EPS-GAG-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	229.4	6.6E-68	93	349	257

Status

Unreviewed

Ensembl Protein

ENSGALP00000015507

UniProt Accession

E1BTL4;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1L

Gene Synonyms/Alias

PPM1L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000009537	ENSGALP00000015507	ENSGALT00000015523

Organism

Gallus gallus

Functional Description

Protein Length

360

Protein Sequence
(FASTA)

MIEDTMTLLS LLGRIMRYFL LRPETLFLLC ISLALWSYFF HTDEVKTIVK SSRDAVKMVK 60

GKVAEIMQND RLGGLDVLDA EFSKTWEFKS HNVAVYSIQG RRDHMEDRFE VITDLVNKTH 120

PSIFGIFDGH GGESAAEYVK SRLPEVLKQH LQDYEKDKEN SVMSYQTILE QQILSIDREM 180

LEKLTVSYDE AGTTCLIALL SDKELTVANV GDSRGVLCDK DGNAIPLSHD HKPYQLKERK 240

RIKRAGGFIS FNGSWRVQGI LAMSRSLGDY PLKNLNVVIP DPDILTFDLD KLQPEFMILA 300

SDGLWDAFSN EEAVRFIKER LDEPHFGAKS IVLQSFYRGC PDNITVMVVK FRNSSKTDEQ 360

Nucleotide Sequence
(FASTA)

ATGATAGAGG ATACAATGAC TTTGCTGTCT CTGCTGGGTC GGATCATGCG TTACTTCTTG 60

CTCAGACCAG AGACCCTGTT CTTGCTGTGC ATCAGCCTGG CCCTGTGGAG TTATTTCTTT 120

CACACGGATG AGGTGAAAAC CATTGTTAAG TCCAGCAGGG ATGCAGTGAA GATGGTGAAG 180

GGCAAGGTGG CCGAGATCAT GCAGAATGAC AGGCTCGGGG GGCTGGACGT GCTGGATGCC 240

GAGTTCTCCA AGACCTGGGA GTTCAAGAGC CACAATGTGG CTGTCTATTC CATCCAAGGC 300

CGGAGGGATC ACATGGAGGA CAGGTTCGAA GTAATCACCG ACCTGGTGAA CAAGACTCAT 360

CCCTCCATCT TCGGGATATT TGATGGGCAC GGAGGAGAGT CAGCAGCAGA GTATGTGAAG 420

TCCCGCCTGC CTGAAGTCCT GAAACAACAT CTTCAGGACT ATGAGAAGGA CAAGGAGAAC 480

AGTGTGATGT CTTATCAGAC CATCCTGGAA CAGCAGATTT TATCAATTGA TCGAGAAATG 540

CTGGAAAAAT TGACTGTATC CTATGATGAA GCAGGTACAA CTTGTTTGAT TGCGTTGCTG 600

TCAGATAAAG AGCTCACTGT GGCCAATGTT GGTGATTCGC GAGGCGTGCT GTGTGACAAG 660

GACGGGAATG CCATCCCCCT GTCACACGAC CACAAGCCCT ACCAGCTGAA AGAGAGGAAG 720

AGGATTAAAA GAGCTGGTGG ATTTATCAGC TTTAATGGCT CCTGGCGTGT TCAGGGCATC 780

CTGGCCATGT CCCGCTCGTT AGGAGATTAC CCTCTGAAGA ACCTGAATGT TGTCATTCCT 840

GACCCTGATA TTCTCACCTT TGACCTGGAC AAACTGCAGC CAGAGTTCAT GATCCTGGCA 900

TCTGATGGTC TGTGGGATGC CTTCAGCAAC GAGGAAGCCG TCCGATTCAT CAAGGAACGC 960

TTGGATGAGC CACACTTTGG AGCAAAGAGT ATAGTTCTAC AGTCGTTTTA CAGAGGATGT 1020

CCCGATAATA TAACAGTGAT GGTGGTGAAG TTCAGGAATA GCAGCAAGAC AGACGAACAG 1080

TAA 1083

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         v v+s++grr++med++++ +++++++      ++fg++DGhgg+++a++++++l e+l+

Q: 93    VAVYSIQGRRDHMEDRFEVITDLVNKTHP----SIFGIFDGHGGESAAEYVKSRLPEVLK  148

         6789*******************998775....69*************************

S: 63    eele....sseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdskly  118

         + l+    ++e++    +++l++  ls+d+e+  le+ + + d+ G+t+++al++d++l+

Q: 149   QHLQdyekDKENSVMSYQTILEQQILSIDREM--LEKLTVSYDEAGTTCLIALLSDKELT  206

         ****765444445555569*************..999999********************

S: 119   vanvGdSravLcr.ngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsR  176

         vanvGdSr vLc+ +g+a++ls dHkp + +E++Ri++agg +  + g  Rv+G La+sR

Q: 207   VANVGDSRGVLCDkDGNAIPLSHDHKPYQLKERKRIKRAGGFISFN-GSwRVQGILAMSR  265

         *************566************************999977.667**********

S: 177   alGdlylk..pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekke  233

         +lGd+ lk   +v+p+P++  ++l++ +  f+iLasDGlwd +sneeav++++++l+

Q: 266   SLGDYPLKnlNVVIPDPDILTFDLDKLQPeFMILASDGLWDAFSNEEAVRFIKERLD---  322

         ********8889************765544***************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

         ++   ak++v ++  rg+ dn++++vv

Q: 323   EPHFGAKSIVLQSFYRGCPDNITVMVV  349

         999********************9997

Domain Sequence
(FASTA)

VAVYSIQGRR DHMEDRFEVI TDLVNKTHPS IFGIFDGHGG ESAAEYVKSR LPEVLKQHLQ 60

DYEKDKENSV MSYQTILEQQ ILSIDREMLE KLTVSYDEAG TTCLIALLSD KELTVANVGD 120

SRGVLCDKDG NAIPLSHDHK PYQLKERKRI KRAGGFISFN GSWRVQGILA MSRSLGDYPL 180

KNLNVVIPDP DILTFDLDKL QPEFMILASD GLWDAFSNEE AVRFIKERLD EPHFGAKSIV 240

LQSFYRGCPD NITVMVV 257

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0000165	; P:MAPK cascade
GO:0006470	; P:protein dephosphorylation
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

gga:429162

;

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013