| Tag | Content |
|---|
| EKPD ID | EPS-GAG-00076 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPP/PP2A | 419.6 | 1.6E-126 | 51 | 243 | 193 |
|
| Status | Reviewed |
| Ensembl Protein | ENSGALP00000016689 |
| UniProt Accession | P48463; |
| Protein Name | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform |
| Protein Synonyms/Alias | PP2A-alpha; |
| Gene Name | PPP2CA |
| Gene Synonyms/Alias | PPP2CA; |
| Ensembl Information | |
| Organism | Gallus gallus |
| Functional Description | PP2A can modulate the activity of phosphorylase B kinasecasein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. |
| Protein Length | 309 |
Protein Sequence
(FASTA) | | MEEKSFAKEL DQWIEQLNEC RQLSESQVRS LCEKAKEILT KESNVQEVRC PVTVCGDVHG 60 | | QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER ITILRGNHES 120 | | RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI 180 | | RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA 240 | | HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV 300 | | TRRTPDYFL 309 |
|
Nucleotide Sequence
(FASTA) | | ATGGAGGAGA AGAGCTTCGC CAAGGAGCTG GACCAGTGGA TCGAGCAGCT GAACGAGTGC 60 | | CGGCAGCTGA GCGAGAGCCA GGTCCGCAGC CTCTGCGAGA AGGCTAAAGA AATTCTTACA 120 | | AAAGAATCAA ATGTGCAAGA GGTACGTTGC CCTGTCACTG TCTGTGGGGA CGTCCATGGC 180 | | CAATTCCACG ATCTTATGGA ACTCTTCAGA ATCGGTGGGA AGTCTCCAGA CACAAATTAC 240 | | CTGTTCATGG GAGACTATGT GGACAGAGGC TACTACTCGG TGGAAACGGT GACTCTACTA 300 | | GTAGCGTTAA AGGTGCGTTA CCCAGAGCGC ATTACAATAC TGAGAGGAAA TCATGAAAGC 360 | | AGACAAATTA CACAAGTGTA TGGCTTTTAT GATGAATGTC TGCGGAAATA CGGCAATGCC 420 | | AATGTCTGGA AGTATTTCAC AGATCTGTTT GATTATCTTC CACTTACAGC TCTAGTTGAT 480 | | GGCCAGATAT TCTGTCTCCA CGGTGGCCTC TCTCCATCCA TAGATACACT GGATCATATC 540 | | AGGGCTCTGG ACCGCCTGCA GGAAGTTCCA CATGAGGGTC CAATGTGTGA TCTGTTATGG 600 | | TCGGATCCAG ATGATCGTGG CGGCTGGGGT ATATCTCCAC GTGGTGCCGG CTACACGTTT 660 | | GGGCAAGACA TTTCTGAAAC ATTTAATCAT GCCAACGGTC TTACACTGGT CTCCCGCGCT 720 | | CACCAACTCG TCATGGAGGG TTATAACTGG TGCCATGACC GAAATGTGGT GACCATTTTC 780 | | AGTGCGCCCA ATTACTGTTA CCGCTGTGGG AACCAGGCCG CTATCATGGA ACTAGATGAC 840 | | ACTTTAAAAT ATTCCTTCCT TCAGTTTGAC CCAGCACCTC GTCGTGGAGA GCCTCACGTT 900 | | ACCCGTCGTA CCCCAGACTA CTTCCTATAA 930 |
|
| Domain Profile | S: 1 pvtvcgdvhgqfhdllelfriggkspdtnylflgdyvdrgyysvetvtllvalkvryrer 60 | pvtvcgdvhgqfhdl+elfriggkspdtnylf+gdyvdrgyysvetvtllvalkvry+er | Q: 51 PVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPER 110 | 9*********************************************************** |
| S: 61 itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdgkifclhggl 120 | itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdg+ifclhggl | Q: 111 ITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL 170 | ************************************************************ |
| S: 121 spsidtldeiraldrlqevphegplcdllwsdpddregwgisprgagytfgqdiseqfnh 180 | spsidtld+iraldrlqevphegp+cdllwsdpddr+gwgisprgagytfgqdise+fnh | Q: 171 SPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNH 230 | ************************************************************ |
| S: 181 angleliarahql 193 | angl+l++rahql | Q: 231 ANGLTLVSRAHQL 243 | ************8 |
|
Domain Sequence
(FASTA) | | PVTVCGDVHG QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER 60 | | ITILRGNHES RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL 120 | | SPSIDTLDHI RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH 180 | | ANGLTLVSRA HQL 193 |
|
| Keyword | Centromere; Chromosome; Complete proteome; Cytoplasm; Cytoskeleton; Hydrolase; Iron; Manganese; Metal-binding; Methylation; Nucleus; Phosphoprotein; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |