCACAC CCCCGCAGAG GTCCAGCAGC 1260

AACATTGAGC AGTACATTCA TGACCTGGAC AATAACTCTT TTGAGTTGGA CCTGCAGTTC 1320

ACTGTAGAAG AGAAGCAGCT GTTGCTGGAC AAACAGACCA CTGGAAACCC CTGGCACCAG 1380

TTTGTGGAGA ATAACCTGAT CCTGAAGATG GGCCCAGTGG ATAAAAGGAA GGGTCTGTTT 1440

GCCAGACGGA GACAGCTGCT TCTCACTGAA GGACCACACC TGTATTACGT GGATCCTGTA 1500

AACAAGGTCC TGAAAGGGGA GATTCCTTGG TCCCTAGAGC TACGCCCTGA GGCCAAGAAC 1560

TTCAAAACCT TCTTTGTTCA CACGCCTAAC CGAACATACT ATTTGATGGA CCCAAGCGGA 1620

AATGCAGACA GATGGTGCAA GAAGATCCAG GAAGTGTGGA GAAAGATCTA TCAGAGGCCC 1680

CAAAATCCAG GCCTATAG 1698

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         f f+++lgeGs+stvvlare+ + keyaik+lekr+i+k +k +yv+re++ +++l ehp

Q: 92    FRFGRILGEGSFSTVVLAREQGTGKEYAIKILEKRHIVKANKAQYVKRERDLMSNL-EHP  150

         789*****************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++ ale+lh+kg

Q: 151   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYSAEIVCALEYLHNKG  210

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl +d++i+itDfG+ak l++++k+         ar++sfvGta+yvsP

Q: 211   IIHRDLKPENILLSEDMHIQITDFGTAKQLSSDSKQ---------ARANSFVGTAQYVSP  261

         ******************************777766.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci yql+aG+pPfra neylif+ki+kley+fpe+f++kakd

Q: 262   ELLTEKSACKSSDLWALGCITYQLVAGLPPFRAGNEYLIFQKIIKLEYEFPEKFFPKAKD  321

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lv++lL  d+++r+++ee      +++h+ff

Q: 322   LVKQLLSLDPSKRIGCEEmggydpLRQHPFF  352

         ******************************9

Domain Sequence
(FASTA)

FRFGRILGEG SFSTVVLARE QGTGKEYAIK ILEKRHIVKA NKAQYVKRER DLMSNLEHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYSAEIVC ALEYLHNKGI 120

IHRDLKPENI LLSEDMHIQI TDFGTAKQLS SDSKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI TYQLVAGLPP FRAGNEYLIF QKIIKLEYEF PEKFFPKAKD LVKQLLSLDP 240

SKRIGCEEMG GYDPLRQHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013