EPS-GAA-00050

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAA-00050

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	158.5	3.6E-46	784	1031	248

Status

Unreviewed

Ensembl Protein

ENSGACP00000020839

UniProt Accession

G3PTA3;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000015791	ENSGACP00000020839	ENSGACT00000020879

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

1310

Protein Sequence
(FASTA)

MKRNGSRGCV TRKNRFGSRE RDWLKGDTQR GCVCLYGGTV DPQPPASGPQ ASSTPQTDLQ 60

LVLCSTTTTV EELCAQRDGH GLYVQLHGDL VRRLDPTERP LQMLYDYLAA MGYAEPVRVQ 120

QEAANSDLSC LIRFYSEPPV NADQQERTLL KGIFNVRKGK SQLHKWAERQ VILCGTCLIV 180

ASVKDSLTGK MHILPLVGGK VEEVKRRQHC LMFSSAGSQA QTYFVNFDAL ADYQRWHRQA 240

SKVVSQTVSL VDLSCYSLEV VPEYLFYSQD ITHLNLRHNF MSLQGPGGLL NLPKFSQLKS 300

LNLSHNRLGV FPECVCEILT LTELNLSCNS LLTVPVQIGN LQSLQILSLD GNHLSSLPED 360

LGGLSQLNSL GLSFNNFSHI PAVLERLSAV DKLAMAGNTV ESLELCTLAR MSHLKNIDLR 420

LNRLHCVKSE SLEAVSQVTQ LDLRDNCLDS LDLSSVCNLE TLHCQRNQLG TLTLSGFTLR 480

MLHASSNRLP TVNIYPVPNQ LTSLDLSQNL LEYLPDWVCD CRKIEMLDVT HNLLSELPSR 540

LLNSLSLRKL LAGNNCLQRV PDLLDHIPLE ALDLQHNKLA ELPESLFYKA LNLKYLNVSA 600

NALDSIPPSS PSEESLSTLQ ELYLTANHLK ENCGALLVGH QNLRVLHIAY NQLLSFPASK 660

LSKLEMLEEL NLSGNKLKAI PSTVSSCKRL HTLIAHSNHI TVFPEILNLP EIKLVDLSCN 720

ELTEIQLPDS LPSTLQELDL TGNSSLMLEH KTLNLFSHIT TLKLDQKSTT SVGDSQSGST 780

PWNHGYSEMS GQRNKDRLCV SVLAVDRFGD GVEACYGIFD GDRNEEVPRL LQCTMGDVLC 840

EELQHSSIDS VYMCNTFLTS HRKLGMAGQK LGASALLCYI HHEPSDPGSY FSLTVANVGT 900

CQAVLCRDGR PVPLSKVYSL ENSTEEMERV KLSKAIITED NKVSGVTCCS RLLGCSYLSP 960

WVLPKPWVHT EPLCTKDEFL ILGNRALFER VSYQEAVCTV QAVRDPRAAA KKLCSLAQSY 1020

GCKDNIEAAV VSLHIVEDSC TCEPPVPSTE PRCPPPIATV TPGPTDPVAP SSNCGIVSEC 1080

NGEASTSEVG GEAGSTAPDE HPSSVLASRP ERRCSLHPAT TLCGIMVPGA VGAGTHLGLF 1140

QRQPSCTTFS SNHSDNGLDS DDEAPLEGVI SNGSKLEVEV DIHCCAFQLR SGAPESSKDL 1200

ELKKRGSDYP NGKMRRQNSV VVSATNGCLL AVCGREIADL KKSPSTSSLF GKKLSNGSVV 1260

APEDSHNLIE VALEAPKKKS GYFTAPAQQD PEDQLIVPPS LEQEVREQLR 1310

Nucleotide Sequence
(FASTA)

