EPS-GAG-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	178.2	2.8E-52	691	935	245

Status

Unreviewed

Ensembl Protein

ENSGALP00000001287

UniProt Accession

F1NCZ7;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000000875	ENSGALP00000001287	ENSGALT00000001289

Organism

Gallus gallus

Functional Description

Protein Length

1209

Protein Sequence
(FASTA)

RRLEPTEKPL WILYDYLAGL GFDDPVRMQE EAANSDLSCM IRFYSEKPCQ VEQLDRILLS 60

GIYNVRKGKT QLHKWAERLV ILCGTCLIVS SVKDSHTGKM HILPLVGGKV EEMKRRQYTL 120

AFTSAGAQAQ TYHVSFETLA ECQRWHRQAS TVVSMRLSMV DLSCYSLEEV PEHLFYSQDI 180

TYLNLRHNFM RSSGAGSLES LCRFSQLKSL NLSHNRLGEF PVSLCEISTL TELNMSCNGL 240

YHLPSQIGKL LNLQSFWLDG NFLTSLPEEL GSLQQLSCLG LSFNNFCELP AICEKLTILD 300

KIAMAGNLLE NLDLTVLNRM NHVKSVDLRL NNLKRAAADT LEGNKSVTYM DLRDNQLTDL 360

DLSSLGSLEQ LHCERNKLKE LTLSGFSLRA LYANNNCLTS VSVYPVPGQL TCLELAHNQM 420

QCVPDWACEA KKLEILDMSY NLLVELPSRI LSSLSLRKLT VGHNNLQSLP PLLEHIPMEV 480

LDLQHNLLTK LPETLFVKAL NLRHLNASAN SLESLPSACT GEESLSMLQL LYLTNNNLTD 540

QCIPVLVGHP NLRILHLANN NLQAFPASKL SKLERLEELN LSGNKLKTIP TTVANCKLLH 600

TLIAHSNDIS IFPEILHLPH IQLVDLSCNE LNEILIPEAL PAALQELDLT GNTNLVLEHK 660

TLDIFSHITT LKIDAKPSLT TDSALTSTFW SHGVAEMAGQ RNKLCLSSLA LGSFAEGMEA 720

VYGMFDGDKN EELPRLLQCT MADVLLEEVQ QSDTMFMSNT FLVSHRKLGM AGQKLGSSAV 780

LCYIHHDMAD PASPFSLTVA NVGTCQAVLC RSGKPLLLSK VFSLEQCTEE AKRIKEQKAI 840

ITEDNKVNGV TCCTRMLGCT YLHPWILPKP HVSSIPLTVQ DELLLLGNKA LWEHLSYTEA 900

VSAVRHLHDP LAAAKKLCTL AQSYGCQDNV GAMVVYLNIS EDNCTCEMHG LSLPGPGGFS 960

STTAKTATPS SSSGIASEFG SELSASEASS EVGSTASDEH NAVGLDGSLL PRQERRCSLH 1020

PLLPSSIFQR QPSSATFSSN QSDNGLDSDD EQPVEGVMTN GSKVEVEVDI HCCKGNGLEF 1080

EPPALEYSSS APGVEDDSGL VLIIQRQNSI NSTAAHGGVK EKCELQKSPS TCCLYGKKLS 1140

NGSIVPLEES LNLIEVATEA PKKKTGYFAA PSQMEPEDQF VVPPDLEEEV KEQMKQHQEN 1200

GADQEQKEE 1209

Nucleotide Sequence
(FASTA)

