EKS-GAA-00082

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00082

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	364.1	6.2E-109	95	379	285

Status

Unreviewed

Ensembl Protein

ENSGACP00000018750

UniProt Accession

G3PMB9;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK14

Gene Synonyms/Alias

CDK14;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000014194	ENSGACP00000018750	ENSGACT00000018788

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

429

Protein Sequence
(FASTA)

QICVTKMSTR SGQGSDSVIK PLDTIPEDKK VRVQRTQSGF DSFEKPASQV KRVHSENNAC 60

INAKGSPASK ESPKLRRHSS PSSPTSPKFG KADSYEKLEK LGEGSYATVY KGKSKVNGKL 120

VALKVIRLQE EEGTPFTAIR EASLLKGLKH SNIVLLHDII HTKETLTLVF EYVHTDLCQY 180

MDKHPGGLHP DNVKLFLFQL LRGLSYIHQR YILHRDLKPQ NLLISDTGEL KLADFGLARA 240

KSVPSHTYSN EVVTLWYRPP DVLLGSTDYS TCLDMWGVGC IFIEMIQGVA AFPGMKDIQD 300

QLERIFLVIG TPSEDSWPGV TSLPHFKPDR FTVYSAKKLR QAWNKLGYVD HAEELASRFL 360

QCFPKNRLSA QAALNHEYFS NLPPRLWELQ DMSSIFTGPN VKLQTESGDS IQVCARQNSH 420

GKASSGSKH 429

Nucleotide Sequence
(FASTA)

CAGATATGTG TCACAAAGAT GTCAACACGC AGCGGCCAGG GATCGGACTC GGTCATCAAG 60

CCCCTGGACA CCATCCCTGA GGACAAGAAG GTCAGGGTGC AGCGCACGCA GAGTGGCTTT 120

GACTCGTTTG AGAAGCCCGC TAGCCAGGTG AAGAGGGTCC ACTCCGAGAA CAATGCCTGC 180

ATTAACGCCA AGGGCTCGCC CGCCAGCAAG GAGTCGCCCA AACTGCGCCG CCACTCCAGC 240

CCTAGTTCTC CCACAAGTCC CAAGTTTGGA AAGGCTGATT CCTATGAGAA GCTGGAGAAA 300

CTGGGAGAGG GTTCATATGC TACAGTTTAC AAAGGAAAGA GCAAGGTGAA TGGGAAACTG 360

GTCGCTCTGA AGGTGATTCG TCTGCAAGAG GAGGAAGGGA CGCCATTCAC GGCCATACGA 420

GAAGCATCTC TTCTGAAAGG CCTGAAGCAT TCCAACATCG TGCTCCTCCA TGACATCATC 480

CACACCAAGG AAACGCTGAC TCTGGTGTTT GAATACGTGC ATACAGACCT GTGTCAGTAC 540

ATGGACAAAC ACCCCGGGGG TCTCCATCCG GATAATGTGA AGCTGTTCCT GTTCCAGTTA 600

CTGAGAGGCC TCTCCTACAT CCACCAGAGG TACATCCTCC ACCGCGACCT CAAACCACAG 660

AACCTGCTCA TCAGCGACAC TGGAGAGCTC AAACTCGCTG ACTTTGGCCT GGCCAGGGCC 720

AAGTCGGTCC CCAGCCATAC CTACTCCAAC GAGGTGGTGA CCCTCTGGTA CCGGCCTCCA 780

GATGTCCTGC TGGGATCCAC GGACTACTCC ACCTGCCTGG ACATGTGGGG AGTGGGCTGC 840

ATTTTCATTG AGATGATCCA AGGGGTGGCT GCCTTTCCAG GGATGAAGGA CATCCAGGAC 900

CAGCTGGAGA GGATATTCCT GGTCATCGGC ACCCCCTCAG AGGACAGCTG GCCCGGCGTT 960

ACCTCTCTGC CTCACTTCAA ACCAGACCGC TTTACAGTTT ACAGCGCTAA GAAGCTCAGA 1020

CAAGCGTGGA ATAAGCTGGG CTACGTGGAC CATGCCGAGG AGTTGGCGAG CAGGTTCCTG 1080

CAGTGTTTCC CAAAGAACCG CCTGTCGGCC CAGGCGGCGC TGAACCACGA GTACTTCAGC 1140

AACCTTCCTC CGCGGCTCTG GGAGCTGCAG GACATGTCCT CTATCTTCAC CGGACCAAAT 1200

GTTAAGCTGC AGACAGAGAG CGGGGACAGC ATACAGGTGT GTGCACGACA GAACAGCCAT 1260

GGCAAGGCGT CCTCTGGCAG CAAGCACTGA 1290

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yeklek+geG+y++vyk+k+k +g++vAlK irl++e eg p+ta+rE sllk lkh+ni

Q: 95    YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHSNI  153

         99********************************998.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l+Lvfe++++dL ++++k++  +l++++vk +l+qll+gl+y+H++

Q: 154   VLLHDIIH-TKETLTLVFEYVHTDLCQYMDKHPG-GLHPDNVKLFLFQLLRGLSYIHQRY  211

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLis++g+lklaDfGlara s+p++ty++evvTlwYr+P++Llg+++Yst

Q: 212   ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTDYST  271

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

          +D+W+vgci+ e+++  + f+g ++ +dqlerif ++gtpse++wp+v++lp++k  +f

Q: 272   CLDMWGVGCIFIEMIQGVAAFPGMKDiQDQLERIFLVIGTPSEDSWPGVTSLPHFKpDRF  331

         ************************99679***************************8899

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

         + +++kkl++ ++kl   ++a +l +++l++ pk+R+sa++al+h+yf

Q: 332   TVYSAKKLRQAWNKLGyvDHAEELASRFLQCFPKNRLSAQAALNHEYF  379

         999*********99987677***************************9

Domain Sequence
(FASTA)

YEKLEKLGEG SYATVYKGKS KVNGKLVALK VIRLQEEEGT PFTAIREASL LKGLKHSNIV 60

LLHDIIHTKE TLTLVFEYVH TDLCQYMDKH PGGLHPDNVK LFLFQLLRGL SYIHQRYILH 120

RDLKPQNLLI SDTGELKLAD FGLARAKSVP SHTYSNEVVT LWYRPPDVLL GSTDYSTCLD 180

MWGVGCIFIE MIQGVAAFPG MKDIQDQLER IFLVIGTPSE DSWPGVTSLP HFKPDRFTVY 240

SAKKLRQAWN KLGYVDHAEE LASRFLQCFP KNRLSAQAAL NHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013