EKS-GAA-00571

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00571

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	356.0	1.8E-106	91	376	286

Status

Unreviewed

Ensembl Protein

ENSGACP00000019592

UniProt Accession

G3PPQ7;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000014837	ENSGACP00000019592	ENSGACT00000019630

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

473

Protein Sequence
(FASTA)

MAFHGGGRQT VCGDLFPGSE LGHKYFCVNS SCGAPSTGLS ATPCLSGPTA PAGTPRHPAA 60

MGGSTGGGAA VPQPYSNPAS EVPSPAEMEP DRPIGYGAFG VVWSVTDPRD GRKVALKKMP 120

NVFQNLVSCK RVFRELRMLC FFKHDNVLSA LDILQPPQID CFEEIYVITE LMQSDLHKVI 180

VSPQPLTTDH IKVFLYQILR GLKYLHSAGI LHRDIKPGNL LVNSNCLLKI CDFGLARVEE 240

PDPTRHMTQE VVTQYYRAPE VLMGCRHYGS AIDVWSVGCI FAELLGRRIL FQAQSPIQQL 300

DLITDLLGTP PLSALSSACE GARAHILRGP HKPLSLSVLY MLSDGATHEV HLLCRMLVFD 360

PAKRISGSDA LSHPYLEGRL RYHTCMCQCC YSVPSGRVYT RDFEPVAERP FSHSYENSLL 420

SVWQGKELIH RFISEHQQGK RVPLCINPQS AAFKTFIRST AWHSSKVSRK EER 473

Nucleotide Sequence
(FASTA)

ATGGCGTTCC ACGGCGGCGG CCGGCAGACC GTCTGCGGGG ACTTGTTTCC GGGCTCCGAG 60

TTGGGCCACA AGTATTTCTG CGTGAACTCG TCTTGCGGCG CCCCGTCCAC GGGCCTCAGT 120

GCCACGCCGT GCCTAAGCGG ACCCACCGCT CCGGCCGGGA CGCCCCGCCA CCCCGCAGCC 180

ATGGGGGGCA GCACCGGGGG GGGAGCGGCG GTGCCTCAGC CCTACAGCAA CCCGGCCAGC 240

GAGGTGCCGA GCCCGGCTGA GATGGAGCCC GACCGGCCCA TCGGCTACGG GGCCTTTGGG 300

GTCGTCTGGT CCGTCACGGA TCCTCGAGAC GGGCGTAAAG TGGCCCTGAA GAAGATGCCC 360

AACGTCTTCC AGAACCTGGT CTCGTGTAAG CGGGTCTTCA GAGAGCTGCG GATGCTCTGC 420

TTCTTCAAAC ACGACAACGT TTTGTCGGCG TTGGACATTC TGCAGCCGCC ACAAATCGAC 480

TGCTTTGAGG AAATCTACGT GATCACGGAG CTGATGCAGA GCGACCTCCA CAAAGTGATC 540

GTGTCTCCTC AGCCGCTCAC CACCGACCAC ATCAAGGTCT TCCTCTACCA GATCCTCAGA 600

GGTCTGAAGT ACCTTCACTC CGCTGGGATT CTGCACCGAG ACATCAAACC TGGAAACCTG 660

CTGGTCAACA GCAACTGTCT GCTGAAGATC TGTGACTTCG GCCTGGCGCG TGTGGAGGAG 720

CCCGACCCGA CCCGTCACAT GACCCAGGAG GTGGTGACCC AGTACTACCG GGCCCCGGAG 780

GTGCTGATGG GCTGCCGGCA CTACGGATCG GCCATCGACG TCTGGTCGGT GGGCTGCATC 840

TTCGCAGAGC TGCTGGGCCG CCGCATCCTC TTCCAGGCCC AAAGCCCCAT TCAGCAGCTG 900

GATCTGATCA CAGACCTGCT AGGAACGCCC CCCCTGTCGG CCCTGTCGTC GGCCTGTGAG 960

GGGGCCAGAG CTCACATCCT CAGGGGGCCA CACAAACCGC TCTCGCTGTC GGTGCTCTAC 1020

ATGCTGTCGG ACGGGGCCAC GCACGAGGTG CACCTGCTCT GCCGCATGCT GGTGTTCGAC 1080

CCGGCCAAGC GGATCTCCGG CAGCGACGCC CTGTCCCACC CCTACCTTGA GGGCCGCCTG 1140

CGCTACCACA CCTGCATGTG CCAGTGCTGC TACTCCGTCC CCAGCGGGCG CGTGTACACC 1200

CGCGACTTCG AGCCGGTGGC TGAGCGCCCG TTCAGCCACA GCTACGAGAA CAGCCTGCTG 1260

TCCGTGTGGC AGGGCAAAGA GTTGATCCAT CGCTTCATCA GCGAGCACCA GCAGGGAAAG 1320

CGTGTGCCGC TGTGCATCAA CCCCCAGAGC GCCGCCTTCA AGACCTTCAT CAGGTCCACT 1380

GCATGGCATT CCTCCAAGGT GTCAAGGAAG GAGGAGAGAT GA 1422

Domain Profile

S: 4     lkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNiikl  63

          +p+g Ga+gvv+s++d r++++va+kk+ ++fq+ +s+kr++REl++l  +kh+N+++

Q: 91    DRPIGYGAFGVVWSVTDPRDGRKVALKKMPNVFQNLVSCKRVFRELRMLCFFKHDNVLSA  150

         689*********************************************************

S: 64    ldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylHsan  122

         ld+++p + ++ ++++Y++telm++dL+kvi s   l+ +hik++lyqilrglkylHsa+

Q: 151   LDILQPPQ-IDCFEEIYVITELMQSDLHKVIVSPqPLTTDHIKVFLYQILRGLKYLHSAG  209

         *******9.*********************999879************************

S: 123   viHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslkeyt  182

         ++HrD+KP+Nllvn++c lki+dFGlar+++++ ++++t++v+t++YraPe+l+  ++y

Q: 210   ILHRDIKPGNLLVNSNCLLKICDFGLARVEEPDPTRHMTQEVVTQYYRAPEVLMGCRHYG  269

         ************************************************************

S: 183   kavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyiks  242

         +a+D+WsvGCI+aEll +++lf++++ i+ql++i+++lgtp  + l++ ++  ar++i +

Q: 270   SAIDVWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPPLSALSSACEG-ARAHILR  328

         *************************************************996.8888888

S: 243   lpkkkkk.dfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

          p+k+   ++  ++++  ++ ++Ll ++Lv+dp kRis ++aL+hpYl

Q: 329   GPHKPLSlSVLYMLSDGATHEVHLLCRMLVFDPAKRISGSDALSHPYL  376

         887765437777788899999**************************7

Domain Sequence
(FASTA)

DRPIGYGAFG VVWSVTDPRD GRKVALKKMP NVFQNLVSCK RVFRELRMLC FFKHDNVLSA 60

LDILQPPQID CFEEIYVITE LMQSDLHKVI VSPQPLTTDH IKVFLYQILR GLKYLHSAGI 120

LHRDIKPGNL LVNSNCLLKI CDFGLARVEE PDPTRHMTQE VVTQYYRAPE VLMGCRHYGS 180

AIDVWSVGCI FAELLGRRIL FQAQSPIQQL DLITDLLGTP PLSALSSACE GARAHILRGP 240

HKPLSLSVLY MLSDGATHEV HLLCRMLVFD PAKRISGSDA LSHPYL 286

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Gadus morhua"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013