EKS-GAA-00507

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00507

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	404.7	2.0E-121	1	259	259

Status

Unreviewed

Ensembl Protein

ENSGACP00000019260

UniProt Accession

G3PNS7;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK1

Gene Synonyms/Alias

DAPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000014591	ENSGACP00000019260	ENSGACT00000019298

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

1409

Protein Sequence
(FASTA)

SGQFAVVRRC RHRGTGAEYA AKSIKKRRSK SSRRGVTRDD IEREVNILKE IQHPNVITLL 60

EVFENKAEVI LILELVAGGE LFDFLAEKES LSEEEATQFL KQILEGVFYL HTKQIAHFDL 120

KPENIMLLNR SVPHPRIKLI DFGLAHKIDF ESDSAQMSYY SAYCVCLTAP EVVNYEPLGL 180

EADMWSVGVI TYILLSGASP FLGDNKQETL ANVSAVDYAF DEEFFSSTSA LAKDFIARLL 240

VKDPKKRMTI QDSLQHPWIK PKDTQQALSR KESAVNMEKF KKFAARRKWK QSVRLISLCN 300

RLSRSFLSRS NISVARSDDT LDEEDSFVMK AIIHAINDDN VPGLQHLLGS LNSYDVNQPN 360

KHGTPPLLIA AGCGNIQIIE VLMRKGAEIQ ALDKSGTNAI YYAARHSHVE TLKFLHETKC 420

PLDVQDKSGE TALHVAARYG NVDVVSYLCS IRANPDLSDR EQETPLHCAA WHGYSPVARA 480

LCQAGCHVDA KNREGESALL TASARGFVDI VECLVEHGAD VEATDKDGHT ALHLAVRRCQ 540

VDVVRCLLRH RCHVDHQDRH GNTPLHIACK DGNLPVVMAI CSAKANLDLP NKYGRTPLHL 600

AANNGSLEVV RHLCLAGADV DVVTNDGKTA EDLAHADQHE LIVSLLGKLK KDNHKLSFIQ 660

QLRHTQTVQP RIKLKLFGHS GAGKSSLLES LKCGILRGLF RRKRTRLSSG SRHPNSPVNS 720

KPAVSASISN LYPGCENVSV RSRSMMFEPS LTKGVLEVFS PVSGALSAAD DQATKAIDIQ 780

HGSIHGVGEF SVWEFSGNPV YYCSYDYFAA NDATAIHLVL FSLEEPYETQ LGHITYWLNL 840

LKALLLPQDD IAFGGRVQQP LTVALVATHA DLADVPRAFS GEFTYDKEKA LLKEVRNRFG 900

SDLQISDKLF VMDAGASNSR DMKLLRSHLQ ELRANIISVS NPPPRPFQSC SPMTLLSERL 960

LTTLPAWRKL SGPNQLTSWQ QFVSDVQEQI NPLVSQDHLR TLALQLHSMG EINIMQSETV 1020

QDVVLLEPRW LCSTVLGKLL SVETPKAIHH YRGRYRLEEV QALAPESDVD ELLQILDAMD 1080

VCARDATNPS MVDIPALIKT NGLHRSWNSL LYGGVRLVPA EHLTPFPCGL FHKLQVNLCR 1140

WSHQQKPEEE GGEDFDGEIH LWTNGAKVSQ GGVEAMILLV NHGQGLEIQV RGHESERAKC 1200

YTLLDTACSI TENLLASTLP GLLTAKYYLS PQQLREHHGP IMVYQPKDFF RARVQRESSL 1260

TNTMGGYRES FSSILSFGCA EVYQQGTLGT DVHISDVPLL ARRKLCRMLD PPDALGKDWC 1320

LLAMNLGLTD LVATHGNGTP NGGPELDCAT ADPGQAAPQP SPTAALLRAW SGRADSTVGV 1380

LMAKLRELGR RDAADFLLKA SPVFRVNME 1409

Nucleotide Sequence
(FASTA)

