EKS-GAG-00135

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00135

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	578.6	2.1E-174	396	655	260

Status

Unreviewed

Ensembl Protein

ENSGALP00000015569

UniProt Accession

F1P396;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK1

Gene Synonyms/Alias

TLK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000009569	ENSGALP00000015569	ENSGALT00000015585

Organism

Gallus gallus

Functional Description

Protein Length

655

Protein Sequence
(FASTA)

ELLEARFTGV VSGSTGSTGS CSVGAKASTN NESSNHSFGS LGSLSDKESE TPEKKQSEPS 60

RGRKRKADTQ SESSQGKSIG GRGHKISDYF EYQGGNGSSP VRGVPPAIRS PQNSHSAPSS 120

AFQVRQNSPS PTSLAFGDHP TTQPKQLSFK ITQTDLTMLK LAALESNKNQ DLEKKEGRID 180

DLLRANCDLR RQIDEQQKLL EKYKERLNKC ISMSKKLLIE KSTQEKLASR EKSMQDRLRL 240

GHFTTVRHGA SFTEQWTDGF AFQNLVKQQE WVNQQREDIE RQRKLLAKRK PPTTNNSQAP 300

SANSEPKQRK NKAVNGAEND PFVRPNLPQL LTLAEYHEQE EIFKLRLGHL KKEEAEIQAE 360

LERLERVRNL HIRELKRINN EDNSQFKDHP TLNERYLLLH LLGRGGFSEV YKAFDLYEQR 420

YAAVKIHQLN KSWRDEKKEN YHKHACREYR IHKELDHPRI VKLYDYFSLD TDTFCTVLEY 480

CEGNDLDFYL KQHKLMSEKE ARSIVMQIVN ALRYLNEIKP PIIHYDLKPG NILLVDGTAC 540

GEIKITDFGL SKIMDDDSYG VDGMDLTSQG AGTYWYLPPE CFVVGKEPPK ISNKVDVWSV 600

GVIFFQCLYG RKPFGHNQSQ QDILQENTIL KATEVQFPVK PVVSNEAKAF IRRCL 655

Nucleotide Sequence
(FASTA)

