EKS-GAA-00114

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00114

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	414.0	6.5E-124	2305	2630	326

Status

Unreviewed

Ensembl Protein

ENSGACP00000014322

UniProt Accession

G3P9P8;

Protein Name

Protein Synonyms/Alias

Gene Name

ATR

Gene Synonyms/Alias

ATR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000010787	ENSGACP00000014322	ENSGACT00000014347

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

2655

Protein Sequence
(FASTA)

TVTMEGLEMS AMIPALQELA SACAAEYDQA VQKPRQILCQ FIDRILTDVD AVALGLNKKS 60

SSEPACVMLL DFVQHIIKSS SLMFANPACQ PAQYPDATQS CADFSKWVAV RLLRVAAAPD 120

CDVVHGRVAA VLCSLLHTLR ARASFIFSLL VQELIHLARD LSGILHTHVT TLAGSGHTLD 180

IRPSTRWPAP LERFIISRRC AFSYLTPSPL VLSSPADLES LSAVTIGVVT DALRGVVSRR 240

DVSAAWETAC SFLANGNSRL RKRSMAMLSR LVELGGFPET QGHEFFAAYL HLLGTHAYAR 300

TTDANVDEKQ PYDGELLRLT RCVFQSSGVS HFEPVHLSQM FECVCALGGS DVKLGSEVTE 360

SLCLLFSFLL SVAAIYESAA LLRRQRVTEV CRTLARTVGT EAQAECAEGF LQAALRAETA 420

VVMQKSGDGE TAAKRPCNSA TKSVSKTTKT AADEVDMRVG SEVWAVANTR LEELLTFLNS 480

DGPETQRTLC ALEGLALVLH LAARCSSRAF MAAVTEVLYI ISYISNTLLC NLVDRPSPLL 540

WVPTETLGRA LKSCQSVLEG GPVPDSNRGY FHSALGTTVR VLDSILYLNI NSDGEDGLQR 600

RVCALLSLPW VCESKSVSAF KGSGFPAWLP ALAKRLGFCY SPEFRAECVS LLALQRRGVC 660

ETWRVCVFSK TLLCQDEAVR AAAVKAFPLL LHHLGNSHHN LIATSLLPRM EDGSERVKKE 720

LARIVGQLSC IQSEVSQLSA SHTVSARTPE ILCHRLSLAA EHSGKTFPSL GATVVRPFLP 780

LLEQQAPSSG KQAFLEALPH LCQHVKLVGD DGDSQAVLCA LIGLMEDSDA VVRTRFSQSV 840

RFLLTETTRN SEHGSLSESK LLVTRLKEAF NSAKLKRDDD LRNTLILTTG EIGRASQGSL 900

VSFSLLRLLH CLLSKSSPVS VAAYAQIRAL ATAKGLKLQT LFSQYKNPIC QFLVESLHSR 960

HGSALRGTPD QGKESANQRE LALDILAQIA HAFDFPDLHR FLTRTLQVLL PYLAAKASST 1020

GSALIRTLAN ELKANRREIL INNFKYIFSH LVCSCTKEEL ERAFHYLQSE TEIELGSLLR 1080

QDFQGLHNEL LLRLGEHYQQ VFNGLAILAS FATNDDPYQG PRDITSPERM ADYLQPKLLG 1140

