EKS-GAG-00180

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00180

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF3	496.4	4.8E-149	355	685	331

Status

Unreviewed

Ensembl Protein

ENSGALP00000004348

UniProt Accession

F1N891;

Protein Name

Protein Synonyms/Alias

Gene Name

PEAK1

Gene Synonyms/Alias

PEAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000002759	ENSGALP00000004348	ENSGALT00000004357

Organism

Gallus gallus

Functional Description

Protein Length

768

Protein Sequence
(FASTA)

EKPSIVFMYR CEPTQTEPKA DHQYKSGVES AIADVLAKDK GETQEKSPES PEQKITSHPS 60

PPQILKKIPS QVPDDTTLED LSPRVPRAVF VKQDNGGSAS VIPVSAVRAP QGEEDKGEAP 120

HPSDLNPCSA TYSNLGQSRA AMIPPKQPRQ PKGALDDAIA FGGIVDQETM NSLQPTPPPL 180

PKKTILRANT EPSPRDLQKQ ALENNLCIVA NPTYDIDTNW EASSACSSVS LELKALDNES 240

GDSLDRPTEK LRTTTSATNS VSSLTTISIK DRCSNSMESL TGRRLSQSKQ SRGVQKPQRQ 300

ALYRGIENRE EVVGKIRSLH TDSLKKLALK CEDLFMAGQK DQLRFGVDSW SDFRLTSDKP 360

CCEAGDAVYY PASYAKDPLN HYAVKICKSK AKESQQYYHS LSIRQSLAIN FNIQQDCGHF 420

LAEVPVRLLP WEDADAPEVE EEQEEEQEPE QKNGGTPSST EASQKDSSSN QGTISKPRSR 480

VVVITREVPY LTVADFVRES APRHAKSPDL YERQVCLLLL QLCLGLEHLK PYHITHCDLR 540

LENLLLVHSR PGGGPLSSES VEPGPSTACP ARLIVSNFSQ AKQKSHMVDP EVLRDQSRLA 600

PEIITATQYK KCDEFQTGIL IYEMLHLPNP FDENPELKEK EYTHADLPKI PCRSLYSQGL 660

QQLASCLLNP NPSERILISE AKGILQCLLW GPREDLFHAL RTSSNPARKD AVLQNWLDIK 720

RTLLMIKFAE KSFDRDCGVI LEDWLCCQYL AFATVDSLHR IVRIMQRH 768

Nucleotide Sequence
(FASTA)

