EKS-GAA-00253

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00253

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	390.1	7.9E-117	4	285	282

Status

Unreviewed

Ensembl Protein

ENSGACP00000014042

UniProt Accession

G3P8W8;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000010619	ENSGACP00000014042	ENSGACT00000014067

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

378

Protein Sequence
(FASTA)

MNCYKTIKKI GEGTFSEVLK TQSLKDGKFY ACKTMKQRIN SLEHANNLRE VQAMKRLSPH 60

ANIIQLHELI FDKETGTVSL ICELMEMNIY EFIQGRQTPL SDNTVKNYMY QLCRSLEHMH 120

SCGIFHRDVK PENILIKQNG LKLGDFGSCR SVHSKPPHTE YISTRWYRAP ECLLTDGYYG 180

LKMDMWSAGC VFFEIMSLSP LFPGTNELDQ VAKIHDVLGT PDLTILQKLK HSRAMLYNFP 240

PKKGSGISRL VPHCPGPALS LLYQMLAYDP DERITAETAM RHTYFREIRQ TEKKAETFHR 300

ASGTMNDWRA LRRTTPGKQH NMKHVAEPAT RRNVPPRPTE LPKLNLLLPG PQMSFPVSAT 360

PSFTATHRGT LPAITSKK 378

Nucleotide Sequence
(FASTA)

ATGAACTGCT ACAAAACAAT CAAGAAAATT GGGGAAGGCA CATTTTCAGA GGTGTTGAAA 60

ACTCAGAGCC TGAAAGATGG GAAGTTTTAC GCATGTAAAA CCATGAAGCA GAGAATTAAC 120

AGTCTGGAGC ACGCCAACAA TCTGCGGGAA GTCCAGGCAA TGAAGAGACT GAGCCCACAT 180

GCAAATATCA TCCAGCTACA TGAACTGATT TTTGACAAAG AAACTGGAAC TGTGTCTCTG 240

ATTTGTGAGC TGATGGAGAT GAACATCTAT GAGTTCATAC AAGGAAGACA AACGCCGCTG 300

TCTGATAATA CAGTAAAGAA CTACATGTAC CAGCTTTGCA GGTCGCTTGA ACACATGCAC 360

AGCTGTGGGA TCTTTCACAG GGATGTGAAG CCAGAAAACA TTCTCATCAA ACAAAACGGT 420

CTGAAGCTTG GCGACTTCGG CTCATGTCGC AGCGTGCACT CCAAGCCGCC GCATACCGAG 480

TACATCTCCA CGCGCTGGTA CAGAGCGCCA GAGTGCCTCC TCACCGATGG CTACTACGGC 540

TTAAAGATGG ACATGTGGAG TGCTGGCTGT GTCTTCTTTG AGATCATGAG TTTGAGTCCT 600

CTCTTCCCGG GAACCAATGA GTTGGACCAG GTCGCTAAGA TCCACGACGT GTTGGGGACG 660

CCAGATCTAA CGATCCTCCA AAAGTTAAAG CATTCCAGAG CGATGCTTTA CAACTTCCCC 720

CCTAAAAAAG GCAGCGGTAT CTCCCGATTA GTCCCCCACT GCCCGGGTCC AGCTCTGTCC 780

CTGCTCTACC AGATGCTCGC CTACGACCCC GATGAACGCA TTACTGCGGA AACAGCAATG 840

CGGCACACAT ACTTCAGGGA AATCAGGCAA ACAGAGAAGA AAGCCGAGAC TTTTCACAGG 900

GCATCTGGGA CTATGAATGA CTGGAGAGCG TTGAGACGCA CAACACCCGG CAAACAGCAC 960

AACATGAAAC ATGTGGCGGA GCCCGCGACC CGACGCAACG TCCCCCCTCG TCCAACCGAG 1020

CTACCCAAAC TCAACCTGCT TTTGCCGGGA CCACAGATGT CCTTCCCTGT CTCCGCCACG 1080

CCTTCCTTTA CCGCCACCCA CCGAGGCACT CTGCCAGCCA TCACGTCGAA AAAG 1134

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+ikk+G+Gtf+evl+++slk+g+ +a+k+mk++++sle+++nlrev+++k+l++h+ni

Q: 4     YKTIKKIGEGTFSEVLKTQSLKDGKFYACKTMKQRINSLEHANNLREVQAMKRLSPHANI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         i+l+e+i+d+e +++ l++elme+n+y++i++r++ ls +++k+++yq++++l+++h  g

Q: 64    IQLHELIFDKETGTVSLICELMEMNIYEFIQGRQTPLSDNTVKNYMYQLCRSLEHMHSCG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++ +kl+dfG++r+v+sk+P+t+y+strwyraPe+ll++g+y  +

Q: 124   IFHRDVKPENILIK-QNGLKLGDFGSCRSVHSKPPHTEYISTRWYRAPECLLTDGYYGLK  182

         **************.8899*****************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+w++Gcv+ e+++l plfPG++e+dq+ ki++vlGtP+ + +++  k ++a+ ++fp

Q: 183   MDMWSAGCVFFEIMSLSPLFPGTNELDQVAKIHDVLGTPDLTILQK-LKHSRAMLYNFPP  241

         ********************************************99.9************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs++++lv+++   al+ll ++laydPder+ta+ a+++ yf

Q: 242   KKGSGISRLVPHCPGPALSLLYQMLAYDPDERITAETAMRHTYF  285

         *******************************************9

Domain Sequence
(FASTA)

YKTIKKIGEG TFSEVLKTQS LKDGKFYACK TMKQRINSLE HANNLREVQA MKRLSPHANI 60

IQLHELIFDK ETGTVSLICE LMEMNIYEFI QGRQTPLSDN TVKNYMYQLC RSLEHMHSCG 120

IFHRDVKPEN ILIKQNGLKL GDFGSCRSVH SKPPHTEYIS TRWYRAPECL LTDGYYGLKM 180

DMWSAGCVFF EIMSLSPLFP GTNELDQVAK IHDVLGTPDL TILQKLKHSR AMLYNFPPKK 240

GSGISRLVPH CPGPALSLLY QMLAYDPDER ITAETAMRHT YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013