EPS-GAG-00067

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00067

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	246.8	1.8E-73	7	177	171

Status

Unreviewed

Ensembl Protein

ENSGALP00000020320

UniProt Accession

F1NE19;

Protein Name

Protein Synonyms/Alias

Gene Name

TNS3

Gene Synonyms/Alias

TNS3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012447	ENSGALP00000020320	ENSGALT00000020347

Organism

Gallus gallus

Functional Description

Protein Length

1314

Protein Sequence
(FASTA)

QSADFDHIME EGYELDLTYI TERIIAVSFP ADCSEETYLH NLQDVTRMLK SKHGNNYLVL 60

NLSEKRYDLT KLNPKIMDVG WPDLHAPPLD KMCTICKAME SWLNSDPQRV VVIHCKGGRG 120

RIGVVISSYM HFTSVSTSAD QALDRFAMKK FFDDKVSALM QPSQKRYVQF LSGLLSGSVK 180

MNTASLFLHH VILHGIPSFD AGGACRPFLK LYQATQPVYT SGIYSVESEH QNRICIAIEP 240

AQLLKGDVML KCYHKKYRSA TRDVIFRLQF HTGAIQGYGL VFGKEDLDSA NKDDRFPDNG 300

KVELVFSGTP EKVQGCEHLQ NDHGVVVDHN TSDPLIRWDS YENMSSDGEG SVKNHLLHTQ 360

GPIDGSLYAK VRKKSSSDGS IPGVAQGIPV TSSPDHRDHT LSVSSDSGHS TASVRTDKTE 420

ERLIPGVKRV LSPQEKAELD KLLSGFGNLS CPKSSQNSLL SDGFGSNTGE DHHCAIAPDL 480

GIGVDPLYSS QQLQRNPCVS PHPQAYDPSE GTLKKRWIMV FFFQSMSKMP LCIASCEKRS 540

VPQGLAQNFY KYPVSISQKV YNELGLQGPG FVLAFIIQIK GESSGAYPCG VSQGAKLASP 600

AICLQCFRFA KMSWTEGFSS KVGKELLHPV YPHPSVMLQP WACGHYELKY SDTSCLHQLE 660

IFQKDHKECF YTCCPGKLTI HGFYTYVLVF LIGKLKEQYC VLKKTVSRSL GEGKNFYHDG 720

LHRPSSHHCA EQSEMHPALC IMLHELTCVI AGQFYFGTSE LVSEGMVIFS EMLESKIFRA 780

GTMKQGSGVF TPRDIICRCM REISSDINSC ALTSVFQSKS SVKKKKRKKK KKKKKEKIKP 840

GAVLLCYRSS KRTNGVDHHS GPSILQPPCC KYNSKNQWPE TRMIGVHRNG NKLSSFYTTM 900

SPCTASSNSS VPVGESYFVD NYRWSHPHSL LPLLHSPSPP SFPTPLFSRP ACYQTWNLHS 960

QPPLPEKKRS SEGDHSFVSI SPSSSGFSSP HSGSTISIPF PSVLPDFSNT GKTSLLPENT 1020

AEKQVTVKFV QDTSKFWYKP DISREQAIAV LKDKEPGSFV VRDSHSFRGA YGLAIKVAVP 1080

PPSVLQMNNT VGDLSNELVR HFLIECSQKG VHLKGCPNEP CFGSLTALVY QHSITPLALP 1140

CKLLIPNRDP LEEMAETSPQ TAANSATELL KQGAACNVWY LNSVEMESLT GYQAVQKALS 1200

LTLMQDPSPI STIVHFKVSA QGITLTDNQR KLFFRRHYPV NTVIFCALDP QDRKWTSRWM 1260

KDGLSAKVFG FVARKQGSGT DNVCHLFAEH DPEQPASAIV NFVSKVMIGS QKKI 1314

Nucleotide Sequence
(FASTA)

