EKS-GAG-00176

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00176

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	527.1	8.7E-159	4	287	284

Status

Unreviewed

Ensembl Protein

ENSGALP00000020061

UniProt Accession

E1C5K5;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012295	ENSGALP00000020061	ENSGALT00000020088

Organism

Gallus gallus

Functional Description

Protein Length

352

Protein Sequence
(FASTA)

MERYEKLGKV GEGSYGVVFK CRNRETGQIV AIKKFLESEE DPVIRKIALR EVRMLKQLKH 60

PNLVNLLEVF RRKRKLHLVF EYCDHTVLHE LDKHPRGVPE QLVRSITWQT LQAVNFCHKH 120

NCIHRDVKPE NILITKHSVI KLCDFGFARM LTGPGDYYTD YVATRWYRSP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGVP LWPGKSDVDQ LYLIRRTLGD LIPRHQQVFS TNQFFSGVTI 240

PDPESMEPLE MKFPSISYPA LALMKGCLHM DPAERQTCEQ LLQHPYFDSV REAGDVGKEH 300

EKAARRPAKL TRKHVPGFQY LPQLSSSNVL PALDSKKYFC KTRKSNYHFP NI 352

Nucleotide Sequence
(FASTA)

ATGGAGCGGT ACGAGAAGCT GGGCAAGGTC GGGGAGGGCT CCTACGGCGT CGTCTTCAAG 60

TGCCGCAACA GGGAGACGGG GCAGATCGTG GCCATCAAGA AGTTCCTGGA GTCCGAGGAG 120

GACCCGGTGA TCCGGAAGAT CGCGCTGCGG GAGGTCCGCA TGCTGAAGCA ACTGAAACAC 180

CCCAACCTGG TGAACCTGCT GGAGGTGTTC AGGAGGAAGA GGAAGCTGCA CCTGGTCTTT 240

GAGTACTGCG ACCACACCGT TCTCCACGAG CTGGACAAGC ACCCCCGGGG GGTCCCGGAG 300

CAGCTGGTCA GGAGCATTAC CTGGCAGACC CTCCAAGCTG TGAACTTTTG TCACAAACAC 360

AACTGCATCC ATCGAGATGT AAAGCCAGAA AACATCCTGA TAACGAAGCA CTCTGTCATC 420

AAACTCTGTG ACTTCGGATT TGCTCGCATG CTGACTGGCC CAGGTGATTA CTACACAGAC 480

TACGTGGCAA CCAGGTGGTA CCGCTCCCCA GAGCTGCTGG TGGGGGACAC GCAGTATGGC 540

CCTCCTGTGG ACGTGTGGGC AATAGGCTGT GTCTTTGCGG AGCTGCTCTC CGGGGTGCCA 600

CTGTGGCCCG GCAAGTCAGA CGTGGACCAG CTGTACCTCA TCCGGAGAAC ATTGGGGGAT 660

CTTATTCCCA GGCACCAGCA AGTGTTCAGC ACCAACCAGT TCTTCAGCGG CGTAACGATT 720

CCAGACCCAG AGAGCATGGA GCCATTGGAA ATGAAGTTTC CTAGTATTTC ATACCCTGCT 780

TTAGCTCTCA TGAAGGGCTG CCTTCATATG GACCCTGCGG AGAGGCAGAC GTGTGAGCAG 840

CTGCTCCAGC ACCCCTATTT TGACAGCGTT AGGGAGGCAG GAGATGTGGG GAAAGAACAT 900

GAAAAAGCAG CTCGGAGACC AGCCAAGCTG ACACGGAAGC ACGTGCCGGG GTTCCAGTAC 960

CTGCCTCAGT TAAGCAGCAG CAACGTCCTG CCAGCTTTGG ACAGCAAGAA GTACTTCTGC 1020

AAAACGAGGA AATCCAACTA CCATTTCCCT AACATCTAA 1059

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yeklgkvGeGsyGvv+kcrn++tgqivaikkflese+d++++kialre+++lkqlkh+nl

Q: 4     YEKLGKVGEGSYGVVFKCRNRETGQIVAIKKFLESEEDPVIRKIALREVRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk+kl+lvfey+d+tvl+el+++p+Gv+e+lv++i++q+l+a++fchk+n+i

Q: 64    VNLLEVFRRKRKLHLVFEYCDHTVLHELDKHPRGVPEQLVRSITWQTLQAVNFCHKHNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfar+l++pgd+ytdyvatrwyr+pellvgdt+yG++v

Q: 124   HRDVKPENILITKHSVIKLCDFGFARMLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+ir+tlG+liprhq++fs+n++f+Gv++p++

Q: 184   DVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRRTLGDLIPRHQQVFSTNQFFSGVTIPDP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e++e+le k+p++++ +l l+k+cl++dpaer +ce+ll+h+yf

Q: 244   ESMEPLEMKFPSISYPALALMKGCLHMDPAERQTCEQLLQHPYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKLGKVGEG SYGVVFKCRN RETGQIVAIK KFLESEEDPV IRKIALREVR MLKQLKHPNL 60

VNLLEVFRRK RKLHLVFEYC DHTVLHELDK HPRGVPEQLV RSITWQTLQA VNFCHKHNCI 120

HRDVKPENIL ITKHSVIKLC DFGFARMLTG PGDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGVPLWP GKSDVDQLYL IRRTLGDLIP RHQQVFSTNQ FFSGVTIPDP 240

ESMEPLEMKF PSISYPALAL MKGCLHMDPA ERQTCEQLLQ HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

gga:423575

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013