EKS-GAG-00073

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00073

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	446.3	7.9E-134	2313	2639	327

Status

Unreviewed

Ensembl Protein

ENSGALP00000004185

UniProt Accession

F1NGW1;

Protein Name

Protein Synonyms/Alias

Gene Name

ATR

Gene Synonyms/Alias

ATR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000002663	ENSGALP00000004185	ENSGALT00000004194

Organism

Gallus gallus

Functional Description

Protein Length

2664

Protein Sequence
(FASTA)

AMAEQGLEMA SMIPALRELA SATPEEYNIV VQKPRQILCQ FIDRILTDVD VVALELIKKS 60

DSQPSSVMLL DFIQHIMKSS PLMFVNVDGS QEETECNCIE FSNWIITRLL RIAATPSCIT 120

LHKNISDVIC SLLFLFKMKS CSIFETLTRD LLQLFQDLIF LHERDTQKQL WGDVLVWPVT 180

VKRFSSNASD NVAYLRLAPL HLMGMPNVEC LEVILLSILM DIAADVFFVR QDTVLWGIGC 240

SLLEYGCPKV KALAMNFLIK LIHLGGPPEQ LASVFFTVFF GILHSALEMD TEELELCGEP 300

FLQLVRTLMP FEADSYKNIE PVYLNMLLEK LCALFEGDMF MHLRSEKLKA AFCHILQYFL 360

ELVPPGYESA LQVRKVHVNT ICKVFVSVLG TQEEQEYLVS PLYTVLKTQT EEIYQELHQS 420

QLDTSDTSGW SSSSDEVPQK RRRLSLPAKH PKKSPAPDLL SPVNMKLKST LWNAITKKAA 480

SLISVLEKES LTANVLQTAE GIAIILQLAA LCVVHCSPPT NSSSTDHKVT HLCNTDTCKN 540

TPCSLDSVEN IQFTWISSDF ITRVVKACGN LLEAATKMVN LEQVIDRTVK IFDALLYAQI 600

KIPLNHQILD NMCGLLSLPW ICSHPDVSPF KTSAFGTDPL VLSQKTAQSF SPRTQSRCVF 660

LLSLFPRNIH LDWRKSIYYW ALQSPHEVIR ATCVKGFSFL LHPPSVQSFS TIPKALLNQI 720

QDESDLVKEA CAAIVGKLSC CLSGTFCVQP PSADSAIKHA ACDILCNGLT ATSAHEKTCS 780

VQACVFKPFL ILLENKVSSS VKLAFIENIP HLCKHLDFNS DESSVKVLIG SLLNLMEDPD 840

KDVRVAFSDC IKSILESLDS EEGFIKELFV SRMKEAYTHA KISRNNELKD TLILTTGDIG 900

RASKGDLVPF ALLHLLHCLL SKSASVAGAA YTEIRSLAAA KSIKLQAFFS QYKKPICQFL 960

VESLHSSQMA VLSAPCQGNE LHKQEAAHQR EMALDMLSEI ANVFDFPDLN RFLSRTLQVL 1020

LPDLAAKASP AASTLIRTIA KQLNVNRREI LINNFKYIFS HLVCSCSKDE LERALHYLKN 1080

ETEIELGSLL RQDYQGLHNE LLLRIGEHYQ QVFNGLSILA SFASHDDPYQ GPREITSSEQ 1140

