EPS-GAG-00029

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00029

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	193.0	8.5E-57	159	373	215

Status

Unreviewed

Ensembl Protein

ENSGALP00000008491

UniProt Accession

F1P1V0;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000005304	ENSGALP00000008491	ENSGALT00000008505

Organism

Gallus gallus

Functional Description

Protein Length

604

Protein Sequence
(FASTA)

GERRAAPRGA SRPMEGPYSL GVSVYSDQGG RKYMEDVTQI VVEPDGTGGA VCAQLPLEAV 60

GCPMAASVMN TGSSRKFDRT SRAPSGSSQC ALVEWLCCTC TSSTPVVFSC PRHLSSVRCH 120

WGSVSPHSSG GAGAVRKECR VLLVGEGSCY LWVWEQGAEW PKTMTGLPST SGTTASVVII 180

RGSKMYVAHV GDSGVVLGVQ DDPKDDFVRA VEVTQDHKPE LPKERERIEG LGGSVINKSG 240

VNRVVWKRPR LTHNGPVRRS TVIDQIPFLA VARALGDLWS YDFYSGEFVV SPEPDTSVHT 300

IDPQKHKYII LGSDGLWNMI PPQDAISMCQ DHEEKKYFMG EHRQSCAKML VNRALGRWRQ 360

RMLRADNTSA IVICISPLQD SKNNLENEEE LYLNLADSPC YSSPDTNIMT PSRCCTPPVK 420

LLEDDPWPRL NASEPVPSLM HSNVISEKYA ELPNEIAKSN LPSSGATLKD SGPQDEKCSK 480

ALALRIQESY SNGLSVSLSP SNSTISGTDQ KGLKVSPNGQ TKAQDAERTP TANFKRTLEE 540

SNSGPAVKKP RRGLSRSMGV QAEGISTTPQ RKNSNKLAMR RSLRGQKKLS SSLFHPPRKA 600

VCVC 604

Nucleotide Sequence
(FASTA)

