EKS-GAA-00442

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00442

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Lmr	472.5	4.7E-142	133	406	274

Status

Unreviewed

Ensembl Protein

ENSGACP00000014399

UniProt Accession

G3P9X5;

Protein Name

Protein Synonyms/Alias

Gene Name

AATK (2 of 2)

Gene Synonyms/Alias

AATK (2 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000010878	ENSGACP00000014399	ENSGACT00000014425

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

1231

Protein Sequence
(FASTA)

MCFALHVIVM SSAFFNPSFA FSSHFDTDGA PLSELSWPSS LAVVAVSFSG LFTFVFLMLA 60

CLCCKKGDVG FKEFENTEGE EYQADLSALA SPSSQNGPEV YILPLTEVSL PVSKQPGRSI 120

QLLKSSDLGR HSLLYLKEIG HGWFGKVLLG EVNAGLSTTQ VIVKELKASA SVQDQMQFLE 180

EAQPYRTLQH SALLQCLAQF SEVTPYLLVM EFCPMGDLKS YMRSCQVADS EMPEPLILQR 240

MVCDIASGLV QLHKYNFIHS DLALRNCLLT SEMSVKIGDY GLSQSRYKDD YYVTQDQMWV 300

PLRWIAPELI DEVHGNLLVV DQTKSSNIWS LGVTLWELFE LGNQPYRHYS DRQVLTYAVK 360

EQQLKLPKPL LQFPLAERWY EVMQFCWLQQ ELRPSSEEVH LLVTYLCAKG SSEAEEDFEQ 420

RWNTLRPNLF GSTSHTAAAE VLTHAPASSD ILSPEQTQTV ELASSASSSF PLLEHFSDGL 480

HSDTGDDLLT VTETSHGLNF EYKWEQGRAE QPYCASSTSG ALGQGNPYYQ DIYYSSTSPS 540

YYEPEHPGVV PVLSAQSPSV GSEYYIRIEE PMDCNINLDD TEVDCSPGLK ASCSQLSSES 600

QNDSSPTVQL SMEPLLRQSS PVETTQSTVN GHQHTRPATP VRLNRLHPQI PDQTLSTLLA 660

GFCDPYLEAV TGRSAVNDDG VLVGQQRGDD IEDDLFSEGE STNWTSNHSA NNNSLSFDSR 720

QTGSGHDGYL ELQNTAHPNT TELFSLTKAT TRTFHSSRFC DTSETEDSGC NAASKPSKLG 780

SYMNLCHKEI EEATTQLGND STTEHLRSMY TLTSSSINGE RLYSEPKMIP EANTSESSRI 840

LDGGMGIRNS SISLVGLGDF SEDDDDDITD ITSGIFADFN LDYADIDEEE LSPLKHPERT 900

PDCADTLNRS SSMASPSNQA FSPDPFNIPV LPKSLDSGYD TENNESPEFF FKELGDPLGE 960

ERSLRLGGEP ELVLQIKSLN DKNAYRDSAY FSDYDAENER SPQEKGSGFL SGPSICDFPA 1020

EKSSPIKVDH MVKRLLNQKH VTESFVLVNH LEPDHDSHHR LPTPGLSMLS PFPPQMGGCL 1080

TKESAPAKLN SSIGSGPSST AQEASGNHDQ ESSGPVNLSS SSSLLELCGD DVRAPLEEAE 1140

DEDDSDDSES DEELRTYNIQ DEESEESEDD LTLVPVVVSD SSRARHLRSL LKMPTLLTQS 1200

FCDELEGNKK AVSFFDDVTV FLFDQESPTG E 1231

Nucleotide Sequence
(FASTA)