MADYLQPKLL GILAFFNMQL LSSSVGIEDK KMALNSLMSL MKLMGPKHIS SVRVKMMTTL 1200

RTALRYKDDF PELCCRAWDC FVRSLDHSYL GSLLSHVIVA LLPLIHIQPK ETTAVFHFLI 1260

VENRDTVRDF LHEIYFLPDL PELKEIQVVL QEYRKESSKS TDLQTTLQLS MRAIQHENVD 1320

VRIHALTSLK ETLYRNQEKL VKYVTDSETV EPVISQLVTV LLIGCQDANS HARLLCGECL 1380

GELGAIDPGR LDFSTSETQG KDFTFVAGVE DPNFAYGLLM ELTRAFLAYA DNVRAQDSAA 1440

YAIQELLSIY DCRETNSDCP GSRLWRRFPE HVQEILEPHL NTRYKSYQKA IDWSKMKKPI 1500

YLSKLGDNFA EWSATWAGYL ITKVRHDLAR KVFDCCSIMM KNDYKVTIYL LPHILVYVLL 1560

GCSQEDQQEV YMEIMAVLKH DDQCSRRLQD SASDLSQLST QTVFSMLDHL TQWARHKFQM 1620

LIAEKNTSKS SKDRSDLKTS SEDYGEYQNV TRFLDLIPQD TLAVASFRSK AYTRAVMHFE 1680

SFITEKKQNI QEHLGFLQKL YAAMHEPDGV AGVSAIRKAE PSLKEQILEH ESIGLLRDAT 1740

ACYDRAIQLE PDQIIHYHGV VKSMLGLGQL STVITQVNGV LANRSEWISE LNTYRVEAAW 1800

KLSQWDLLEN YLASGKKDVK SSAWSVRLGH LLLSAKKKNE VAFYETLKVV RAEQIVPLSA 1860

ASFERGSYQR GYEHIIRLHM LCELEHSIGP MFQQLDGEHG RDSLNWCARI EMTQNSYRAK 1920

EPILALRRAL LSLSKSQDYS ELVGQCWLQS ARVARKAGHH QTAYNALLNA GESTLSELYI 1980

ERAKWLWSKG EVHQALIVLQ KGVELCFPEN KAPCDTKNQL IHGRATLLVG RFMEETANFE 2040

SNAVMKKYKD VTLLLPEWED GHFYLAKYYD KLMPMVTDNK MEKQGDLIRY IVHHFGRSLQ 2100

YGNQFIYQSM PRMLSLWLDF GAKAYECDKA SRSERVQMKN DLAKINKVIT EHTNQLAPYQ 2160

FLTAFSQLIS RICHSHDEVF AVLMVIVAKV FLAYPQQAMW MMTAVSKSSY PMRVNRCKEI 2220

LNKAINMKES LGKFIGDATR LTDKLLELCN KPVDGNSSAL SMNIHFRTLK RLVEEHTFSQ 2280

ILIPLQSVMI PTLPSIPGTH ANHDPFPGCW AYIAGFDDTV EILASLQKPK KITLKGSDGK 2340

SYIMMCKPKD DLRKDCRLME FNSLINKCLR KDAESRRREL HIRTYAVIPL NDECGIIEWV 2400

NNTAGLRNIL IKLYKEKGIY MTGKELRQHM LPKSAPLPEK LKMFKEVLLP RHPPVFHEWF 2460

LRTFPDPTSW YNSRSAYCRS VAVMSMVGYI LGLGDRHGEN ILFDSLTGEC VHVDFNCLFN 2520

KGETFEVPEI VPFRLTHNMV NGMGPMGTEG LFRRACEVTM RLMRDQREPL MSVLKTFLHD 2580

PLVEWSKPVK GNTKAQVNET GEVVNEKAKT HVLDIEQRLQ GVIKTRNRIK GLPLSIEGHV 2640

HYLIQEASDD NLLCQMYMGW APYM 2664

Nucleotide Sequence
(FASTA)