ILAFFNMQLL SSGAGEKDRK KLALTSVMAL MRLMGSKHIS SVRVKMMTTL RTGLRYREDF 1200

PLLCCQTWDC FVRSVETAHL GPLLSHVIVA LLPLIPLQPK ETAAIIRFLI LENREEVNDY 1260

LHEIYFLPDH PELKIHTVLQ NYKKLTASSS DLAAALQLSM RAVQHENVDV RVHALTSLRN 1320

MMHSKQKWLL RQVCASEAVE PVISSLVSVL LKGCQDSSPE ARLLCGECLG ELGAVDPGRL 1380

DLSHTQTHGD RNTFVSGVDD PNFAYDLLNE LTRTFLAYAD DVRAQDSSAY AIQELLSIFE 1440

CREGRLDTAG RRLWRRFPEQ IQEILEPHLN SRYKSSQKEV NWSKLKKPVY LSKRGSKFSD 1500

WSATWAGYLI SKVRHELASK VFTCCSFIIK HDYKVTIYLL PHILLYMLLG CTPAEQQEVT 1560

EEMLAVLTAE DGRGGGPGQE TASSLSQLST QTVFSMFSHL TQCSRHFLYS KPKHSGESHP 1620

GHKSLASGFV TTESGDYQRV VAFLKGIPQD VLAKASLRSN AFTRALMHFE AYILENKEDI 1680

QDHLTFLQTL YAAMHEPDGV RGVNAVRREE PSLREQILEH ESIGLLRDAT ACYDRAIQLE 1740

SDQIGHYHGV MTSMLGLGQL STVITQVNGV LASKHQWKSE LNTYRVEAAW KLGKWDLLEE 1800

YLSSDPQSNT WGVRLGQLLL SAKKQDAETF YDRLKLVRKE QIVPLSAASY ECGTYQRGYE 1860

YIVRLHMLSE LEHSFTELQK QRECSTPGPT HLPPHWSDRL EMTQNSFRAK EPVLALRRSL 1920

LSLGPQQKSK ALVGECWLQS ARVARKAGHH QTAFNALLNA EHTHLAELVT EKAKWLWSKG 1980

DVHEALIVLQ KGVAQCFPHD QPLTEPRSLQ TKSKAMLLVG RFMEETANFE SNAIMKAYKD 2040

VTNLLPEWED GNFYLAKYYD KVMPMVTDNK LEKQGNLIRY IVTYFGKALQ FGNQYIYQAM 2100

PRMLSLWLDF GAKVCECEKD TAGRADRPMR QELGKINTVM SEHCANLAPY QFLTAFSQLI 2160

SRVCHSSDEV FNVLMKIVAK VFLAYPQQAM WLMAAVSKSS YPMRMNRCNQ ILKKAISLKQ 2220

SLEKFIGDAN RLTDKLLELC NKPVDGSSST LSMSVHFKQL KRLVEEPTFS QILIPLQSVL 2280

IPTLPSTGGA NTQHDAFPGH WAYLSGFDDN VEILASLQKP KKISLKGSDG RSYTMMCKPK 2340

DDLRKDCRLM EFNCLINKCL RKDAESRRRE LHIRTYAVIP LNEECGIIEW VNNTAGLRHI 2400

LTKLYKERGI YLSGKELRKL ILPKTAPFEE KLRIHKEVLC VRHLPIFHEW FLRTFPDPTS 2460

WYSSRSAYCR STAVMSMVGY ILGLGDRHGE NILFDSFTGE CVHVDFNCLF NKGETFDVPE 2520

VVPFRLTQNM VHAMGPMGIE GLFRQACEVT LRLMRDQREP LMSVLKTFLH DPLVEWSKQA 2580

KGLSKAQANE TGEIVNEKAK TLVCDIDQRL QGVIKSRNKV LGLPLSIEGH VHYLIQEATD 2640

DKLLCQMYLG WGPYL 2655

Nucleotide Sequence
(FASTA)

