EKS-GAA-00185

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00185

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	614.2	3.7E-185	470	749	280

Status

Unreviewed

Ensembl Protein

ENSGACP00000011946

UniProt Accession

G3P2X3;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK2 (1 of 2)

Gene Synonyms/Alias

TLK2 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000009044	ENSGACP00000011946	ENSGACT00000011970

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

780

Protein Sequence
(FASTA)

MMEELHSLDP RRQELLEARF TGVGVAKGSG QNQNESSNQS LCSVGSLSDK ELETPEKKAN 60

DQRVRKRKAD HFDSQGKAGA RGHKISDYFE FAGGSGPGTS PARGIPPVVR SSPQHSLSNP 120

PVTVRPFALS SVSCFFSSSV VLSSTLGLTS LAFMNSLTSL NPVFKTLSIC VSVFYFAFMN 180

VFASKVQQGS PSSVNSANTE QSTCSLKPAS LHMLHKATQS DLTIEKLTAM EINKNSDLEK 240

KEGRIDDLLR ANCDLRRQID EQQRMLERYK ERLNKCVTMS KKLLIEKSKQ EKMACRDKSM 300

QDRLRLGHFT TVRHGASFSE QWTDGYAFQN LIKQQERINS QREDIERQRK LLAKRKPPSM 360

AQTPPPSLEQ NKRKSKTNGT ESEAHFPAAC VFKVEARFVL GPCRLSQAEY HEQEEIFKLR 420

LGHLKKEEAE IQAELERLER VRNLHIRELK RIHNEDNSQF KDHPTLNDRY LLLHLLGRGG 480

FSEVYKAFDL TEQRYVAVKI HQLNKNWRDE KKENYHKHAC REYRIHKELD HPRIVKLYDY 540

FSLDTDSFCT VLEYCEGNDL DFYLKQHKLM SEKEGRSIIM QIVNALKYLN EIRPPIIHYD 600

LKPGNILLVN GTACGEIKIT DFGLSKIMDD DSYNSVDGME LTSQGAGTYW YLPPECFVVG 660

KEPPKISNKV DVWSVGVIFY QCLYGRKPFG HNQSQQDILQ ENTILKATDV QFPPKPVVTP 720

EAKAFIRRCL VYRKEDRIDV HQLASDPFLM PHIRKSVASS GTSGTAVAST SSSSNSSASN 780

Nucleotide Sequence
(FASTA)

