EPS-GAG-00023

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00023

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	288.4	6.4E-86	6	275	270

Status

Unreviewed

Ensembl Protein

ENSGALP00000031284

UniProt Accession

F1NM90;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1B

Gene Synonyms/Alias

PPM1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000009970	ENSGALP00000031284	ENSGALT00000031920

Organism

Gallus gallus

Functional Description

Protein Length

422

Protein Sequence
(FASTA)

AGNGLRYGLC SMQGWRVEME DAHTAVVGIP HGLDWSFFAV YDGHAGSRVA NYCSTHLLEH 60

ITNNEDFRAA EKPGSALEPS VENVKSGIRT GFLKIDEYMR NFSDLRNGMD RSGSTAVGVM 120

ISPEHVYFIN CGDSRAVLYR NGQVCFSTQD HKPCNPREKE RIQNAGGSVM IQRVNGSLAV 180

SRALGDYDYK CVDGKGPTEQ LVSPEPEVCE ILRAEEDEFI ILACDGIWDV MSNEELCEFV 240

KSRLEVSDDL EKVCNWVVDT CLHKGSRDNM SIVLVCLSNA PKVSDEAVKK DAELDKHLES 300

RVEEIMEKSG EEGMPDLAHV IRILSAENIP NLPPGGGLAG KRNIIEAVYS RLNPHRENEG 360

DPGEAEESGT QGKLVEALRQ MRINHRGNYR HLLEEMLTSY RLAKMQGEEC TAESAAASAS 420

DN 422

Nucleotide Sequence
(FASTA)

GCAGGGAATG GCTTGCGTTA CGGCCTCTGC AGTATGCAGG GATGGAGAGT GGAAATGGAA 60

GATGCTCACA CAGCTGTTGT AGGTATTCCC CATGGCTTAG ACTGGTCCTT TTTTGCTGTC 120

TATGATGGTC ATGCAGGATC TCGTGTTGCA AATTATTGCT CCACACACTT ACTAGAACAC 180

ATCACTAACA ATGAAGACTT TAGGGCAGCA GAAAAACCTG GATCTGCTCT TGAACCTTCA 240

GTGGAAAATG TCAAGAGTGG AATCAGAACT GGCTTTTTGA AAATTGATGA GTATATGCGC 300

AATTTCTCAG ACCTCAGAAA TGGGATGGAC AGAAGTGGCT CAACAGCAGT GGGAGTTATG 360

ATTTCACCTG AGCATGTGTA CTTTATCAAT TGCGGTGATT CACGTGCTGT TCTCTATAGG 420

AATGGACAAG TCTGTTTTTC AACACAGGAT CACAAACCTT GCAACCCAAG GGAGAAAGAG 480

CGAATCCAGA ACGCAGGAGG CAGTGTAATG ATTCAGCGTG TCAATGGTTC ATTGGCAGTT 540

TCTCGAGCTC TGGGGGACTA TGACTACAAA TGTGTTGATG GTAAAGGCCC TACAGAACAA 600

CTTGTTTCTC CAGAGCCTGA GGTTTGTGAA ATTTTAAGGG CAGAAGAAGA TGAGTTTATC 660

ATCTTGGCTT GTGATGGAAT CTGGGATGTA ATGAGCAACG AAGAGCTCTG TGAATTTGTT 720

AAGTCTAGAC TTGAAGTATC AGATGACCTG GAAAAAGTGT GCAATTGGGT AGTGGACACT 780

TGTTTACATA AGGGGAGTCG TGATAACATG AGTATTGTAC TAGTTTGTCT TTCAAATGCT 840

CCTAAGGTCT CAGATGAGGC AGTGAAAAAA GATGCAGAGT TGGATAAGCA CTTGGAATCA 900

CGGGTTGAAG AAATTATGGA GAAATCAGGT GAAGAAGGAA TGCCTGATCT TGCTCATGTT 960

ATTCGTATTT TATCTGCGGA GAATATTCCT AATTTACCAC CAGGAGGTGG TTTAGCTGGC 1020

AAGCGTAATA TTATTGAAGC TGTGTACAGT AGACTGAATC CACACAGAGA GAATGAGGGG 1080

GACCCTGGCG AAGCCGAGGA AAGTGGAACG CAGGGAAAAT TGGTGGAAGC GCTCAGGCAA 1140

ATGAGAATAA ATCATAGGGG GAACTACCGC CACCTTCTGG AAGAGATGCT GACTAGTTAC 1200

AGGCTAGCTA AGATGCAGGG AGAAGAGTGC ACTGCTGAAT CAGCTGCAGC TTCTGCTTCA 1260

GATAAT 1266

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++s++g+r emeda+t++ ++         ++ff+vyDGh+gs+va++cs++l e++

Q: 6     RYGLCSMQGWRVEMEDAHTAVVGIPHG----LDWSFFAVYDGHAGSRVANYCSTHLLEHI  61

         69****************985555443....34***************************

S: 62    aeele.........sseseerkvkkalakaFlstdeelkvleeksldidksGstavvali  112

         +++ +         + e++ ++vk+ ++++Fl++de ++++++ ++ +d+sGstav ++i

Q: 62    TNNEDfraaekpgsALEPSVENVKSGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMI  121

         ***99*********99********************************************

S: 113   kdsklyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvL  172

         +++++y++n+GdSravL rng+++  ++dHkp +++E+eRi++aggsv+ +   Rv+G+L

Q: 122   SPEHVYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSL  178

         ***************************************************...******

S: 173   avsRalGdlylk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavs  223

         avsRalGd+++k         ++v+pePev ++ + +edef+iLa+DG+wdv+snee+++

Q: 179   AVSRALGDYDYKcvdgkgpteQLVSPEPEVCEILRAEEDEFIILACDGIWDVMSNEELCE  238

         ************************************************************

S: 224   lvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

         +v+++le +++++++++ +v+++l++gs+dn+s+++v

Q: 239   FVKSRLEVSDDLEKVCNWVVDTCLHKGSRDNMSIVLV  275

         ********************************98875

Domain Sequence
(FASTA)

RYGLCSMQGW RVEMEDAHTA VVGIPHGLDW SFFAVYDGHA GSRVANYCST HLLEHITNNE 60

DFRAAEKPGS ALEPSVENVK SGIRTGFLKI DEYMRNFSDL RNGMDRSGST AVGVMISPEH 120

VYFINCGDSR AVLYRNGQVC FSTQDHKPCN PREKERIQNA GGSVMIQRVN GSLAVSRALG 180

DYDYKCVDGK GPTEQLVSPE PEVCEILRAE EDEFIILACD GIWDVMSNEE LCEFVKSRLE 240

VSDDLEKVCN WVVDTCLHKG SRDNMSIVLV 270

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013