GCTATGGCCG AGCAGGGCCT GGAGATGGCC TCTATGATCC CCGCGCTGCG GGAGCTCGCT 60

AGTGCTACTC CAGAAGAATA CAATATAGTT GTTCAGAAAC CAAGACAAAT ACTCTGCCAG 120

TTCATTGACA GAATTCTTAC TGATGTAGAT GTGGTTGCTT TGGAACTCAT TAAGAAATCA 180

GATTCACAGC CAAGTTCTGT AATGCTACTA GATTTTATTC AACATATCAT GAAATCTTCT 240

CCCCTTATGT TTGTAAATGT CGATGGAAGT CAAGAGGAAA CAGAGTGCAA TTGCATTGAA 300

TTTAGTAATT GGATCATAAC AAGACTTCTC CGAATTGCTG CAACTCCAAG CTGTATCACA 360

TTGCACAAGA ACATCTCTGA TGTCATTTGC TCTTTACTTT TCCTGTTTAA AATGAAAAGT 420

TGCTCCATCT TTGAAACGCT AACAAGAGAC TTGCTACAGC TTTTCCAAGA TTTAATCTTC 480

CTGCATGAAC GAGACACACA AAAGCAGCTC TGGGGAGATG TGCTGGTATG GCCAGTGACA 540

GTGAAGAGAT TTTCAAGTAA TGCAAGTGAC AATGTGGCAT ATTTAAGATT AGCACCATTG 600

CACCTGATGG GTATGCCCAA TGTAGAATGT CTGGAAGTTA TATTGTTGTC TATCCTGATG 660

GATATTGCTG CAGATGTATT TTTTGTAAGA CAGGATACTG TTCTCTGGGG AATAGGATGC 720

TCCCTGTTGG AGTATGGTTG TCCAAAGGTT AAAGCTTTAG CAATGAACTT TTTAATAAAA 780

TTAATTCATT TGGGAGGACC TCCGGAACAG CTGGCCAGTG TTTTCTTCAC AGTCTTTTTC 840

GGAATTCTAC ATTCAGCACT TGAAATGGAT ACTGAAGAAC TGGAACTCTG CGGAGAACCG 900

TTCTTACAAT TGGTGAGAAC ATTAATGCCT TTTGAAGCAG ACTCTTACAA AAACATTGAA 960

CCTGTCTATT TGAATATGCT ACTGGAGAAG CTTTGTGCAC TGTTTGAAGG AGATATGTTT 1020

ATGCATCTTC GTTCCGAAAA GCTGAAAGCT GCTTTTTGCC ATATACTGCA ATATTTTCTG 1080

GAGTTGGTTC CGCCTGGCTA TGAATCTGCC TTACAAGTAA GAAAAGTCCA TGTCAATACC 1140

ATATGCAAAG TTTTTGTGAG CGTGCTTGGA ACTCAGGAAG AACAAGAGTA TCTGGTGAGT 1200

CCACTTTACA CAGTATTAAA AACACAAACA GAAGAAATCT ATCAGGAGCT TCATCAGAGC 1260

CAGTTAGATA CTTCTGATAC CAGTGGGTGG AGCAGCAGCA GTGATGAAGT TCCACAGAAA 1320

AGACGGCGAC TGAGCCTACC AGCAAAGCAT CCAAAGAAAT CACCTGCACC AGATCTACTT 1380

AGCCCGGTAA ACATGAAATT GAAGAGTACA CTGTGGAATG CCATCACAAA GAAAGCTGCA 1440

TCTTTAATAT CTGTCCTCGA GAAAGAAAGT CTGACGGCGA ATGTTCTTCA GACTGCAGAA 1500

GGAATTGCCA TAATTCTGCA ACTAGCCGCG TTGTGTGTAG TTCATTGCTC TCCCCCAACA 1560

AATTCTAGCA GTACAGATCA TAAAGTAACT CATCTGTGTA ACACTGACAC ATGCAAGAAT 1620

ACTCCATGCT CCTTGGATTC TGTGGAGAAT ATACAATTCA CATGGATTTC CTCTGACTTT 1680

ATCACAAGAG TAGTGAAAGC GTGTGGGAAC CTGTTAGAGG CTGCTACAAA GATGGTTAAC 1740

CTAGAACAAG TGATTGACAG AACAGTGAAA ATCTTTGATG CGTTGCTGTA TGCACAAATA 1800

AAAATTCCAC TGAATCATCA GATTCTTGAT AATATGTGTG GATTGCTGTC TCTACCCTGG 1860

ATTTGCAGCC ATCCTGATGT TTCTCCTTTT AAAACATCTG CTTTTGGGAC CGATCCTCTA 1920

GTTTTAAGTC AAAAAACTGC TCAGAGTTTC TCACCTCGAA CTCAGTCACG TTGTGTGTTC 1980

CTTCTGTCTC TCTTCCCGAG AAACATTCAT CTGGATTGGC GAAAATCCAT TTACTATTGG 2040