AGCGGCCAGT TTGCTGTGGT CAGAAGATGC CGGCACAGGG GCACGGGCGC CGAGTACGCC 60

GCCAAATCCA TCAAGAAGCG CCGCAGCAAG TCGAGTCGGC GAGGCGTGAC GAGGGACGAC 120

ATCGAGCGCG AGGTGAACAT CCTGAAGGAG ATCCAGCACC CGAACGTCAT CACGCTCCTC 180

GAGGTGTTTG AGAACAAGGC GGAGGTGATC CTGATCCTGG AGCTCGTGGC CGGCGGCGAG 240

CTCTTTGACT TCCTGGCCGA GAAGGAGTCC CTGAGCGAGG AGGAGGCCAC CCAGTTCCTC 300

AAGCAGATCC TGGAGGGAGT CTTCTACCTG CACACCAAAC AAATCGCCCA CTTTGACCTT 360

AAGCCGGAAA ACATCATGCT GCTGAACCGC TCGGTGCCTC ATCCGCGCAT CAAGCTCATC 420

GACTTCGGCC TGGCACACAA GATCGACTTT GAATCGGACT CTGCTCAGAT GAGTTATTAC 480

TCTGCGTACT GTGTTTGCCT CACAGCTCCA GAGGTAGTCA ACTATGAACC TCTGGGCCTG 540

GAGGCAGACA TGTGGAGCGT CGGTGTGATA ACCTACATCC TTCTGAGCGG CGCGTCCCCC 600

TTCCTGGGGG ACAACAAGCA GGAGACTCTG GCCAACGTGT CGGCCGTGGA CTACGCGTTC 660

GACGAGGAGT TCTTCAGCAG CACCAGCGCG TTGGCCAAAG ACTTCATCGC CAGGCTCCTT 720

GTCAAAGACC CCAAGAAGAG AATGACGATT CAGGACAGCC TCCAGCACCC GTGGATCAAG 780

CCGAAGGACA CTCAACAAGC GCTGAGCAGG AAGGAGTCAG CCGTCAACAT GGAGAAGTTC 840

AAGAAGTTCG CAGCTCGGAG AAAATGGAAA CAATCCGTCC GACTCATCTC TCTGTGCAAC 900

CGCCTGTCCC GCTCCTTCCT GTCCAGGAGC AACATCAGCG TGGCGCGCAG CGACGACACG 960

CTGGACGAGG AAGACTCCTT CGTGATGAAG GCCATCATCC ACGCCATAAA CGACGACAAC 1020

GTGCCCGGTC TGCAGCACCT GCTCGGCTCC TTGAACAGCT ACGACGTTAA CCAGCCCAAC 1080

AAGCACGGGA CTCCTCCCCT CCTGATCGCG GCCGGCTGCG GCAACATTCA GATCATCGAA 1140

GTGCTGATGA GGAAAGGCGC CGAGATCCAG GCCCTCGACA AGAGTGGAAC GAACGCGATC 1200

TACTACGCAG CGAGACACAG CCACGTGGAG ACCCTGAAAT TCCTCCATGA AACGAAATGC 1260

CCTCTGGATG TCCAAGATAA GTCCGGGGAG ACTGCGCTTC ACGTGGCGGC CCGCTACGGC 1320

AACGTGGACG TGGTGAGCTA CCTGTGCAGC ATCCGAGCTA ACCCGGACCT GTCCGACAGG 1380

GAGCAGGAGA CGCCGCTGCA CTGCGCCGCG TGGCACGGGT ATTCGCCGGT GGCCCGAGCG 1440

CTCTGCCAGG CGGGCTGCCA CGTGGACGCC AAGAACCGCG AGGGGGAGAG CGCGCTGCTG 1500

ACGGCGTCCG CCCGGGGCTT CGTGGACATC GTGGAGTGCC TGGTGGAGCA CGGGGCCGAC 1560

GTCGAGGCCA CCGACAAGGA CGGACACACG GCGCTGCACC TCGCCGTCCG GAGGTGTCAA 1620

GTCGACGTGG TTCGCTGCCT CCTCAGACAC CGCTGCCACG TGGACCATCA GGATCGCCAT 1680

GGCAACACGC CGCTGCACAT CGCCTGCAAG GACGGAAACC TCCCCGTTGT CATGGCGATC 1740

TGCAGCGCCA AGGCCAACCT GGACCTGCCC AACAAGTACG GCAGGACCCC CCTCCACCTG 1800

GCGGCCAACA ACGGGAGCCT GGAGGTGGTC CGTCACCTCT GCCTGGCCGG AGCCGACGTG 1860

GACGTCGTCA CCAACGATGG AAAGACGGCG GAGGATTTGG CTCACGCCGA TCAACACGAG 1920

CTCATCGTTT CTTTGTTGGG GAAGCTTAAA AAGGACAACC ACAAGCTGAG CTTCATCCAG 1980

CAGCTGCGTC ACACTCAGAC CGTCCAGCCC CGCATCAAGC TGAAGCTGTT CGGACACTCG 2040

