EKS-GAA-00077

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00077

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	387.9	3.5E-116	195	476	282

Status

Unreviewed

Ensembl Protein

ENSGACP00000025317

UniProt Accession

G3Q611;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17 (1 of 2)

Gene Synonyms/Alias

CDK17 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000019148	ENSGACP00000025317	ENSGACT00000025366

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

527

Protein Sequence
(FASTA)

MEKMKRIKKR LSLTLHSSQT IDESLSELAE QMTIDDGGTK DNEPFMRNGR PPTSHSMHSF 60

LHQYTGSFKK PPLRRPHSVI GGTLGSFMAM PRNGSRLDIV HENLKMGSDG ESDQASGTSS 120

DEVQSPTGVC LRNRLHRRIS MEDLNKRLSL PADIRIPDGY LEKLQLSSPH FDQPLSRRSR 180

RASLSEIGFG KLETYIKLDK LGEGTYATVF KGRSKLTDNL VALKEIRLEH EEGAPCTAIR 240

EVSLLKDLKH ANIVTLHDIV HTDKSLTLVF EYLDKDLKQY MDDCGNIMSM HNVKVFLFQI 300

LRGLSYCHKR KVLHRDLKPQ NLLINEKGEL KLADFGLARA KSVPTKTYSN EVVTLWYRPP 360

DVLLGSSEYS TQIDMWGVGC IFYEMAAGRP LFPGSTVEDE LHLIFRLLGT PKEENWPGIS 420

SIEEFKSHNF PKYKPQPLIN HAPRLDGEGI ELLLAFLRYE SKKRISAEEA MKHSHFRQLG 480

TRVHTLPESV SIFTLKEVQL QRDPGYRNSS YPESGNGKIN RRQSMLF 527

Nucleotide Sequence
(FASTA)

ATGGAGAAGA TGAAGAGGAT TAAGAAGCGG CTGTCGTTAA CGCTGCACTC CAGTCAGACC 60

ATCGACGAGT CGCTGTCTGA GCTGGCCGAG CAGATGACCA TCGACGACGG AGGCACAAAG 120

GACAACGAGC CCTTCATGAG GAACGGGCGC CCCCCCACCT CGCACAGCAT GCACTCCTTC 180

CTCCACCAGT ATACCGGCTC CTTTAAGAAG CCCCCGCTCC GCCGGCCGCA CAGTGTCATC 240

GGCGGCACCC TGGGGTCCTT CATGGCAATG CCTCGCAACG GCAGCCGTCT AGATATTGTG 300

CACGAGAACT TGAAGATGGG CTCTGATGGG GAGAGCGACC AGGCGTCGGG GACGTCATCA 360

GACGAGGTTC AGTCTCCGAC TGGCGTCTGC CTGAGGAACC GCCTCCACCG GAGGATTTCC 420

ATGGAGGACC TCAACAAGCG CCTGTCGCTG CCGGCCGACA TCCGAATCCC TGACGGGTAC 480

TTGGAGAAGC TGCAGCTCAG CAGCCCGCAC TTCGACCAGC CGCTCAGCCG GCGCTCACGC 540

AGAGCCTCGC TGTCGGAGAT CGGTTTTGGC AAGCTGGAGA CGTACATTAA GCTGGACAAA 600

CTGGGGGAGG GAACCTACGC CACAGTATTC AAAGGGCGCA GCAAGCTGAC GGACAACCTG 660

GTGGCACTGA AGGAGATCCG GCTTGAGCAC GAGGAGGGGG CGCCATGCAC GGCCATCAGG 720

GAAGTGTCGT TACTGAAGGA CCTCAAACAC GCCAACATCG TGACGCTTCA CGATATCGTC 780

CACACTGACA AAAGCCTCAC GCTGGTCTTC GAGTATCTGG ATAAGGACCT GAAGCAGTAC 840

ATGGATGACT GTGGAAACAT AATGAGCATG CACAATGTGA AGGTTTTCCT GTTCCAGATT 900

TTGCGAGGGC TGTCGTATTG TCATAAGAGG AAAGTTCTCC ACAGAGACCT GAAGCCCCAG 960

AACCTCCTCA TCAACGAGAA GGGGGAACTC AAACTGGCTG ATTTCGGGCT GGCGAGGGCC 1020

AAGTCCGTCC CGACCAAAAC CTACTCCAAC GAGGTGGTGA CTCTTTGGTA CCGGCCTCCT 1080

GATGTCCTGC TGGGATCCTC CGAGTACTCT ACACAGATCG ACATGTGGGG TGTTGGCTGC 1140

ATATTTTATG AGATGGCTGC AGGTCGGCCG CTGTTCCCCG GCTCCACGGT GGAAGACGAG 1200

CTGCACCTCA TCTTCAGGTT ACTGGGCACG CCAAAGGAGG AGAACTGGCC GGGGATCTCC 1260

TCCATCGAAG AGTTTAAATC CCACAACTTC CCCAAATACA AGCCGCAGCC GTTAATCAAC 1320

CACGCTCCCA GGCTGGACGG CGAAGGCATT GAGCTGCTGC TGGCTTTCCT CAGATACGAA 1380

TCCAAGAAGA GGATTTCAGC TGAAGAGGCC ATGAAACATT CCCACTTCCG GCAGCTCGGG 1440

ACGAGAGTCC ACACACTGCC TGAGAGTGTA TCGATATTCA CGTTAAAGGA AGTGCAGCTG 1500

CAGAGGGACC CTGGTTACAG GAACTCCTCT TACCCGGAGT CAGGTAACGG CAAGATCAAC 1560

AGGAGGCAGA GCATGCTCTT CTAA 1584

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++v+k+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 195   YIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  253

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+gl+y+H++k

Q: 254   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKVFLFQILRGLSYCHKRK  311

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 312   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  371

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtp+e++wp++s+++e+k ++fp

Q: 372   QIDMWGVGCIFYEMAAGRPLFPGSTVEDELHLIFRLLGTPKEENWPGISSIEEFKsHNFP  431

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ l ++ ++l+ ++++ll  +l+++ kkRisa+ea++h+ f

Q: 432   KYKPQPLINHAPRLDGEGIELLLAFLRYESKKRISAEEAMKHSHF  476

         ******************************************987

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVFKGRS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK VFLFQILRGL SYCHKRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFYE MAAGRPLFPG STVEDELHLI FRLLGTPKEE NWPGISSIEE FKSHNFPKYK 240

PQPLINHAPR LDGEGIELLL AFLRYESKKR ISAEEAMKHS HF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013