ATGAAGAGGA ACGGGAGTCG TGGCTGCGTG ACGAGAAAAA ACAGATTTGG ATCAAGAGAG 60

CGGGACTGGC TAAAGGGGGA CACCCAGCGG GGCTGTGTGT GTCTGTATGG GGGGACAGTG 120

GACCCCCAGC CACCTGCATC TGGTCCACAA GCCTCCTCCA CCCCCCAAAC AGACCTGCAG 180

TTGGTGCTCT GCTCCACCAC CACCACAGTG GAGGAACTGT GCGCTCAGAG GGACGGACAT 240

GGACTCTATG TTCAGCTGCA CGGAGACCTG GTCAGGCGGC TGGACCCCAC CGAGCGCCCG 300

CTCCAGATGC TGTACGACTA CCTGGCGGCT ATGGGCTACG CAGAGCCTGT GCGAGTGCAG 360

CAAGAAGCCG CCAACTCAGA CCTCAGCTGT TTGATCCGTT TCTACAGTGA GCCTCCCGTG 420

AATGCAGACC AGCAGGAGAG GACACTGCTG AAAGGAATAT TCAACGTCCG GAAGGGCAAG 480

TCGCAGCTGC ACAAGTGGGC CGAGCGGCAG GTCATCCTCT GCGGCACCTG TCTAATTGTG 540

GCCTCCGTCA AAGACAGCCT GACCGGGAAG ATGCACATCC TGCCCCTTGT GGGGGGAAAG 600

GTGGAGGAGG TGAAGCGGAG GCAGCACTGT CTGATGTTCA GCTCAGCCGG ATCTCAGGCC 660

CAGACATACT TTGTCAACTT TGACGCACTG GCAGACTACC AGCGGTGGCA TCGGCAGGCA 720

TCAAAAGTGG TGTCTCAGAC AGTCAGCCTG GTGGACCTGT CGTGCTACAG TCTGGAAGTA 780

GTGCCTGAAT ATCTCTTTTA CAGTCAGGAC ATCACCCACC TCAACCTGAG GCACAACTTC 840

ATGAGCCTTC AGGGGCCCGG GGGTCTGCTC AACCTGCCCA AGTTTTCACA GCTGAAGAGC 900

CTGAACTTGT CTCACAACCG GTTGGGTGTG TTCCCCGAAT GTGTGTGTGA GATCCTCACC 960

CTGACTGAAC TCAACCTCTC CTGTAACAGT CTCCTAACAG TCCCTGTGCA GATCGGCAAC 1020

CTTCAAAGCC TGCAGATACT GTCTTTGGAT GGAAACCATC TCAGCTCCCT GCCCGAAGAT 1080

CTGGGGGGCC TGTCCCAGCT CAACAGCCTG GGGCTTTCCT TTAACAACTT CTCTCACATC 1140

CCCGCTGTGC TGGAGAGGCT GAGTGCAGTG GACAAGCTGG CCATGGCTGG GAACACAGTG 1200

GAGAGTCTGG AGTTGTGTAC TCTGGCCAGA ATGAGCCACC TGAAAAACAT CGACCTCCGA 1260

TTGAACAGGC TGCATTGCGT GAAAAGTGAG AGTCTAGAGG CAGTGAGCCA GGTGACCCAG 1320

CTGGATTTAC GGGACAATTG TTTGGACTCC TTGGACCTGA GCTCCGTCTG CAACCTGGAG 1380

ACTCTGCACT GCCAGCGCAA CCAGCTCGGA ACACTCACAC TCAGCGGTTT CACACTGCGC 1440

ATGCTTCACG CCAGCAGCAA CCGACTTCCA ACAGTCAACA TCTATCCAGT CCCTAACCAG 1500

CTGACATCCT TGGACCTATC ACAGAACCTT TTGGAGTACC TTCCGGACTG GGTGTGTGAT 1560

TGCAGAAAAA TTGAGATGCT GGACGTTACG CACAACCTCC TGTCTGAGCT CCCGTCCAGA 1620

CTGCTCAACA GCTTGAGTTT GAGAAAGCTG CTGGCGGGGA ACAACTGTTT GCAGAGAGTG 1680

CCTGACCTAC TTGACCACAT CCCTCTGGAA GCCCTGGACC TCCAGCACAA CAAGCTAGCC 1740

GAGCTCCCTG AGAGTCTGTT CTACAAGGCC TTAAACCTAA AATACTTAAA TGTGTCAGCC 1800

