EPS-GAG-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	206.3	7.2E-61	651	896	246

Status

Unreviewed

Ensembl Protein

ENSGALP00000036383

UniProt Accession

F1NJB8;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000012888	ENSGALP00000036383	ENSGALT00000037175
ENSGALG00000012888	ENSGALP00000020988	ENSGALT00000021018

Organism

Gallus gallus

Functional Description

Protein Length

1181

Protein Sequence
(FASTA)

SGKPHSIGSS ERIQLSGMYN VRKGKIHLPV NRWTRRQAIL CGTCLIVSSV KESQTGKMHV 60

LPLIGGKVEE VKKHQHCLAF SSSGPQSQTY YICFDNFTEY LRWLRQASKV ASQRISSVDL 120

SCCSLEHLPA NLFYSQDLTH LNLKQNFLKL NPSPSASRAL SELQRFTKLK SLNLSNNNLG 180

DFPLAVCSIP TLTELNVSCN ALRNVPAVVG EMHNLQTFLL DGNFLQSLPD ELEHMHQLSY 240

VSLSFNEFTD IPGVLEKLTA MDKLCMSGNC VDTLNLQVLK RMPHIKHVDL RLNSIRRLEA 300

DEIDFLHHVT QLDLRDNKLG ELDATIFNNV EVLHCERNQL VTLKISGYFL KALYASSNEL 360

VHLDVYPVPN YLTYMDISRN HLENLPEWVC DSKKLEVLDV GHNRISELPA RLFYNSSLRK 420

LLAGHNLLGR LPDRLERTQV EVLDVQHNQL LELPPNLLLK ADSLRFLNAS ANKLEMLPPA 480

TLSEETHSIL QELYLTNNNL TDKCVPLLTG HPHLKILHMA YNRLQSFPAS KMAKLEELEE 540

IDISGNKLKA IPTTIMNCRR MHTVIAHSNC IEVFPEVMQL SEIKCVDLSC NELSEITLPE 600

NLPPKLQELD LTGNPRLALD HKTLELLNNI RCFKIDQPSA GDASGAPAVW SHGYTEASGV 660

KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ KTKNEEEYMI 720

NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGCFTLT SANVGKCQTV LCRNGKPLPL 780

SRCYVMSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVVPR PHVQSITLTP 840

QDEFFILGSK GLWDSLSMDE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS ISAVVVQLNV 900

TEDSFCCCEL NGVPPPSPGI FPQSVNVVIK DRPADALGMP SSSSGMASEI SSEISTSEMS 960

SEVGSTASDE PPQVAMNESS PAYPGEQRCM LHPVCLSNSF QRQLSSATFS SAFSDNGLDS 1020

DDEEPIEGVF TNGSRVEVEV DIHCSRAKEK QLLQVPVEAS DEGIVISANE DEPGLPKKAE 1080

YSATGTIGRR RGNGSVAPQE RSHNLIEVAT DAPLRKTGGY FAAPAQPDPD DQFIIPPELE 1140

EEVKEIMKQH QEQQQQQQQQ QQQQQRQYQM DHLADYYDTP L 1181

Nucleotide Sequence
(FASTA)