ATGTGCTTTG CCCTACATGT GATTGTCATG TCTTCGGCAT TTTTCAATCC CAGTTTTGCC 60

TTCAGCTCCC ACTTTGATAC AGATGGCGCT CCGCTGAGCG AGCTGTCATG GCCTTCGTCA 120

CTGGCAGTGG TGGCTGTCTC GTTCTCTGGA CTCTTCACCT TTGTCTTCCT CATGCTGGCC 180

TGCCTGTGTT GCAAGAAAGG GGACGTCGGC TTCAAGGAGT TTGAAAACAC AGAGGGAGAG 240

GAGTACCAGG CAGATCTCTC TGCTCTGGCC TCGCCTTCCT CCCAGAATGG CCCCGAGGTC 300

TACATCCTCC CCCTGACCGA GGTCTCCCTG CCCGTCTCCA AGCAGCCCGG CAGATCCATC 360

CAACTGCTGA AATCATCAGA CCTTGGCCGC CATAGTCTAC TCTATCTAAA GGAAATTGGA 420

CATGGCTGGT TTGGCAAGGT TCTGCTGGGT GAGGTCAACG CCGGCCTCAG CACCACCCAG 480

GTGATCGTAA AGGAGCTGAA AGCCAGTGCC AGCGTCCAGG ACCAGATGCA GTTCCTTGAG 540

GAGGCGCAGC CATACCGAAC CCTCCAGCAC TCGGCCCTCC TGCAGTGCCT GGCACAGTTC 600

TCAGAGGTCA CTCCTTATCT GCTGGTCATG GAGTTTTGCC CCATGGGTGA TCTGAAGAGC 660

TACATGCGCA GCTGTCAGGT GGCCGACTCC GAGATGCCCG AGCCTTTGAT CCTCCAAAGA 720

ATGGTGTGTG ACATCGCCTC AGGGCTTGTG CAACTCCACA AATACAACTT TATACACAGT 780

GACTTGGCCT TGCGAAACTG CCTGCTAACT TCAGAAATGT CAGTTAAGAT CGGAGACTAT 840

GGTCTTTCTC AGAGCCGGTA TAAGGATGAC TATTATGTAA CACAAGACCA GATGTGGGTG 900

CCCCTGCGCT GGATTGCACC TGAGCTCATA GACGAAGTCC ACGGAAACCT GCTGGTTGTT 960

GATCAAACAA AATCCAGCAA CATATGGTCA TTGGGGGTGA CTCTGTGGGA GCTGTTTGAG 1020

CTGGGAAACC AGCCGTACAG ACACTACTCT GACAGACAGG TGCTGACATA CGCTGTGAAG 1080

GAACAGCAGC TCAAACTTCC CAAACCCCTG CTCCAATTCC CTCTGGCTGA GCGCTGGTAT 1140

GAGGTGATGC AGTTTTGCTG GCTGCAGCAG GAGCTGAGAC CTAGCAGCGA GGAAGTCCAC 1200

CTTCTGGTCA CATACTTGTG TGCCAAAGGC TCCAGTGAGG CTGAGGAGGA CTTTGAACAA 1260

CGTTGGAATA CCTTGAGACC CAACCTGTTC GGCAGCACTT CCCACACAGC CGCAGCGGAA 1320

GTCTTGACCC ATGCACCTGC TTCGTCCGAC ATCCTTAGTC CAGAGCAAAC TCAGACAGTG 1380

GAGCTGGCCT CCTCTGCCTC GTCCTCCTTC CCCCTCCTGG AGCACTTCTC TGACGGCTTA 1440

CACTCCGACA CAGGAGATGA CCTGCTGACC GTCACAGAGA CAAGCCACGG TCTCAACTTT 1500

GAGTACAAAT GGGAGCAGGG CCGAGCCGAG CAGCCGTACT GCGCCTCCTC CACCAGTGGG 1560

GCACTGGGCC AAGGGAACCC ATATTACCAG GACATCTATT ATTCAAGTAC ATCCCCATCC 1620

TATTATGAAC CTGAACACCC CGGTGTGGTT CCAGTGTTGA GTGCCCAAAG CCCCTCGGTC 1680

GGCAGCGAGT ATTACATTCG CATAGAGGAA CCAATGGATT GTAACATTAA CCTGGACGAC 1740