GAGAAGCCGT CAATTGTTTT CATGTACAGG TGTGAACCAA CGCAAACCGA ACCGAAGGCT 60

GACCATCAGT ACAAGAGCGG AGTGGAGTCT GCTATCGCAG ATGTACTTGC AAAAGACAAA 120

GGGGAAACAC AGGAGAAGTC TCCGGAGAGC CCTGAGCAGA AAATAACGAG CCATCCATCA 180

CCACCTCAGA TCCTGAAGAA AATCCCCAGT CAAGTGCCCG ATGATACCAC GCTGGAGGAT 240

TTGTCCCCCC GTGTCCCAAG AGCCGTGTTT GTGAAGCAGG ACAATGGTGG CAGCGCCTCG 300

GTCATACCCG TGTCAGCTGT CCGTGCCCCT CAGGGGGAGG AAGACAAAGG AGAAGCTCCA 360

CATCCTTCTG ATTTGAATCC TTGCAGTGCC ACGTACAGCA ATTTAGGACA GTCCAGAGCA 420

GCCATGATAC CTCCGAAACA GCCGAGGCAG CCGAAGGGAG CTTTGGACGA TGCCATTGCC 480

TTTGGAGGGA TAGTGGACCA GGAGACAATG AACAGCTTAC AGCCAACACC ACCTCCGCTG 540

CCGAAAAAGA CAATTCTGAG AGCTAACACA GAGCCGAGCC CCAGAGACCT CCAGAAGCAA 600

GCTCTTGAGA ACAACCTGTG CATCGTGGCC AATCCCACCT ATGACATTGA CACCAACTGG 660

GAAGCCAGCA GCGCCTGCTC CTCGGTCAGC TTGGAGCTCA AGGCACTGGA CAACGAGTCG 720

GGAGATTCCT TGGACAGGCC TACGGAGAAG TTAAGGACAA CCACCTCAGC AACTAACAGT 780

GTTTCCAGCC TAACCACTAT CAGTATTAAG GACCGCTGCT CCAATAGCAT GGAGTCTCTG 840

ACGGGGAGAC GTCTCTCGCA GTCTAAGCAG AGCAGAGGTG TCCAGAAGCC ACAGAGGCAA 900

GCACTTTATC GAGGAATTGA GAATCGAGAA GAAGTGGTAG GTAAAATCCG AAGCCTTCAC 960

ACTGATTCAC TGAAGAAGCT GGCACTTAAA TGTGAAGACT TGTTCATGGC TGGACAAAAA 1020

GACCAGCTGC GATTCGGAGT GGACAGCTGG TCGGATTTCA GGCTCACCAG CGACAAGCCG 1080

TGCTGTGAGG CAGGTGATGC AGTTTACTAC CCGGCTTCTT ATGCAAAAGA TCCTCTCAAC 1140

CATTATGCAG TCAAGATTTG TAAGAGCAAA GCTAAGGAGT CCCAGCAGTA TTATCACAGC 1200

CTGTCTATCC GGCAGAGTCT GGCCATCAAC TTTAACATCC AGCAGGACTG TGGCCATTTC 1260

CTTGCTGAAG TGCCAGTTCG CCTCCTCCCA TGGGAGGATG CCGATGCACC AGAGGTGGAA 1320

GAAGAGCAAG AAGAAGAGCA AGAACCTGAG CAAAAGAACG GAGGCACCCC TTCCAGTACA 1380

GAGGCTTCGC AGAAGGACAG CTCAAGTAAC CAGGGGACCA TCAGCAAGCC ACGCAGCCGT 1440

GTTGTAGTCA TCACACGAGA GGTGCCATAC TTAACAGTGG CTGATTTTGT GCGAGAGTCC 1500

GCTCCTCGCC ATGCCAAAAG CCCGGATTTA TATGAGAGGC AGGTCTGTCT TCTCCTTTTA 1560

CAGCTGTGTT TGGGCCTGGA GCACCTGAAG CCCTACCACA TCACACACTG TGATCTGCGG 1620

CTAGAGAACC TGCTGCTGGT TCATTCCAGA CCAGGAGGCG GCCCTCTGAG CTCTGAGTCC 1680

GTGGAGCCCG GCCCCAGCAC TGCTTGCCCA GCCAGGTTAA TAGTGAGCAA TTTCTCACAG 1740

GCCAAGCAGA AGAGTCATAT GGTAGATCCT GAGGTCCTAC GGGATCAGTC CCGCCTGGCT 1800

CCAGAAATCA TCACTGCAAC GCAGTACAAA AAGTGCGATG AATTTCAGAC TGGCATCCTT 1860

ATCTACGAAA TGCTGCACTT ACCCAACCCC TTTGATGAGA ATCCAGAGCT GAAGGAGAAG 1920

GAGTACACTC ATGCTGATCT CCCCAAGATC CCTTGCCGCT CCCTCTACTC CCAAGGGCTT 1980

CAACAACTTG CCAGCTGCTT GCTGAATCCC AACCCCTCTG AGAGGATCCT GATATCAGAA 2040

GCCAAGGGAA TCCTTCAGTG CTTGCTTTGG GGTCCACGCG AGGACTTGTT CCATGCTCTA 2100

AGAACATCTT CCAACCCAGC CCGGAAAGAT GCTGTACTTC AGAACTGGCT GGACATCAAA 2160

