EKS-GAA-00285

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00285

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	422.1	1.1E-126	70	331	262

Status

Unreviewed

Ensembl Protein

ENSGACP00000012959

UniProt Accession

G3P5T6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3 (1 of 2)

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000009789	ENSGACP00000012959	ENSGACT00000012983

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

410

Protein Sequence
(FASTA)

MLQNGNGNEK PLRAPKAEAE PDSPADEAKL RQHTPPETGA QDPGGEFTHF PLPAYPKLEI 60

KRYAVTDDYK ISTQVLGLGI SGKVLQCFNK KTGEKCALKI LYDSPKARRE VELHWRVSGG 120

PYIVRIISLY ENMHHGKKCL LIIMECMEGG ELFNRIQARG DQAFTEKEAS EIMKDIGTAI 180

EYLHHINIAH RDIKPENLLY TIKERNGVLK LTDFGFAKET TLDNSLQTPC YTPYYVAPEV 240

LGPEKYDKSC DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKRRIRMGQY EFPNPEWAEV 300

SQEAKDLINE LLKTDPNERM TIIQFMNHPW INKSMVVPST PLHTTRVLTE DREMWDDVKE 360

EMTSALATMR VDYDQVKIKD LDTSSNPLLN KRRKKAAAGA KGGSTVCQSQ 410

Nucleotide Sequence
(FASTA)

ATGCTGCAAA ATGGAAACGG AAACGAGAAG CCGCTGCGAG CGCCAAAAGC CGAGGCAGAG 60

CCGGACTCCC CGGCTGACGA GGCGAAACTG CGGCAGCACA CTCCCCCCGA AACCGGCGCA 120

CAGGACCCGG GCGGCGAGTT CACGCACTTC CCCTTGCCCG CTTACCCCAA ATTGGAGATA 180

AAGCGCTACG CGGTGACGGA CGATTACAAG ATCTCCACTC AGGTTCTGGG CTTAGGGATC 240

AGTGGCAAAG TGCTTCAGTG CTTCAACAAG AAGACTGGAG AGAAGTGTGC ACTGAAGATT 300

CTCTACGACA GCCCCAAAGC CAGGCGAGAG GTGGAGCTGC ACTGGCGGGT ATCCGGAGGG 360

CCGTACATTG TTCGCATCAT CAGCCTGTAT GAAAACATGC ATCACGGGAA GAAGTGCCTG 420

CTCATCATCA TGGAGTGTAT GGAGGGAGGA GAGCTGTTCA ACCGAATCCA GGCCAGAGGA 480

GACCAGGCTT TCACTGAGAA AGAGGCTTCT GAGATCATGA AGGACATCGG CACGGCCATT 540

GAGTATCTCC ACCACATCAA CATCGCTCAC AGAGACATCA AGCCAGAGAA CTTGCTGTAC 600

ACCATCAAAG AAAGAAACGG GGTCCTGAAA CTGACCGACT TTGGCTTTGC TAAGGAGACG 660

ACGCTAGACA ACTCTCTACA GACCCCCTGT TACACGCCGT ACTACGTGGC CCCTGAAGTT 720

TTGGGCCCAG AGAAATACGA CAAGTCATGT GACATGTGGT CGCTGGGCGT CATCATGTAC 780

ATCCTGCTGT GTGGTTTCCC CCCGTTTTAC TCCAACACGG GCCAGGCCAT TTCCCCGGGG 840

ATGAAGAGAA GGATCAGGAT GGGCCAGTAC GAGTTCCCCA ACCCAGAGTG GGCTGAGGTG 900

TCCCAGGAAG CCAAAGATTT GATCAATGAG CTGCTGAAGA CAGACCCTAA CGAGAGGATG 960

ACCATCATTC AGTTCATGAA CCACCCCTGG ATTAATAAGT CCATGGTGGT TCCCTCCACT 1020

CCGCTCCACA CCACCCGGGT GCTGACTGAA GACAGAGAGA TGTGGGACGA TGTGAAGGAG 1080

GAGATGACCA GCGCTCTAGC GACCATGCGT GTGGACTACG ACCAGGTGAA GATCAAAGAC 1140

CTCGACACCT CCAGCAACCC GCTGCTCAAC AAGAGACGCA AGAAGGCCGC CGCGGGGGCC 1200

AAGGGGGGCT CCACGGTCTG CCAAAGTCAG TGA 1233

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         k++++vlG Gisgkvl+c++kktgek+alkil+d++k+rrevelh+++sg ++iv++i +

Q: 70    KISTQVLGLGISGKVLQCFNKKTGEKCALKILYDSPKARREVELHWRVSGGPYIVRIISL  129

         5789********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en+++++k+ll+++e++eGGel++riq r  +aftekease++kdi++a+++lh+ nia

Q: 130   YENMHHGKKCLLIIMECMEGGELFNRIQARgdQAFTEKEASEIMKDIGTAIEYLHHINIA  189

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+ ke+n ++kl+Dfg+aket+ +++l+tpc+t++yvaPevl++ek

Q: 190   HRDIKPENLLYTIKERNGVLKLTDFGFAKETTLDNSLQTPCYTPYYVAPEVLGPEK----  245

         ********************************************************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri++g+yefP++eW+evs+ea

Q: 246   -YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRMGQYEFPNPEWAEVSQEA  304

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         kdli++lLk+dp+er+ti +++nhpw+

Q: 305   KDLINELLKTDPNERMTIIQFMNHPWI  331

         **************************8

Domain Sequence
(FASTA)

KISTQVLGLG ISGKVLQCFN KKTGEKCALK ILYDSPKARR EVELHWRVSG GPYIVRIISL 60

YENMHHGKKC LLIIMECMEG GELFNRIQAR GDQAFTEKEA SEIMKDIGTA IEYLHHINIA 120

HRDIKPENLL YTIKERNGVL KLTDFGFAKE TTLDNSLQTP CYTPYYVAPE VLGPEKYDKS 180

CDMWSLGVIM YILLCGFPPF YSNTGQAISP GMKRRIRMGQ YEFPNPEWAE VSQEAKDLIN 240

ELLKTDPNER MTIIQFMNHP WI 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013