EKS-GAG-00177

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00177

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	494.2	9.3E-149	4	287	284

Status

Unreviewed

Ensembl Protein

ENSGALP00000016441

UniProt Accession

E1C431;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000010119	ENSGALP00000016441	ENSGALT00000016460

Organism

Gallus gallus

Functional Description

Protein Length

459

Protein Sequence
(FASTA)

MEKYQVLGLI GEGSYGVVSR CRNKESGQVV AVKKFLESED NAAVRKIAVR EIKLLKQLRH 60

ENLVSLLEVY KKKKRWYLVF EFVDHTVLDD LEAFPNGLDY SRVRKYLFQI LRGIAFCHSQ 120

NIIHRDIKPE NILVSQSGVV KLCDFGFART LAASGEAYTD YVATRWYRAP ELLVGDTKYG 180

RAVDVWAIGC LVTEMLTGEP LFPGDSDIDQ LYHITKCLGN LIPRHQELFC KNPLFAGMRL 240

PEVKEAESLD RRYPKLSASV LDLAKKCLQI DPDKRPSCAE LLQSDFFNKD GFAERFAQEL 300

KLRIHKEARD HQSQKKSKIN RKDKDDAVEE RKMLGVQDFN TDPKSRDAKV FKVKCSKADG 360

EKAERSSDLS SLYDSAINPF KICSQTNLKD SSSNLHYIKN ADIVIPPINQ NVSPTMSSMV 420

PVPGNCNYRV DERSKNYLKP FLKQMKHSPA GHYSVSLTS 459

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ACCAGGTGCT GGGCCTCATC GGGGAGGGCA GCTACGGGGT GGTGAGCAGG 60

TGCAGGAATA AGGAGAGCGG GCAGGTGGTG GCTGTGAAAA AGTTCCTGGA GAGCGAGGAC 120

AACGCGGCAG TGAGGAAGAT CGCCGTGAGG GAGATCAAAC TGCTGAAGCA ACTCAGGCAT 180

GAGAATCTTG TGAGCCTGCT GGAAGTGTAT AAAAAGAAGA AACGGTGGTA TCTGGTGTTT 240

GAATTTGTGG ATCACACGGT GCTTGATGAT CTTGAGGCAT TTCCAAATGG ACTTGACTAC 300

AGCAGGGTTC GGAAATACTT ATTTCAGATT TTGAGAGGAA TAGCGTTTTG TCACAGCCAG 360

AACATAATAC ATCGGGATAT TAAGCCAGAG AACATACTGG TCTCCCAGTC AGGAGTGGTA 420

AAACTCTGTG ACTTCGGTTT TGCTCGCACG TTGGCAGCTT CTGGGGAAGC TTACACAGAC 480

TATGTGGCAA CTCGATGGTA CAGAGCTCCA GAGCTGCTGG TGGGAGACAC GAAATATGGC 540

AGGGCTGTGG ATGTGTGGGC TATTGGCTGT CTGGTAACAG AAATGCTCAC AGGAGAGCCT 600

CTGTTCCCTG GAGATTCAGA CATCGATCAG CTCTACCACA TCACCAAGTG CCTGGGTAAT 660

TTAATTCCAA GACACCAAGA GTTATTCTGT AAAAATCCCC TCTTTGCTGG CATGAGGTTG 720

CCTGAAGTGA AAGAGGCTGA ATCTCTGGAC AGACGATATC CTAAGCTCTC TGCTTCAGTG 780

CTAGATTTAG CCAAGAAGTG TTTGCAGATT GACCCAGACA AAAGACCATC CTGTGCTGAA 840

CTCTTGCAGA GCGATTTCTT TAACAAGGAT GGATTTGCTG AAAGATTTGC TCAGGAGCTT 900

AAATTAAGGA TTCACAAAGA AGCCAGAGAC CATCAATCAC AAAAAAAATC AAAAATCAAC 960

AGAAAGGATA AAGATGATGC TGTAGAAGAA AGAAAGATGC TTGGTGTACA GGATTTCAAC 1020

ACTGACCCAA AGAGCAGAGA TGCAAAGGTG TTCAAAGTGA AGTGTTCTAA AGCTGATGGA 1080

GAGAAAGCAG AGCGATCTTC CGACCTGAGC TCCCTCTATG ACAGTGCAAT CAACCCATTC 1140

AAAATATGCT CTCAGACCAA CCTGAAAGAT TCCAGTAGCA ACCTGCACTA CATCAAGAAT 1200

GCAGACATCG TTATTCCTCC CATTAACCAG AATGTTTCTC CCACTATGTC TTCGATGGTG 1260

CCTGTGCCTG GGAACTGCAA CTACAGAGTT GACGAAAGGA GTAAGAATTA CTTGAAACCA 1320

TTTTTAAAGC AAATGAAGCA TTCTCCAGCA GGCCATTACA GTGTAAGCTT GACTTCG 1377

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         y+ lg +GeGsyGvv +crnk++gq+va+kkflesed+ +v+kia+reikllkql+henl

Q: 4     YQVLGLIGEGSYGVVSRCRNKESGQVVAVKKFLESEDNAAVRKIAVREIKLLKQLRHENL  63

         889*********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+llev+++kk++ylvfe+vd+tvld+le +pnG+++++v+k+l+qil++i+fch++nii

Q: 64    VSLLEVYKKKKRWYLVFEFVDHTVLDDLEAFPNGLDYSRVRKYLFQILRGIAFCHSQNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sgvvklcdfGfar+laa+g++ytdyvatrwyrapellvgdtkyG++v

Q: 124   HRDIKPENILVSQSGVVKLCDFGFARTLAASGEAYTDYVATRWYRAPELLVGDTKYGRAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGcl++e+ltGeplfpg+sd+dqly+i+k+lG+liprhq++f kn++faG++lpev

Q: 184   DVWAIGCLVTEMLTGEPLFPGDSDIDQLYHITKCLGNLIPRHQELFCKNPLFAGMRLPEV  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++esl+++ypkl+ ++ldl+kkcl++dp++r sc+ell++++f

Q: 244   KEAESLDRRYPKLSASVLDLAKKCLQIDPDKRPSCAELLQSDFF  287

         *****************************************998

Domain Sequence
(FASTA)

YQVLGLIGEG SYGVVSRCRN KESGQVVAVK KFLESEDNAA VRKIAVREIK LLKQLRHENL 60

VSLLEVYKKK KRWYLVFEFV DHTVLDDLEA FPNGLDYSRV RKYLFQILRG IAFCHSQNII 120

HRDIKPENIL VSQSGVVKLC DFGFARTLAA SGEAYTDYVA TRWYRAPELL VGDTKYGRAV 180

DVWAIGCLVT EMLTGEPLFP GDSDIDQLYH ITKCLGNLIP RHQELFCKNP LFAGMRLPEV 240

KEAESLDRRY PKLSASVLDL AKKCLQIDPD KRPSCAELLQ SDFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013