EKS-GAA-00264

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00264

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	467.4	3.6E-140	151	493	343

Status

Unreviewed

Ensembl Protein

ENSGACP00000014990

UniProt Accession

G3PBL6;

Protein Name

Protein Synonyms/Alias

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000011338	ENSGACP00000014990	ENSGACT00000015018

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

564

Protein Sequence
(FASTA)

FPLPSGLIMS VKHAISRGLE LGRSALQLGL LKSGGRFAAK LRADRLRVAP SSRAVQPQAF 60

LPSRYRYYRT SLKGLAARLQ SAGFGRRLGG GSPRNRAAFW AFGLGVGLIE QQLDDDRRSA 120

ATCDEIQAVF RKKKIQSSFK PCTSGYKLQD YIIGNQIGKG SNAAVYEAAA QLAPQKCSPP 180

QLGEEEGETA PTLRTFPMAI KMMWNIGAGS SSEAIFKAMS QELVPAGPLA LKREEEEITL 240

DGYFGVLPKR VSAHPNVIRV SRAFTADVPL LPGAQEEYPD VLPARLNPAG LGNNRTLFLV 300

MKNYPCTLRQ YLKVSTPGHR QGSLMVLQLL EGVDHLCRQG VAHRDLKSDN VLLEFDSDGC 360

PRLVITDFGC CLAQGDSDLR LPFNSTYVDK GGNASLMAPE VATAVPGRGV VIDYSKADAW 420

AVGAISYEIF GQPNPFYRAV GLQSESFQEK QLPPLPSGVP ADVQLVIRFL LRRNPSKRPS 480

ARVAANMLHL SLWGRKALVN QDSVGMRKLA DWLLCQSAVV LLKGCGGPSG NKVEAELQRS 540

FLSNLDLEDL RTAAGFLLYG RAQR 564

Nucleotide Sequence
(FASTA)

