EKS-GAA-00302

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00302

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.8	2.4E-101	26	278	253

Status

Unreviewed

Ensembl Protein

ENSGACP00000021019

UniProt Accession

G3PTT2;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000015926	ENSGACP00000021019	ENSGACT00000021059

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

582

Protein Sequence
(FASTA)

TPQQGHCGKM ATEKQKNEGR VKIGHYILGD TLGVGTFGKV KVGQHELTKH QVAVKILNRQ 60

KIRSLDVVGK IRREIQNLKL FRHPHIIKLY QVISTPTDIF MVMEYVSGGE LFDYICKNGK 120

LDEKESRRLF QQIISAVDYC HRHMVVHRDL KPENVLLDAH MNAKIADFGL SNMMSDGEFL 180

RTSCGSPNYA APEVISGRLY AGPEVDIWSS GVILYALLCG TLPFDDDHVP TLFKKICDGI 240

FFTPQYLNPS VISLLKHMLQ VDPMKRATIK EIREDEWFKQ GLPKYLFPED PSYSNNMIDD 300

EALKEVCDKF ECTEEEVLTC IYSRNHQDPL AVAYHLIIDN RRIMNEAKDF YLASSPPDSF 360

LDDQHLTASG ASVSGIVKVH PERVPFLLAE TPPRPRHTLD ELNPQKSKHQ GVRRAKWHLG 420

IRSQSRPNDI MSEVCRAMKQ LDYEWKVVNP YYLRVRRKNP VTGMQTKMSL QLYQVDSRTY 480

LLDFRSIDDD MLETKSGTAT PLRSGSVGNY RTTIKNDVDG PDAQAASSTV LPTKAAEGSL 540

ASSLTSSIES TGGADTPTVP RPGSHTIEFF EMCANLIKLL AR 582

Nucleotide Sequence
(FASTA)

ACCCCGCAGC AAGGCCACTG CGGGAAGATG GCGACGGAAA AACAGAAAAA TGAAGGAAGA 60

GTTAAGATTG GACATTACAT TCTCGGAGAT ACACTCGGCG TGGGCACGTT TGGAAAGGTT 120

AAAGTTGGCC AACATGAGCT GACCAAGCAC CAAGTGGCCG TGAAGATCTT GAACAGACAG 180

AAGATCCGCA GTTTGGACGT GGTGGGGAAG ATCCGCAGGG AGATCCAGAA CCTCAAGCTT 240

TTCAGGCATC CTCACATAAT TAAACTGTAT CAGGTTATTA GCACCCCCAC TGATATCTTT 300

ATGGTGATGG AGTACGTCTC GGGAGGCGAG CTTTTTGACT ATATCTGCAA AAATGGAAAG 360

TTGGATGAAA AGGAGAGTCG TCGGCTGTTC CAGCAGATTA TTTCGGCAGT AGACTACTGC 420

CACAGGCACA TGGTGGTGCA CCGAGACCTC AAGCCTGAAA ATGTGCTGCT CGATGCACAC 480

ATGAATGCCA AGATTGCAGA CTTCGGATTA TCAAACATGA TGTCGGATGG AGAGTTCCTG 540

CGTACAAGCT GTGGTTCTCC AAACTATGCT GCTCCCGAGG TCATCTCAGG AAGGCTGTAT 600

GCTGGTCCAG AGGTCGATAT CTGGAGCAGT GGAGTCATCC TCTATGCCTT GTTGTGTGGG 660

ACACTTCCCT TCGATGACGA CCACGTGCCG ACCCTCTTTA AGAAGATCTG CGACGGAATC 720

TTTTTCACTC CGCAGTATCT GAACCCTTCG GTGATCAGCC TCCTTAAACA CATGCTCCAG 780

GTGGACCCCA TGAAGAGAGC CACCATCAAG GAGATCCGAG AGGATGAGTG GTTCAAGCAG 840

GGCTTACCCA AGTACTTGTT CCCGGAGGAC CCCTCCTACA GCAACAACAT GATCGACGAC 900

GAGGCCCTGA AGGAGGTGTG TGACAAGTTT GAGTGCACAG AGGAGGAGGT CCTGACCTGC 960

ATATATAGTC GCAACCACCA AGATCCGTTG GCCGTCGCCT ACCATCTCAT CATTGACAAT 1020

CGCCGCATCA TGAACGAAGC CAAGGATTTC TACCTGGCCT CCAGCCCCCC CGACTCTTTC 1080

CTGGACGACC AGCACCTGAC CGCGTCCGGC GCGTCGGTGT CCGGCATCGT CAAGGTGCAC 1140

CCCGAGCGCG TCCCCTTCCT CCTGGCGGAG ACGCCGCCCA GGCCCCGCCA CACGCTGGAC 1200

GAGTTGAACC CCCAGAAGTC CAAGCACCAG GGTGTCAGGA GGGCCAAGTG GCACCTGGGC 1260

ATCAGGAGTC AGAGTAGACC CAACGATATC ATGTCGGAGG TGTGCCGGGC CATGAAACAG 1320

CTGGATTATG AGTGGAAGGT TGTGAATCCT TATTATCTGC GCGTGAGGAG GAAGAATCCC 1380

GTGACTGGGA TGCAGACCAA GATGAGCCTC CAGCTCTACC AAGTGGACAG CAGAACCTAC 1440

CTCCTCGACT TCCGTAGCAT AGACGATGAT ATGTTGGAGA CAAAATCTGG AACTGCCACC 1500

CCTCTCCGAT CCGGGTCCGT GGGCAACTAC CGCACCACTA TTAAGAACGA TGTAGATGGG 1560

CCAGATGCTC AAGCTGCGTC TAGCACTGTG CTCCCCACCA AGGCCGCAGA AGGCTCCCTA 1620

GCTTCATCGC TGACCTCATC CATCGAATCA ACGGGAGGGG CGGACACCCC GACTGTGCCT 1680

CGACCAGGAA GCCACACCAT CGAGTTCTTT GAGATGTGTG CGAATCTTAT TAAATTACTT 1740

GCACGATAG 1749

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ +h++tk++vavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 26    YILGDTLGVGTFGKVKVGQHELTKHQVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  85

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++g+l+eke+r+lf+q++sav+Y+h++ +

Q: 86    IIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQIISAVDYCHRHMV  145

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 146   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  205

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l+++++sLl+++L+vdp k

Q: 206   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFFTPQYLNPSVISLLKHMLQVDPMK  265

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati+ei+++ew+

Q: 266   RATIKEIREDEWF  278

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGQH ELTKHQVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PTDIFMVMEY VSGGELFDYI CKNGKLDEKE SRRLFQQIIS AVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFFTPQ YLNPSVISLL KHMLQVDPMK 240

RATIKEIRED EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013