GCACTACAAA GTCCCCATGA AGTAATTCGG GCTACATGTG TTAAAGGATT CTCTTTCCTG 2100

CTTCATCCAC CAAGTGTGCA GTCCTTCAGT ACGATTCCAA AGGCTCTTTT AAACCAAATC 2160

CAAGATGAGT CTGATCTAGT CAAGGAGGCT TGTGCTGCTA TTGTTGGGAA ATTATCTTGC 2220

TGTCTTTCTG GTACATTCTG TGTACAGCCT CCTTCAGCAG ACTCTGCTAT AAAGCATGCT 2280

GCCTGTGATA TTTTATGTAA CGGCCTTACT GCGACTTCTG CTCATGAAAA AACTTGCTCT 2340

GTGCAAGCCT GTGTTTTTAA GCCATTTCTT ATTCTTCTTG AGAACAAAGT GTCCAGTTCA 2400

GTAAAACTAG CATTTATAGA AAACATACCT CACCTTTGCA AACATCTGGA TTTTAACAGT 2460

GATGAGTCAA GTGTGAAGGT TCTCATTGGG TCTTTATTAA ATCTAATGGA AGATCCAGAC 2520

AAAGATGTAC GCGTGGCTTT CAGTGACTGC ATAAAGAGCA TATTAGAATC CTTAGACTCT 2580

GAAGAAGGAT TCATAAAAGA GCTCTTTGTT TCAAGAATGA AAGAAGCGTA TACACATGCC 2640

AAAATATCAA GAAATAATGA GCTTAAGGAT ACCTTGATTC TCACAACAGG AGATATTGGA 2700

AGGGCATCGA AAGGAGATTT GGTACCGTTT GCCCTCTTGC ATTTGTTGCA TTGTTTGCTG 2760

TCCAAGTCAG CTTCTGTGGC TGGAGCAGCA TACACTGAAA TTCGGTCCCT GGCAGCAGCT 2820

AAGTCCATAA AACTACAAGC TTTTTTCAGT CAGTACAAGA AACCCATCTG TCAGTTTCTA 2880

GTGGAATCCC TGCACTCCAG CCAGATGGCA GTATTGAGTG CTCCATGCCA GGGTAATGAG 2940

CTGCACAAAC AAGAAGCTGC TCACCAGAGA GAAATGGCTC TGGACATGTT GTCTGAGATT 3000

GCTAATGTGT TTGACTTTCC AGATCTAAAT CGCTTTTTGT CACGGACCCT GCAAGTTTTG 3060

CTGCCTGACC TTGCAGCCAA GGCCAGTCCT GCAGCCTCCA CCCTTATTCG AACCATAGCA 3120

AAACAGCTGA ACGTAAACCG AAGAGAGATT TTAATCAACA ACTTCAAGTA CATCTTCTCT 3180

CATTTGGTCT GTTCCTGTTC TAAGGATGAG CTTGAGCGGG CACTTCATTA CCTCAAGAAT 3240

GAGACTGAGA TCGAACTGGG CAGCTTGTTG AGACAGGACT ACCAAGGACT GCATAATGAA 3300

TTACTGCTAC GTATAGGAGA ACACTATCAG CAAGTATTCA ATGGTTTGTC AATATTGGCT 3360

TCATTTGCAT CTCATGATGA TCCCTATCAG GGACCTAGGG AAATAACGTC ATCTGAGCAA 3420

ATGGCTGATT ATCTGCAGCC TAAATTGCTT GGTATCTTGG CCTTTTTTAA CATGCAGTTA 3480

TTGAGTTCCA GTGTTGGCAT TGAGGATAAA AAAATGGCCC TGAACAGTCT TATGTCTTTA 3540

ATGAAGCTTA TGGGTCCCAA ACACATCAGT TCAGTACGAG TGAAGATGAT GACTACGCTG 3600

AGAACAGCTC TAAGATACAA GGATGACTTT CCAGAGCTGT GTTGCAGAGC CTGGGACTGT 3660

TTTGTTCGAA GTCTGGACCA TTCATACCTT GGTTCCTTGC TTAGTCATGT GATAGTAGCG 3720

TTGTTGCCTC TTATACATAT CCAGCCAAAG GAAACTACAG CAGTGTTTCA CTTTCTCATA 3780

GTTGAGAACA GGGATACAGT ACGAGACTTC TTACATGAAA TATATTTTCT GCCTGACCTT 3840

CCAGAACTAA AAGAAATTCA AGTTGTCCTT CAGGAGTATC GAAAGGAATC CTCCAAGAGC 3900

ACTGACTTGC AGACGACGTT GCAACTGTCC ATGAGAGCTA TTCAGCATGA GAATGTGGAT 3960

GTTCGTATCC ATGCACTTAC CAGCCTGAAA GAAACATTAT ATAGAAATCA GGAAAAATTG 4020

GTGAAGTATG TAACAGACAG TGAAACTGTG GAGCCAGTCA TCTCTCAGTT GGTAACTGTA 4080

