EPS-GAG-00020

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00020

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	101.5	3.8E-29	11	145	135

Status

Unreviewed

Ensembl Protein

ENSGALP00000011462

UniProt Accession

F1N842;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP12

Gene Synonyms/Alias

DUSP12;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000007084	ENSGALP00000011462	ENSGALT00000011476

Organism

Gallus gallus

Functional Description

Protein Length

316

Protein Sequence
(FASTA)

SRSRCGGMVP VLPGLYVGGA ESCSSSKALA AAGVMAVLTV DAEEPPPLPG VRTLYIRALD 60

EPGADLLSRL DECAAFIGAA RAGGGAVLVR CQAGVSRSVA VVTAYLMKTQ GLGWEEAYAA 120

VRAAKPDAEV NPGFQRQLKL YEAMGCAVDS SSALYKQHRL QVLTERFSEL QDLPQEVFAV 180

DPTIACQTPN TEVLYRCRKC RRALFRSSSI LSHVEGSGPT AFAHKRITES THLRGSGPDK 240

CTSYFIEPVQ WMEPALLGVT EGQLLCPKCT SKLGSFSWWG EQCSCGHWVT PAFQIHKSRV 300

DEARTLSVGN FHTAKT 316

Nucleotide Sequence
(FASTA)

AGCCGGAGCC GGTGCGGCGG GATGGTGCCG GTGCTGCCGG GGCTTTACGT GGGCGGCGCG 60

GAGTCGTGCT CGTCCTCGAA GGCGCTGGCG GCGGCGGGGG TGATGGCGGT GCTGACGGTG 120

GACGCGGAGG AGCCGCCTCC GTTGCCGGGG GTGCGGACGT TGTACATCCG GGCGCTGGAC 180

GAGCCCGGTG CCGACCTGCT GAGCCGCCTG GACGAGTGCG CTGCCTTCAT CGGCGCGGCG 240

CGGGCGGGCG GCGGGGCCGT CCTCGTGCGG TGCCAGGCCG GAGTGAGCCG CAGCGTGGCC 300

GTGGTGACCG CGTACCTGAT GAAGACCCAG GGGCTCGGCT GGGAGGAGGC GTACGCCGCC 360

GTCAGGGCCG CCAAACCCGA TGCCGAGGTG AACCCGGGCT TCCAGAGGCA GCTGAAGCTA 420

TACGAGGCCA TGGGCTGTGC CGTGGATAGC AGCAGTGCCC TGTACAAGCA GCATCGCCTG 480

CAGGTGCTCA CGGAGAGGTT CTCCGAACTT CAAGACTTAC CCCAAGAAGT CTTTGCTGTC 540

GATCCAACCA TTGCATGTCA GACTCCAAAC ACAGAAGTTC TCTATAGATG CAGGAAATGC 600

AGGCGCGCTC TGTTCCGCAG TTCCAGCATT TTGTCCCACG TGGAAGGAAG TGGACCAACA 660

GCCTTTGCTC ACAAGAGAAT AACAGAGTCT ACGCATCTTC GTGGCAGTGG CCCTGATAAG 720

TGCACCTCTT ACTTCATTGA GCCCGTGCAG TGGATGGAGC CAGCACTGCT AGGAGTAACG 780

GAAGGACAGC TTTTGTGTCC CAAATGCACG TCTAAGCTGG GTTCCTTTAG CTGGTGGGGT 840

GAGCAGTGTT CTTGCGGCCA CTGGGTGACC CCTGCCTTCC AGATACACAA AAGTCGAGTG 900

GATGAAGCGA GAACTCTGTC AGTTGGTAAC TTCCACACTG CCAAAACCTG A 951

Domain Profile

S: 5     ilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdDsd  64

         +lpgly+g+++     + L ++g+  v+++ ++              g++ + i + D++

Q: 11    VLPGLYVGGAESCSSSKALAAAGVMAVLTVDAEEPP--P------LPGVRTLYIRALDEP  62

         89***************************9998877..2......35788899*******

S: 65    vtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavk  124

           dll+ +de+a+fi  a+  gg+vlv C+aGvsRS+++v+aYLmk++gl +++A+ av+

Q: 63    GADLLSRLDECAAFIGAARAGGGAVLVRCQAGVSRSVAVVTAYLMKTQGLGWEEAYAAVR  122

         ************************************************************

S: 125   rkrpsiepnegfleQLlelekkl  147

         + +p +e n gf +QL ++e ++

Q: 123   AAKPDAEVNPGFQRQLKLYEAMG  145

         ********************997

Domain Sequence
(FASTA)

VLPGLYVGGA ESCSSSKALA AAGVMAVLTV DAEEPPPLPG VRTLYIRALD EPGADLLSRL 60

DECAAFIGAA RAGGGAVLVR CQAGVSRSVA VVTAYLMKTQ GLGWEEAYAA VRAAKPDAEV 120

NPGFQRQLKL YEAMG 135

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR016278	; DUSP12.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

Created Date

20-Feb-2013