CAAAGTGCAG ACTTTGATCA CATTATGGAG GAAGGCTATG AACTTGACCT CACTTACATC 60

ACAGAACGGA TCATTGCTGT GTCCTTCCCT GCTGACTGTT CTGAGGAAAC GTACCTCCAC 120

AATCTACAAG ATGTAACACG AATGCTCAAA TCCAAACATG GGAATAATTA CCTGGTACTA 180

AACCTTTCTG AAAAGAGGTA TGACCTTACC AAGCTTAACC CAAAGATTAT GGATGTGGGT 240

TGGCCTGATC TTCATGCCCC ACCTCTTGAT AAGATGTGTA CCATCTGCAA AGCTATGGAA 300

TCATGGCTAA ACAGTGATCC TCAACGCGTG GTGGTGATCC ATTGCAAAGG AGGAAGAGGA 360

AGGATTGGCG TAGTCATATC ATCGTATATG CATTTCACCA GTGTTTCTAC AAGTGCTGAT 420

CAGGCTCTAG ACAGATTTGC TATGAAGAAA TTCTTTGATG ATAAAGTTTC AGCTTTAATG 480

CAGCCATCCC AGAAAAGATA TGTGCAATTT CTAAGTGGCC TTCTATCTGG ATCCGTGAAA 540

ATGAATACAG CTTCACTTTT CCTGCACCAC GTTATCCTTC ATGGCATCCC AAGCTTTGAT 600

GCTGGTGGAG CTTGTCGGCC TTTTCTGAAG TTATACCAAG CTACCCAACC CGTATATACA 660

TCTGGAATAT ATAGTGTAGA GTCAGAACAT CAAAACCGAA TCTGCATTGC TATAGAGCCA 720

GCCCAGCTTT TGAAAGGAGA TGTTATGCTG AAGTGTTATC ATAAAAAATA CCGATCAGCT 780

ACTCGTGATG TGATTTTTCG CCTTCAGTTT CATACTGGAG CTATTCAAGG ATATGGGTTG 840

GTGTTTGGTA AAGAGGATTT AGACAGTGCC AATAAAGATG ATCGTTTCCC TGATAATGGC 900

AAAGTGGAAT TAGTGTTTTC AGGAACTCCA GAGAAAGTTC AAGGATGTGA ACACCTTCAG 960

AATGATCATG GAGTGGTAGT TGATCACAAT ACCTCAGACC CGCTAATACG CTGGGACTCC 1020

TATGAAAATA TGAGCTCTGA TGGAGAAGGC TCAGTAAAGA ACCACTTGCT GCATACCCAA 1080

GGTCCCATTG ATGGCAGTCT GTATGCAAAA GTAAGAAAGA AGAGCTCTTC AGACGGCAGC 1140

ATCCCTGGTG TTGCTCAAGG TATTCCTGTG ACCAGCAGTC CTGATCACAG AGATCATACC 1200

CTGTCTGTCA GCAGTGACTC AGGACATTCA ACAGCTTCTG TCAGGACAGA CAAAACTGAA 1260

GAACGCCTTA TACCAGGAGT CAAACGGGTT TTGAGCCCAC AGGAGAAGGC AGAACTGGAC 1320

AAACTACTTA GTGGCTTTGG TAACTTGAGT TGCCCCAAGA GCAGTCAGAA CTCACTTCTC 1380

TCAGATGGCT TTGGAAGTAA CACAGGGGAA GACCATCACT GTGCCATTGC CCCAGACCTG 1440

GGAATTGGTG TGGATCCCCT CTATTCATCT CAGCAATTGC AAAGGAATCC TTGTGTCTCA 1500

CCCCATCCTC AAGCCTATGA CCCAAGTGAA GGGACACTTA AAAAGCGTTG GATTATGGTT 1560

TTTTTTTTTC AGAGCATGTC CAAAATGCCA CTGTGTATTG CGAGCTGTGA GAAACGAAGT 1620

GTTCCACAAG GATTAGCACA GAACTTTTAC AAGTACCCAG TTTCTATATC ACAAAAAGTG 1680

TATAATGAGT TGGGCTTACA AGGGCCAGGG TTTGTGTTAG CTTTCATTAT TCAAATAAAG 1740

GGAGAGTCTT CTGGAGCATA CCCCTGTGGG GTCTCTCAAG GTGCTAAGCT AGCATCTCCG 1800

GCCATATGCC TTCAATGCTT TCGATTTGCC AAAATGTCAT GGACAGAGGG CTTTTCTTCC 1860

AAAGTGGGCA AAGAGCTGCT TCATCCTGTC TATCCCCATC CTTCAGTTAT GTTGCAACCA 1920

TGGGCCTGTG GGCATTACGA ACTCAAATAC TCAGATACAT CCTGCCTGCA TCAGCTAGAG 1980

ATCTTTCAGA AAGACCACAA GGAATGCTTT TATACTTGCT GTCCAGGGAA ACTGACCATT 2040

CATGGGTTCT ACACCTATGT ACTAGTCTTC TTAATTGGAA AACTTAAAGA GCAGTACTGT 2100

GTGCTAAAGA AAACTGTGAG CAGGAGCCTG GGGGAGGGGA AAAATTTCTA TCATGATGGC 2160

CTCCATAGGC CAAGTTCTCA TCACTGTGCA GAACAGAGTG AAATGCATCC TGCTCTGTGT 2220

ATTATGCTTC ATGAGCTCAC TTGTGTTATT GCAGGACAAT TTTATTTTGG TACTTCTGAG 2280

TTAGTCAGTG AGGGAATGGT TATTTTCTCA GAAATGCTAG AGAGCAAGAT TTTCAGGGCA 2340

GGGACCATGA AACAGGGATC TGGTGTATTC ACCCCAAGGG ATATTATCTG TAGATGTATG 2400

AGAGAGATTT CTTCAGATAT AAACTCCTGT GCTCTAACTT CAGTCTTTCA GTCTAAATCT 2460

TCTGTTAAAA AAAAAAAAAG AAAGAAAAAG AAAAAAAAAA AAAAGGAGAA AATCAAGCCA 2520