ACCGAGGTGG ACTGCAGCCC AGGATTGAAG GCCAGCTGCA GCCAACTATC CTCTGAGAGT 1800

CAAAATGATT CAAGCCCCAC TGTGCAGCTA AGTATGGAGC CACTGCTGAG GCAGTCATCC 1860

CCAGTCGAGA CAACACAATC TACTGTGAAC GGTCATCAGC ATACAAGGCC CGCCACTCCT 1920

GTCCGTCTGA ACCGGCTACA TCCCCAGATT CCAGATCAAA CCTTGTCCAC CCTGTTGGCC 1980

GGGTTCTGTG ATCCCTACCT TGAAGCTGTC ACAGGCCGCA GCGCGGTTAA TGATGACGGC 2040

GTGCTGGTGG GCCAGCAGAG AGGCGACGAC ATTGAGGATG ACCTTTTCTC GGAAGGAGAG 2100

TCTACTAACT GGACATCAAA TCATTCTGCA AACAACAATA GCCTGAGCTT TGACAGCAGG 2160

CAGACAGGCA GTGGGCATGA TGGCTATCTG GAACTCCAAA ATACTGCTCA CCCTAACACA 2220

ACAGAATTAT TCTCTTTAAC CAAGGCCACC ACCAGAACCT TCCACAGCTC CAGGTTTTGT 2280

GACACCTCGG AGACAGAAGA CTCTGGTTGT AATGCCGCTA GCAAGCCCAG CAAATTAGGC 2340

TCATACATGA ACTTATGTCA CAAAGAAATA GAGGAAGCTA CCACTCAATT GGGAAATGAT 2400

TCAACTACAG AACATCTAAG GAGTATGTAT ACCCTTACCA GCTCAAGTAT TAATGGAGAA 2460

AGACTGTACT CCGAGCCGAA AATGATACCG GAGGCAAACA CATCAGAGAG CAGCAGAATA 2520

TTGGATGGTG GAATGGGGAT CAGAAACTCC AGCATAAGCT TGGTAGGGCT TGGTGACTTT 2580

AGTGAGGATG ATGATGATGA CATTACAGAT ATCACGTCTG GGATCTTTGC CGACTTCAAT 2640

CTGGACTATG CCGACATAGA CGAAGAAGAG CTCAGCCCAT TAAAGCATCC AGAGAGAACT 2700

CCTGACTGTG CAGACACCCT TAACCGGTCC TCATCGATGG CAAGCCCTTC AAATCAGGCC 2760

TTTAGCCCCG ATCCGTTCAA CATCCCTGTC CTACCCAAAT CCCTGGACAG TGGCTATGAC 2820

ACAGAGAATA ATGAATCTCC AGAGTTTTTC TTCAAAGAGC TTGGAGATCC TCTGGGTGAG 2880

GAGAGGAGCC TTAGGCTGGG TGGGGAACCA GAACTCGTTC TCCAGATAAA GAGCCTGAAT 2940

GACAAGAACG CATACAGAGA TTCAGCGTAT TTCTCAGACT ATGATGCCGA AAATGAGAGG 3000

AGCCCTCAGG AGAAAGGCAG TGGGTTCCTT TCAGGTCCCA GTATCTGTGA TTTTCCTGCA 3060

GAGAAATCCA GCCCTATCAA AGTTGATCAT ATGGTGAAAA GGCTATTAAA CCAGAAACAT 3120

GTAACTGAAA GTTTTGTTTT GGTGAATCAC TTAGAGCCTG ACCATGACTC CCACCATCGC 3180

CTGCCAACCC CCGGGTTGTC CATGCTGTCG CCATTTCCTC CACAGATGGG TGGCTGCCTG 3240

ACTAAAGAGT CTGCCCCTGC AAAGCTTAAC TCCTCCATTG GGTCTGGGCC GTCTTCCACT 3300

GCCCAGGAGG CTTCAGGGAA CCATGATCAG GAATCCAGTG GCCCTGTCAA CCTGTCCTCT 3360

TCCTCGTCGT TGTTGGAGCT GTGCGGAGAT GATGTGAGAG CGCCACTGGA AGAGGCGGAG 3420

GATGAAGATG ATTCGGATGA CAGTGAGTCT GATGAAGAGT TGAGGACCTA CAACATCCAA 3480