AGGAGGCTGG AGCCCACCGA AAAGCCCCTT TGGATTCTGT ATGACTACTT GGCTGGGTTG 60

GGTTTTGATG ACCCTGTCAG GATGCAGGAG GAGGCAGCAA ACTCTGACCT CAGCTGTATG 120

ATTCGCTTTT ACAGTGAAAA GCCCTGTCAG GTGGAACAGT TAGATCGCAT CCTGCTCTCT 180

GGAATCTATA ATGTACGCAA AGGGAAGACT CAGTTGCACA AATGGGCAGA ACGCTTAGTA 240

ATTCTCTGTG GTACCTGTCT CATTGTGTCC TCTGTTAAAG ACAGCCACAC GGGGAAGATG 300

CACATCTTGC CTCTTGTCGG AGGGAAGGTT GAAGAAATGA AACGTCGGCA GTACACGCTT 360

GCTTTCACAT CCGCTGGAGC ACAAGCCCAA ACATACCACG TTTCCTTCGA AACGCTGGCG 420

GAGTGCCAGC GGTGGCACCG ACAGGCATCC ACGGTTGTGT CTATGCGACT TAGCATGGTT 480

GATCTTTCAT GCTACAGCCT TGAGGAAGTA CCTGAGCATC TTTTCTACAG TCAAGATATC 540

ACCTACCTCA ACCTACGACA TAATTTTATG AGATCAAGTG GAGCAGGGAG TCTTGAGTCT 600

CTTTGCAGGT TTTCTCAGTT GAAGAGCTTG AATCTGTCTC ATAACAGACT GGGGGAGTTT 660

CCTGTATCGC TGTGTGAGAT CTCTACTCTG ACTGAACTCA ATATGTCCTG TAATGGACTT 720

TATCACCTGC CAAGCCAGAT TGGCAAGCTG CTGAATCTCC AGAGCTTCTG GCTTGATGGG 780

AATTTCCTCA CATCCTTACC AGAAGAGCTT GGAAGTCTGC AGCAGCTCAG CTGCCTTGGG 840

CTTTCCTTCA ATAACTTCTG TGAGCTACCA GCAATTTGTG AGAAACTCAC CATTTTAGAC 900

AAAATAGCCA TGGCAGGGAA CTTGCTAGAG AACCTGGACC TTACAGTGCT GAACCGTATG 960

AATCACGTCA AAAGTGTGGA CTTGAGGCTG AACAACCTGA AGAGAGCAGC AGCTGACACT 1020

CTGGAGGGGA ATAAATCTGT GACTTACATG GATTTGCGAG ACAATCAGCT GACAGATCTG 1080

GATCTGAGCT CATTGGGTAG CCTGGAGCAG CTGCACTGTG AGCGGAATAA GCTGAAAGAG 1140

TTGACACTGA GTGGCTTCTC CCTTCGGGCT CTGTATGCCA ATAACAACTG TCTCACCTCT 1200

GTCAGTGTTT ATCCAGTTCC TGGTCAACTG ACATGTCTAG AACTTGCGCA CAATCAGATG 1260

CAGTGTGTCC CAGATTGGGC CTGTGAAGCA AAGAAATTGG AGATTTTGGA CATGAGCTAC 1320

AACCTCCTTG TGGAACTCCC ATCAAGGATT CTCAGCAGCT TGAGCCTTCG GAAACTGACA 1380

GTGGGGCACA ATAATCTTCA GAGCCTTCCA CCTCTTCTAG AGCACATTCC AATGGAGGTG 1440

CTGGACCTTC AGCACAACCT GTTGACTAAA CTCCCTGAGA CGCTCTTTGT CAAGGCTCTG 1500

AACCTCAGGC ACCTGAATGC ATCTGCAAAT AGCCTGGAGT CCCTGCCCTC TGCATGTACA 1560

GGGGAGGAGA GTCTGAGCAT GCTGCAGCTG CTTTACTTGA CCAATAACAA CCTCACGGAT 1620

CAGTGCATCC CTGTCTTGGT GGGACACCCG AACCTACGGA TCCTGCATCT GGCGAACAAC 1680

AACCTTCAGG CTTTCCCTGC GAGCAAACTC AGTAAGCTGG AACGCTTGGA AGAGCTGAAT 1740

CTGAGTGGCA ACAAACTGAA AACAATTCCC ACAACTGTGG CAAACTGCAA GCTACTTCAT 1800

ACACTTATTG CACACTCTAA TGACATCAGC ATCTTTCCAG AGATCCTGCA TTTACCTCAT 1860

ATACAGCTTG TGGACTTGAG TTGCAATGAA TTAAATGAAA TCCTAATCCC TGAGGCGCTG 1920

CCAGCTGCTT TGCAAGAGCT GGACCTGACT GGAAACACAA ACCTGGTGCT AGAACACAAG 1980

ACGCTGGATA TCTTCAGTCA CATTACCACG CTCAAGATTG ATGCTAAGCC CTCCCTCACA 2040

ACAGACTCGG CACTCACTTC TACTTTTTGG AGTCATGGAG TAGCTGAGAT GGCAGGACAA 2100

AGAAATAAGT TGTGTTTGTC ATCCCTGGCA CTGGGGAGCT TTGCAGAAGG GATGGAGGCT 2160

GTGTATGGCA TGTTTGATGG TGACAAGAAC GAGGAGCTGC CACGCCTGCT GCAGTGCACC 2220

ATGGCCGATG TGCTCCTGGA GGAGGTACAG CAGTCGGACA CAATGTTCAT GTCCAACACC 2280

TTCTTGGTCT CCCACAGGAA GCTGGGCATG GCTGGGCAGA AGCTGGGTTC CTCTGCTGTC 2340

CTTTGCTATA TTCATCACGA TATGGCTGAT CCAGCGAGCC CCTTTTCTCT GACTGTGGCC 2400

