EKS-GAA-00056

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00056

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	371.2	3.4E-111	37	303	267

Status

Unreviewed

Ensembl Protein

ENSGACP00000017332

UniProt Accession

G3PIB7;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK1

Gene Synonyms/Alias

VRK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000013081	ENSGACP00000017344	ENSGACT00000017378
ENSGACG00000013081	ENSGACP00000017332	ENSGACT00000017366

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

351

Protein Sequence
(FASTA)

MPPKAKAAGR GRAPAKRKLA EEFPPGEVLT DTGKKTWKLG APIGQGGFGL IYLADEDCGK 60

PVGAEAPYVI KVEPSDNGPL FSELKFYMRA AKPDLIQSWM KSRKLKALGV PRYWGSGLHE 120

RGGKRYRFMV IDRLGTDLQK KFEECGRRFP RKLVLQLGLR LLGILEYIHD HEYVHADIKA 180

SNLMLSHSDP NQVYLVDYGL AYRYAPDSVI KEYKEDPKRC HDGTIEFTSI DAHKGATACR 240

RSDLEILVYC MIQWLCGRLP WEDKLQDPLY VRDAKIRSQE NISEFLTKCF SSQDKPAEIQ 300

RFMEEVTSLG YRDRPAYDKL RSILQAGLEA IQAKDDGKLQ FSPPVGGGVA A 351

Nucleotide Sequence
(FASTA)

ATGCCCCCTA AAGCCAAAGC GGCAGGCAGA GGCAGAGCTC CGGCCAAGCG GAAGCTGGCG 60

GAGGAGTTTC CCCCCGGCGA GGTCCTCACG GACACCGGGA AGAAGACCTG GAAGCTGGGC 120

GCTCCGATCG GCCAGGGCGG CTTCGGCCTC ATCTATCTGG CGGATGAGGA TTGTGGCAAA 180

CCCGTCGGTG CTGAGGCTCC TTATGTCATC AAAGTGGAGC CCAGTGACAA CGGGCCGCTG 240

TTCTCTGAGC TCAAGTTCTA CATGCGCGCC GCCAAGCCCG ACCTGATTCA GAGCTGGATG 300

AAGTCCCGCA AGTTGAAAGC GCTGGGCGTG CCCAGGTACT GGGGCTCGGG CCTGCATGAG 360

CGCGGGGGCA AAAGGTACAG GTTCATGGTC ATCGACCGGC TCGGCACCGA CCTGCAGAAG 420

AAGTTTGAAG AATGTGGAAG GAGGTTCCCG AGGAAACTGG TCCTGCAGCT CGGCCTTCGA 480

CTGCTGGGTA TTCTGGAGTA CATCCACGAC CACGAGTACG TGCACGCTGA CATCAAGGCA 540

TCCAACCTCA TGTTGAGCCA CAGCGATCCC AACCAGGTTT ACCTGGTGGA TTATGGGCTG 600

GCCTACAGGT ACGCACCTGA CAGTGTCATC AAGGAGTACA AAGAGGACCC CAAAAGATGC 660

CACGATGGCA CCATCGAGTT CACCAGCATC GATGCACACA AAGGAGCAAC TGCGTGTAGG 720

CGCAGTGACC TGGAGATCCT GGTCTACTGT ATGATCCAGT GGCTGTGTGG ACGGCTGCCC 780

TGGGAGGACA AGCTGCAGGA CCCCCTCTAC GTCAGAGACG CCAAAATCAG GAGCCAAGAG 840

AACATCTCCG AATTTCTGAC CAAGTGTTTC TCCTCTCAAG ACAAGCCAGC TGAGATCCAG 900

AGGTTCATGG AGGAGGTGAC CTCTCTGGGT TACCGAGACC GGCCGGCGTA CGACAAGCTG 960

CGCTCCATCC TGCAGGCCGG CCTGGAGGCC ATCCAGGCTA AAGACGACGG CAAGCTGCAG 1020

TTCAGTCCTC CGGTCGGTGG AGGGGTCGCC GCC 1053

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wklg +ig+ggfG iyla     k ++ +a +v+kvep++nGpLf+elkfy+raak++ i

Q: 37    WKLGAPIGQGGFGLIYLAdeDCGKPVGAEAPYVIKVEPSDNGPLFSELKFYMRAAKPDLI  96

         9*****************9555577899********************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         ++w+k +klk lg+P +++sGlhe +g++yRf+v++rlg+dLqk  e+ g+r+ +k vlq

Q: 97    QSWMKSRKLKALGVPRYWGSGLHERGGKRYRFMVIDRLGTDLQKKFEECGRRFPRKLVLQ  156

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++rll +ley+H++eYvH+dikA+nl+l++ +++qvyLvdyGlayry+p+++ keyked

Q: 157   LGLRLLGILEYIHDHEYVHADIKASNLMLSHSDPNQVYLVDYGLAYRYAPDSVIKEYKED  216

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         ++r+HdGt+efts+DaHkG++  rRsDleiL Yc+++Wl+g LPWe++l+dp +v++ak

Q: 217   PKRCHDGTIEFTSIDAHKGATACRRSDLEILVYCMIQWLCGRLPWEDKLQDPLYVRDAKI  276

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         +  ++++e+l+k++ ++ +++e+++++

Q: 277   RSQENISEFLTKCFSSQDKPAEIQRFM  303

         ************************997

Domain Sequence
(FASTA)

WKLGAPIGQG GFGLIYLADE DCGKPVGAEA PYVIKVEPSD NGPLFSELKF YMRAAKPDLI 60

QSWMKSRKLK ALGVPRYWGS GLHERGGKRY RFMVIDRLGT DLQKKFEECG RRFPRKLVLQ 120

LGLRLLGILE YIHDHEYVHA DIKASNLMLS HSDPNQVYLV DYGLAYRYAP DSVIKEYKED 180

PKRCHDGTIE FTSIDAHKGA TACRRSDLEI LVYCMIQWLC GRLPWEDKLQ DPLYVRDAKI 240

RSQENISEFL TKCFSSQDKP AEIQRFM 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>