TTCCCTTTAC CGTCCGGGTT GATCATGTCT GTGAAACACG CCATCAGCCG GGGGCTGGAG 60

TTGGGCCGGT CCGCCCTTCA GCTCGGTCTC CTCAAGTCAG GAGGCCGGTT CGCAGCGAAG 120

CTCCGAGCGG ACCGTCTCCG CGTCGCGCCG TCGAGCCGCG CCGTCCAGCC TCAGGCTTTC 180

CTGCCGTCTC GGTACCGCTA CTACCGCACC TCGTTGAAGG GCCTGGCAGC CCGGCTTCAG 240

TCCGCCGGGT TCGGGCGAAG GCTCGGCGGC GGGTCCCCCC GGAACAGGGC CGCGTTCTGG 300

GCTTTCGGTC TCGGTGTGGG GCTCATCGAG CAGCAGCTTG ACGACGATAG AAGGAGCGCG 360

GCGACGTGTG ACGAGATCCA GGCGGTGTTC AGGAAGAAAA AAATCCAGAG TTCATTCAAG 420

CCATGCACCT CTGGATATAA ACTGCAGGAT TACATCATTG GGAACCAGAT TGGGAAAGGC 480

TCCAACGCTG CTGTGTACGA GGCTGCAGCT CAGTTGGCGC CTCAGAAGTG CTCCCCGCCT 540

CAGCTGGGAG AAGAGGAAGG GGAGACCGCT CCAACGCTCA GAACCTTCCC TATGGCTATC 600

AAGATGATGT GGAACATTGG GGCAGGGTCG TCCAGTGAGG CGATTTTTAA AGCCATGTCC 660

CAGGAGCTGG TGCCCGCAGG CCCTCTGGCC CTAAAGCGGG AGGAAGAAGA AATCACTCTG 720

GATGGATATT TTGGAGTCCT GCCCAAAAGA GTGTCAGCGC ACCCTAATGT GATCAGAGTG 780

TCCCGGGCCT TCACGGCGGA CGTCCCATTG CTACCAGGTG CACAGGAGGA GTATCCAGAT 840

GTGCTGCCAG CCAGGCTGAA CCCTGCTGGT TTGGGCAACA ATCGCACTCT TTTCCTCGTC 900

ATGAAGAATT ACCCCTGCAC ACTGCGCCAG TACCTGAAAG TGTCCACGCC AGGCCACAGG 960

CAGGGCTCTC TGATGGTGCT GCAGCTCCTT GAGGGGGTGG ACCACCTGTG TAGACAGGGT 1020

GTTGCTCACA GGGATCTCAA ATCAGACAAC GTGCTGTTGG AGTTTGACTC AGATGGATGC 1080

CCTCGTTTAG TAATTACCGA CTTTGGCTGC TGCCTGGCTC AGGGTGACTC TGATCTACGG 1140

CTGCCATTCA ACAGCACATA TGTCGACAAA GGAGGGAACG CCTCCCTAAT GGCCCCTGAG 1200

GTGGCCACCG CAGTTCCAGG GCGCGGCGTG GTGATCGACT ACAGCAAGGC GGATGCCTGG 1260

GCAGTGGGCG CCATCTCCTA TGAGATATTC GGGCAGCCTA ACCCGTTCTA TCGAGCGGTG 1320

GGACTGCAGA GCGAGAGCTT CCAGGAGAAG CAGCTTCCTC CGCTGCCCTC CGGTGTTCCA 1380

GCTGATGTGC AGCTAGTGAT CCGATTCCTC CTCAGGAGAA ACCCAAGCAA GCGCCCCAGT 1440

GCCCGCGTGG CCGCTAACAT GCTACATCTT AGCCTGTGGG GACGGAAGGC CCTGGTCAAC 1500

CAAGACAGCG TTGGCATGAG GAAGCTTGCT GATTGGCTGC TGTGCCAGTC TGCTGTGGTT 1560

CTCCTGAAGG GCTGCGGTGG ACCCAGTGGC AACAAGGTGG AGGCGGAGCT TCAGAGGAGC 1620

TTCCTGTCCA ACCTGGACCT GGAGGACCTT CGCACTGCTG CGGGCTTCCT CCTCTATGGG 1680

CGAGCGCAGC GT 1692

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgllgkevtvvlaeidqesavaakkfpl  60

         y ig+ +gkg naavyea    ++q+ +               l e+++e a++ ++fp+

Q: 151   YIIGNQIGKGSNAAVYEAAAQLAPQKCSPP------------QLGEEEGETAPTLRTFPM  198

         89****************999999987653............46789999**********

S: 61    aiklmfnieadssseallksmsqelvpasrva.........ldgeygavpkllakhPniv  111

         aik+m+ni a+sssea++k+msqelvpa   a         ldg +g +pk+++ hPn++

Q: 199   AIKMMWNIGAGSSSEAIFKAMSQELVPAGPLAlkreeeeitLDGYFGVLPKRVSAHPNVI  258

         ***************************9877755566666688999999***********

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

         rv raf+ +v+llP+a ++yPd+lparl+p glg+++tl+lvmk+y++tlr+yl++ ++

Q: 259   RVSRAFTADVPLLPGAQEEYPDVLPARLNPAGLGNNRTLFLVMKNYPCTLRQYLKVSTPG  318

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

         +r++ l+++qlle+vdhl ++gvahrdlksdn+l+e+d+d++P lvi+dfGCcla+   +

Q: 319   HRQGSLMVLQLLEGVDHLCRQGVAHRDLKSDNVLLEFDSDGCPRLVITDFGCCLAQGDSD  378

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         lrlp++s++vdkGGna+lmaPe++tavpG+ +vi+y+kad+WavGa++yeifg+ nPfy

Q: 379   LRLPFNSTYVDKGGNASLMAPEVATAVPGRGVVIDYSKADAWAVGAISYEIFGQPNPFY-  437

         ***********************************************************.

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

           +  l+s+s+qe+qlP+lp+ vp +++ +++ ll+r++skr+sa++aan+l+lsl+

Q: 438   -RAVGLQSESFQEKQLPPLPSGVPADVQLVIRFLLRRNPSKRPSARVAANMLHLSLW  493

         .8899***************************************************9

Domain Sequence
(FASTA)

YIIGNQIGKG SNAAVYEAAA QLAPQKCSPP QLGEEEGETA PTLRTFPMAI KMMWNIGAGS 60

SSEAIFKAMS QELVPAGPLA LKREEEEITL DGYFGVLPKR VSAHPNVIRV SRAFTADVPL 120

LPGAQEEYPD VLPARLNPAG LGNNRTLFLV MKNYPCTLRQ YLKVSTPGHR QGSLMVLQLL 180

EGVDHLCRQG VAHRDLKSDN VLLEFDSDGC PRLVITDFGC CLAQGDSDLR LPFNSTYVDK 240

GGNASLMAPE VATAVPGRGV VIDYSKADAW AVGAISYEIF GQPNPFYRAV GLQSESFQEK 300

QLPPLPSGVP ADVQLVIRFL LRRNPSKRPS ARVAANMLHL SLW 343

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>