ACTGTAACAA TGGAAGGACT GGAGATGTCT GCGATGATAC CGGCTCTCCA GGAGCTAGCG 60

AGCGCCTGCG CGGCTGAGTA CGACCAGGCG GTGCAGAAAC CGCGACAGAT CCTCTGTCAG 120

TTCATCGACA GGATCCTGAC GGATGTGGAT GCTGTCGCTC TAGGGCTGAA TAAGAAGTCC 180

AGTTCGGAGC CGGCCTGTGT GATGCTGCTG GACTTTGTGC AACATATAAT CAAATCCTCG 240

TCGCTGATGT TCGCCAACCC TGCCTGCCAG CCCGCCCAGT ACCCGGACGC CACGCAGAGC 300

TGTGCTGACT TCAGTAAGTG GGTCGCTGTC CGTTTGCTTC GCGTGGCGGC CGCCCCGGAC 360

TGTGACGTCG TCCACGGGCG GGTCGCCGCT GTGCTGTGCT CTTTGCTTCA CACTCTGAGA 420

GCCAGGGCCT CGTTCATCTT CAGCCTCCTC GTTCAGGAGC TGATTCATTT GGCCCGGGAC 480

CTCAGCGGCA TCCTGCACAC CCATGTTACC ACGCTGGCAG GAAGTGGACA CACTTTGGAC 540

ATCCGACCAT CGACCCGGTG GCCCGCGCCT CTCGAGCGTT TCATTATCTC CCGCCGCTGC 600

GCCTTCTCGT ACCTCACCCC GTCTCCGCTC GTCCTCTCCT CGCCGGCCGA CCTGGAGTCG 660

CTGAGCGCCG TGACGATCGG CGTCGTCACC GACGCGCTGC GGGGAGTCGT CTCCCGTCGG 720

GACGTCAGCG CGGCCTGGGA GACGGCGTGC TCCTTCCTGG CCAATGGCAA CAGCAGGTTG 780

AGGAAGCGCT CCATGGCGAT GCTGAGCAGA CTCGTGGAGC TGGGAGGCTT CCCCGAGACG 840

CAGGGCCACG AGTTCTTCGC AGCCTACCTT CACCTGCTGG GAACGCACGC CTACGCGCGC 900

ACTACGGACG CGAACGTGGA TGAGAAACAG CCGTACGACG GAGAGCTGCT GCGCCTGACC 960

CGCTGCGTGT TCCAGTCGTC CGGTGTCTCT CACTTTGAGC CCGTCCACCT CTCGCAGATG 1020

TTCGAGTGCG TCTGCGCCCT CGGAGGCTCC GACGTCAAAC TGGGCTCTGA GGTCACCGAA 1080

TCCCTCTGCC TGCTGTTCAG CTTCTTGCTG TCGGTGGCCG CGATTTATGA AAGCGCCGCC 1140

TTGTTAAGGA GGCAGCGAGT CACAGAGGTC TGCAGGACGC TGGCACGCAC CGTTGGAACA 1200

GAAGCTCAGG CTGAATGCGC CGAGGGGTTT CTTCAAGCCG CACTGAGGGC TGAGACCGCT 1260

GTGGTGATGC AGAAGTCTGG AGATGGAGAG ACCGCTGCAA AGAGACCCTG CAACTCTGCC 1320

ACCAAGTCGG TCAGCAAAAC AACAAAAACA GCAGCTGACG AGGTGGACAT GCGCGTTGGC 1380

AGCGAGGTTT GGGCTGTGGC GAACACTCGT CTGGAGGAAC TGCTGACTTT TTTGAACTCC 1440

GACGGCCCGG AAACCCAACG GACTCTGTGT GCTCTGGAGG GTCTGGCCCT CGTCCTCCAC 1500

CTGGCAGCTC GGTGTAGCTC ACGGGCATTT ATGGCCGCTG TCACTGAAGT TCTATATATA 1560

ATCTCTTATA TATCCAATAC ATTACTATGT AACTTGGTTG ACAGACCGTC TCCTCTTCTC 1620

TGGGTGCCCA CTGAGACTTT GGGAAGGGCG CTGAAGAGCT GCCAGTCAGT TTTAGAAGGA 1680

GGTCCTGTTC CCGACTCAAA CCGCGGCTAC TTTCACTCTG CTTTAGGGAC CACAGTTAGA 1740

GTCCTGGACT CCATCCTCTA CCTGAACATA AACAGCGACG GCGAGGACGG GCTCCAGCGG 1800

CGTGTGTGTG CTCTGCTGTC TCTTCCGTGG GTGTGTGAGA GCAAGTCCGT CTCAGCCTTC 1860

AAGGGTTCAG GATTCCCCGC CTGGCTGCCC GCCTTGGCTA AAAGACTCGG CTTCTGTTAC 1920