AGGACGCTGC TGATGATAAA GTTTGCCGAG AAGTCCTTTG ACAGGGACTG CGGAGTGATT 2220

CTGGAAGACT GGCTTTGTTG TCAATATCTG GCTTTTGCGA CTGTAGACTC GCTTCATCGC 2280

ATCGTGAGAA TCATGCAGCG GCAC 2304

Domain Profile

S: 1     ltsdkpcceagdavyytasyakdplsnyavkickskekksqsy.....vrqslpvhfniq  55

         ltsdkpcceagdavyy asyakdpl+ yavkicksk+k+sq+y     +rqsl++ fniq

Q: 355   LTSDKPCCEAGDAVYYPASYAKDPLNHYAVKICKSKAKESQQYyhslsIRQSLAINFNIQ  414

         79**********************************************************

S: 56    qdcGhflaevpsrlla..dpdapekd...........pkpasetepsake..........  92

         qdcGhflaevp rll+  d dape +                       +

Q: 415   QDCGHFLAEVPVRLLPweDADAPEVEeeqeeeqepeqK-----------Nggtpssteas  463

         ****************9999999998555666665550...........44444444445

S: 93    ..............rdhvvvitrevphltvadfvrdslashraepelyerrvcllllqlc  138

                       r+ vvvitrevp+ltvadfvr+s+ +h ++p+lyer+vcllllqlc

Q: 464   qkdsssnqgtiskpRSRVVVITREVPYLTVADFVRESAPRHAKSPDLYERQVCLLLLQLC  523

         55577788899999**********************************************

S: 139   sGlehlkeygvihrdlrlenlllvhlqpqagaaqaaapaepaptsaapsaapaattasqe  198

          Glehlk+y+++h+dlrlenlllvh +p +g+  +    ep p++a+p

Q: 524   LGLEHLKPYHITHCDLRLENLLLVHSRPGGGPLSS-ESVEPGPSTACP------------  570

         ****************************6666555.5577********............

S: 199   gprekqltrlivsnflkakqksgglvdlqikkdqarlapeivsasqykkfdefqtGiliy  258

                +rlivsnf++akqks ++vd+++++dq+rlapei++a+qykk+defqtGiliy

Q: 571   -------ARLIVSNFSQAKQKS-HMVDPEVLRDQSRLAPEIITATQYKKCDEFQTGILIY  622

         .......8**************.*************************************

S: 259   ellhlpnpfevraelkereyrredlprlpllslysrGlqqlasllleadpikriliseak  318

         e+lhlpnpf++++elke+ey+++dlp++p +slys+Glqqlas+ll+++p++riliseak

Q: 623   EMLHLPNPFDENPELKEKEYTHADLPKIPCRSLYSQGLQQLASCLLNPNPSERILISEAK  682

         ************************************************************

S: 319   rvl  321

++l

Q: 683   GIL  685

*98

Domain Sequence
(FASTA)

LTSDKPCCEA GDAVYYPASY AKDPLNHYAV KICKSKAKES QQYYHSLSIR QSLAINFNIQ 60

QDCGHFLAEV PVRLLPWEDA DAPEVEEEQE EEQEPEQKNG GTPSSTEASQ KDSSSNQGTI 120

SKPRSRVVVI TREVPYLTVA DFVRESAPRH AKSPDLYERQ VCLLLLQLCL GLEHLKPYHI 180

THCDLRLENL LLVHSRPGGG PLSSESVEPG PSTACPARLI VSNFSQAKQK SHMVDPEVLR 240

DQSRLAPEII TATQYKKCDE FQTGILIYEM LHLPNPFDEN PELKEKEYTH ADLPKIPCRS 300

LYSQGLQQLA SCLLNPNPSE RILISEAKGI L 331

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005925	; C:focal adhesion
GO:0005524	; F:ATP binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0016477	; P:cell migration
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013