EKS-GAA-00458

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00458

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Src	337.3	7.2E-101	248	494	247

Status

Unreviewed

Ensembl Protein

ENSGACP00000013609

UniProt Accession

G3P7N7;

Protein Name

Protein Synonyms/Alias

Gene Name

PTK6

Gene Synonyms/Alias

PTK6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000010303	ENSGACP00000013611	ENSGACT00000013636
ENSGACG00000010303	ENSGACP00000013609	ENSGACT00000013634

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

503

Protein Sequence
(FASTA)

MAECVRKACP CLGALWQRIF SDKKPPPAAE GDAGGDGEVE VSSADDEPRT PITASDAVPE 60

GGSMFRALWA FESRHQDELS FQEGDLFTVV NRSGDWWSAR KIEKNGRVLE TGIVPKNYLE 120

RAESLQMQQW YFGQMNRFES QGHLLGSEND DGAFLIRRSE KENIGYVLSV RSGSRVKHFK 180

VLRAEGSLFF VEYNKKFSSL IDLVEHYCGN NMLNIGTLGK PCKRKKPTTT DLNHFTVDEW 240

ELPKEEFTLE EQLGTGYFAE VYRGRWKNHI NVAIKIIKKS ELNHLEFQRE VQMLKSLRHP 300

HLISLFATCT VSAANYKTEL MEKGSLLTFL RGSEGRSQDI GSLIDMGAQV ADGMSYLEEK 360

NSIHRDLAAR NVLVGEDYMC KVADFGLARV IKEPFYITED KKIPYKWSAP EAISHGKFSN 420

KSDVWSFGVL LYEILTYGGV PYPAFTNQET YQQVTDGFRM PAPNNCSESL YKVMLSCWSA 480

DPSDRPSFHD LKVKLDSSSY EME 503

Nucleotide Sequence
(FASTA)