TCGCCGGAGT TCCGGGCCGA GTGCGTGTCG CTGCTGGCCC TTCAGCGCCG CGGCGTGTGC 1980

GAGACGTGGC GCGTGTGCGT GTTCTCCAAG ACGTTGCTGT GCCAAGACGA GGCGGTGAGA 2040

GCGGCGGCGG TCAAGGCCTT CCCTCTTCTG CTTCACCACC TTGGAAACTC TCACCACAAC 2100

CTCATCGCCA CTTCCCTGCT TCCCAGGATG GAGGACGGCT CGGAGCGGGT GAAGAAGGAG 2160

CTTGCCAGGA TAGTCGGTCA GCTGAGCTGC ATCCAATCGG AGGTCTCCCA GCTCAGCGCC 2220

AGCCACACAG TGTCCGCTCG CACTCCTGAG ATCCTCTGCC ACCGGCTCAG CCTTGCAGCG 2280

GAGCATTCTG GGAAGACTTT TCCTTCCCTC GGGGCGACTG TTGTCAGACC CTTCCTGCCG 2340

CTGCTTGAGC AGCAAGCTCC GAGCAGCGGT AAACAAGCGT TCCTAGAAGC TCTGCCTCAT 2400

CTCTGCCAGC ATGTGAAACT GGTGGGTGAC GACGGCGACT CTCAGGCGGT TCTCTGTGCT 2460

CTCATTGGTC TCATGGAAGA CTCGGACGCA GTGGTCAGAA CGCGCTTCAG CCAATCGGTG 2520

CGTTTCCTGC TGACGGAGAC CACCAGGAAC TCCGAGCACG GCTCTCTGAG CGAGTCTAAG 2580

CTCCTGGTCA CCCGTCTTAA AGAGGCGTTC AACAGCGCTA AACTCAAAAG GGACGACGAC 2640

CTGCGCAACA CTCTGATCCT CACCACCGGG GAGATCGGCA GAGCGTCTCA GGGAAGTCTG 2700

GTGTCGTTCT CTCTGCTGCG GCTGCTCCAC TGTCTGCTGT CCAAGTCGTC CCCGGTGTCC 2760

GTAGCTGCTT ACGCTCAGAT CCGAGCTCTG GCCACCGCCA AAGGTCTTAA ACTGCAAACC 2820

CTCTTCAGTC AGTACAAGAA CCCAATTTGC CAGTTCCTGG TGGAGTCGCT GCATTCTCGT 2880

CACGGGTCGG CCCTGCGAGG CACGCCGGAT CAGGGCAAAG AATCGGCCAA TCAGAGAGAG 2940

CTTGCTCTGG ACATCCTGGC TCAGATCGCA CACGCTTTTG ATTTCCCAGA CCTCCACCGC 3000

TTCCTCACTA GGACCCTGCA GGTGCTCTTG CCCTACCTGG CAGCGAAAGC GAGCTCGACA 3060

GGCTCCGCCC TCATCCGCAC CCTGGCCAAT GAGCTGAAGG CAAACAGGAG AGAGATCCTG 3120

ATCAACAACT TCAAATACAT CTTTAGCCAC CTGGTGTGTT CCTGCACTAA AGAAGAGCTA 3180

GAGAGGGCCT TCCACTACCT GCAGAGTGAG ACAGAGATCG AACTGGGCTC TCTGCTCAGG 3240

CAGGACTTCC AGGGTCTTCA CAACGAGCTG CTGCTGCGCT TGGGAGAGCA CTACCAACAG 3300

GTGTTTAATG GGCTCGCTAT CCTGGCGTCC TTTGCAACCA ATGATGACCC GTACCAGGGT 3360

CCCCGAGACA TCACCTCTCC AGAACGAATG GCGGACTACC TGCAGCCGAA GCTGCTGGGA 3420

ATTCTTGCCT TCTTCAACAT GCAGCTGCTC AGCTCCGGCG CGGGAGAGAA GGACCGCAAA 3480

AAGTTGGCTC TGACCAGTGT GATGGCTCTA ATGCGACTCA TGGGCTCCAA ACACATCAGC 3540

TCGGTGCGGG TAAAGATGAT GACGACGCTC CGCACGGGTC TCCGATACAG AGAGGACTTC 3600

CCTCTGCTCT GCTGCCAGAC GTGGGATTGT TTTGTGAGGA GCGTGGAGAC GGCCCACCTG 3660

GGACCTCTAC TGAGTCATGT TATTGTTGCC CTCCTGCCTC TGATCCCGCT GCAGCCCAAA 3720

GAAACTGCTG CCATCATCCG CTTCCTAATA CTGGAAAACA GGGAGGAAGT CAACGACTAC 3780

CTTCATGAGA TTTACTTTCT GCCAGACCAC CCAGAGCTGA AGATCCACAC GGTTCTGCAG 3840

