EKS-GAA-00316

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00316

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	248.3	1.0E-73	47	308	262

Status

Unreviewed

Ensembl Protein

ENSGACP00000020071

UniProt Accession

G3PR36;

Protein Name

Protein Synonyms/Alias

Gene Name

STK11

Gene Synonyms/Alias

STK11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000015219	ENSGACP00000020071	ENSGACT00000020110

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

440

Protein Sequence
(FASTA)

MSAGELQHLD YLNENELMEM DTFIHRIDST EVIYQPRRKR AKLIGKYLMG DLLGEGSYGK 60

VKEMLDSDTL CRRAVKILKK KKLRRIPNGE ANVKKEIQLL RRLQHKNVIQ LVDVLYNEEK 120

QKIYYMVMEY CVCGMQEMLD SVPEKRFPVF QAHGYFSQLL DGLEYLHSQG IVHKDIKPGN 180

LLLTTDGALK ISDLGVAEAL HPFAEDDTCR TSQGSPAFQP PEIANGLDTF SGFKVDIWSA 240

GVTLYNITTS LYPFEGDNIY KLFENIGKGD YTIPEECGPL LSDLLQGMLE YDPEKRFSIQ 300

NIRKHNWVRK KHPPSELPVP IPANAESRDP WRSMTVVPYL EDLHGYTEED DDDLYDGEDE 360

IIYTQDFTVP GQVAEEEDLD QGHEDHSPSL AKPVCVNGTE GGSLNSKAKA ERRSSSSSNP 420

SRKGVSTASK IRKLSTCKQQ 440

Nucleotide Sequence
(FASTA)

ATGAGTGCCG GCGAGCTGCA ACATCTTGAC TATCTAAATG AAAATGAGCT GATGGAGATG 60

GATACTTTCA TTCATCGCAT TGACTCTACG GAGGTGATCT ACCAGCCAAG GAGGAAGAGG 120

GCAAAGCTGA TAGGAAAGTA CTTGATGGGA GATCTGCTAG GTGAGGGATC TTATGGCAAA 180

GTGAAAGAGA TGCTGGACTC GGATACACTT TGTCGCAGGG CTGTCAAAAT ACTGAAGAAG 240

AAGAAACTGA GGAGGATTCC CAACGGAGAA GCCAATGTGA AAAAGGAGAT TCAGCTACTA 300

AGAAGACTCC AACACAAGAA TGTGATTCAG TTGGTGGACG TGCTCTACAA CGAAGAGAAG 360

CAGAAAATAT ATTATATGGT GATGGAGTAT TGCGTTTGTG GGATGCAAGA AATGCTGGAC 420

AGCGTCCCAG AAAAAAGGTT TCCAGTATTT CAAGCTCACG GGTACTTTAG CCAACTCTTG 480

GATGGCCTCG AATATTTGCA CAGCCAGGGA ATAGTTCACA AAGACATTAA ACCAGGAAAT 540

CTGCTGCTGA CCACAGACGG AGCACTTAAA ATCTCTGACC TGGGAGTAGC AGAGGCCCTT 600

CACCCATTTG CAGAGGACGA TACGTGTCGA ACCAGTCAGG GCTCGCCGGC CTTCCAGCCT 660

CCAGAGATCG CAAATGGACT GGACACCTTT TCAGGGTTTA AAGTGGACAT TTGGTCCGCT 720

GGAGTAACAC TATACAACAT CACAACGAGT TTGTATCCGT TTGAGGGAGA CAACATCTAT 780

AAGCTATTTG AGAACATTGG AAAAGGAGAC TACACTATTC CCGAGGAGTG TGGACCGCTC 840

CTGTCGGACC TGCTGCAAGG GATGCTTGAG TATGACCCTG AAAAGAGGTT TTCCATACAG 900

AACATAAGGA AACATAACTG GGTGCGTAAG AAACACCCTC CGTCTGAGCT CCCTGTGCCC 960

ATCCCTGCCA ACGCGGAGAG CAGGGATCCC TGGCGGAGTA TGACGGTGGT GCCCTACCTG 1020

GAGGATCTCC ACGGCTACAC AGAGGAGGAC GATGATGACC TCTACGATGG AGAGGATGAG 1080

ATCATATACA CTCAGGACTT CACAGTGCCA GGACAAGTGG CCGAAGAAGA AGATCTGGAT 1140

CAGGGGCACG AAGACCACAG TCCATCTCTA GCCAAGCCGG TTTGTGTAAA CGGGACAGAG 1200

GGGGGGTCTC TGAATAGCAA GGCCAAAGCC GAACGCCGAT CCTCCTCTTC ATCCAACCCC 1260

TCGCGTAAAG GGGTCTCCAC AGCCAGCAAG ATCCGCAAGC TCTCCACCTG CAAACAGCAA 1320

TGA 1323

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl..seeslekikrEieilkklkhp  58

         y +++ lGegs+gkVk++ +++t  + avKi+kkkkl    +   ++k+Ei++l++l+h+

Q: 47    YLMGDLLGEGSYGKVKEMLDSDTLCRRAVKILKKKKLrrIPNGEANVKKEIQLLRRLQHK  106

         778999******************************965334567***************

S: 59    niikllevi...etkkklylvleyasgg..eLfdyieekgrlkekearklfkqlvsavkY  113

         n+i+l++v+   e++k +y+v+ey+  g  e++d +  ++r++  +a+ +f+ql+++++Y

Q: 107   NVIQLVDVLyneEKQKIYYMVMEYCVCGmqEMLDSV-PEKRFPVFQAHGYFSQLLDGLEY  165

         ********97766677799*****998888*****6.8899*******************

S: 114   lhskgivHrDlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPellk  170

         lhs+givH+D+Kp Nlll++++ +ki+D+G+a+    f e+++++t++Gsp++++Pe+ +

Q: 166   LHSQGIVHKDIKPGNLLLTTDGALKISDLGVAEalhPFAEDDTCRTSQGSPAFQPPEIAN  225

         ********************************966567788******************9

S: 171   g.kkYegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLl  229

         g ++++g kvD+Ws+Gv+Ly++ t  +Pf+++n+ +l+e+i kg+++ip+++ + l++Ll

Q: 226   GlDTFSGFKVDIWSAGVTLYNITTSLYPFEGDNIYKLFENIGKGDYTIPEECGPLLSDLL  285

         9899********************************************************

S: 230   rklLvvdpekRatieeilkhewl  252

         + +L+ dpekR++i++i+kh+w+

Q: 286   QGMLEYDPEKRFSIQNIRKHNWV  308

         **********************7

Domain Sequence
(FASTA)

YLMGDLLGEG SYGKVKEMLD SDTLCRRAVK ILKKKKLRRI PNGEANVKKE IQLLRRLQHK 60

NVIQLVDVLY NEEKQKIYYM VMEYCVCGMQ EMLDSVPEKR FPVFQAHGYF SQLLDGLEYL 120

HSQGIVHKDI KPGNLLLTTD GALKISDLGV AEALHPFAED DTCRTSQGSP AFQPPEIANG 180

LDTFSGFKVD IWSAGVTLYN ITTSLYPFEG DNIYKLFENI GKGDYTIPEE CGPLLSDLLQ 240

GMLEYDPEKR FSIQNIRKHN WV 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013