CTTCTAATTG GCTGTCAGGA TGCAAATTCT CATGCCCGAC TGCTCTGTGG GGAATGTTTA 4140

GGTGAACTGG GAGCCATAGA CCCCGGCAGG CTGGATTTTT CAACAAGTGA AACTCAAGGA 4200

AAAGATTTTA CATTTGTGGC TGGTGTGGAG GATCCAAATT TTGCATATGG ATTATTGATG 4260

GAACTGACTA GAGCATTTCT TGCTTACGCT GACAATGTTC GTGCTCAGGA TTCGGCAGCA 4320

TATGCCATTC AGGAGTTATT GTCTATCTAT GACTGTAGAG AGACAAACAG TGACTGCCCA 4380

GGCTCCAGGC TGTGGAGGAG ATTTCCTGAG CACGTGCAGG AAATCTTGGA ACCTCACTTA 4440

AATACACGGT ACAAGAGTTA TCAAAAGGCT ATAGATTGGT CAAAGATGAA GAAGCCTATT 4500

TACCTAAGCA AATTAGGTGA CAATTTTGCA GAATGGTCAG CAACTTGGGC AGGTTACCTT 4560

ATAACAAAGG TACGACATGA TCTTGCCAGA AAAGTTTTTG ATTGCTGCAG TATTATGATG 4620

AAGAATGACT ATAAAGTTAC AATTTATCTG CTACCACACA TCCTTGTCTA TGTTTTGTTG 4680

GGATGCAGTC AGGAGGATCA ACAAGAGGTT TACATGGAGA TTATGGCTGT CCTGAAGCAT 4740

GATGACCAGT GTAGTAGGAG ACTTCAAGAC AGTGCATCTG ATCTAAGTCA GCTGAGCACA 4800

CAGACAGTGT TCTCCATGCT TGATCATCTA ACTCAGTGGG CTAGACATAA GTTTCAGATG 4860

CTCATTGCTG AGAAAAATAC TAGCAAGTCT AGCAAAGACA GAAGTGATCT AAAAACTTCA 4920

AGTGAGGACT ATGGAGAATA TCAGAATGTG ACACGCTTTT TAGACCTGAT ACCTCAAGAT 4980

ACGCTCGCTG TGGCTTCTTT TCGCTCTAAG GCTTACACAA GGGCTGTGAT GCATTTTGAG 5040

TCATTCATCA CAGAGAAGAA ACAAAATATT CAGGAGCATC TTGGATTTCT GCAGAAGTTG 5100

TATGCTGCTA TGCACGAGCC AGATGGAGTA GCTGGAGTGA GTGCAATCCG GAAAGCAGAA 5160

CCATCTCTCA AAGAACAAAT CCTCGAACAT GAAAGTATTG GCTTGTTAAG AGATGCCACA 5220

GCCTGTTACG ATAGGGCTAT CCAACTAGAA CCTGATCAGA TTATTCATTA CCATGGTGTA 5280

GTGAAGTCGA TGTTAGGCCT TGGTCAGTTA TCTACTGTAA TTACTCAAGT GAATGGAGTA 5340

CTTGCAAACA GGTCTGAATG GATTTCTGAA TTGAACACAT ATAGAGTTGA AGCAGCCTGG 5400

AAACTGTCAC AGTGGGATTT ACTGGAGAAT TATTTGGCTT CAGGTAAGAA AGATGTCAAG 5460

TCCTCTGCTT GGAGTGTCAG ATTAGGACAC TTATTATTAT CAGCCAAGAA GAAGAATGAA 5520

GTTGCCTTTT ATGAAACACT CAAGGTTGTT CGAGCAGAAC AGATTGTGCC CCTTTCAGCA 5580

GCGAGCTTTG AAAGAGGATC CTATCAGCGA GGATATGAAC ACATTATCAG GTTGCATATG 5640

CTCTGTGAGT TGGAACATAG TATTGGACCA ATGTTTCAGC AACTAGATGG TGAACATGGC 5700

AGAGATTCCC TGAATTGGTG TGCTCGTATT GAAATGACCC AGAATTCTTA CAGAGCAAAA 5760

GAACCTATTT TAGCACTAAG AAGGGCTTTG CTTAGTCTTA GTAAAAGCCA GGATTACAGT 5820

GAGCTTGTTG GTCAGTGCTG GCTCCAGAGT GCTAGAGTTG CAAGAAAAGC TGGTCATCAT 5880

CAGACTGCAT ATAATGCTCT TCTGAATGCT GGGGAATCTA CACTCTCAGA ACTTTATATA 5940

GAAAGAGCAA AGTGGCTCTG GTCCAAGGGT GAGGTTCACC AAGCACTTAT TGTTCTCCAG 6000

AAGGGAGTGG AGTTATGTTT CCCTGAGAAT AAAGCACCAT GCGATACCAA AAATCAGCTC 6060