AATGCCCTGG ACAGCATTCC TCCCAGCAGC CCATCCGAGG AGAGCCTCAG CACGCTCCAA 1860

GAGCTCTACC TGACGGCCAA CCACCTGAAG GAGAACTGCG GAGCTCTGTT GGTTGGACAT 1920

CAGAACCTGC GGGTCCTTCA TATCGCCTAC AACCAGCTGC TCTCCTTCCC GGCCAGTAAA 1980

CTGAGTAAGC TGGAAATGCT GGAGGAGCTC AATCTAAGTG GCAACAAGCT AAAGGCCATC 2040

CCCTCCACTG TGTCCAGCTG TAAGAGACTG CACACCCTCA TTGCACACTC CAACCACATC 2100

ACTGTCTTTC CAGAGATCCT CAACCTCCCT GAGATCAAGC TTGTAGATCT CAGCTGTAAC 2160

GAGCTGACGG AGATCCAGCT GCCAGACTCG CTGCCTTCCA CTCTGCAAGA GCTGGACCTG 2220

ACGGGCAACA GCAGCCTGAT GCTGGAACAC AAAACCCTCA ATCTCTTCAG TCACATCACC 2280

ACCTTGAAAT TAGACCAGAA ATCCACCACG TCAGTGGGAG ACTCACAGAG TGGATCCACT 2340

CCATGGAACC ACGGTTACTC TGAAATGAGC GGCCAAAGAA ACAAGGACAG GTTGTGTGTG 2400

TCTGTACTGG CCGTGGACCG GTTTGGAGAC GGTGTGGAAG CATGTTATGG CATCTTTGAC 2460

GGCGACCGCA ATGAGGAAGT ACCTCGGCTG CTGCAATGCA CCATGGGAGA TGTGCTATGC 2520

GAGGAACTGC AGCACTCCAG TATTGACAGT GTGTATATGT GCAACACTTT CCTCACCTCA 2580

CACAGGAAAC TAGGAATGGC TGGCCAGAAA CTGGGTGCTT CTGCCTTGCT GTGTTATATT 2640

CACCATGAGC CTTCAGATCC AGGAAGCTAC TTCAGCCTCA CCGTGGCCAA TGTGGGCACC 2700

TGCCAGGCAG TTTTGTGCCG GGACGGGCGA CCTGTACCTC TCTCTAAGGT CTACAGCTTG 2760

GAGAACTCCA CCGAGGAGAT GGAGAGGGTT AAGCTCAGTA AAGCCATTAT TACCGAGGAT 2820

AACAAGGTGA GTGGAGTGAC ATGCTGCTCT CGCCTGCTGG GCTGCTCTTA TCTGTCTCCC 2880

TGGGTGCTTC CAAAGCCCTG GGTGCACACT GAGCCTCTCT GTACCAAGGA TGAGTTCTTG 2940

ATCCTGGGGA ATCGAGCGCT GTTTGAACGG GTCTCGTACC AGGAGGCCGT GTGCACTGTG 3000

CAGGCCGTGC GGGATCCTCG CGCCGCCGCC AAGAAGCTGT GCTCACTCGC TCAGAGTTAC 3060

GGTTGCAAGG ACAACATCGA GGCTGCGGTG GTATCCCTGC ATATCGTTGA GGACAGCTGT 3120

ACCTGTGAGC CACCGGTCCC CTCCACCGAA CCACGGTGTC CCCCTCCCAT CGCTACTGTG 3180

ACCCCGGGGC CCACTGACCC AGTCGCCCCG TCGTCCAACT GCGGCATCGT CTCCGAGTGC 3240

AACGGTGAGG CATCAACCTC CGAGGTGGGC GGCGAGGCCG GGTCCACCGC TCCGGACGAG 3300

CACCCGTCGT CTGTGCTGGC ATCGCGCCCG GAGCGGCGCT GTAGCCTTCA CCCTGCCACT 3360

ACACTGTGTG GCATCATGGT GCCGGGCGCA GTTGGGGCAG GAACCCATCT GGGTCTATTC 3420

CAGCGGCAGC CGTCCTGCAC CACTTTCTCA AGCAACCACT CCGACAACGG CTTGGACAGT 3480

GACGACGAAG CTCCACTCGA GGGCGTTATC TCCAATGGCA GCAAGTTGGA AGTGGAGGTT 3540

GACATTCACT GTTGTGCTTT CCAACTACGC TCGGGGGCCC CTGAAAGCTC CAAAGACTTG 3600