ATGATGGAAG AACTGCATAG CCTGGACCCC CGACGGCAGG AGCTATTGGA AGCTCGCTTC 60

ACTGGGGTCG GGGTGGCTAA GGGCTCGGGT CAGAACCAAA ATGAGTCGTC CAACCAGAGT 120

CTTTGCAGCG TAGGCTCGCT CAGTGACAAA GAACTGGAGA CTCCCGAGAA AAAGGCAAAC 180

GACCAGAGAG TAAGGAAACG GAAAGCAGAC CATTTTGACA GCCAAGGCAA AGCAGGTGCC 240

AGGGGACATA AAATTAGTGA TTATTTTGAG TTTGCGGGAG GCAGCGGTCC TGGTACCAGC 300

CCTGCTAGGG GAATTCCACC AGTGGTCCGT TCTTCCCCAC AACACTCACT TTCCAACCCC 360

CCTGTCACGG TGAGGCCGTT TGCTCTATCA TCTGTCTCTT GCTTTTTCTC TTCATCTGTC 420

GTTCTGTCTT CCACGCTTGG TTTAACATCC CTGGCTTTCA TGAATTCTTT AACGTCATTA 480

AATCCAGTTT TTAAGACCCT CTCTATCTGT GTAAGTGTTT TTTATTTTGC ATTCATGAAT 540

GTTTTTGCCT CTAAGGTGCA GCAGGGAAGC CCCTCCTCCG TGAACTCGGC CAACACAGAG 600

CAATCAACGT GTTCGTTGAA GCCAGCGTCT CTTCACATGC TCCACAAAGC CACACAGTCT 660

GACCTTACTA TAGAGAAACT AACAGCAATG GAGATCAACA AGAACTCTGA CCTGGAGAAG 720

AAGGAGGGCC GAATAGACGA TTTGCTGCGG GCAAACTGTG ATCTCAGGAG ACAAATTGAT 780

GAACAGCAGA GGATGTTGGA ACGATACAAG GAACGCTTAA ATAAGTGTGT GACCATGTCC 840

AAGAAGCTGC TGATTGAAAA ATCCAAACAG GAGAAGATGG CGTGCAGGGA CAAAAGCATG 900

CAGGACAGGC TAAGACTCGG TCACTTCACC ACAGTGAGAC ATGGCGCGTC TTTTTCTGAG 960

CAGTGGACGG ATGGATATGC CTTCCAAAAC CTCATCAAAC AACAAGAACG GATCAATTCC 1020

CAGAGAGAGG ACATTGAAAG ACAGAGGAAG CTGCTGGCCA AACGCAAGCC GCCCTCCATG 1080

GCCCAGACGC CACCTCCCAG CCTGGAGCAA AACAAGCGCA AAAGCAAAAC CAATGGAACA 1140

GAAAGTGAAG CCCATTTTCC TGCTGCGTGC GTATTCAAAG TTGAAGCAAG GTTTGTTCTG 1200

GGTCCCTGCA GGTTATCGCA GGCAGAGTAC CATGAACAAG AGGAAATCTT TAAGCTACGA 1260

CTAGGCCATC TAAAAAAGGA GGAAGCAGAG ATCCAGGCAG AGCTGGAGAG GTTGGAGCGA 1320

GTACGAAACC TCCACATTCG AGAGCTGAAA AGGATTCACA ACGAGGATAA TTCTCAATTC 1380

AAAGATCACC CTACGCTAAA TGACCGGTAT CTGCTACTCC ATTTACTTGG ACGGGGAGGT 1440

TTCAGTGAAG TTTACAAGGC CTTTGACTTG ACAGAACAAA GGTATGTTGC TGTCAAAATC 1500

CACCAGTTAA ACAAGAACTG GAGGGATGAG AAGAAAGAAA ACTATCACAA ACACGCATGC 1560

AGAGAATATA GAATCCACAA AGAACTGGAC CACCCACGAA TAGTTAAACT CTACGATTAC 1620

TTTTCGCTTG ACACTGACTC GTTCTGCACG GTCCTGGAGT ACTGCGAAGG CAATGACTTG 1680

GACTTCTACC TGAAGCAGCA CAAGCTTATG TCAGAGAAGG AGGGCCGCTC CATCATCATG 1740

CAGATAGTCA ACGCCCTGAA GTACCTCAAT GAGATCAGAC CGCCCATTAT CCACTACGAC 1800

CTTAAACCCG GTAACATCCT CCTGGTGAAC GGCACCGCCT GTGGGGAGAT CAAGATTACA 1860

GACTTTGGCC TGTCGAAGAT CATGGATGAT GACAGCTACA ACTCAGTGGA CGGGATGGAG 1920

CTGACGTCAC AGGGAGCAGG CACATACTGG TATCTGCCCC CAGAGTGCTT TGTGGTTGGA 1980

AAAGAACCAC CTAAAATCTC CAACAAGGTG GATGTGTGGT CTGTGGGAGT CATTTTCTAC 2040

CAGTGTTTGT ACGGCCGCAA GCCCTTTGGC CACAACCAGT CGCAGCAGGA CATCCTGCAG 2100

GAGAACACCA TACTAAAGGC AACAGATGTG CAGTTTCCCC CAAAACCAGT TGTCACACCT 2160

GAAGCTAAGG CCTTTATAAG GCGCTGTCTA GTCTACCGTA AGGAGGACCG CATCGATGTG 2220

CACCAGCTGG CCAGTGACCC CTTCCTCATG CCCCACATCC GCAAGTCGGT GGCCTCCTCG 2280

GGCACCTCGG GCACGGCCGT GGCCTCCACA TCCAGCTCCT CCAACAGCAG CGCCTCAAAC 2340

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqryvavkihqlnk+w+dekkeny+kha+reyrihkel

Q: 470   YLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKEL  529

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtdsfctvley+egndldfylkqhkl+seke rsiimqiv+alkyl

Q: 530   DHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEGRSIIMQIVNALKYL  589

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         nei+ppiihydlkpgnillv+gtacgeikitdfglskimdddsy+s+dg+eltsqgagty

Q: 590   NEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTY  649

         ************************************************************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvifyqclyg+kpfghnqsqqdil+entilkat+

Q: 650   WYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATD  709

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvv++eakafirrcl yrkedridv+qla+d++l

Q: 710   VQFPPKPVVTPEAKAFIRRCLVYRKEDRIDVHQLASDPFL  749

         *************************************986

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LTEQRYVAVK IHQLNKNWRD EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDSFC TVLEYCEGND LDFYLKQHKL MSEKEGRSII MQIVNALKYL 120

NEIRPPIIHY DLKPGNILLV NGTACGEIKI TDFGLSKIMD DDSYNSVDGM ELTSQGAGTY 180

WYLPPECFVV GKEPPKISNK VDVWSVGVIF YQCLYGRKPF GHNQSQQDIL QENTILKATD 240

VQFPPKPVVT PEAKAFIRRC LVYRKEDRID VHQLASDPFL 280

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013