EKS-GAG-00398

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00398

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	569.8	7.5E-172	1	251	251

Status

Unreviewed

Ensembl Protein

ENSGALP00000019616

UniProt Accession

E1C3I7;

Protein Name

Protein Synonyms/Alias

Calcium/calmodulin-dependent protein kinase type II delta chain;

Gene Name

CAMK2D

Gene Synonyms/Alias

CAMK2D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012036	ENSGALP00000036906	ENSGALT00000037701
ENSGALG00000012036	ENSGALP00000019616	ENSGALT00000019642

Organism

Gallus gallus

Functional Description

Protein Length

456

Protein Sequence
(FASTA)

RGAFSVVRRC MKITTGQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS 60

EEGFHYLVFD LVTGGELFED IVAREYYSEA DASHCIQQIL ESVNHCHLNG IVHRDLKPEN 120

LLLASKSKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDMWACG 180

VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV TPEAKDLINK MLTINPAKRI 240

TASEALKHPW ICQRSTVASM MHRQETVDCL KKFNARRKLK GAILTTMLAT RNFSAAKSLL 300

KKPDGVKEST ESSNTTIEDE DVKARKQEII KVTEQLIEAI NNGDFEAYTK ICDPGLTSFE 360

PEALGNLVEG MDFHRFYFEN ALSKSNKPIH TIILNPHVHL VGDDAACIAY IRLTQYMDGT 420

GMPKTMQSEE TRVWHRRDGK WQNVHFHRSG SPTVPI 456

Nucleotide Sequence
(FASTA)

AGAGGGGCGT TCTCGGTCGT GAGGCGATGT ATGAAAATCA CCACAGGACA GGAGTATGCT 60

GCCAAAATCA TCAACACCAA AAAGCTCTCA GCCAGGGATC ACCAGAAACT GGAAAGAGAA 120

GCTAGAATCT GTCGTCTCTT GAAGCATCCT AATATTGTGC GGCTTCATGA CAGCATATCA 180

GAAGAAGGAT TCCATTACTT AGTCTTTGAC TTAGTCACTG GAGGTGAATT GTTTGAAGAT 240

ATAGTTGCAA GAGAGTATTA CAGTGAAGCA GATGCCAGTC ATTGTATACA GCAGATTCTA 300

GAAAGTGTTA ATCATTGTCA TCTAAATGGC ATAGTTCACA GAGACCTGAA GCCTGAGAAC 360

TTACTTTTAG CTAGCAAATC CAAGGGAGCA GCAGTAAAAC TGGCAGACTT TGGATTGGCT 420

ATAGAAGTCC AAGGGGAACA ACAGGCTTGG TTTGGCTTTG CTGGCACTCC AGGATACCTT 480

TCTCCAGAAG TTTTACGGAA AGATCCATAT GGAAAACCTG TGGATATGTG GGCATGCGGT 540

GTCATTCTGT ATATCCTCCT GGTGGGTTAT CCTCCTTTCT GGGATGAAGA CCAGCACAGA 600

CTTTACCAGC AGATAAAGGC TGGTGCTTAT GATTTTCCCT CACCAGAATG GGATACAGTG 660

ACCCCTGAAG CAAAAGACCT TATCAATAAA ATGCTTACCA TCAACCCTGC AAAACGTATC 720

ACAGCTTCAG AAGCACTAAA GCATCCATGG ATCTGTCAAC GTTCCACTGT TGCCTCTATG 780

ATGCACAGAC AGGAGACGGT AGATTGCTTG AAGAAATTCA ATGCAAGAAG AAAACTAAAG 840

GGGGCCATTT TGACAACTAT GCTGGCTACC AGAAATTTCT CAGCAGCCAA GAGTTTACTG 900

AAAAAGCCAG ATGGAGTTAA GGAGTCCACA GAGAGTTCCA ATACAACCAT TGAAGATGAA 960

GATGTGAAAG CTCGTAAGCA GGAGATTATC AAGGTTACTG AGCAGTTGAT TGAAGCTATC 1020

AACAATGGGG ACTTTGAAGC TTACACGAAA ATCTGTGATC CAGGCCTTAC ATCCTTTGAA 1080

CCTGAAGCTT TGGGTAATCT AGTAGAAGGG ATGGACTTCC ATCGGTTTTA CTTTGAAAAT 1140

GCTTTATCCA AAAGTAATAA GCCAATCCAC ACCATTATCC TCAATCCTCA CGTCCACCTT 1200

GTGGGTGATG ATGCTGCTTG CATTGCATAT ATACGGCTCA CGCAGTACAT GGATGGAACT 1260

GGGATGCCAA AGACAATGCA GTCAGAGGAA ACGCGGGTCT GGCACCGTCG TGACGGGAAG 1320

TGGCAGAATG TTCACTTTCA CCGTTCAGGG TCACCAACAG TACCTATC 1368

Domain Profile

S: 9     kgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsis  68

         +gafsvvrrc+k+ttgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsis

Q: 1     RGAFSVVRRCMKITTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIS  60

         69**********************************************************

S: 69    eegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvvhrdlkpen  128

         eegfhylvfdlvtggelfedivareyyseadashciqqilesv+h+h ng+vhrdlkpen

Q: 61    EEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPEN  120

         ************************************************************

S: 129   lllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpvdlwacg  188

         lllask+kgaavkladfglaievqg+qqawfgfagtpgylspevlrkdpygkpvd+wacg

Q: 121   LLLASKSKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACG  180

         ************************************************************

S: 189   vilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakri  248

         vilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakri

Q: 181   VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRI  240

         ************************************************************

S: 249   tadealkhpwi  259

         ta+ealkhpwi

Q: 241   TASEALKHPWI  251

         **********8

Domain Sequence
(FASTA)

RGAFSVVRRC MKITTGQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS 60

EEGFHYLVFD LVTGGELFED IVAREYYSEA DASHCIQQIL ESVNHCHLNG IVHRDLKPEN 120

LLLASKSKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDMWACG 180

VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV TPEAKDLINK MLTINPAKRI 240

TASEALKHPW I 251

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Dipodomys ordii"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0031594	; C:neuromuscular junction
GO:0005634	; C:nucleus
GO:0030315	; C:T-tubule
GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity
GO:0006816	; P:calcium ion transport
GO:0000082	; P:G1/S transition of mitotic cell cycle
GO:0010613	; P:positive regulation of cardiac muscle hypertrophy
GO:0046777	; P:protein autophosphorylation
GO:0060341	; P:regulation of cellular localization

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013