EKS-GAA-00254

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00254

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	519.1	3.0E-156	5	288	284

Status

Unreviewed

Ensembl Protein

ENSGACP00000015665

UniProt Accession

G3PDJ1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000011842	ENSGACP00000015665	ENSGACT00000015696

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

358

Protein Sequence
(FASTA)

RMEKYEKIAK IGEGSYGVVF KCRNKDTGQV VAIKKFVESE DDPIIKKIAL REIRMLKQLK 60

HGNLVNLIEV FRRKRKLHLV FEYCDHTVLN ELDRHPRGVP EHLVRSITWQ TLQAVNFCHK 120

QNCIHRDVKP ENILITKHRV IKLCDFGFAR ILTGPCDYYT DYVATRWYRA PELLVGDTRY 180

GPPVDVWAIG CVFAELLSGT PLWPGKSDMD QLYLIRKTLG DLTPRHQQVF SNNQFFCGVS 240

IPEPQDMEPL EKKYPNLSHQ ARSLMKGCLR MDPSERLTCE QLLQQPYFDS LREKSSGASR 300

EHDRSGHRRT RLPRKHLPPG LSFMQYLPQL TSSSIFPVLD NKKYYNNLRK FNYHLPNI 358

Nucleotide Sequence
(FASTA)

AGGATGGAGA AGTATGAGAA GATTGCAAAA ATCGGGGAGG GCTCCTACGG CGTCGTCTTC 60

AAGTGCAGAA ACAAAGACAC CGGGCAGGTC GTCGCCATCA AGAAGTTTGT GGAGTCAGAG 120

GACGATCCCA TTATAAAAAA GATTGCACTG AGGGAGATCA GAATGCTTAA GCAACTGAAA 180

CACGGCAACC TGGTGAATCT GATCGAGGTG TTTCGGCGGA AGCGGAAGCT CCACCTCGTG 240

TTCGAGTACT GCGACCACAC GGTGCTCAAC GAGCTGGACC GACACCCCAG AGGGGTCCCA 300

GAGCACCTTG TTAGAAGTAT AACCTGGCAG ACACTTCAAG CTGTCAACTT CTGTCACAAG 360

CAGAATTGCA TCCACAGAGA CGTCAAGCCG GAAAACATTC TCATCACCAA ACACCGAGTC 420

ATCAAGCTCT GTGACTTTGG GTTCGCACGG ATTCTCACCG GCCCATGTGA CTACTACACG 480

GACTACGTGG CGACCCGTTG GTACCGGGCC CCCGAGCTGC TGGTGGGGGA CACTCGGTAC 540

GGCCCCCCGG TGGACGTGTG GGCGATCGGT TGTGTGTTCG CTGAGCTGCT GTCGGGGACG 600

CCGCTGTGGC CCGGGAAGTC TGACATGGAT CAGCTGTATC TGATCAGAAA GACTCTCGGA 660

GATCTGACAC CTCGACACCA GCAGGTCTTC AGCAACAACC AGTTCTTCTG TGGAGTTTCC 720

ATCCCAGAGC CACAAGACAT GGAGCCTTTG GAGAAAAAAT ATCCAAATCT CTCGCATCAA 780

GCTCGGAGTC TCATGAAGGG CTGCCTGAGG ATGGACCCGT CGGAGCGGCT GACCTGTGAG 840

CAGCTCCTCC AGCAGCCGTA CTTCGACAGC CTGCGAGAAA AGAGCTCCGG CGCCTCCCGG 900

GAGCACGACC GCTCCGGCCA CCGGAGGACG CGGTTACCTC GCAAACACCT CCCTCCTGGG 960

TTATCCTTCA TGCAGTATTT GCCGCAGCTC ACCAGCAGCA GTATCTTCCC AGTTTTGGAC 1020

AATAAGAAGT ACTACAACAA CCTGCGCAAA TTCAACTATC ATCTACCGAA CATCTAG 1077

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek++k+GeGsyGvv+kcrnkdtgq+vaikkf+esedd+ +kkialrei++lkqlkh nl

Q: 5     YEKIAKIGEGSYGVVFKCRNKDTGQVVAIKKFVESEDDPIIKKIALREIRMLKQLKHGNL  64

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk+kl+lvfey+d+tvl+el+r+p+Gv+e+lv++i++q+l+a++fchk+n+i

Q: 65    VNLIEVFRRKRKLHLVFEYCDHTVLNELDRHPRGVPEHLVRSITWQTLQAVNFCHKQNCI  124

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k+ v+klcdfGfar+l++p d+ytdyvatrwyrapellvgdt+yG++v

Q: 125   HRDVKPENILITKHRVIKLCDFGFARILTGPCDYYTDYVATRWYRAPELLVGDTRYGPPV  184

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G+pl+pgksd+dqly+irktlG+l+prhq++fs+n++f Gv++pe+

Q: 185   DVWAIGCVFAELLSGTPLWPGKSDMDQLYLIRKTLGDLTPRHQQVFSNNQFFCGVSIPEP  244

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +d+e+lekkyp+l++ + +l+k+cl++dp+erl+ce+ll+++yf

Q: 245   QDMEPLEKKYPNLSHQARSLMKGCLRMDPSERLTCEQLLQQPYF  288

         ******************************************99

Domain Sequence
(FASTA)

YEKIAKIGEG SYGVVFKCRN KDTGQVVAIK KFVESEDDPI IKKIALREIR MLKQLKHGNL 60

VNLIEVFRRK RKLHLVFEYC DHTVLNELDR HPRGVPEHLV RSITWQTLQA VNFCHKQNCI 120

HRDVKPENIL ITKHRVIKLC DFGFARILTG PCDYYTDYVA TRWYRAPELL VGDTRYGPPV 180

DVWAIGCVFA ELLSGTPLWP GKSDMDQLYL IRKTLGDLTP RHQQVFSNNQ FFCGVSIPEP 240

QDMEPLEKKY PNLSHQARSL MKGCLRMDPS ERLTCEQLLQ QPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013