AACTACAAGA AGCTGACAGC CAGCAGCAGC GACTTGGCCG CGGCGCTGCA GCTCTCCATG 3900

AGGGCGGTGC AACACGAAAA CGTTGACGTC AGGGTTCATG CGCTGACCAG CCTCAGGAAC 3960

ATGATGCACA GCAAGCAGAA GTGGCTGCTG CGTCAGGTCT GTGCGAGTGA AGCGGTGGAG 4020

CCGGTCATCT CCAGCTTGGT GTCGGTGCTG CTGAAGGGCT GCCAGGACTC GTCCCCGGAG 4080

GCCAGGCTCC TCTGCGGGGA GTGTCTCGGG GAGCTGGGGG CCGTAGATCC TGGACGTCTG 4140

GATCTGTCAC ACACTCAAAC GCATGGCGAC CGCAACACCT TTGTGAGTGG AGTCGATGAT 4200

CCCAACTTTG CCTACGACCT GCTTAATGAA CTGACCAGAA CGTTCCTGGC TTACGCTGAT 4260

GATGTGAGAG CACAGGACTC TTCTGCCTAT GCAATCCAGG AGCTGCTGTC CATCTTTGAG 4320

TGTCGTGAGG GTCGATTAGA CACAGCAGGG CGCCGGCTGT GGAGGAGATT CCCAGAGCAG 4380

ATTCAAGAAA TATTGGAACC ACACCTCAAC AGCAGGTATA AGAGCAGTCA AAAGGAGGTA 4440

AACTGGTCCA AGCTAAAGAA GCCGGTGTAC TTAAGCAAGA GAGGCAGCAA ATTCTCTGAT 4500

TGGTCAGCCA CCTGGGCTGG ATACCTCATC AGCAAGGTGA GACACGAGCT GGCCAGCAAA 4560

GTGTTCACCT GCTGCAGCTT CATCATCAAA CACGACTACA AGGTCACAAT CTACCTGCTG 4620

CCTCATATTC TGCTCTACAT GCTGCTGGGC TGCACACCTG CAGAGCAACA GGAGGTAACG 4680

GAGGAGATGC TGGCCGTGCT GACAGCGGAG GACGGTCGAG GAGGCGGGCC CGGTCAGGAG 4740

ACGGCCTCCA GCCTGTCACA GCTCAGCACT CAAACCGTCT TCAGCATGTT TTCTCACCTC 4800

ACACAGTGTA GCCGCCACTT CCTCTACTCC AAACCCAAAC ACAGCGGTGA GTCACACCCA 4860

GGGCATAAAT CTCTGGCGTC TGGGTTTGTA ACCACGGAGA GCGGCGACTA CCAGCGGGTG 4920

GTGGCCTTCC TCAAGGGTAT TCCACAGGAC GTCCTGGCCA AGGCTTCTCT GCGATCCAAC 4980

GCGTTCACTC GCGCCCTCAT GCACTTTGAA GCATACATCT TAGAAAACAA AGAGGACATC 5040

CAGGACCATC TCACCTTCTT GCAGACTCTC TATGCCGCCA TGCATGAGCC CGATGGAGTG 5100

AGGGGGGTCA ACGCAGTAAG GAGGGAGGAG CCGTCGCTAC GTGAGCAGAT ACTGGAGCAT 5160

GAGAGCATCG GCCTGCTGCG AGACGCAACC GCCTGCTATG ACCGGGCCAT TCAGCTGGAG 5220

TCGGACCAGA TCGGTCACTA TCACGGGGTG ATGACCTCTA TGCTCGGCCT GGGACAACTG 5280

TCAACTGTCA TCACTCAGGT CAATGGAGTA CTGGCCAGCA AGCATCAGTG GAAGTCGGAG 5340

CTGAACACCT ACAGAGTGGA GGCCGCCTGG AAGCTCGGAA AATGGGACCT GCTCGAAGAG 5400

TATTTGAGTT CAGACCCCCA GTCCAATACC TGGGGGGTGC GACTTGGCCA GTTACTGCTG 5460

TCCGCTAAGA AGCAGGATGC CGAGACTTTC TATGACAGGC TGAAGCTGGT GAGGAAGGAA 5520

CAGATTGTCC CTCTGTCTGC AGCCAGTTAT GAGTGTGGCA CCTACCAGAG AGGATACGAG 5580

TACATCGTCA GGCTCCACAT GCTCAGCGAG TTGGAACACA GTTTTACTGA GCTGCAGAAA 5640

CAGAGGGAAT GCTCCACCCC CGGCCCCACT CACCTGCCTC CTCATTGGTC CGATCGCCTG 5700

GAGATGACCC AAAATTCCTT CAGGGCCAAG GAACCGGTCC TGGCCCTCCG CCGTTCCCTG 5760

CTCAGCTTGG GACCACAGCA AAAGAGCAAA GCGCTGGTCG GCGAGTGCTG GCTGCAAAGC 5820