TCAGGAAAGC CCCACAGCAT TGGCAGCTCC GAGCGGATTC AGCTCTCAGG AATGTACAAT 60

GTTCGAAAAG GGAAAATACA TTTGCCAGTC AACAGATGGA CAAGACGTCA AGCTATCCTT 120

TGTGGAACAT GCCTAATTGT CTCATCAGTA AAAGAAAGCC AGACGGGAAA GATGCATGTC 180

CTCCCTTTAA TTGGTGGCAA AGTGGAGGAG GTGAAAAAGC ACCAGCACTG CTTAGCATTT 240

AGCTCTTCTG GACCTCAAAG CCAGACTTAC TACATTTGTT TTGATAACTT CACTGAATAC 300

TTACGATGGC TTCGACAAGC ATCAAAGGTT GCATCACAGC GCATAAGCTC AGTGGATCTT 360

TCGTGCTGCA GCTTGGAGCA TCTGCCTGCC AACTTGTTTT ATAGCCAAGA CCTCACTCAT 420

CTCAATTTAA AGCAGAACTT CCTGAAGTTA AACCCTAGCC CATCCGCAAG CAGAGCACTT 480

AGTGAATTAC AAAGATTCAC CAAGTTGAAG AGCCTTAACC TCTCCAATAA TAATTTAGGA 540

GACTTCCCAC TGGCAGTTTG CAGTATCCCA ACCCTGACGG AGCTCAACGT GTCCTGCAAT 600

GCCCTCAGAA ATGTTCCAGC AGTTGTAGGC GAGATGCACA ACTTGCAGAC ATTTTTGCTG 660

GATGGTAACT TTCTCCAGTC TCTTCCCGAT GAACTGGAGC ATATGCATCA GCTCAGCTAT 720

GTGAGTCTGT CCTTCAATGA ATTCACTGAC ATTCCAGGAG TATTAGAGAA GCTGACTGCT 780

ATGGACAAAC TCTGTATGTC AGGAAACTGT GTGGATACGC TCAACTTGCA AGTGTTAAAA 840

AGGATGCCTC ATATTAAACA TGTGGACCTA AGATTGAATT CAATTAGGAG ATTGGAGGCT 900

GATGAAATAG ACTTTCTCCA CCATGTGACC CAGTTGGACC TCAGAGACAA CAAGCTTGGA 960

GAGCTGGATG CAACAATATT TAACAACGTT GAAGTGTTAC ACTGTGAAAG AAATCAACTG 1020

GTAACTCTGA AAATCAGTGG ATATTTTCTC AAAGCCCTGT ATGCTTCCTC AAATGAACTT 1080

GTTCATCTTG ATGTGTATCC AGTTCCTAAT TACCTGACTT ACATGGATAT TTCTAGAAAT 1140

CATCTGGAAA ACCTGCCTGA GTGGGTATGT GACAGCAAAA AGCTGGAAGT GTTGGATGTT 1200

GGCCACAATC GGATAAGTGA GCTGCCTGCC CGGTTGTTTT ACAACAGCAG CTTGCGTAAA 1260

CTGCTGGCAG GACATAACTT GTTAGGAAGG CTACCAGATC GTCTTGAACG AACGCAAGTG 1320

GAGGTCCTGG ATGTGCAACA CAACCAGCTC CTTGAACTGC CACCTAACCT ACTTTTGAAA 1380

GCTGACAGCC TGAGATTTCT TAACGCCTCC GCCAACAAAC TGGAAATGCT TCCCCCAGCC 1440

ACTCTTTCTG AGGAGACCCA TAGCATCTTA CAGGAGTTGT ATTTGACCAA TAACAACCTC 1500

ACGGATAAGT GTGTACCCTT GTTAACAGGC CATCCACACC TGAAAATCTT GCACATGGCC 1560

TACAATCGCC TACAGAGCTT CCCTGCAAGC AAAATGGCCA AGCTGGAAGA GTTGGAGGAA 1620

ATTGATATTA GTGGTAACAA GCTGAAAGCC ATTCCGACAA CCATCATGAA CTGTAGGCGC 1680

ATGCATACTG TAATTGCTCA CTCCAACTGC ATTGAAGTCT TCCCAGAAGT CATGCAGCTT 1740

TCTGAAATAA AGTGTGTGGA TCTAAGCTGC AATGAACTGA GTGAAATCAC ACTGCCTGAA 1800

AACTTGCCTC CAAAACTGCA AGAGCTGGAC CTGACTGGAA ACCCCAGATT GGCCTTGGAT 1860

CACAAAACCC TTGAGCTGCT GAACAATATC CGTTGTTTCA AGATTGACCA GCCCTCGGCT 1920

GGTGATGCTT CAGGAGCTCC AGCTGTGTGG AGTCACGGTT ACACAGAGGC GTCAGGAGTT 1980

AAGAACAAGT TGTGCGTGGC AGCCCTGTCA GCCAATAACT TCTGTGACAA CAGAGAGGCA 2040

CTTTATGGTG TTTTTGACGG TGACCGCAAT GTGGAAGTAC CATATCTGTT GCAGTGCACC 2100

ATGAGTGACA TCTTGGCAGA AGAGCTACAG AAAACAAAAA ATGAAGAGGA ATATATGATC 2160