GAATTGTTAG AGGCAAGATT CACAGGAGTA GTAAGTGGCA GCACTGGGAG TACTGGAAGT 60

TGCAGCGTTG GAGCTAAAGC CTCAACAAAT AATGAAAGTT CGAACCACAG TTTTGGAAGC 120

TTGGGATCTT TAAGTGATAA AGAATCAGAG ACTCCAGAGA AGAAACAGTC AGAACCTTCC 180

AGAGGAAGAA AAAGAAAAGC AGACACTCAG AGTGAAAGCA GCCAAGGAAA GAGTATTGGG 240

GGACGTGGCC ACAAGATTAG TGACTATTTT GAGTACCAAG GTGGAAACGG CTCTAGTCCA 300

GTTCGAGGTG TACCTCCTGC AATCCGATCT CCTCAGAATT CACATTCCGC CCCTTCTTCT 360

GCATTCCAGG TTCGACAGAA TAGTCCTTCT CCTACTTCAT TAGCTTTTGG GGACCACCCT 420

ACCACGCAAC CAAAGCAGTT ATCTTTTAAA ATTACTCAGA CTGATCTCAC AATGCTGAAA 480

TTAGCTGCAC TAGAAAGTAA TAAAAATCAA GACTTGGAAA AGAAAGAAGG TCGTATAGAT 540

GACTTACTCA GGGCTAACTG TGATCTTAGA AGACAAATAG ATGAACAACA AAAGCTACTT 600

GAAAAATATA AGGAAAGGTT AAACAAATGT ATTTCAATGA GCAAGAAGCT TCTAATTGAA 660

AAGAGCACAC AAGAAAAGCT GGCAAGCAGA GAGAAGAGCA TGCAAGACAG ATTACGCCTG 720

GGGCATTTTA CAACAGTTCG TCATGGTGCT TCATTTACTG AACAGTGGAC AGATGGCTTT 780

GCATTTCAGA ATCTTGTAAA GCAGCAAGAA TGGGTGAATC AACAAAGGGA AGACATTGAA 840

AGGCAAAGAA AGCTCCTGGC CAAGAGAAAG CCACCAACTA CAAATAATTC TCAGGCACCA 900

TCTGCCAATT CTGAACCCAA GCAGAGGAAA AATAAAGCTG TGAATGGGGC AGAAAACGAT 960

CCCTTTGTTA GACCCAATTT GCCACAGCTT TTGACTCTAG CAGAGTATCA CGAACAGGAA 1020

GAAATTTTCA AACTTCGATT AGGACATCTC AAGAAGGAGG AAGCTGAAAT ACAAGCAGAA 1080

CTTGAACGTT TGGAAAGAGT TAGGAATCTT CACATCAGAG AACTGAAAAG AATAAATAAT 1140

GAAGATAATT CACAGTTTAA AGATCACCCC ACATTGAATG AACGGTATTT GTTACTCCAC 1200

TTACTTGGCC GAGGTGGCTT CAGTGAAGTA TACAAGGCTT TTGATCTTTA TGAACAAAGA 1260

TATGCTGCTG TGAAGATTCA CCAGCTTAAC AAAAGCTGGA GGGATGAAAA GAAAGAAAAC 1320

TACCACAAAC ATGCCTGCAG AGAGTATAGA ATACACAAAG AACTGGATCA CCCCCGGATA 1380

GTTAAATTAT ATGACTACTT CTCCTTGGAT ACAGATACGT TTTGCACGGT GTTAGAATAC 1440

TGTGAAGGCA ATGACTTGGA TTTCTATCTC AAGCAACATA AATTGATGTC AGAGAAGGAA 1500

GCTAGGTCCA TTGTAATGCA AATAGTAAAT GCACTACGGT ATCTCAATGA GATCAAGCCC 1560

CCTATTATAC ACTATGATCT TAAACCAGGT AATATTCTTC TTGTAGATGG AACAGCATGT 1620

GGAGAAATAA AAATTACTGA TTTTGGCTTG TCCAAAATAA TGGATGATGA TAGCTATGGT 1680

GTGGATGGAA TGGATTTAAC TTCACAGGGA GCAGGAACTT ACTGGTACTT GCCTCCAGAG 1740

TGTTTTGTAG TTGGCAAAGA GCCACCAAAG ATTTCTAATA AGGTTGATGT ATGGTCAGTT 1800

GGAGTAATCT TTTTCCAGTG TCTTTATGGT AGAAAGCCAT TTGGCCACAA TCAATCACAG 1860

CAAGATATCT TACAAGAAAA TACAATATTA AAAGCCACAG AAGTCCAGTT CCCTGTTAAG 1920

CCTGTTGTTA GCAATGAAGC CAAGGCCTTT ATCAGACGCT GTTTAG 1966

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqry+avkihqlnk+w+dekkeny+kha+reyrihkel

Q: 396   YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKEL  455

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtd+fctvley+egndldfylkqhkl+sekearsi+mqiv+al+yl

Q: 456   DHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYL  515

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimdddsy++d g++ltsqgagty

Q: 516   NEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD-GMDLTSQGAGTY  574

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvif+qclyg+kpfghnqsqqdil+entilkate

Q: 575   WYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATE  634

         ************************************************************

S: 241   vqfpskpvvsseakafirrcl  261

         vqfp+kpvvs+eakafirrcl

Q: 635   VQFPVKPVVSNEAKAFIRRCL  655

         ********************8

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LYEQRYAAVK IHQLNKSWRD EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDTFC TVLEYCEGND LDFYLKQHKL MSEKEARSIV MQIVNALRYL 120

NEIKPPIIHY DLKPGNILLV DGTACGEIKI TDFGLSKIMD DDSYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGVIFF QCLYGRKPFG HNQSQQDILQ ENTILKATEV 240

QFPVKPVVSN EAKAFIRRCL 260

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006886	; P:intracellular protein transport
GO:0035556	; P:intracellular signal transduction
GO:0001672	; P:regulation of chromatin assembly or disassembly

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013