EKS-GAG-00174

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00174

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	506.5	2.0E-152	4	284	281

Status

Unreviewed

Ensembl Protein

ENSGALP00000020807

UniProt Accession

E1BWM1;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012770	ENSGALP00000020807	ENSGALT00000020836

Organism

Gallus gallus

Functional Description

Protein Length

625

Protein Sequence
(FASTA)

MNRYTIMKQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNMMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCIGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSIYSSP 180

IDIWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYHL SSAMNFRFPQ 240

CVPISLKTLI PNASSEAIQL MSDMLNWNPK KRPTASQALK YPYFQVGQVL GPPPQYLEKQ 300

TPIKPVQPTE PKPTLPKLEA VSKPEPLSSP DEPDKTQPQP LSKANHQPLQ QIQLPQNTAN 360

QQVSKQQQTQ AQPFFPAISK DSSGNGTVGP KSCRRRWGQT LIKAVDSWDE LDDAEFGMSC 420

SKKPSIALLK EKKNKECPFS VPEPKASHCI QPGVENKVLM RNDSGRSNTS AKQYYLRQSR 480

YLPGVNPKTV SLVAVNKEGS QGTWNNQLFS KPLAHVGEGL HFNRNNTGRH IGNHGSWTTG 540

AAYNPSGGYI PSFHKKEVGS AGQRIQLAPI GPSVSDYSWK TKAARAQLAG PTYNSAKNMN 600

ILSHAPAIQP VHGRTDWMAK YGGHR 625

Nucleotide Sequence
(FASTA)

ATGAACCGTT ACACAATCAT GAAGCAGCTG GGTGATGGCA CCTATGGCAG TGTCTTGATG 60

GGGAAAAGCA ATGAATCAGG AGAGCTTGTG GCCATCAAAC GAATGAAAAG GAAGTTCTAT 120

TCATGGGATG AGTGCATGAA TTTGAGAGAA GTCAAGTCTC TGAAGAAGTT AAATCATGCC 180

AATGTAATAA AATTGAAAGA AGTCATAAGA GAAAATGACC ACCTTTACTT TGTGTTTGAA 240

TACATGAAGG AAAATCTCTA TCAATTGATG AAGGACAGAA ACAAGTTGTT CCCTGAGTCA 300

GTCATCAGAA ACATGATGTA TCAGATATTG CAAGGGTTAG CTTTCATCCA TAAACACGGA 360

TTTTTTCATA GAGACATGAA GCCTGAAAAC CTTCTTTGCA TTGGTCCAGA ACTTGTAAAA 420

ATAGCTGATT TTGGTTTGGC TAGAGAGCTG AGATCTCAGC CACCATATAC AGATTATGTG 480

TCTACCAGGT GGTACCGTGC TCCTGAAGTT TTGCTGCGAT CATCTATTTA TAGCTCACCT 540

ATTGATATTT GGGCAGTTGG CAGCATAATG GCTGAATTAT ACACACTAAG ACCCCTTTTC 600

CCAGGCACAA GTGAAGTAGA TGAGATCTTC AAAATTTGCC AAGTATTAGG GACTCCAAAG 660

AAGAGTGACT GGCCAGAAGG ATATCACCTC TCTTCTGCCA TGAATTTCCG TTTCCCACAG 720

TGTGTCCCTA TAAGTTTAAA AACTCTCATC CCAAATGCAA GCAGTGAAGC CATACAGCTT 780

ATGAGTGATA TGCTGAACTG GAATCCAAAG AAGAGACCTA CAGCAAGTCA GGCACTGAAG 840

TACCCATACT TTCAAGTTGG CCAAGTTTTA GGACCTCCTC CACAGTATTT GGAGAAGCAG 900

ACTCCTATTA AACCAGTGCA GCCAACAGAA CCAAAGCCAA CTTTACCCAA ACTGGAAGCT 960

GTATCCAAGC CAGAACCTCT GTCTTCCCCT GATGAACCTG ACAAAACACA GCCACAGCCC 1020

CTGTCAAAGG CTAATCACCA GCCTCTCCAG CAAATTCAGT TGCCTCAGAA TACAGCTAAC 1080

CAGCAAGTAT CAAAACAGCA GCAGACACAG GCACAGCCTT TTTTTCCAGC TATCAGTAAA 1140

GACTCATCTG GGAATGGCAC AGTAGGTCCT AAAAGTTGCA GGAGACGATG GGGTCAGACT 1200

TTGATAAAGG CTGTGGACAG CTGGGATGAG TTGGATGATG CTGAATTTGG AATGTCATGT 1260

TCCAAGAAGC CTAGCATTGC ACTGTTAAAA GAAAAGAAAA ACAAGGAATG TCCTTTTAGT 1320

GTGCCAGAAC CAAAAGCTTC ACACTGTATC CAGCCAGGAG TGGAAAATAA AGTTCTGATG 1380

AGAAATGATT CTGGAAGATC CAATACATCA GCAAAACAGT ACTATCTAAG ACAATCAAGA 1440

TATCTGCCAG GTGTAAATCC TAAGACTGTC TCTTTAGTAG CAGTCAATAA AGAAGGATCT 1500

CAGGGAACCT GGAACAACCA GCTGTTTTCC AAGCCATTGG CACATGTTGG AGAAGGATTG 1560

CATTTCAACA GAAACAATAC AGGCAGACAC ATAGGAAACC ATGGTAGTTG GACCACAGGA 1620

GCTGCTTACA ACCCATCAGG AGGATACATC CCCTCCTTTC ATAAGAAAGA AGTTGGATCA 1680

GCTGGACAAC GGATACAGCT AGCTCCTATT GGTCCGTCTG TATCTGATTA TTCCTGGAAA 1740

ACCAAAGCTG CTCGTGCTCA GTTAGCAGGC CCTACTTACA ATTCAGCAAA AAACATGAAT 1800

ATTTTATCTC ATGCACCAGC AATTCAGCCA GTACATGGCA GAACAGACTG GATGGCTAAA 1860

TACGGAGGAC ACAGATAG 1878

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTIMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+v+e+m+enlyql+kdr+kl++es++++++yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNMMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l+ g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDMKPENLLCIGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSIYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+l+sa+n++fpq

Q: 181   IDIWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYHLSSAMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++++slktl++nas+ea++l++d+l+++P++r+ta+qalkypyf

Q: 241   CVPISLKTLIPNASSEAIQLMSDMLNWNPKKRPTASQALKYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTIMKQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR NKLFPESVIR NMMYQILQGL AFIHKHGFFH 120

RDMKPENLLC IGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSIYSSPIDI 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYHLSSA MNFRFPQCVP 240

ISLKTLIPNA SSEAIQLMSD MLNWNPKKRP TASQALKYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0030496	; C:midbody
GO:0072686	; C:mitotic spindle
GO:0005634	; C:nucleus
GO:0001917	; C:photoreceptor inner segment
GO:0001750	; C:photoreceptor outer segment
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0003713	; F:transcription coactivator activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013