EKS-GAG-00351

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00351

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	412.7	6.0E-124	52	310	259

Status

Unreviewed

Ensembl Protein

ENSGALP00000020150

UniProt Accession

F1NAF6;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17A

Gene Synonyms/Alias

STK17A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012351	ENSGALP00000020150	ENSGALT00000020177

Organism

Gallus gallus

Functional Description

Protein Length

406

Protein Sequence
(FASTA)

MSPEEKPPPG RSHDECSPQP AAGRGRRRGG LLTEIRTPIR TEPFQQRYSL SPGRELGRGK 60

FAVVKKCIQK DTEREFAAKF MRKRRKGQDC RMEIIHEIAV LELAQCNLWV INLHEVYETA 120

TEMILVLEYA AGGEIFDQCV AEREEAFKEK DVKRLMKQIL EGVSFLHRNN VVHLDLKPQN 180

ILLTSKSPLG DIKIVDFGLS RIVKSSEELR EIMGTPEYVA PEILSYDPIS TATDMWSIGV 240

LAYIMLTGIS PFLGDDKQET FLNISQMNVC YTGEDFDLIS ESAVDFMKTL LVKKPEERAT 300

AEECLQHPWL EQSDEPTCRA WSKSARRENS DVIQKNADSA SEKPVDVEKA EEEESVITEE 360

LIVVASYTLG QCRQSEKEKA TEQKAISKRF KFEEPLLQEI PGEFIY 406

Nucleotide Sequence
(FASTA)

ATGAGCCCCG AAGAGAAGCC GCCGCCCGGC CGCTCCCACG ATGAGTGCTC ACCTCAGCCT 60

GCTGCCGGCC GGGGCCGAAG GCGAGGCGGT TTGCTGACAG AGATCCGCAC GCCTATCCGC 120

ACCGAGCCCT TCCAGCAGCG CTACAGCCTC AGCCCCGGCA GGGAGCTCGG CAGAGGAAAA 180

TTTGCAGTGG TGAAGAAATG TATCCAGAAA GACACCGAAA GAGAATTTGC AGCAAAATTC 240

ATGAGAAAAA GAAGAAAGGG CCAAGACTGT CGGATGGAAA TAATCCATGA AATTGCAGTC 300

CTTGAATTGG CACAATGCAA TCTTTGGGTC ATTAACCTTC ATGAAGTTTA TGAAACTGCA 360

ACTGAGATGA TTTTAGTCCT GGAATATGCT GCTGGAGGTG AAATCTTTGA CCAGTGTGTT 420

GCTGAAAGAG AGGAGGCCTT CAAAGAGAAA GATGTGAAAC GACTAATGAA GCAGATCTTA 480

GAAGGAGTTT CATTCTTGCA CAGAAACAAT GTTGTTCATC TTGACTTAAA GCCACAAAAC 540

ATTCTACTAA CCAGTAAGTC TCCACTGGGA GACATAAAGA TAGTAGATTT TGGCCTTTCC 600

AGGATAGTGA AGAGCAGTGA GGAATTAAGA GAAATTATGG GAACTCCAGA ATATGTAGCT 660

CCTGAAATTC TGAGTTATGA CCCAATCAGT ACAGCAACCG ATATGTGGAG CATTGGAGTA 720

CTGGCATATA TTATGCTAAC AGGGATATCA CCCTTCTTAG GGGATGATAA ACAAGAAACA 780

TTCTTAAATA TATCTCAAAT GAATGTATGT TACACTGGAG AAGACTTTGA CCTCATATCA 840

GAGTCTGCTG TGGATTTCAT GAAAACTTTG CTGGTGAAGA AACCAGAGGA ACGGGCAACT 900

GCTGAAGAAT GTCTCCAGCA CCCCTGGTTA GAACAAAGTG ATGAACCTAC TTGCAGGGCC 960

TGGAGTAAGA GTGCAAGAAG GGAGAACAGT GATGTCATCC AGAAAAATGC AGATTCTGCT 1020

TCTGAAAAAC CTGTAGATGT TGAGAAAGCT GAGGAGGAAG AGTCAGTGAT TACAGAAGAG 1080

CTAATTGTAG TGGCTTCGTA TACATTGGGA CAATGTAGGC AGTCAGAAAA AGAAAAAGCA 1140

ACTGAGCAGA AAGCCATTTC CAAACGATTT AAGTTTGAAG AACCACTGCT GCAAGAAATA 1200

CCAGGAGAAT TCATTTACTG A 1221

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

          g+elg+Gkfavv+kc++k+t +e+aakf++krr    +++++r+ei +e+avl++++ +

Q: 52    PGRELGRGKFAVVKKCIQKDTEREFAAKFMRKRR----KGQDCRMEIIHEIAVLELAQCN  107

         589*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

          +vinlhevye+++++il+le++aGGe+fd  +++++e+++e+++++l+kqilegv +lh

Q: 108   LWVINLHEVYETATEMILVLEYAAGGEIFDqcVAEREEAFKEKDVKRLMKQILEGVSFLH  167

         ******************************988899************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

          +++vhldlkP+nill++k+ p gdik++dfGlsr +++++el+ei+GtPe+vaPei++y

Q: 168   RNNVVHLDLKPQNILLTSKS-PLGDIKIVDFGLSRIVKSSEELREIMGTPEYVAPEILSY  226

         ********************.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p+s++tdmwsiGv++yi+l+g+sPflGd+kqet+lnis++n+ +  e f+ +se+a+df

Q: 227   DPISTATDMWSIGVLAYIMLTGISPFLGDDKQETFLNISQMNVCYTGEDFDLISESAVDF  286

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         +++llvk+pe+r+t+eecl+h+wl

Q: 287   MKTLLVKKPEERATAEECLQHPWL  310

         ***********************7

Domain Sequence
(FASTA)

PGRELGRGKF AVVKKCIQKD TEREFAAKFM RKRRKGQDCR MEIIHEIAVL ELAQCNLWVI 60

NLHEVYETAT EMILVLEYAA GGEIFDQCVA EREEAFKEKD VKRLMKQILE GVSFLHRNNV 120

VHLDLKPQNI LLTSKSPLGD IKIVDFGLSR IVKSSEELRE IMGTPEYVAP EILSYDPIST 180

ATDMWSIGVL AYIMLTGISP FLGDDKQETF LNISQMNVCY TGEDFDLISE SAVDFMKTLL 240

VKKPEERATA EECLQHPWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:2000377	; P:regulation of reactive oxygen species metabolic process

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013