ATCCATGGTC GGGCAACGCT GCTGGTTGGT AGATTTATGG AGGAAACTGC TAACTTTGAA 6120

AGTAATGCAG TTATGAAAAA GTATAAGGAT GTCACACTTT TGTTGCCAGA ATGGGAAGAT 6180

GGACACTTCT ATCTTGCTAA GTACTATGAC AAATTAATGC CAATGGTAAC TGACAATAAG 6240

ATGGAAAAAC AAGGAGATCT GATTAGATAC ATAGTTCATC ATTTTGGAAG GTCTCTACAG 6300

TATGGAAACC AGTTCATCTA TCAGTCAATG CCAAGAATGC TATCTTTATG GCTGGACTTT 6360

GGAGCAAAAG CATACGAGTG TGATAAAGCA AGTCGTTCGG AACGCGTTCA AATGAAAAAT 6420

GATTTGGCTA AAATAAATAA AGTGATTACA GAGCACACAA ATCAGCTAGC GCCTTATCAG 6480

TTTCTGACAG CTTTTTCTCA GTTAATCTCC CGAATCTGCC ATTCTCATGA TGAAGTTTTT 6540

GCTGTTCTGA TGGTGATTGT TGCTAAGGTG TTTTTAGCCT ACCCACAGCA AGCAATGTGG 6600

ATGATGACTG CTGTGTCCAA GTCCTCATAC CCTATGCGTG TCAATAGATG CAAGGAAATC 6660

CTAAATAAAG CTATCAACAT GAAGGAGTCC TTAGGAAAAT TTATTGGAGA TGCAACACGC 6720

CTTACGGATA AGCTGTTAGA ACTATGCAAC AAACCGGTTG ATGGAAACAG CTCAGCATTA 6780

AGCATGAATA TTCATTTCAG AACACTTAAG AGATTGGTAG AAGAGCACAC ATTCAGTCAA 6840

ATTCTCATTC CATTACAATC TGTAATGATA CCAACTCTTC CTTCAATTCC GGGTACGCAT 6900

GCTAACCATG ACCCGTTTCC TGGATGCTGG GCCTACATTG CAGGCTTTGA TGATACGGTA 6960

GAAATTCTTG CTTCCCTTCA AAAGCCAAAA AAGATCACTT TGAAAGGTTC AGATGGGAAA 7020

TCTTATATTA TGATGTGTAA ACCTAAAGAT GATCTAAGAA AGGACTGTCG GCTCATGGAA 7080

TTCAACTCTC TTATTAATAA GTGCTTAAGA AAAGATGCAG AGTCGCGTCG TCGAGAGCTC 7140

CATATACGGA CCTATGCAGT TATTCCGTTA AATGATGAAT GTGGCATAAT TGAATGGGTG 7200

AACAATACTG CTGGTTTAAG AAATATCCTG ATAAAACTTT ATAAGGAGAA GGGTATCTAT 7260

ATGACTGGAA AGGAACTACG TCAGCATATG CTTCCAAAGT CAGCACCTTT GCCTGAAAAG 7320

CTGAAAATGT TCAAAGAAGT CCTTCTGCCT CGTCATCCTC CTGTTTTTCA TGAATGGTTT 7380

CTTAGAACGT TTCCTGATCC TACTTCATGG TATAACAGCA GGTCTGCCTA CTGCCGTTCT 7440

GTTGCAGTCA TGTCAATGGT AGGTTACATA CTTGGTCTAG GAGACCGGCA TGGTGAAAAC 7500

ATCCTGTTCG ATTCTTTGAC CGGTGAATGC GTGCATGTGG ATTTCAACTG CCTTTTCAAT 7560

AAGGGAGAAA CTTTTGAAGT CCCGGAAATA GTTCCTTTTC GTCTCACACA TAACATGGTT 7620

AATGGAATGG GTCCAATGGG AACAGAAGGT CTCTTCCGAA GAGCTTGTGA AGTCACAATG 7680

AGGCTTATGC GTGATCAAAG GGAGCCTTTA ATGAGTGTCT TAAAGACTTT TCTTCATGAT 7740

CCTCTTGTGG AGTGGAGTAA GCCTGTTAAA GGGAATACAA AGGCACAGGT GAATGAAACT 7800

GGAGAAGTTG TCAATGAAAA GGCCAAAACC CATGTCCTTG ATATAGAACA ACGGCTACAA 7860

GGTGTTATTA AGACTAGAAA CAGAATAAAA GGATTACCCT TATCTATTGA AGGGCATGTT 7920

CATTACCTCA TTCAAGAAGC AAGTGATGAC AATCTCCTCT GCCAAATGTA TATGGGCTGG 7980

GCTCCATATA TGTAA 7995

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         iagfd++veilas+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N++L+kd

