EKS-GAA-00589

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00589

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	363.8	6.6E-109	26	280	255

Status

Unreviewed

Ensembl Protein

ENSGACP00000017983

UniProt Accession

G3PK53;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK4

Gene Synonyms/Alias

CAMK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000013599	ENSGACP00000017988	ENSGACT00000018023
ENSGACG00000013599	ENSGACP00000017983	ENSGACT00000018018

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

360

Protein Sequence
(FASTA)

TSRPGSAPVE FWVDGSRRDG AVEEFYTLSS ELGRGATSIV YRCEEKQTQK PYALKVLKKT 60

IDKKIVRTEI GVLLRLSHPN IIQLKEIFET DTDIALVLEL VTGGELFDRI VERGYYSERD 120

AAHVIKQILE AVAYLYENGV VHRDLKPENL LYADLSLDAP LKIADFGLSK IIDDQVTMKT 180

VCGTPGYCAP EILRGNAYGP EVDMWSVGVI LYILLCGFEP FFDPRGDQYM YSRILNCDYE 240

FVSPWWDDVS LNAKDLVSKL IVLDPPKRLS VREALQHPWV LGKAARFSHM DTAQRKLQEF 300

NARRKLKAAM KAVVATSRMH ESSRRRTDSC EIPGSGTSRQ SSMQQDPPPE STSPAPEDKE 360

Nucleotide Sequence
(FASTA)

ACGTCCCGGC CTGGTTCGGC GCCGGTGGAG TTCTGGGTGG ACGGGTCGAG GCGGGACGGG 60

GCGGTGGAGG AGTTCTACAC CCTGAGCTCT GAGCTGGGCA GAGGAGCAAC GTCCATCGTG 120

TATCGCTGTG AGGAGAAGCA GACTCAGAAG CCCTACGCTC TCAAAGTCCT CAAGAAAACG 180

ATTGACAAGA AAATAGTTCG CACGGAAATC GGCGTGCTGT TGCGTCTTTC CCACCCAAAC 240

ATTATCCAGC TGAAGGAGAT CTTCGAGACG GACACGGACA TCGCTCTGGT GCTGGAGCTG 300

GTCACAGGAG GAGAGCTGTT TGACAGGATC GTGGAGCGAG GTTACTACAG CGAGAGAGAC 360

GCCGCTCACG TCATCAAACA GATCCTGGAG GCTGTGGCGT ATCTTTACGA GAACGGAGTC 420

GTGCATCGAG ACCTCAAACC AGAGAACCTC CTGTACGCCG ACTTGTCTCT GGACGCTCCG 480

CTGAAGATCG CCGACTTTGG TCTTTCCAAA ATCATTGATG ACCAGGTGAC CATGAAGACC 540

GTCTGTGGCA CGCCGGGGTA CTGTGCTCCA GAGATCCTGC GGGGAAATGC TTACGGCCCT 600

GAGGTGGACA TGTGGTCGGT GGGCGTCATC CTCTACATCC TACTCTGTGG GTTCGAGCCC 660

TTCTTCGACC CGAGGGGGGA TCAGTACATG TACAGTCGAA TCCTCAACTG CGACTACGAG 720

TTTGTGTCTC CGTGGTGGGA CGACGTCTCC CTCAATGCCA AGGATCTGGT CAGTAAGCTC 780

ATCGTCCTTG ACCCCCCCAA GCGCCTCAGC GTCCGGGAGG CCTTGCAGCA CCCCTGGGTG 840

CTGGGCAAAG CGGCCCGCTT CTCTCACATG GACACGGCCC AGAGGAAGCT GCAGGAGTTC 900

AACGCTCGCC GCAAACTGAA GGCCGCCATG AAGGCCGTCG TCGCTACCAG TCGGATGCAC 960

GAGAGTTCGC GGCGTCGCAC CGACAGCTGT GAGATTCCAG GCTCGGGGAC TTCAAGGCAG 1020

AGTAGCATGC AGCAGGACCC GCCTCCTGAG TCAACAAGCC CCGCCCCTGA GGATAAAGAA 1080

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         y+l+++lG+Ga+s v++++ek+tqk++a+kv+kk+    +++ v++ei vl +l+hpni+

Q: 26    YTLSSELGRGATSIVYRCEEKQTQKPYALKVLKKTI---DKKIVRTEIGVLLRLSHPNII  82

         8899****************************9998...89*******************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +lk+i+e+++ + lvlelvtGGelfdrive+g+y+e+da++vikq+leav+yl+e+g+vh

Q: 83    QLKEIFETDTDIALVLELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLYENGVVH  142

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly++ + d+++kiadfGlsk+ +++  +kt+cGt+gy+ape+l+ ++y+ +v

Q: 143   RDLKPENLLYADLSLDAPLKIADFGLSKIIDDQvTMKTVCGTPGYCAPEILRGNAYGPEV  202

         ****************************88888689************************

S: 180   dvWsiGvityillcGyppfydekeekl.lekilkgeyefesPyWdeisesakdfikklle  238

         d+Ws+Gvi+yillcG++pf+d + +++  ++il+++yef sP+Wd++s +akd++ kl+

Q: 203   DMWSVGVILYILLCGFEPFFDPRGDQYmYSRILNCDYEFVSPWWDDVSLNAKDLVSKLIV  262

         *********************998886379******************************

S: 239   ldpekrytieqaledpWi  256

         ldp kr+ +++al++pW+

Q: 263   LDPPKRLSVREALQHPWV  280

         *****************7

Domain Sequence
(FASTA)

YTLSSELGRG ATSIVYRCEE KQTQKPYALK VLKKTIDKKI VRTEIGVLLR LSHPNIIQLK 60

EIFETDTDIA LVLELVTGGE LFDRIVERGY YSERDAAHVI KQILEAVAYL YENGVVHRDL 120

KPENLLYADL SLDAPLKIAD FGLSKIIDDQ VTMKTVCGTP GYCAPEILRG NAYGPEVDMW 180

SVGVILYILL CGFEPFFDPR GDQYMYSRIL NCDYEFVSPW WDDVSLNAKD LVSKLIVLDP 240

PKRLSVREAL QHPWV 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013