ATGGCCGAGT GTGTGCGTAA AGCGTGCCCG TGCCTGGGCG CGCTGTGGCA GAGGATCTTC 60

AGCGACAAAA AGCCTCCTCC CGCAGCGGAA GGTGATGCAG GAGGAGACGG CGAGGTGGAG 120

GTCTCCTCCG CTGATGACGA ACCCCGGACT CCGATCACCG CGTCGGACGC GGTGCCCGAG 180

GGAGGCTCCA TGTTCAGAGC GCTCTGGGCG TTTGAGTCCC GGCACCAGGA CGAGCTGTCG 240

TTCCAGGAGG GAGATCTGTT CACCGTGGTC AACCGCAGCG GAGACTGGTG GTCCGCGCGG 300

AAGATCGAAA AGAACGGACG CGTCCTGGAG ACCGGGATCG TGCCCAAAAA CTACCTGGAA 360

CGGGCCGAGT CCCTACAGAT GCAACAGTGG TATTTTGGTC AAATGAACCG CTTTGAGTCC 420

CAAGGCCACC TGCTGGGCTC AGAAAACGAC GACGGAGCTT TCCTCATCAG ACGAAGTGAG 480

AAAGAAAACA TTGGATACGT TCTTTCAGTG AGATCAGGCA GTCGGGTGAA GCATTTTAAG 540

GTCCTCAGAG CAGAGGGAAG TTTGTTTTTC GTGGAGTACA ACAAGAAATT CAGTTCTCTA 600

ATCGACTTGG TGGAGCACTA CTGCGGCAAC AACATGCTCA ACATCGGCAC GCTGGGAAAA 660

CCATGCAAGA GGAAAAAGCC CACCACCACA GATTTGAATC ATTTCACTGT GGATGAGTGG 720

GAGCTCCCGA AAGAAGAGTT CACCCTGGAG GAGCAGCTGG GCACTGGGTA CTTCGCTGAA 780

GTCTACCGGG GACGCTGGAA AAATCACATT AACGTCGCCA TCAAGATCAT CAAAAAATCG 840

GAGTTGAACC ACCTGGAATT TCAGAGGGAA GTTCAGATGC TGAAGAGTCT GCGCCATCCT 900

CACCTCATCT CTCTGTTTGC TACATGTACA GTCTCAGCAG CCAACTACAA AACCGAACTG 960

ATGGAGAAAG GCAGCCTGCT TACTTTCCTC AGAGGTTCAG AGGGTCGGAG TCAAGACATT 1020

GGATCCCTCA TTGACATGGG GGCCCAGGTG GCTGATGGGA TGTCATACCT GGAGGAGAAG 1080

AACAGCATCC ACAGAGATTT GGCAGCTCGA AATGTCCTGG TGGGGGAGGA CTACATGTGT 1140

AAGGTGGCGG ACTTTGGATT GGCCAGAGTG ATCAAGGAGC CGTTCTACAT CACAGAAGAT 1200

AAAAAGATCC CCTACAAGTG GAGCGCTCCT GAGGCCATCA GCCACGGGAA GTTCTCCAAC 1260

AAGTCAGACG TCTGGTCTTT TGGTGTCTTG CTTTATGAGA TTTTGACCTA TGGAGGCGTT 1320

CCTTACCCAG CCTTCACCAA CCAGGAAACC TACCAGCAGG TCACCGACGG TTTCAGGATG 1380

CCAGCTCCGA ACAATTGTTC TGAATCTCTC TACAAAGTTA TGCTCAGCTG TTGGAGCGCC 1440

GACCCCTCCG ACAGGCCCAG CTTTCACGAC CTCAAAGTCA AACTGGACAG CAGCTCCTAC 1500

GAGATGGAGT GA 1512

Domain Profile

S: 2     klvkklGeGqfGevwlgkwkgsvkvavktlkegtlspeafleeaqilkklrheklvklya  61

         +l+++lG+G+f ev+ g+wk++++va+k +k+++l++ +f++e+q+lk+lrh++l++l+a

Q: 248   TLEEQLGTGYFAEVYRGRWKNHINVAIKIIKKSELNHLEFQREVQMLKSLRHPHLISLFA  307

         6899********************************************************

S: 62    vvseeePiyivtelmakGslldflkeeegkklklpklvdlaaqvaeGmayleeknlihrd  121

          ++     y  telm+kGsll+fl+ +eg+++ + +l+d+ aqva+Gm+yleekn ihrd

Q: 308   TCTVSAANY-KTELMEKGSLLTFLRGSEGRSQDIGSLIDMGAQVADGMSYLEEKNSIHRD  366

         ****66666.6*************************************************

S: 122   laarnvlvgeslvvkvadfGlarlieddeytakegaklPikWtaPeaiklgkftiksdvW  181

         laarnvlvge+ ++kvadfGlar+i++  y + e++k+P+kW aPeai+ gkf+ ksdvW

Q: 367   LAARNVLVGEDYMCKVADFGLARVIKEPFYIT-EDKKIPYKWSAPEAISHGKFSNKSDVW  425

         **************************999986.569************************

S: 182   sfGillteivtkGkvPypGmtneevleqvergyrlprpeecpeelyelllecwkkdpeer  241

         sfG+ll+ei+t+G vPyp +tn+e+ +qv+ g+r+p p++c e+ly+++l+cw++dp++r

Q: 426   SFGVLLYEILTYGGVPYPAFTNQETYQQVTDGFRMPAPNNCSESLYKVMLSCWSADPSDR  485

         ************************************************************

S: 242   Ptfetlqev  250

         P+f+ l+ +

Q: 486   PSFHDLKVK  494

         ****99876

Domain Sequence
(FASTA)

TLEEQLGTGY FAEVYRGRWK NHINVAIKII KKSELNHLEF QREVQMLKSL RHPHLISLFA 60

TCTVSAANYK TELMEKGSLL TFLRGSEGRS QDIGSLIDMG AQVADGMSYL EEKNSIHRDL 120

AARNVLVGED YMCKVADFGL ARVIKEPFYI TEDKKIPYKW SAPEAISHGK FSNKSDVWSF 180

GVLLYEILTY GGVPYPAFTN QETYQQVTDG FRMPAPNNCS ESLYKVMLSC WSADPSDRPS 240

FHDLKVK 247

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR000980	; SH2.
IPR001452	; SH3_domain.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF00017	; SH2; 1.
PF00018	; SH3_1; 1.

SMARTs

SM00252	; SH2; 1.
SM00326	; SH3; 1.
SM00219	; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS50001	; SH2; 1.
PS50002	; SH3; 1.

Prints

PR00401	; SH2DOMAIN.
PR00452	; SH3DOMAIN.
PR00109	; TYRKINASE.

Created Date

20-Feb-2013