GCCCGTGTGG CCAGAAAGGC AGGACACCAC CAGACTGCCT TCAATGCACT ACTGAACGCA 5880

GAGCACACAC ACCTGGCCGA GCTGGTGACC GAGAAGGCCA AGTGGCTTTG GTCCAAGGGC 5940

GACGTGCACG AGGCCCTCAT CGTCCTGCAG AAGGGCGTGG CCCAGTGTTT CCCCCACGAC 6000

CAGCCGCTCA CAGAGCCTCG CAGCCTGCAG ACCAAGAGCA AGGCCATGCT GCTGGTGGGA 6060

CGCTTCATGG AGGAGACGGC CAACTTTGAG TCCAACGCCA TCATGAAGGC GTACAAGGAT 6120

GTTACCAACC TTCTGCCTGA GTGGGAGGAT GGAAACTTCT ACCTGGCCAA GTATTACGAC 6180

AAAGTGATGC CAATGGTGAC TGATAACAAG CTGGAGAAAC AGGGGAACCT CATCCGATAT 6240

ATCGTAACAT ACTTTGGAAA AGCCTTGCAG TTTGGAAACC AGTACATCTA CCAGGCCATG 6300

CCTCGCATGC TGTCTCTCTG GCTGGATTTT GGAGCCAAAG TGTGTGAGTG TGAGAAAGAC 6360

ACAGCGGGGC GAGCAGATAG ACCGATGCGA CAGGAGCTGG GAAAAATCAA CACGGTGATG 6420

AGCGAGCACT GTGCCAACTT GGCGCCGTAC CAGTTCCTGA CCGCCTTCTC CCAGCTCATC 6480

TCCAGGGTCT GCCATTCCAG CGACGAGGTC TTCAACGTCC TCATGAAAAT CGTGGCCAAA 6540

GTCTTCCTGG CGTACCCACA ACAGGCCATG TGGCTAATGG CCGCTGTCTC CAAGTCTTCC 6600

TATCCGATGC GTATGAACCG TTGTAATCAG ATCCTTAAGA AAGCAATTAG TCTTAAACAG 6660

TCTCTGGAGA AATTCATTGG AGATGCCAAC AGGTTGACCG ACAAGCTGCT GGAGCTCTGC 6720

AACAAGCCGG TGGATGGAAG CAGCAGCACC CTCAGCATGA GCGTTCACTT CAAGCAGCTA 6780

AAACGTCTGG TGGAGGAGCC GACCTTCAGC CAGATCCTGA TCCCACTGCA GTCGGTCCTC 6840

ATCCCAACGC TGCCGTCTAC CGGCGGGGCA AACACGCAGC ACGACGCTTT CCCCGGACAC 6900

TGGGCCTACC TGAGCGGGTT TGATGACAAT GTGGAGATCT TGGCCTCCTT ACAGAAGCCT 6960

AAGAAGATAA GCCTGAAGGG TTCAGATGGG CGGAGCTACA CCATGATGTG TAAACCTAAA 7020

GATGACCTGA GGAAGGACTG CAGACTCATG GAGTTCAACT GCCTCATAAA CAAGTGCCTA 7080

CGTAAAGATG CTGAGTCACG GCGGAGGGAG CTGCACATCC GCACCTACGC TGTGATTCCT 7140

CTCAATGAGG AGTGCGGCAT CATCGAATGG GTCAACAACA CCGCTGGACT TCGACACATA 7200

CTCACCAAGC TGTATAAAGA GAGAGGCATC TACTTATCAG GTAAAGAGCT CCGGAAGCTT 7260

ATTCTTCCGA AGACGGCCCC CTTTGAGGAG AAGCTACGAA TCCACAAGGA GGTGCTTTGC 7320

GTTCGACACC TTCCTATATT CCACGAGTGG TTCCTCCGGA CCTTCCCCGA CCCTACATCA 7380

TGGTACAGCA GTCGCTCCGC GTACTGCCGC TCCACTGCCG TGATGTCCAT GGTGGGCTAC 7440

ATCCTGGGTC TGGGCGATCG CCACGGGGAA AACATCCTCT TTGACTCTTT CACTGGGGAA 7500

TGTGTTCATG TCGACTTCAA CTGCCTGTTT AACAAGGGGG AGACCTTCGA TGTGCCAGAA 7560

GTGGTTCCCT TCCGTCTGAC CCAGAACATG GTCCACGCTA TGGGCCCCAT GGGCATCGAG 7620

GGCCTCTTCA GGCAGGCCTG TGAGGTCACC TTGAGACTAA TGCGGGACCA AAGGGAACCG 7680

CTCATGAGTG TGCTGAAGAC CTTCCTTCAT GACCCCCTGG TGGAGTGGAG CAAACAAGCC 7740

