EKS-GAG-00349

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00349

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	476.2	2.6E-143	14	275	262

Status

Unreviewed

Ensembl Protein

ENSGALP00000020557

UniProt Accession

F1NUX5;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK1

Gene Synonyms/Alias

DAPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012608	ENSGALP00000020557	ENSGALT00000020586
ENSGALG00000012608	ENSGALP00000005270	ENSGALT00000005280

Organism

Gallus gallus

Functional Description

Protein Length

408

Protein Sequence
(FASTA)

MTVFRQENLE EHYETGEDLG SGQFAVVKKC REKSTGQQFA AKFIKKRRTK SSRRGVGRED 60

IEREVSILKE IRHPNVITLH DVYENKTDVI LILELVAGGE LFDFLAEKES LTEEEATEFL 120

KQILNGVQYL HSLQIAHFDL KPENIMLLDK NVPKPRIKII DFGLAHKIDF GNEFKNIFGT 180

PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGE TKQETLANVS AVNYEFEEEF 240

FSNTSALAKD FIRRLLVKDP KKRMTIQDSL LHPWIKPKDT QQALSRKASA VNMEKFKKFA 300

ARRKWKQSVR LISLCQRLSR SFLSRSNMSV ARSDDTLEEI DFHGTPPLLI AAGCGNIQML 360

QLLLKRGSRI DVQDKAGSNA IYWASRHGHI ETLKFLNENK CPLDVKDK 408

Nucleotide Sequence
(FASTA)

ATGACGGTGT TTCGGCAGGA GAACCTGGAG GAGCACTATG AGACCGGCGA GGACCTCGGC 60

AGTGGGCAGT TTGCTGTAGT GAAAAAATGC CGTGAAAAAA GCACTGGTCA GCAGTTTGCA 120

GCAAAATTCA TCAAGAAGCG GAGAACAAAA TCTAGCCGAC GTGGTGTGGG CCGGGAAGAT 180

ATTGAGCGAG AAGTCAGCAT TCTCAAAGAG ATTCGACACC CTAATGTGAT CACTCTGCAT 240

GATGTTTATG AGAACAAAAC AGATGTCATT CTTATTCTGG AACTTGTTGC AGGTGGAGAA 300

CTCTTCGACT TCTTGGCTGA AAAAGAGTCC CTTACAGAGG AGGAAGCCAC AGAATTTCTC 360

AAGCAAATAC TTAATGGTGT TCAGTATCTC CATTCTCTTC AAATTGCCCA CTTTGATCTA 420

AAGCCTGAAA ACATAATGTT GTTGGACAAA AATGTACCAA AGCCTCGAAT CAAGATTATT 480

GACTTCGGGT TAGCACACAA AATTGATTTT GGAAATGAAT TCAAAAATAT TTTTGGAACA 540

CCAGAGTTTG TTGCTCCTGA AATAGTAAAT TATGAGCCTC TTGGTCTTGA AGCAGATATG 600

TGGAGCATTG GTGTAATAAC TTACATCCTT CTGAGTGGTG CATCACCATT TCTTGGAGAA 660

ACCAAGCAGG AAACATTAGC AAATGTGTCT GCTGTGAATT ATGAATTTGA AGAAGAATTC 720

TTCAGTAATA CCAGTGCCCT AGCTAAAGAT TTTATACGAA GACTTCTAGT CAAGGATCCA 780

AAGAAGAGAA TGACTATTCA AGATAGTTTG CTGCATCCTT GGATCAAGCC TAAAGACACT 840

CAGCAAGCAC TTAGTAGGAA AGCATCTGCA GTGAATATGG AGAAATTCAA GAAGTTTGCA 900

GCACGGCGAA AATGGAAACA ATCAGTACGC TTGATATCCT TGTGCCAAAG ATTATCAAGA 960

TCCTTCTTGT CCAGAAGTAA TATGAGTGTT GCTAGGAGTG ATGATACTCT GGAGGAAATA 1020

GATTTTCATG GAACACCTCC ACTACTCATT GCTGCTGGCT GTGGGAACAT TCAGATGCTT 1080

CAGTTGCTTC TAAAGCGTGG ATCCCGTATT GATGTCCAAG ATAAGGCCGG ATCTAATGCA 1140

ATCTACTGGG CTTCTCGACA TGGTCATATA GAAACACTGA AATTTCTGAA TGAGAATAAG 1200

TGTCCTCTGG ATGTTAAGGA TAAG 1224

Domain Profile

S: 2     etgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirs  61

         etg++lgsG+favv+kcrekstG+++aakf+kkrr+kssrrgv re+ierev++lkeir

Q: 14    ETGEDLGSGQFAVVKKCREKSTGQQFAAKFIKKRRTKSSRRGVGREDIEREVSILKEIR-  72

         789********************************************************.

S: 62    epnvinlhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylhs  121

         +pnvi+lh+vyenk+dvililelvaGGelfd+laekesl+eeeate+lkqil+gv+ylhs

Q: 73    HPNVITLHDVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVQYLHS  132

         ************************************************************

S: 122   kkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnye  181

          +i+h+dlkPeni+lldk+vpk++ik+idfGl++ki+ g+e+k+i+GtPefvaPeivnye

Q: 133   LQIAHFDLKPENIMLLDKNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYE  192

         ************************************************************

S: 182   plsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfi  241

         pl+le+dmwsiGvityillsgasPflG+tkqetl+n+savn++f+ee+fs++s lakdfi

Q: 193   PLGLEADMWSIGVITYILLSGASPFLGETKQETLANVSAVNYEFEEEFFSNTSALAKDFI  252

         ************************************************************

S: 242   rrllvkdpekrltieeclehswl  264

         rrllvkdp+kr+ti+++l h+w+

Q: 253   RRLLVKDPKKRMTIQDSLLHPWI  275

         **********************8

Domain Sequence
(FASTA)

ETGEDLGSGQ FAVVKKCREK STGQQFAAKF IKKRRTKSSR RGVGREDIER EVSILKEIRH 60

PNVITLHDVY ENKTDVILIL ELVAGGELFD FLAEKESLTE EEATEFLKQI LNGVQYLHSL 120

QIAHFDLKPE NIMLLDKNVP KPRIKIIDFG LAHKIDFGNE FKNIFGTPEF VAPEIVNYEP 180

LGLEADMWSI GVITYILLSG ASPFLGETKQ ETLANVSAVN YEFEEEFFSN TSALAKDFIR 240

RLLVKDPKKR MTIQDSLLHP WI 262

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005737	; C:cytoplasm
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006915	; P:apoptotic process
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:2000310	; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR000488	; Death.
IPR020676	; Death-assoc_prot_kinase.
IPR011029	; DEATH-like.
IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF12796	; Ank_2; 1.
PF00531	; Death; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00248	; ANK; 2.
SM00005	; DEATH; 1.
SM00220	; S_TKc; 1.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 1.
PS50017	; DEATH_DOMAIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013