EKS-GAA-00256

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00256

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	461.0	1.4E-138	4	289	286

Status

Unreviewed

Ensembl Protein

ENSGACP00000024572

UniProt Accession

G3Q3W8;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000018588	ENSGACP00000024572	ENSGACT00000024621

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

322

Protein Sequence
(FASTA)

MERYESLGLV GEGSYGTVLK CRHRDSGRLV AIKKFMDSDD DATVKKIALR EIKLLRQLRH 60

DNLVNLLEVW KRRRRWYLVF EFVERTLLDD LEQNQGGLDL NTGRRYLYQI LRAVAFCHQQ 120

NIIHRDIKPE NILISQRGVV KMCDFGFART VAASSDGGVY TDYVATRWYR APELLVGDSK 180

YGKPVDVWAV GCLLLEMLTG QPLFPGDSDL DQIYHIVRCF GNLTAHHQEL FHRNPVFSGV 240

RLPEHSARVR LEQRFPSIAP AALDLAQSCL QMDPERRAQC SELQEHPLFT QDSFHIRYLD 300

ELNAKIQKDH KQNSTFPKIT RT 322

Nucleotide Sequence
(FASTA)

ATGGAGCGCT ACGAGTCCCT CGGGCTGGTC GGGGAGGGAA GCTACGGCAC CGTGCTCAAG 60

TGCCGCCACC GGGACTCCGG CCGCTTGGTC GCCATCAAGA AGTTCATGGA CTCGGACGAC 120

GACGCCACGG TGAAGAAGAT CGCCCTGAGG GAGATCAAGC TGCTCAGACA ACTGCGCCAC 180

GACAACCTGG TGAACCTCCT GGAGGTGTGG AAGCGCCGCC GGCGCTGGTA CCTGGTGTTC 240

GAGTTCGTGG AGCGAACCCT TCTGGACGAT CTGGAGCAGA ACCAGGGCGG CCTGGACCTG 300

AACACCGGCC GGCGATACCT CTACCAGATT CTCAGGGCGG TGGCCTTCTG CCACCAGCAG 360

AACATCATCC ATCGTGACAT CAAACCGGAG AACATACTCA TCTCCCAAAG GGGCGTGGTT 420

AAGATGTGCG ACTTCGGCTT CGCCCGGACG GTGGCGGCGT CGTCCGACGG AGGGGTCTAC 480

ACCGACTATG TGGCCACTCG CTGGTACAGG GCGCCCGAAC TCCTGGTGGG AGACTCTAAG 540

TATGGCAAGC CGGTAGACGT GTGGGCTGTC GGTTGTCTGT TGTTGGAGAT GTTAACGGGT 600

CAGCCTCTGT TCCCCGGAGA CTCCGACCTC GACCAAATCT ACCACATCGT CAGGTGCTTT 660

GGAAATCTTA CAGCTCATCA CCAGGAGTTG TTCCACAGGA ATCCCGTCTT TTCTGGAGTC 720

AGACTGCCTG AACATTCTGC CAGAGTCCGA CTGGAGCAGC GATTCCCTTC CATCGCACCG 780

GCCGCCCTGG ACCTGGCTCA GAGTTGTCTC CAGATGGATC CGGAGAGACG AGCTCAGTGT 840

TCAGAACTGC AAGAACATCC TCTGTTCACA CAAGACTCTT TCCACATAAG ATATTTGGAC 900

GAGCTGAACG CCAAGATCCA AAAAGACCAC AAACAAAACT CTACCTTCCC CAAAATAACC 960

AGAACG 966

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+vlkcr++d+g++vaikkf++s+dd +vkkialreikll+ql+h+nl

Q: 4     YESLGLVGEGSYGTVLKCRHRDSGRLVAIKKFMDSDDDATVKKIALREIKLLRQLRHDNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev++r++++ylvfe+v++t+ld+le+++ G++ ++ +++lyqil+a++fch++nii

Q: 64    VNLLEVWKRRRRWYLVFEFVERTLLDDLEQNQGGLDLNTGRRYLYQILRAVAFCHQQNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgd..vytdyvatrwyrapellvgdtkyGk  178

         hrdikpenilis++gvvk+cdfGfar++aa++d  vytdyvatrwyrapellvgd+kyGk

Q: 124   HRDIKPENILISQRGVVKMCDFGFARTVAASSDggVYTDYVATRWYRAPELLVGDSKYGK  183

         ****************************96544339************************

S: 179   svdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklp  238

         +vdvwa+Gcll e+ltG+plfpg+sd+dq+y+i++++G+l+++hq++f++n+vf+Gv+lp

Q: 184   PVDVWAVGCLLLEMLTGQPLFPGDSDLDQIYHIVRCFGNLTAHHQELFHRNPVFSGVRLP  243

         ************************************************************

S: 239   evedleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e + +  le+++p++ +++ldl+++cl++dp++r +c+el +h++f

Q: 244   EHSARVRLEQRFPSIAPAALDLAQSCLQMDPERRAQCSELQEHPLF  289

         *******************************************988

Domain Sequence
(FASTA)

YESLGLVGEG SYGTVLKCRH RDSGRLVAIK KFMDSDDDAT VKKIALREIK LLRQLRHDNL 60

VNLLEVWKRR RRWYLVFEFV ERTLLDDLEQ NQGGLDLNTG RRYLYQILRA VAFCHQQNII 120

HRDIKPENIL ISQRGVVKMC DFGFARTVAA SSDGGVYTDY VATRWYRAPE LLVGDSKYGK 180

PVDVWAVGCL LLEMLTGQPL FPGDSDLDQI YHIVRCFGNL TAHHQELFHR NPVFSGVRLP 240

EHSARVRLEQ RFPSIAPAAL DLAQSCLQMD PERRAQCSEL QEHPLF 286

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013