AAAGGACTTT CAAAAGCTCA GGCCAATGAG ACGGGAGAGA TCGTCAATGA AAAGGCGAAA 7800

ACCCTCGTGT GTGACATCGA CCAGCGTCTG CAGGGAGTCA TAAAGAGCAG GAACAAAGTG 7860

CTGGGTCTAC CTCTGTCCAT AGAGGGACAC GTCCACTACC TCATACAGGA AGCAACAGAC 7920

GACAAACTGC TCTGTCAGAT GTATCTGGGC TGGGGGCCCT ACCTGTAG 7968

Domain Profile

S: 2     agfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdk  61

          gfd++veilas+qkpkk++l+Gsdg++y +++k+k+Dlr+d+r+++++ l+N++L+kd+

Q: 2305  SGFDDNVEILASLQKPKKISLKGSDGRSYTMMCKPKDDLRKDCRLMEFNCLINKCLRKDA  2364

         58**********************************************************

S: 62    etsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdls  121

         e++rr+L+irty+V+pl++++g+iewv+nt++L+++l+kl+++++++l+         ++

Q: 2365  ESRRRELHIRTYAVIPLNEECGIIEWVNNTAGLRHILTKLYKERGIYLS--------GKE  2416

         ************************************************7........778

S: 122   tvqarkpklkhlklslevfkevlenlv.pkdllkklllekfpspeewfelrkaytrslAv  180

          ++   pk++   ++l + kevl  ++ p  ++++++l++fp+p++w+++r+ay+rs+Av

Q: 2417  LRKLILPKTAPFEEKLRIHKEVLCVRHlP--IFHEWFLRTFPDPTSWYSSRSAYCRSTAV  2474

         88888899999999999*****9988845..*****************************

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe vPFRLT+n+v a

Q: 2475  MSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGET-FDVPEVVPFRLTQNMVHA  2533

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce +lr++r+++e l+++L++fl+dplv+w+k     +k++ +et+e

Q: 2534  MGPMGIEGLFRQACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKqakglSKAQANETGE  2593

         *************************************************99*********

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

          ++ekak+   +i ++l++v k++n+v  ++l+++++

Q: 2594  IVNEKAKTLVCDIDQRLQGVIKSRNKVLGLPLSIEGH  2630

         *******************************999987

Domain Sequence
(FASTA)

SGFDDNVEIL ASLQKPKKIS LKGSDGRSYT MMCKPKDDLR KDCRLMEFNC LINKCLRKDA 60

ESRRRELHIR TYAVIPLNEE CGIIEWVNNT AGLRHILTKL YKERGIYLSG KELRKLILPK 120

TAPFEEKLRI HKEVLCVRHL PIFHEWFLRT FPDPTSWYSS RSAYCRSTAV MSMVGYILGL 180

GDRHGENILF DSFTGECVHV DFNCLFNKGE TFDVPEVVPF RLTQNMVHAM GPMGIEGLFR 240

QACEVTLRLM RDQREPLMSV LKTFLHDPLV EWSKQAKGLS KAQANETGEI VNEKAKTLVC 300

DIDQRLQGVI KSRNKVLGLP LSIEGH 326

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013