EKS-GAA-00341

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00341

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	433.6	4.4E-130	230	517	288

Status

Unreviewed

Ensembl Protein

ENSGACP00000015273

UniProt Accession

G3PCE9;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000011543	ENSGACP00000015273	ENSGACT00000015302

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

528

Protein Sequence
(FASTA)

IESMKVCRRS FTLYLGFSLQ AAGQNPDHVL QGTGVKPEAR RPGEDSTISP EDAARFLSCY 60

CSGHCPEDAT NNTCQTNGQC FAIIEEDEHG EAVLTSGCMK YEGSHFQCKD SPNAQTRRTI 120

ECCNTDLCNR DLQPTLPPQP PPGNIPDGSP HWLAFLISMT VCCCALICVT VVCYYRYKWQ 180

SERQRYHKDL EQEIFIPSGE SLKDLIHQSQ SSGSGSGLPL LVQRTIAKQI QMVRQIGKGR 240

YGEVWLGRWR GEKVAVKVFF TREEGSWFRE TEIYQTVLMR HENILGFIAA DIKGTGAFTQ 300

LFLITDYHEN GSLCDFLKLT TLDTPTLLRL AYSAACGLCH LHTEIYGTQG KPAIAHRDLK 360

SKNILIKKNG ACCIADLGLA VKFNSDTNEV DVPLSTRVGT RRYMAPEVLD ESLNKNHFQA 420

YIMADMYSYG LVIWEMARRC VSGGIVEDYQ LPYYEMVPSD PSYEDMLEVV CVKGLRPTVS 480

NRWNSDECLR AMLKLMSECW AHNPASRLTT LRVKKTLAKM VESQDIKI 528

Nucleotide Sequence
(FASTA)

ATCGAATCAA TGAAAGTCTG CAGGAGGAGC TTCACATTGT ATTTAGGTTT CTCTCTCCAA 60

GCTGCGGGTC AGAACCCGGA CCACGTCCTG CAGGGCACCG GGGTCAAACC TGAGGCCCGG 120

CGGCCCGGCG AGGACTCCAC CATCTCCCCC GAGGACGCCG CGCGCTTCCT CAGCTGCTAC 180

TGCTCCGGTC ACTGTCCCGA AGACGCCACC AACAACACCT GCCAGACCAA CGGCCAGTGT 240

TTCGCCATCA TCGAGGAGGA TGAGCACGGT GAGGCCGTCC TCACCTCTGG CTGCATGAAG 300

TATGAAGGAT CACACTTCCA GTGCAAGGAC TCTCCCAACG CTCAGACCAG GAGGACCATC 360

GAGTGCTGCA ACACCGACCT CTGCAACAGG GACCTGCAGC CCACCCTCCC CCCTCAGCCT 420

CCGCCCGGTA ACATTCCTGA CGGCAGCCCT CACTGGCTGG CCTTCCTCAT CTCCATGACG 480

GTCTGCTGCT GCGCCCTGAT CTGCGTCACC GTGGTCTGTT ACTACAGGTA CAAGTGGCAG 540

AGTGAGCGGC AGCGATACCA CAAGGATCTG GAGCAGGAGA TCTTCATCCC CAGTGGAGAG 600

TCCCTCAAAG ACCTCATCCA CCAATCACAG AGCTCCGGCA GCGGCTCCGG GCTCCCCCTG 660

CTGGTGCAAC GGACCATCGC CAAGCAGATC CAGATGGTGC GTCAGATCGG TAAGGGGCGG 720

TACGGCGAGG TGTGGCTCGG CCGCTGGAGG GGAGAGAAGG TGGCCGTCAA GGTCTTCTTC 780

ACCCGGGAGG AAGGCAGCTG GTTCCGAGAG ACGGAGATCT ACCAGACGGT CCTGATGAGA 840

CACGAGAACA TCCTCGGCTT CATCGCGGCC GACATTAAAG GCACCGGCGC CTTCACGCAG 900

CTCTTCCTCA TCACCGACTA CCACGAGAAC GGCTCGCTGT GCGACTTCCT GAAGCTGACC 960

ACGCTGGACA CGCCGACCCT GCTGCGGCTG GCGTACTCCG CCGCCTGCGG CCTCTGCCAC 1020

CTGCACACGG AGATCTACGG CACGCAGGGG AAGCCGGCCA TCGCCCACCG CGACCTGAAG 1080

AGCAAGAACA TCCTGATCAA GAAGAACGGC GCCTGCTGCA TCGCCGACCT CGGCCTCGCC 1140

GTCAAGTTCA ACAGCGACAC TAACGAGGTG GACGTCCCCC TGAGCACCCG GGTCGGGACG 1200

AGGCGCTACA TGGCTCCCGA GGTCCTGGAC GAGAGCCTCA ACAAGAACCA CTTCCAGGCT 1260

TACATCATGG CCGACATGTA CAGCTACGGC CTCGTCATCT GGGAGATGGC CCGACGCTGC 1320

GTCTCCGGAG GCATCGTGGA GGACTACCAG CTGCCCTACT ACGAGATGGT TCCCTCCGAC 1380

CCGTCCTATG AGGACATGCT GGAGGTGGTT TGTGTTAAAG GACTGAGGCC GACGGTGTCC 1440

AACCGCTGGA ACAGTGACGA GTGCCTTCGA GCCATGCTGA AGCTGATGTC CGAGTGCTGG 1500

GCTCATAACC CCGCCTCTCG CCTCACCACC CTCAGAGTGA AGAAGACGCT TGCCAAGATG 1560

GTGGAGTCCC AGGACATCAA GATTTGA 1587

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw +++rge+vAvK+f+t++e sw+rE+eiyqtvl+rhenil+fia

Q: 230   IQMVRQIGKGRYGEVWLGRWRGEKVAVKVFFTREEGSWFRETEIYQTVLMRHENILGFIA  289

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++  t+l+l+t+yhe+gsL+d+Lk +tld+ +llrla+s+a+Gl+hLH+ei gt+

Q: 290   ADIKGTGAFTQLFLITDYHENGSLCDFLKLTTLDTPTLLRLAYSAACGLCHLHTEIYGTQ  349

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNil+kk+++cciaDlGLa+k++++++e+d+  +++vGt+RYmaPE

Q: 350   G--KPAIAHRDLKSKNILIKKNGACCIADLGLAVKFNSDTNEVDVPLSTRVGTRRYMAPE  407

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+a+ +aD+Ys gLv+WE+a+Rc + +++ve+y+lp++e+v+sdPs+e+m

Q: 408   VLDESLNKNHFQAYIMADMYSYGLVIWEMARRCVS-GGIVEDYQLPYYEMVPSDPSYEDM  466

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

          evv++k lrP+++++w+++e+l+++ kl++ecW+++p++Rlt+lrvkk+l

Q: 467   LEVVCVKGLRPTVSNRWNSDECLRAMLKLMSECWAHNPASRLTTLRVKKTL  517

         *************************************************97

Domain Sequence
(FASTA)

IQMVRQIGKG RYGEVWLGRW RGEKVAVKVF FTREEGSWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGAFT QLFLITDYHE NGSLCDFLKL TTLDTPTLLR LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GACCIADLGL AVKFNSDTNE VDVPLSTRVG TRRYMAPEVL 180

DESLNKNHFQ AYIMADMYSY GLVIWEMARR CVSGGIVEDY QLPYYEMVPS DPSYEDMLEV 240

VCVKGLRPTV SNRWNSDECL RAMLKLMSEC WAHNPASRLT TLRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013