GGGGAGCGGC GGGCAGCGCC GCGCGGAGCC TCCCGCCCCA TGGAGGGGCC GTACTCGCTG 60

GGGGTGAGCG TGTACTCCGA CCAGGGCGGC AGGAAATACA TGGAGGACGT GACCCAGATC 120

GTGGTGGAGC CTGATGGCAC TGGAGGAGCA GTCTGTGCTC AGCTGCCCCT GGAAGCAGTG 180

GGTTGCCCCA TGGCTGCATC CGTGATGAAC ACTGGCAGCA GTAGAAAGTT TGACAGAACT 240

TCCAGAGCCC CATCTGGGAG CAGCCAATGT GCTTTAGTAG AGTGGCTGTG CTGTACATGT 300

ACTTCCTCCA CACCTGTGGT GTTTTCTTGC CCCAGGCATC TGAGCAGTGT TCGGTGTCAC 360

TGGGGCTCAG TGAGTCCCCA TTCTTCTGGC GGAGCGGGTG CAGTGAGGAA GGAGTGCAGG 420

GTGCTGCTGG TGGGCGAGGG CAGCTGTTAT CTGTGGGTAT GGGAGCAGGG AGCAGAGTGG 480

CCGAAGACCA TGACTGGTCT CCCGAGCACG TCGGGAACCA CTGCCAGCGT GGTCATCATC 540

CGAGGCTCAA AGATGTATGT TGCTCATGTG GGCGACTCCG GGGTGGTGCT GGGAGTTCAG 600

GATGACCCCA AGGATGATTT TGTGAGAGCT GTGGAGGTGA CGCAGGACCA CAAGCCTGAG 660

CTTCCCAAAG AAAGGGAGAG GATTGAAGGC CTTGGGGGCA GCGTCATCAA CAAGTCTGGT 720

GTGAATCGTG TCGTCTGGAA GAGACCTCGC CTGACTCACA ACGGCCCTGT GCGCCGCAGC 780

ACTGTCATCG ACCAGATTCC CTTCCTGGCC GTGGCCAGAG CGCTTGGTGA TCTGTGGAGC 840

TACGACTTCT ACAGTGGAGA ATTTGTTGTG TCTCCAGAAC CTGACACTAG TGTGCACACC 900

ATTGATCCCC AGAAGCACAA ATACATTATC CTTGGCAGTG ATGGACTGTG GAACATGATC 960

CCACCTCAAG ATGCTATCTC CATGTGCCAG GATCACGAGG AGAAAAAGTA CTTCATGGGT 1020

GAGCACCGCC AGTCCTGTGC CAAAATGCTG GTGAACAGAG CACTAGGCCG GTGGAGGCAG 1080

CGCATGCTTC GTGCAGATAA CACTAGTGCC ATCGTGATCT GCATCTCACC GCTGCAGGAT 1140

AGCAAAAACA ATTTGGAAAA TGAAGAAGAA CTGTATCTCA ATTTGGCAGA CAGTCCCTGC 1200

TATAGCAGCC CTGATACAAA CATCATGACG CCCTCCCGCT GCTGTACCCC GCCTGTCAAG 1260

CTTTTAGAGG ATGATCCGTG GCCACGACTG AATGCTTCTG AGCCTGTTCC TTCCCTCATG 1320

CATAGCAACG TGATCTCAGA AAAATATGCC GAGCTGCCAA ACGAGATTGC CAAAAGCAAT 1380

TTACCTTCAT CAGGAGCAAC CCTGAAGGAT TCAGGTCCAC AGGACGAGAA GTGCAGCAAA 1440

GCGTTGGCTT TGAGGATACA GGAATCCTAC AGTAACGGTT TGTCAGTCAG TCTGTCCCCA 1500

TCCAACTCTA CAATTTCAGG CACGGACCAA AAAGGCTTAA AAGTGTCTCC TAACGGCCAA 1560

ACAAAAGCCC AGGATGCGGA GAGGACACCC ACAGCAAACT TTAAAAGGAC ATTAGAAGAG 1620

TCCAATTCTG GCCCAGCTGT GAAGAAGCCG AGACGCGGCC TGAGCCGAAG CATGGGTGTC 1680

CAAGCAGAGG GCATATCCAC AACGCCGCAG CGCAAGAACT CAAACAAGCT GGCCATGCGG 1740

CGCAGCCTGC GCGGCCAGAA GAAGCTCAGC AGCTCACTCT TCCACCCGCC CAGGAAAGCA 1800

GTCTGTGTTT GCTGA 1815

Domain Profile

S: 91    kvleeksldidksGstavvalikdsklyvanvGdSravLcrngk.......avelssdHk  143

         +++++++  +++sG+ta+v++i++sk+yva+vGdS++vL+ +++       ave+++dHk

Q: 159   EWPKTMTGLPSTSGTTASVVIIRGSKMYVAHVGDSGVVLGVQDDpkddfvrAVEVTQDHK  218

         799**************************************77656999999********

S: 144   psredEleRieeaggsvilkdga.Rv.....................lGvLavsRalGdl  181

         p+ ++E+eRie  ggsvi+k+g+ Rv                     +++Lav+RalGdl

Q: 219   PELPKERERIEGLGGSVINKSGVnRVvwkrprlthngpvrrstvidqIPFLAVARALGDL  278

         ************************************************************

S: 182   ylk......pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvle....  230

         +++      ++v+peP++++h+++++++ ++iL+sDGlw+++++++a+s+++d++e

Q: 279   WSYdfysgeFVVSPEPDTSVHTIDPQKHkYIILGSDGLWNMIPPQDAISMCQDHEEkkyf  338

         ************************************************************

S: 231   kkeaeqeaakkLvklalargsk.....dnvsaivv  260

         ++e+ q++ak+Lv++al r+++     dn+saiv+

Q: 339   MGEHRQSCAKMLVNRALGRWRQrmlraDNTSAIVI  373

         *********************************97

Domain Sequence
(FASTA)

EWPKTMTGLP STSGTTASVV IIRGSKMYVA HVGDSGVVLG VQDDPKDDFV RAVEVTQDHK 60

PELPKERERI EGLGGSVINK SGVNRVVWKR PRLTHNGPVR RSTVIDQIPF LAVARALGDL 120

WSYDFYSGEF VVSPEPDTSV HTIDPQKHKY IILGSDGLWN MIPPQDAISM CQDHEEKKYF 180

MGEHRQSCAK MLVNRALGRW RQRMLRADNT SAIVI 215

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0000086	; P:G2/M transition of mitotic cell cycle
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013