GATGAAGAGA GTGAGGAGAG TGAGGATGAT TTGACCCTGG TGCCCGTGGT GGTAAGCGAC 3540

AGCAGCAGGG CCAGACACCT ACGTAGTCTC CTGAAGATGC CCACACTGCT TACCCAGTCC 3600

TTCTGTGATG AGTTGGAGGG GAATAAAAAA GCAGTGTCCT TTTTTGATGA TGTCACAGTG 3660

TTCCTTTTTG ACCAGGAGAG TCCCACCGGA GAG 3693

Domain Profile

S: 1     lsylkeigsgwfgkvllgevfsdvssaqvvvkelkasaspkeqrkfleeaqpyralqhpn  60

         l ylkeig+gwfgkvllgev++++s++qv+vkelkasas+++q++fleeaqpyr+lqh+

Q: 133   LLYLKEIGHGWFGKVLLGEVNAGLSTTQVIVKELKASASVQDQMQFLEEAQPYRTLQHSA  192

         78**********************************************************

S: 61    vlqclgqcvealpyllvlefcdlgdlkaylraereaeslspdlrtlqrmalevaaglahl  120

         +lqcl+q  e++pyllv+efc++gdlk+y+r++++a s  p++++lqrm +++a+gl++l

Q: 193   LLQCLAQFSEVTPYLLVMEFCPMGDLKSYMRSCQVADSEMPEPLILQRMVCDIASGLVQL  252

         ************************************************************

S: 121   hklnyvhsdlalrnclltsdltvkvgdyglahskykedylltadklvvplrwaapelvde  180

         hk+n++hsdlalrncllts+++vk+gdygl+ s+yk+dy++t+d+++vplrw+apel+de

Q: 253   HKYNFIHSDLALRNCLLTSEMSVKIGDYGLSQSRYKDDYYVTQDQMWVPLRWIAPELIDE  312

         ************************************************************

S: 181   lhdrllvvdqtkesnvwslgvtlwelfelgaqpyrklsdeevlafvvreqdvklakprlk  240

         +h++llvvdqtk+sn+wslgvtlwelfelg qpyr++sd++vl+++v+eq++kl+kp l+

Q: 313   VHGNLLVVDQTKSSNIWSLGVTLWELFELGNQPYRHYSDRQVLTYAVKEQQLKLPKPLLQ  372

         ************************************************************

S: 241   lpysdrwyevlqfcwlppekrpaaedvhllltyl  274

          p+++rwyev+qfcwl+ e rp++e+vhll+tyl

Q: 373   FPLAERWYEVMQFCWLQQELRPSSEEVHLLVTYL  406

         *********************************8

Domain Sequence
(FASTA)

LLYLKEIGHG WFGKVLLGEV NAGLSTTQVI VKELKASASV QDQMQFLEEA QPYRTLQHSA 60

LLQCLAQFSE VTPYLLVMEF CPMGDLKSYM RSCQVADSEM PEPLILQRMV CDIASGLVQL 120

HKYNFIHSDL ALRNCLLTSE MSVKIGDYGL SQSRYKDDYY VTQDQMWVPL RWIAPELIDE 180

VHGNLLVVDQ TKSSNIWSLG VTLWELFELG NQPYRHYSDR QVLTYAVKEQ QLKLPKPLLQ 240

FPLAERWYEV MQFCWLQQEL RPSSEEVHLL VTYL 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF07714

; Pkinase_Tyr; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013