EKS-GAG-00328

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00328

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	358.2	3.4E-107	361	620	260

Status

Unreviewed

Ensembl Protein

ENSGALP00000018719

UniProt Accession

F1NZH4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K2

Gene Synonyms/Alias

MAP3K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000011502	ENSGALP00000018718	ENSGALT00000018741
ENSGALG00000011502	ENSGALP00000018719	ENSGALT00000018742

Organism

Gallus gallus

Functional Description

Protein Length

624

Protein Sequence
(FASTA)

ADEQQALNSI MQDLAVLHKA SRPALPQQET GKPKSSSPKK QNDVRVKFEH RGEKRILQLP 60

RPVKLEDLVA KAKVAFGQTM DLHYCNNELV IPLTTQDDLD KAVELLDRSV HMKSLKILLV 120

IHGNTQSPSV NNVEPLPSLE DLDNTVFGVT ERKRRLSVIV GSNNRDRSSP PPGYIPDELH 180

QVARNGSFTS INSEGEFIPE SMDQMLDPLS LSSPENSGSG SCPSLDSPLD GDNYPKSRMP 240

RAQSYPDNHQ EFSEYDIPIF EKFGKGGTYP RRYHISYHQQ DYNDGRKTFP RARRTQGNSF 300

RSPVSFSPTD HSLSTSSGSS VFTPEYEDNR MRRRGSDIDN PTLTVMDISP PSRSPRAPTN 360

WRLGKLLGQG AFGRVYLCYD ADTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 420

ERIVQYYGFL RDPPERTLSI FMEYMPGGSI KDQLKSYGAL TENVTRKYTR QILEGVLYLH 480

TNMIVHRDIK GANILRDSAG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 540

EGYGRKADIW SVGCTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPQLPPH VSDHARDFLK 600

RIFIEAKLRP FADELLRHTF AHYH 624

Nucleotide Sequence
(FASTA)

GCAGATGAGC AGCAAGCTTT GAATTCAATC ATGCAGGATT TGGCTGTGCT TCATAAGGCC 60

AGTCGTCCTG CACTGCCCCA ACAAGAAACA GGAAAACCAA AGTCATCTTC ACCTAAAAAA 120

CAGAACGATG TTAGAGTCAA ATTTGAACAT CGAGGTGAAA AAAGGATACT CCAATTACCC 180

AGGCCTGTCA AGCTTGAAGA TCTTGTAGCT AAAGCTAAGG TTGCGTTTGG ACAGACTATG 240

GATTTACATT ACTGCAATAA TGAGCTTGTA ATTCCATTAA CCACGCAGGA TGACCTGGAC 300

AAAGCTGTTG AACTGCTTGA CCGTAGTGTT CATATGAAGA GTCTGAAGAT ATTGCTTGTA 360

ATACACGGAA ATACACAGTC ACCCAGTGTA AATAATGTGG AACCCCTACC CTCACTGGAA 420

GATTTAGATA ATACAGTGTT CGGTGTGACA GAGAGAAAAA GGCGGCTTTC TGTAATAGTA 480

GGCTCTAATA ATCGTGATAG GAGTTCACCT CCCCCAGGAT ACATTCCAGA TGAGCTGCAT 540

CAAGTGGCCC GAAATGGGTC GTTCACCAGT ATCAACAGTG AGGGTGAATT CATTCCAGAA 600

AGCATGGATC AGATGCTGGA TCCGCTGTCT TTGAGCAGTC CTGAAAATTC TGGCTCAGGA 660

AGCTGTCCCT CACTTGACAG CCCTTTAGAT GGAGACAACT ATCCCAAATC TCGGATGCCG 720

AGAGCACAGA GCTATCCAGA TAACCATCAG GAATTCTCAG AGTATGATAT CCCAATATTT 780

GAGAAGTTTG GAAAGGGGGG AACGTATCCC CGAAGATACC ATATCTCATA TCATCAACAA 840

GATTACAATG ACGGTCGTAA AACTTTTCCA AGAGCCAGGA GGACGCAGGG GAACAGCTTC 900

CGGTCACCCG TTAGTTTCAG TCCCACTGAT CACTCGCTGA GCACCAGCAG TGGGAGCAGT 960

GTCTTCACAC CAGAATATGA GGATAACAGA ATGAGGAGGA GGGGAAGTGA CATTGACAAT 1020

CCTACCTTGA CAGTCATGGA CATCAGCCCA CCCAGTCGCT CACCACGAGC TCCAACTAAT 1080

TGGAGACTTG GCAAACTGCT GGGTCAGGGT GCATTTGGCA GAGTATATCT GTGTTATGAT 1140

GCTGATACCG GAAGAGAACT GGCTGTTAAA CAAGTGCAGT TTGATCCTGA TAGTCCAGAA 1200

ACTAGCAAGG AAGTAAACGC TCTTGAATGT GAGATTCAGT TGCTGAAAAA TCTGCTGCAT 1260

GAGAGGATCG TTCAGTACTA TGGCTTCTTG AGGGACCCAC CAGAAAGAAC ACTCTCTATA 1320

TTCATGGAAT ACATGCCAGG GGGTTCCATC AAAGACCAAT TAAAATCGTA TGGAGCACTG 1380

ACAGAGAACG TGACTCGCAA ATACACGCGG CAGATTTTAG AAGGCGTTCT CTATTTGCAC 1440

ACAAACATGA TTGTCCATCG AGATATCAAA GGAGCAAATA TTCTGCGAGA TTCGGCAGGC 1500

AATGTGAAGC TGGGTGACTT TGGTGCCAGC AAACGACTGC AGACCATCTG TCTGTCTGGT 1560

ACAGGAATGA AGTCTGTCAC AGGAACTCCG TACTGGATGA GTCCAGAAGT TATCAGTGGA 1620

GAAGGGTACG GCAGAAAAGC AGATATCTGG AGCGTAGGTT GTACAGTGGT AGAAATGCTC 1680

ACTGAGAAGC CCCCATGGGC AGAATTTGAA GCAATGGCTG CCATCTTTAA GATTGCCACT 1740

CAGCCAACCA ATCCCCAGTT ACCACCTCAT GTCTCAGACC ATGCTCGGGA TTTCCTGAAA 1800

AGGATTTTTA TCGAGGCCAA GCTGCGACCA TTTGCAGATG AACTGCTAAG ACACACGTTT 1860

GCACACTATC ACTAA 1875

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++d+dtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 361   WRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  420

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  +  e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg+ yLH

Q: 421   ERIVQYYGFlrDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLH  480

         *********6566799********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

          ++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 481   TNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  540

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs+gc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s++++d

Q: 541   E--GYGRKADIWSVGCTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPQLPPHVSDHARD  597

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhef  262

         fl++++ +++k rp a+eLL+h+f

Q: 598   FLKRIF-IEAKLRPFADELLRHTF  620

         ******.899************99

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD ADTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGFL RDPPERTLSI FMEYMPGGSI KDQLKSYGAL TENVTRKYTR QILEGVLYLH 120

TNMIVHRDIK GANILRDSAG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVGCTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPQLPPH VSDHARDFLK 240

RIFIEAKLRP FADELLRHTF 260

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013