EKS-GAA-00521

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00521

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	529.9	1.7E-159	88	345	258

Status

Unreviewed

Ensembl Protein

ENSGACP00000014552

UniProt Accession

G3PAD3;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK1

Gene Synonyms/Alias

SGK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000010973	ENSGACP00000014552	ENSGACT00000014578
ENSGACG00000010973	ENSGACP00000014557	ENSGACT00000014583
ENSGACG00000010973	ENSGACP00000014554	ENSGACT00000014580

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

421

Protein Sequence
(FASTA)

LRPPKRSFFA SSASRAFMKQ RRMGLNDFIQ RLATNSYACK HPEVQSILNL SPPQDAELMN 60

TNPSPPPSPS QQINLGPSSN PSAKPNDFHF LKVIGKGSFG KVLLARHRAD DQFYAVKVLQ 120

KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHYSFQTAD KLYFILDYIN GGELFYHLQR 180

ERCFLEPRAR FYSAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIILTD FGLCKENIEP 240

NGTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR NTAEMYDNIL 300

NKPLQLKPNI SNAARHLLEG LLQKDRTKRL GCADDFIEIK SHVFFSPINW DDLNAKKITP 360

PFNPNVTGPN DLRHFDPEFT DEPVPSSIGC SPDSALVTAS IKDAAEAFVG FSYAPSMDSY 420

L 421

Nucleotide Sequence
(FASTA)

CTCCGCCCCC CGAAAAGAAG TTTTTTTGCC TCAAGCGCGT CGCGAGCTTT TATGAAACAG 60

AGGAGAATGG GTCTGAACGA CTTCATTCAG CGGCTCGCCA CAAACTCCTA CGCCTGCAAG 120

CATCCTGAAG TTCAGTCTAT TCTGAACTTA AGTCCTCCTC AGGATGCTGA GCTGATGAAC 180

ACAAATCCCT CTCCTCCTCC CAGTCCCTCC CAACAGATCA ACCTCGGACC ATCCTCCAAC 240

CCTTCAGCCA AACCCAACGA CTTCCACTTC CTGAAGGTGA TCGGCAAGGG GAGCTTCGGC 300

AAAGTCCTGC TGGCACGCCA CCGCGCCGAC GACCAGTTTT ACGCAGTCAA AGTCCTGCAG 360

AAGAAGGCGA TTCTCAAGAA GAAGGAGGAA AAACACATCA TGTCAGAGAG GAATGTGCTG 420

CTGAAGAATG TCAAGCACCC GTTCCTGGTT GGCCTGCACT ACTCCTTCCA AACGGCGGAC 480

AAACTCTACT TCATCCTGGA CTACATCAAC GGAGGAGAGT TGTTCTACCA CCTGCAGAGA 540

GAGCGCTGCT TCCTCGAGCC CCGAGCCAGG TTCTACTCGG CGGAGATCGC CAGCGCACTG 600

GGCTACCTCC ACTCCCTCAA CATCGTCTAC AGGGACCTGA AGCCGGAGAA CATCCTGCTG 660

GACTCCCAGG GGCACATCAT TCTCACCGAT TTTGGCCTCT GCAAGGAGAA CATCGAACCC 720

AACGGCACCA CGTCGACCTT CTGCGGTACT CCAGAGTATT TGGCTCCCGA GGTTCTACAC 780

AAGCAGCCGT ACGACCGGAC GGTGGACTGG TGGTGTTTAG GGGCTGTCCT CTACGAGATG 840

CTCTACGGCC TGCCTCCGTT CTACAGCCGC AACACAGCAG AGATGTACGA CAACATCCTG 900

AACAAGCCGC TGCAGCTGAA ACCCAACATT TCCAACGCGG CCAGGCACCT GCTGGAAGGC 960

CTCCTGCAGA AGGACCGAAC CAAGAGGCTG GGCTGCGCGG ATGACTTTAT TGAAATTAAG 1020

AGCCACGTAT TCTTCTCCCC CATCAACTGG GACGACCTCA ACGCAAAGAA GATCACCCCT 1080

CCCTTCAACC CCAACGTGAC GGGACCTAAC GACCTCCGGC ACTTTGATCC AGAGTTCACA 1140

GACGAGCCGG TGCCCAGCTC CATCGGCTGT TCCCCAGACA GCGCGCTCGT TACAGCCAGC 1200

ATCAAAGACG CCGCCGAGGC CTTTGTGGGC TTCTCGTACG CCCCGTCTAT GGATTCCTAC 1260

CTATAG 1266

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f+flkvigkgsfgkvlla+++ad++fyavkvlqkkailkkkeekhim+ernvllknvkhp

Q: 88    FHFLKVIGKGSFGKVLLARHRADDQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP  147

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqta+klyf+ldy+nggelf+hlqrer+fleprarfy+aeiasalgylhsln

Q: 148   FLVGLHYSFQTADKLYFILDYINGGELFYHLQRERCFLEPRARFYSAEIASALGYLHSLN  207

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh++ltdfglcke+ie + ttstfcgtpeylapevl+k+pydrt

Q: 208   IVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRT  267

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysr++aemydnilnkplqlkp+is+aa++lle+ll+kdr+

Q: 268   VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRT  327

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlg  +df+eik+hvff

Q: 328   KRLGCADDFIEIKSHVFF  345

         *****************9

Domain Sequence
(FASTA)

FHFLKVIGKG SFGKVLLARH RADDQFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP 60

FLVGLHYSFQ TADKLYFILD YINGGELFYH LQRERCFLEP RARFYSAEIA SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHII LTDFGLCKEN IEPNGTTSTF CGTPEYLAPE VLHKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNISNAARHL LEGLLQKDRT 240

KRLGCADDFI EIKSHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013