GGGGCCGGGA AGAGCAGCCT GCTGGAGTCC CTCAAGTGCG GCATCCTGCG CGGCCTCTTC 2100

AGGAGGAAGA GGACGCGCCT GTCCAGCGGC AGCCGCCACC CAAACTCCCC CGTCAACTCC 2160

AAACCCGCCG TGTCGGCGAG CATCTCCAAC CTGTACCCGG GCTGCGAGAA CGTGAGCGTG 2220

CGGAGCCGCA GCATGATGTT CGAGCCCAGT CTGACCAAAG GCGTCCTGGA GGTCTTCTCC 2280

CCCGTCAGCG GCGCCCTGTC CGCGGCCGAC GACCAGGCCA CCAAGGCCAT CGACATCCAG 2340

CACGGCAGCA TCCACGGGGT CGGGGAGTTC AGCGTGTGGG AGTTTTCGGG GAACCCGGTC 2400

TACTACTGCT CCTACGACTA CTTCGCCGCC AACGACGCCA CGGCGATCCA CCTGGTGCTG 2460

TTCAGCCTGG AGGAGCCGTA CGAGACGCAG CTGGGGCACA TCACCTACTG GCTGAACCTG 2520

CTGAAAGCCC TCCTGCTGCC GCAGGACGAC ATCGCCTTCG GGGGGCGGGT CCAGCAGCCC 2580

CTCACGGTCG CCCTGGTGGC GACGCACGCC GACCTCGCCG ACGTGCCCCG CGCCTTCTCC 2640

GGAGAGTTCA CCTACGACAA GGAGAAGGCC CTGCTCAAGG AAGTCAGGAA CAGGTTCGGC 2700

AGCGACCTGC AGATCAGTGA CAAACTATTT GTGATGGACG CCGGAGCCTC GAACTCCAGA 2760

GACATGAAGC TGCTGAGGAG TCACCTTCAG GAGCTCCGTG CCAACATCAT CTCTGTGAGC 2820

AACCCCCCCC CCCGCCCCTT CCAGAGCTGC AGTCCCATGA CGCTGCTGTC GGAGCGTCTG 2880

CTGACGACGC TGCCGGCCTG GAGGAAGCTG AGCGGACCCA ACCAGCTGAC CTCGTGGCAG 2940

CAGTTTGTGA GCGACGTCCA GGAGCAGATC AACCCTCTGG TCAGCCAGGA CCACCTGCGC 3000

ACCCTGGCCC TGCAGCTGCA CAGCATGGGG GAGATCAACA TCATGCAGAG CGAGACGGTG 3060

CAGGACGTCG TCCTGCTGGA GCCTCGCTGG CTCTGCAGCA CCGTCCTGGG CAAGCTGCTC 3120

TCCGTGGAGA CGCCCAAGGC CATCCACCAC TACAGGGGGC GCTACAGGCT GGAGGAGGTG 3180

CAGGCTCTGG CTCCCGAGAG CGACGTGGAC GAGCTGCTGC AGATCCTGGA CGCCATGGAC 3240

GTCTGCGCCC GCGACGCCAC CAACCCGTCC ATGGTGGACA TCCCCGCCCT CATCAAGACC 3300

AACGGCCTCC ACCGCTCCTG GAACTCGCTG CTCTACGGCG GCGTGCGCCT CGTCCCCGCC 3360

GAGCACCTCA CCCCCTTCCC CTGCGGCCTG TTTCACAAGC TGCAGGTGAA CCTGTGCCGC 3420

TGGAGCCACC AGCAGAAGCC GGAGGAGGAG GGCGGCGAGG ATTTCGACGG CGAGATCCAC 3480

CTGTGGACCA ACGGCGCCAA GGTGAGCCAG GGAGGAGTGG AGGCCATGAT CCTGCTGGTC 3540

AACCACGGCC AGGGGCTGGA GATCCAGGTG CGCGGGCACG AGTCCGAGCG GGCCAAGTGC 3600

TACACCCTGC TGGACACCGC CTGCAGCATC ACGGAGAACC TGCTGGCCTC CACGCTGCCC 3660

GGGCTGCTCA CCGCCAAATA CTACCTGAGC CCCCAGCAGC TGCGGGAGCA CCACGGCCCC 3720

ATCATGGTCT ACCAGCCCAA AGACTTCTTC CGCGCGCGAG TCCAGCGCGA GTCTTCGCTC 3780

ACCAACACCA TGGGCGGCTA CCGCGAGAGC TTCAGCAGCA TCCTGTCCTT CGGCTGCGCC 3840

GAGGTCTACC AGCAGGGCAC CCTGGGGACG GACGTCCACA TATCGGACGT GCCGCTGTTG 3900

GCCCGCAGGA AGCTGTGCCG CATGCTGGAC CCCCCGGACG CGCTGGGCAA AGACTGGTGC 3960

CTGCTCGCCA TGAACCTCGG CCTCACCGAC CTGGTGGCCA CACACGGCAA CGGGACCCCC 4020