AACACTTTCA TTGTTATGCA GAGGAAACTT GGAACAGCTG GACAAAAACT TGGAGGCTCT 2220

GCTGTCCTTT GCCATATAAA ACATGATCCC ATGGACCCTG GCGGATGCTT CACGTTAACC 2280

TCAGCAAATG TGGGGAAGTG CCAAACCGTT CTCTGCCGGA ATGGGAAACC TCTGCCTTTG 2340

TCCAGGTGTT ATGTGATGAG TTGTGAAGAA GAGCTGAAGA GGATTAAGCA GCATAAGGCC 2400

ATTATCACAG AGGATGGCAA AGTGAATGGT GTGACAGATT CAACGAGAAT CTTGGGATAC 2460

ACATTCCTTC ACCCAAGTGT TGTGCCGCGT CCTCACGTCC AGTCCATTAC CTTAACTCCA 2520

CAAGATGAGT TCTTCATTCT GGGGAGCAAG GGGCTGTGGG ACAGCCTCTC GATGGATGAG 2580

GCAGTGGAAG CAGTCAGAAA CGTGCCTGAT GCACTGGCAG CTGCCAAGAA GCTTTGCACT 2640

TTGGCCCAAA GTTACGGCTG CAACGACAGT ATCAGTGCGG TTGTGGTTCA GCTCAATGTT 2700

ACGGAGGACA GCTTCTGCTG CTGTGAACTT AATGGGGTCC CACCCCCCAG CCCAGGCATT 2760

TTCCCCCAGT CTGTCAACGT GGTCATCAAG GACAGGCCAG CGGATGCTCT TGGGATGCCG 2820

TCTTCAAGCA GCGGCATGGC TTCAGAGATC AGCAGCGAGA TCTCCACCTC AGAAATGAGC 2880

AGCGAGGTGG GGTCCACAGC CTCCGATGAA CCTCCACAGG TAGCCATGAA CGAGAGCAGC 2940

CCGGCCTACC CCGGGGAGCA GCGCTGCATG CTGCATCCCG TCTGCCTGTC CAACTCCTTC 3000

CAGCGGCAGC TCTCCAGCGC CACGTTCTCC AGCGCCTTCT CCGACAACGG CCTTGACAGC 3060

GATGACGAGG AGCCGATAGA GGGGGTATTC ACCAACGGCA GCCGCGTGGA AGTGGAGGTG 3120

GACATCCACT GCAGCCGAGC GAAGGAGAAG CAGCTTCTCC AAGTGCCTGT GGAAGCCAGT 3180

GATGAAGGTA TTGTCATCAG TGCCAACGAA GATGAGCCCG GCCTTCCCAA GAAAGCCGAA 3240

TATTCTGCCA CAGGCACCAT AGGGCGTCGG AGGGGCAACG GCTCTGTGGC ACCCCAAGAG 3300

AGAAGCCATA ATTTGATTGA AGTTGCAACA GATGCACCGC TCAGAAAAAC AGGGGGATAT 3360

TTTGCTGCTC CGGCACAGCC GGACCCAGAT GACCAATTCA TCATCCCACC AGAGCTGGAA 3420

GAAGAGGTCA AGGAGATCAT GAAACAGCAC CAGGAACAGC AACAACAGCA GCAGCAGCAG 3480

CAACAGCAGC AGCAACGGCA GTACCAGATG GACCACCTGG CAGACTACTA CGATACGCCA 3540

CTA 3543

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 651   SHGYTEASGVKNKLCVAALSANNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  705

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 706   AEELQ----KTKNEEEYMINTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpgg  755

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv+

Q: 756   cfTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDG--KVNGVTD  813

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s  eav++vr+v +

Q: 814   STRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPD---  870

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 871   -ALAAAKKLCTLAQSYGCNDSISAVVV  896

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMI NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGCFTLT SANVGKCQTV 120

LCRNGKPLPL SRCYVMSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVVPR 180

PHVQSITLTP QDEFFILGSK GLWDSLSMDE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>