GGAGCTGTAC TGTTATGTTA TCGGTCTTCT AAGAGAACTA ATGGTGTAGA CCATCACAGT 2580

GGTCCTTCCA TTTTGCAGCC TCCATGCTGT AAATATAATA GCAAGAATCA ATGGCCTGAG 2640

ACAAGGATGA TTGGGGTTCA CAGAAATGGA AATAAACTTT CTTCTTTTTA CACAACTATG 2700

TCCCCATGTA CAGCTTCAAG TAACAGTTCT GTGCCAGTGG GAGAAAGTTA TTTTGTAGAT 2760

AACTACAGAT GGTCCCACCC CCATTCTCTT CTCCCCCTTC TCCACTCCCC TTCTCCACCT 2820

AGCTTTCCTA CCCCCCTTTT TTCTCGTCCT GCATGTTATC AAACATGGAA CCTACATTCT 2880

CAACCACCTC TTCCAGAGAA AAAGAGGTCC TCTGAAGGGG ACCATTCCTT TGTCTCCATC 2940

TCACCTTCTT CAAGTGGTTT CTCAAGCCCC CACAGTGGAA GCACAATCAG CATCCCCTTC 3000

CCAAGTGTTC TTCCAGATTT CTCGAACACT GGAAAGACTT CCCTGTTGCC AGAAAACACA 3060

GCAGAGAAAC AAGTGACTGT AAAATTTGTC CAGGACACAT CCAAGTTTTG GTATAAACCA 3120

GATATTTCAA GAGAACAAGC CATTGCTGTT CTCAAGGACA AGGAGCCTGG GTCATTTGTT 3180

GTTCGAGACA GTCATTCTTT CCGGGGAGCC TATGGACTAG CAATAAAAGT TGCTGTACCA 3240

CCTCCTTCTG TGCTGCAGAT GAACAACACA GTTGGAGATT TGTCAAATGA ACTTGTAAGG 3300

CATTTTCTGA TTGAATGCTC TCAGAAGGGG GTTCACTTGA AAGGATGCCC AAATGAACCA 3360

TGCTTTGGGA GTTTGACTGC TCTGGTGTAC CAGCATTCCA TTACTCCACT GGCATTGCCC 3420

TGTAAACTCC TCATCCCAAA CAGAGATCCA TTGGAAGAGA TGGCAGAAAC TTCTCCACAG 3480

ACTGCTGCAA ACTCAGCAAC AGAGCTTCTC AAACAGGGTG CAGCATGTAA TGTTTGGTAT 3540

CTGAATTCAG TGGAGATGGA GTCCCTCACA GGCTACCAGG CAGTACAGAA AGCCTTGAGC 3600

CTGACGCTGA TGCAAGATCC TTCTCCCATC TCAACCATTG TCCATTTCAA GGTGTCTGCA 3660

CAGGGAATCA CGCTAACAGA TAATCAAAGA AAACTCTTTT TTCGGCGACA TTATCCAGTC 3720

AACACTGTTA TTTTCTGTGC TTTGGATCCA CAAGACAGAA AATGGACATC AAGATGGATG 3780

AAAGATGGCC TTTCTGCAAA AGTATTCGGG TTTGTTGCTA GGAAGCAAGG CAGTGGCACA 3840

GACAATGTGT GCCACCTATT TGCAGAGCAT GATCCAGAGC AACCTGCCAG CGCCATTGTG 3900

AATTTTGTGT CAAAGGTCAT GATTGGATCC CAGAAGAAGA TCTGA 3945

Domain Profile

S: 2     rltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcser  61

         +++e+g++ldlty+teriiavsfPa+ +ee+y  nl++v r+l+skh n+y++ nl se+

Q: 7     HIMEEGYELDLTYITERIIAVSFPADCSEETYLHNLQDVTRMLKSKHGNNYLVLNL-SEK  65

         689*****************************************************.***

S: 62    rydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvi  121

         rydltkln+k++++g++dl+aP+l+k+++ick+++ Wl+ d+++vvv+hckgg+gr+Gv+

Q: 66    RYDLTKLNPKIMDVGWPDLHAPPLDKMCTICKAMESWLNSDPQRVVVIHCKGGRGRIGVV  125

         ************************************************************

S: 122   vcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         +++y++++ +s++ad+ald+f+++++ +dkv++  qPsq+ryv++ s+ll+g

Q: 126   ISSYMHFTSVSTSADQALDRFAMKKFFDDKVSALMQPSQKRYVQFLSGLLSG  177

         *************************************************987

Domain Sequence
(FASTA)

HIMEEGYELD LTYITERIIA VSFPADCSEE TYLHNLQDVT RMLKSKHGNN YLVLNLSEKR 60

YDLTKLNPKI MDVGWPDLHA PPLDKMCTIC KAMESWLNSD PQRVVVIHCK GGRGRIGVVI 120

SSYMHFTSVS TSADQALDRF AMKKFFDDKV SALMQPSQKR YVQFLSGLLS G 171

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016477	; P:cell migration
GO:0008284	; P:positive regulation of cell proliferation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.

Prints

Created Date

20-Feb-2013