AACGGCGGCC CCGAGCTGGA CTGTGCGACG GCGGACCCCG GGCAGGCCGC GCCGCAGCCC 4080

AGCCCGACCG CGGCGCTGCT GCGGGCGTGG AGCGGGCGGG CGGACAGCAC CGTGGGCGTT 4140

CTGATGGCCA AGCTGAGGGA GCTCGGCCGA CGGGACGCCG CCGACTTCCT GCTCAAAGCG 4200

TCGCCCGTGT TCAGGGTCAA CATGGAG 4227

Domain Profile

S: 9     sGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirsepnvinl  68

         sG+favvr+cr++ tG eyaak +kkrr+kssrrgv+r++ierev++lkei+ +pnvi+l

Q: 1     SGQFAVVRRCRHRGTGAEYAAKSIKKRRSKSSRRGVTRDDIEREVNILKEIQ-HPNVITL  59

         69**************************************************.*******

S: 69    hevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylhskkivhld  128

          ev+enk++vililelvaGGelfd+laekeslseeeat++lkqilegv ylh+k+i+h+d

Q: 60    LEVFENKAEVILILELVAGGELFDFLAEKESLSEEEATQFLKQILEGVFYLHTKQIAHFD  119

         ************************************************************

S: 129   lkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefv....aPeivnyepls  184

         lkPeni+ll+++vp+++iklidfGl++ki+  ++  ++     +     aPe+vnyepl+

Q: 120   LKPENIMLLNRSVPHPRIKLIDFGLAHKIDFESDSAQMSYYSAYCvcltAPEVVNYEPLG  179

         **********************************9999998888434459**********

S: 185   letdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfirrl  244

         le+dmws+GvityillsgasPflGd+kqetl+n+sav++ f+ee+fss+s lakdfi rl

Q: 180   LEADMWSVGVITYILLSGASPFLGDNKQETLANVSAVDYAFDEEFFSSTSALAKDFIARL  239

         ************************************************************

S: 245   lvkdpekrltieeclehswl  264

         lvkdp+kr+ti+++l+h+w+

Q: 240   LVKDPKKRMTIQDSLQHPWI  259

         *******************8

Domain Sequence
(FASTA)

SGQFAVVRRC RHRGTGAEYA AKSIKKRRSK SSRRGVTRDD IEREVNILKE IQHPNVITLL 60

EVFENKAEVI LILELVAGGE LFDFLAEKES LSEEEATQFL KQILEGVFYL HTKQIAHFDL 120

KPENIMLLNR SVPHPRIKLI DFGLAHKIDF ESDSAQMSYY SAYCVCLTAP EVVNYEPLGL 180

EADMWSVGVI TYILLSGASP FLGDNKQETL ANVSAVDYAF DEEFFSSTSA LAKDFIARLL 240

VKDPKKRMTI QDSLQHPWI 259

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR000488	; Death.
IPR020676	; Death-assoc_prot_kinase.
IPR011029	; DEATH-like.
IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00023	; Ank; 1.
PF12796	; Ank_2; 2.
PF00531	; Death; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00248	; ANK; 8.
SM00005	; DEATH; 1.
SM00220	; S_TKc; 1.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 7.
PS50017	; DEATH_DOMAIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01415

; ANKYRIN.

Created Date

20-Feb-2013