Q: 2313  IAGFDDTVEILASLQKPKKITLKGSDGKSYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD  2372

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +e++rr+L+irty+V+pl++++g+iewv+nt++L+++l kl+++k++++          +

Q: 2373  AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRNILIKLYKEKGIYMT--------GK  2424

         *************************************************5........99

S: 121   stvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAv  180

         + +q + pk++ l ++l++fkevl +++p+ ++++++l++fp+p++w+++r+ay+rs+Av

Q: 2425  ELRQHMLPKSAPLPEKLKMFKEVLLPRHPP-VFHEWFLRTFPDPTSWYNSRSAYCRSVAV  2483

         *****************************8.*****************************

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn+

Q: 2484  MSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNG  2542

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce ++r++r+++e l+++L++fl+dplv+w+k     +k++ +et+e

Q: 2543  MGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKpvkgnTKAQVNETGE  2602

         ************************************************99999*******

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

         +++ekak++ l+i+++l++v k++n+++ ++l+++++

Q: 2603  VVNEKAKTHVLDIEQRLQGVIKTRNRIKGLPLSIEGH  2639

         ********************************99987

Domain Sequence
(FASTA)

IAGFDDTVEI LASLQKPKKI TLKGSDGKSY IMMCKPKDDL RKDCRLMEFN SLINKCLRKD 60

AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRNILIK LYKEKGIYMT GKELRQHMLP 120

KSAPLPEKLK MFKEVLLPRH PPVFHEWFLR TFPDPTSWYN SRSAYCRSVA VMSMVGYILG 180

LGDRHGENIL FDSLTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG MGPMGTEGLF 240

RRACEVTMRL MRDQREPLMS VLKTFLHDPL VEWSKPVKGN TKAQVNETGE VVNEKAKTHV 300

LDIEQRLQGV IKTRNRIKGL PLSIEGH 327

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0001741	; C:XY body
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0071480	; P:cellular response to gamma radiation
GO:0034644	; P:cellular response to UV
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0008156	; P:negative regulation of DNA replication
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0043517	; P:positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777	; P:protein autophosphorylation
GO:0043393	; P:regulation of protein binding
GO:0090399	; P:replicative senescence

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50077	; HEAT_REPEAT; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013