GAGCTCAAAA AGCGAGGCTC TGACTATCCC AATGGCAAAA TGCGAAGACA GAACAGCGTG 3660

GTGGTTTCTG CCACAAACGG CTGCCTTCTG GCCGTGTGCG GGAGAGAGAT TGCAGACCTC 3720

AAAAAGTCTC CTTCCACATC CAGCCTGTTT GGGAAGAAAC TGTCCAACGG CTCTGTGGTG 3780

GCCCCCGAGG ACAGTCACAA CCTCATCGAG GTGGCACTGG AGGCTCCGAA GAAGAAATCC 3840

GGCTACTTCA CTGCCCCAGC ACAACAGGAC CCCGAGGACC AGCTCATTGT GCCTCCCAGT 3900

TTGGAGCAGG AGGTCAGGGA GCAGCTGAGA 3930

Domain Profile

S: 3     vgvvsvngrr..nemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklhei  60

         +g+++++g+r  + ++ +v ++++f++  e+      +g++DG++++ev + +++++ ++

Q: 784   HGYSEMSGQRnkDRLCVSVLAVDRFGDGVEA-----CYGIFDGDRNEEVPRLLQCTMGDV  838

         6777777776325688888888889887764.....8***********************

S: 61    laeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds.....  115

         l eel+    ++   + ++ ++Fl+ +++l       ++ +k G++a++++i ++

Q: 839   LCEELQ----HSSIDSVYMCNTFLTSHRKL------GMAGQKLGASALLCYIHHEpsdpg  888

         ****99....66666778************......89***************9999***

S: 116   ...klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGv  171

            +l+vanvG ++avLcr+g +v+ls+ ++ +++ +E+eR++  ++ +++++  +v Gv

Q: 889   syfSLTVANVGTCQAVLCRDGRPVPLSKVYSLENStEEMERVKLSKAIITEDN--KVSGV  946

         ********************************99879*********9999998..*****

S: 172   LavsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlek  231

         +++sR lG+ yl+p+v p+P v+  +l  +defliL+   l++ vs +eav  v+ v +

Q: 947   TCCSRLLGCSYLSPWVLPKPWVHTEPLCTKDEFLILGNRALFERVSYQEAVCTVQAVRD-  1005

         ***********************************************************.

S: 232   keaeqeaakkLvklalargskdnvsaivv  260

            +++aakkL+ la+++g+kdn+ a vv

Q: 1006  ---PRAAAKKLCSLAQSYGCKDNIEAAVV  1031

         ...*********************98876

Domain Sequence
(FASTA)

HGYSEMSGQR NKDRLCVSVL AVDRFGDGVE ACYGIFDGDR NEEVPRLLQC TMGDVLCEEL 60

QHSSIDSVYM CNTFLTSHRK LGMAGQKLGA SALLCYIHHE PSDPGSYFSL TVANVGTCQA 120

VLCRDGRPVP LSKVYSLENS TEEMERVKLS KAIITEDNKV SGVTCCSRLL GCSYLSPWVL 180

PKPWVHTEPL CTKDEFLILG NRALFERVSY QEAVCTVQAV RDPRAAAKKL CSLAQSYGCK 240

DNIEAAVV 248

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>