EPS-GAG-00027

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00027

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	228.0	1.8E-67	94	344	251

Status

Unreviewed

Ensembl Protein

ENSGALP00000018364

UniProt Accession

F1P138;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1K

Gene Synonyms/Alias

PPM1K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000011266	ENSGALP00000018365	ENSGALT00000018387
ENSGALG00000011266	ENSGALP00000018364	ENSGALT00000018386

Organism

Gallus gallus

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSTAALIHLV RNGGYQVRRR ALLTSRLLQD EKRTTAECCI STSERRASRF DPDGSGRPAT 60

WDTFGIWDNR IDEPILLPPS IKYGKPIPKV SLSKVGCASH IGKRKENEDR FDYAQLTEDV 120

LYFAVYDGHG GAAAADFCAK NMERYIKEFA AQEENLEKVL NDAFLEINKA YERHAQLSAD 180

ATLMNSGTTA TVALLRDGIE LVVASVGDSR ALLCRKGKAM KLTIDHTPER KEEKERIRKC 240

GGFVAWNSLG QPHVNGRLAM TRSIGDLDLK SSGVIAQPET KRVQLHHADD GFLVLTTDGI 300

NFMVNSQEIC DFINQCHDPA EAAHVVTEQA MQYGTEDNST VVIVPFGAWG KYKNGEINFS 360

FSRSFASSGR WA 372

Nucleotide Sequence
(FASTA)

ATGTCAACAG CTGCTTTAAT CCATTTGGTA AGAAACGGAG GTTATCAAGT ACGAAGGAGA 60

GCCCTGCTGA CATCCCGCCT CTTGCAAGAC GAGAAGCGTA CGACAGCCGA GTGCTGCATT 120

TCCACCTCCG AACGCCGGGC ATCCCGCTTC GATCCGGACG GGAGCGGGCG GCCCGCCACA 180

TGGGACACCT TTGGCATCTG GGACAATCGC ATTGATGAAC CTATTCTCCT CCCACCTAGC 240

ATAAAGTATG GAAAGCCGAT TCCAAAAGTC AGCTTGAGCA AAGTGGGCTG TGCCAGCCAT 300

ATTGGGAAGC GGAAGGAAAA TGAAGACCGC TTTGATTACG CTCAGCTGAC TGAGGATGTC 360

CTGTACTTTG CGGTATACGA TGGACACGGC GGGGCGGCAG CAGCAGACTT CTGCGCTAAG 420

AACATGGAAA GATATATCAA GGAATTTGCT GCCCAGGAGG AGAACTTAGA AAAAGTTTTG 480

AACGATGCTT TTCTAGAAAT AAACAAAGCA TACGAAAGGC ATGCTCAGCT GTCTGCTGAT 540

GCAACTCTGA TGAACTCTGG GACCACTGCA ACGGTGGCCC TGCTGCGGGA TGGTATCGAG 600

CTGGTAGTGG CAAGCGTGGG TGACAGCCGT GCCCTGCTGT GTCGAAAAGG AAAGGCCATG 660

AAACTCACCA TTGACCATAC ACCAGAAAGG AAGGAGGAGA AGGAAAGGAT TAGGAAGTGC 720

GGTGGCTTCG TTGCCTGGAA CAGTTTGGGA CAACCTCATG TGAATGGTAG ACTTGCAATG 780

ACGCGGAGCA TAGGAGATTT GGATCTTAAA AGCAGTGGTG TGATAGCCCA GCCAGAAACA 840

AAAAGGGTTC AGTTGCATCA TGCAGATGAC GGCTTCCTGG TCCTTACTAC AGATGGCATT 900

AACTTCATGG TGAACAGTCA GGAGATCTGC GACTTCATCA ACCAGTGCCA CGATCCTGCT 960

GAAGCTGCCC ACGTTGTTAC TGAGCAGGCA ATGCAGTACG GCACTGAAGA TAATAGCACG 1020

GTTGTCATAG TGCCATTTGG AGCATGGGGA AAGTATAAAA ATGGTGAGAT CAACTTCTCC 1080

TTCAGCCGCA GTTTTGCCTC CAGTGGGAGG TGGGCGTGA 1119

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         +vg++s  g+r+e ed++++    ++ +e    + +f+vyDGhgg  +a+fc++++++++

Q: 94    KVGCASHIGKRKENEDRFDY----AQLTE---DVLYFAVYDGHGGAAAADFCAKNMERYI  146

         57999999999999999976....33322...289*************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidk....sGstavvalikds.k  116

         +e       +e++++k+l++aFl++ ++++   + s d  +    sG+ta+val++d  +

Q: 147   KEFAA----QEENLEKVLNDAFLEINKAYERHAQLSAD--AtlmnSGTTATVALLRDGiE  200

         **977....9*******************444444333..24688*************9*

S: 117   lyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd.ga.RvlGvLav  174

         l+va vGdSra+Lcr+gka++l+ dH+p+r++E+eRi++ gg v+ ++ g+ +v+G La+

Q: 201   LVVASVGDSRALLCRKGKAMKLTIDHTPERKEEKERIRKCGGFVAWNSlGQpHVNGRLAM  260

         ********************************************98889999********

S: 175   sRalGdlylkpy.vtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekk  232

         +R++Gdl+lk+  v+++Pe+  ++l++ d+ fl+L +DG+  +v+++e++++++++++

Q: 261   TRSIGDLDLKSSgVIAQPETKRVQLHHADDgFLVLTTDGINFMVNSQEICDFINQCHD--  318

         **********655*********************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + eaa+ ++++a+++g++dn ++++v

Q: 319   --PAEAAHVVTEQAMQYGTEDNSTVVIV  344

         ..*********************88775

Domain Sequence
(FASTA)

KVGCASHIGK RKENEDRFDY AQLTEDVLYF AVYDGHGGAA AADFCAKNME RYIKEFAAQE 60

ENLEKVLNDA FLEINKAYER HAQLSADATL MNSGTTATVA LLRDGIELVV ASVGDSRALL 120

CRKGKAMKLT IDHTPERKEE KERIRKCGGF VAWNSLGQPH VNGRLAMTRS IGDLDLKSSG 180

VIAQPETKRV QLHHADDGFL VLTTDGINFM VNSQEICDFI NQCHDPAEAA HVVTEQAMQY 240

GTEDNSTVVI V 251

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013