AATGTGGGAA CATGCCAAGC TGTTCTTTGC CGAAGTGGAA AGCCACTGCT CCTCTCCAAA 2460

GTCTTCAGTC TTGAGCAGTG TACCGAAGAG GCCAAGAGAA TCAAGGAACA AAAAGCAATT 2520

ATAACAGAGG ACAATAAGGT AAATGGTGTG ACTTGCTGTA CTCGGATGCT AGGCTGCACA 2580

TACTTGCACC CTTGGATCCT GCCCAAGCCA CATGTCAGTT CCATTCCACT GACTGTACAA 2640

GATGAGCTGC TGCTTCTAGG GAACAAAGCG TTGTGGGAAC ACCTTTCTTA CACAGAGGCC 2700

GTCTCAGCTG TGCGCCATCT ACATGACCCT CTAGCTGCTG CAAAGAAACT CTGCACATTA 2760

GCCCAAAGCT ATGGTTGCCA GGACAATGTA GGTGCAATGG TGGTGTATCT GAACATCAGT 2820

GAGGACAACT GCACATGTGA GATGCATGGC CTCTCTTTAC CAGGCCCTGG GGGATTTAGT 2880

TCCACCACTG CCAAGACAGC GACGCCTTCC TCTAGCAGTG GAATTGCTTC AGAGTTTGGT 2940

AGTGAACTGT CTGCTTCCGA GGCTAGCAGT GAGGTGGGCT CTACTGCTTC AGATGAACAC 3000

AATGCTGTTG GTCTTGATGG CAGTTTGCTA CCACGACAAG AGCGACGTTG CAGCCTACAT 3060

CCTCTGCTCC CCTCAAGCAT CTTTCAGCGC CAGCCTTCCA GTGCCACCTT CTCTAGTAAC 3120

CAGTCTGACA ATGGCTTGGA TAGTGATGAT GAACAGCCTG TGGAAGGTGT GATGACAAAT 3180

GGCAGTAAAG TGGAGGTAGA GGTGGATATC CACTGCTGTA AAGGGAATGG TCTGGAATTT 3240

GAACCTCCTG CTTTAGAGTA CAGCTCCTCT GCTCCAGGAG TAGAGGATGA CTCTGGACTT 3300

GTCCTCATCA TTCAGAGACA GAACAGCATA AACAGCACAG CTGCACATGG AGGGGTCAAG 3360

GAAAAGTGTG AACTGCAGAA ATCTCCTTCC ACATGCTGTC TCTATGGAAA GAAGCTTTCC 3420

AATGGCTCCA TTGTGCCCTT GGAGGAGAGC CTTAACCTCA TTGAAGTAGC CACAGAGGCT 3480

CCCAAGAAGA AGACAGGTTA TTTTGCTGCT CCATCCCAGA TGGAGCCAGA GGATCAATTT 3540

GTGGTGCCAC CTGATCTGGA GGAGGAAGTG AAGGAGCAAA TGAAGCAGCA CCAGGAGAAT 3600

GGAGCAGATC AGGAGCAGAA AGAAGAG 3627

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++gv+++ g+rn+++ ++ + ++f++  e     a++g++DG++++e  + +++++ ++l

Q: 691   SHGVAEMAGQRNKLCLSSLALGSFAEGME-----AVYGMFDGDKNEELPRLLQCTMADVL  745

         689*****************999999866.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++      +  + ++ ++Fl  +++l       ++ +k Gs+av+++i ++

Q: 746   LEEVQ------QSDTMFMSNTFLVSHRKL------GMAGQKLGSSAVLCYIHHDmadpas  793

         ***88......556678************......89***************999*****

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk++ ls+ ++ ++  +E +Ri+e+++ +++++  +v+Gv+

Q: 794   pfSLTVANVGTCQAVLCRSGKPLLLSKVFSLEQCtEEAKRIKEQKAIITEDN--KVNGVT  851

         ******************************986449*********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+v+s++lt +de l L+ + lw+++s  eavs+vr+ ++

Q: 852   CCTRMLGCTYLHPWILPKPHVSSIPLTVQDELLLLGNKALWEHLSYTEAVSAVRHLHD--  909

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 910   --PLAAAKKLCTLAQSYGCQDNVGAMVV  935

         ..************************97

Domain Sequence
(FASTA)

SHGVAEMAGQ RNKLCLSSLA LGSFAEGMEA VYGMFDGDKN EELPRLLQCT MADVLLEEVQ 60

QSDTMFMSNT FLVSHRKLGM AGQKLGSSAV LCYIHHDMAD PASPFSLTVA NVGTCQAVLC 120

RSGKPLLLSK VFSLEQCTEE AKRIKEQKAI ITEDNKVNGV TCCTRMLGCT YLHPWILPKP 180

HVSSIPLTVQ DELLLLGNKA LWEHLSYTEA VSAVRHLHDP LAAAKKLCTL AQSYGCQDNV 240

GAMVV 245

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>